Drug

Mechanism of action Generic: Celecoxib selectively Brand: Celebrex damages formation of Classification: antiinflammatory inflammatory response and does not affect production of Available form: prostaglandins capsules(100,200,400mg) regulating Route: kidney blood PO circulation and integrity of the gastrointestinal mucous coat

Indication Rheumatoid arthritis, osteoarthritis, acute pain and primary dysmenorrhea

Adverse reaction and Side effects eadaches, dizziness, insomnia, rash, signs of rhinitis, abdominal pain ,diarrhea, dyspepsia flatulence, nausea, GI bleeding, back pain, upper respiratory tract infection

Contraindication Nursing responsibilities Hypersensitivity. Assess patient for Allergy to other risk factor of GI NSAIDs and bleeding sulfanilamides, Monitor patient for severe for evidence of impairments of overt and occult liver and kidneys bleeding, function, cardiac Assess patient for insufficiency, CV status, history gastric and particularly recent duodenitis ulcer heart surgery,MI or in acute phase stroke Monitor patient for liver toxicity Use cautiously in patients at a high risk for CV complications Before therapy rehydrate patient Instruct patient to take drug with food if stomach upset occurs.

Drug

Mechanism of action

Indication

Adverse reaction and Side effects

Contraindication Nursing responsibilities

Generic: Felodipine Brand: Plendil, Plendil ER, Agon, Renedil Classification: Anti-hypertensive Available form: tablet 2.5mg, 5mg, 10mg Route: PO

Felodipine Hypertension prevents calcium from being released within the muscle cells of the small arteries and thereby causes the muscles to relax and the arteries to dilate or expand.

CNS: Asthenia, dizziness, headache, paresthesia CV: chest pain, flushing, palpitations, peripheral edema EENT: gingival hyperplasia,rhinorrhea, pharyngitis GI: abdominal pain, constipation, diarrhea, nausea Musculoskeletal: back pain, muscle cramps Respi: Cough, upper respiratory infection Skin: rash Peripheral edema (swollen ankles and feet) and headache are the most common side effects of felodipine

Contraindicated in patients hyperstensive to drug or any of its components Use cautiously in patients with heart failure, particularly those receiving beta blockers, and in patients with impaired hepatic function

Assess patients blood pressure before starting therapy, and reassess regularly. Be alert for adverse reactions and drug interactions Drug may be given with or without food Instruct patients swallow tablets not tocrush or chew them Tell patient to take drug even when he feels better, to watch hist diet and to check with prescriber or pharmacist before taking other drugs, including over the counter drugs or herbal medicines.

Drug Generic: Cefuroxime Synonyms: Cefuroxime Axetil Cefuroxime Sodium Brand: Axet, Ecoceft, Oxime, Ceftin, Zinaceft

Mechanism of action Cefuroxime is a semisynthetic cephalosporin antibiotic, chemically similar to

Indication Treatment of infections caused by staphylococci, group B streptococci, H.

Adverse reaction and Side effects CNS: Dizziness, headache, malaise, paresthesia GI: Abdominal cramps, anal pruritus, anorexia, diarrhea, dyspepsia, glossitis nausea,pseudomembranous

Contraindication Nursing responsibilities Patients Assess patients hypertensive to infection before drug or other therapy and cephalosporins regularly thereafter Use cautiously on If adverse GI patients with reactions occur,

Classification Available form: Cefuroxime axetil Suspension:125mg/5ml,250 mg/5ml Tablets:125mg, 250 mg, 500 mg Cefuroxime sodium Infusion: 750mg, 1.5g premixed, frozen solution Injection: 750mg, 1.5g Route: PO, IV, IM

penicillin. It is effective against a wide variety of bacteria organisms, such as Staphylococcus aureus, Streptococcus pneumoniae, Haemophilus influenzae, E. coli, N. gonorrhoeae, and many others

influenzae (type A and B), E. coli, Enterobacter, Salmonella, and Klebsiella; treatment of susceptible infections of the lower respiratory tract, otitis media, urinary tract, skin and soft tissue, bone and joint, sepsis and gonorrhea

colitis, tenesmus, vomiting GU: candidiasis, pruritus Hematologic: Eosinophilia, Hemolytic Anemia, thrombocytopenia, transient neutropenia Respiratory: Dyspnea

history of sensitivity to penicillin and in patients with renal impairment

monitor patients hydration Advise patient to take oral drug with food to enhance absorption Inject deep into large muscle mass, such as gluteus maximus or lateral aspect of thigh Instruct patient to take drug exactly as prescribed, even after he feels better