ACTIVE LEARNING TEMPLATE: Medication

STUDENT NAME______________________________________
Zyloprim (Allopurinol)
MEDICATION___________________________________________________________________________ REVIEW MODULE CHAPTER____________

CATEGORY CLASS__C
_____________________________________________________________________

PURPOSE OF MEDICATION

Expected Pharmacological Action Therapeutic Use

Reduces uric acid production by inhibiting Gout, hyperuricemia, uric acid nephropathy
xanthine oxidase. preventionReccurent calcium oxalate calculi

Complications Medication Administration

Nausea, vomiting, abdominal pain, renal failure, acute 200-800 mg P.O daily Max 800
gout attack, rash, maculopapular rash mg daily Peak—1 1/2
hr200-400 mg/m^2 daily I.V as
a single infusion or in equally
divided doses q6,8,12 hrs
Peak—30 mins 1/2 life—1-2 hrs

Contraindications/Precautions
Hypersensitivity to Zyloprim and its components. HTN
(uncontrolled)
Nursing Interventions
Obtain baseline CBC and uric
acid level, as ordered, and
review results of renal and liver
function tests before and during
Zyloprim therapy.
Interactions Reconstitute and dilute I.V.
CNS: confusion, dizziness, headache, hemiplegia, preparation to a concentration
hypothesia, malaise, parethesia, restlessness, seizures,
seretonin syndrome CV: angina pectoris, coronary artery
vasospasm, htn, ischemia, MI GI: Abdominal pain or
discomfort, colitis, nausea
Client Education
Do not take to treat nonmigraine
headache. Drug may cause
Evaluation of Medication Effectiveness adverse CNS reactions. Notify
Decreased number of gout attacks. Decreased pain from prescriber if pregnancy is
gout. Decreased uric acid level suspected or occurs

ACTIVE LEARNING TEMPLATES