Professional Documents
Culture Documents
Note: Make sure you have watched the attached Google Classroom videos and the article too. This will
give you the required background to thoughtfully respond to the questions below.
2. Please summarize the video “Why do Organ Transplants Fail So Often?” in a paragraph or two.
Make sure to include ideas from the entire video.
Organ transplants are performed countless times each year and save people’s lives, but many of
these transplants are rejected from the host’s body. Matches are rare and rejections occur very often
such as with the difficult transplants including the kidney having a 70% chance of success. With an
individual receiving an organ transplant, there are different types of rejections that may occur:
hyperacute, acute, and chronic. Rejection occurs throughout the years after having the surgery. Our
immune system is incapable of distinguishing between a new organ or a virus making it difficult to find
a donor. Signs that our body is rejecting the organ include swelling, redness, and overall feeling unwell.
With immunosuppressive drugs, it aids in lowering the immune system to prevent the body from
rejecting the new organ.
3. Why are transplanted organs often rejected, when placed in another patient? Be specific.
Transplanted organs rarely match and are often rejected when placed in another due to the fact
that our body recognizes the transplanted organ as foreign and a possible danger to ourselves
which leads to our immune system attempting to destroy the organ. An important part of our
immune system that contributes towards the rejection of the organ is the major
histocompatibility complex (MHC). The MHC’s role is to differentiate between which is our
body’s cell and what is foreign. There are many gene combinations on the MHC which makes
finding an organ donor difficult and leads towards the destruction of the foreign organ.
4. What are two questions you have about organ transplantation that are not answered in the
videos or article?
a. What medical tests are done and factors are considered when determining a possible organ
donor for the transplant to be performed?