Control of Microorganisms

I. Terminology
A. Sterilization, Sterile Substances
B. Disinfectant
C. Antiseptic
II. Where Do We Control Microbes?
A. Nonliving Matrix
B. Living Matrix
III. Control in a Nonliving Matrix
A. Physical Methods
i. High Temperature
1. Moist Heat
2. Dry Heat
ii. Low Temperature
iii. Radiation
B. Mechanical Methods
i. Filtration
C. Chemical Methods
Disinfectants
i. Heavy Metals
ii. Halogens
iii. Detergents
iv. Strong Oxidants
IV. Control in a Living Matrix
A. Chemical Methods
Antiseptics
i. Heavy Metals
ii. Halogens
iii. Alcohol
iv. Detergents
v. Strong Oxidants
B. Chemotherapeutic Agents
Antibiotics
i. Broad vs. Narrow Spectrum
ii. Sulfa Drugs
iii. Cell Wall Inhibitors
iv. Cell Membrane Inhibitors
v. Protein Synthesis Inhibitors
vi. Nucleic Acid Inhibitors
C. Antibiotic Resistance
i. Penicillinase & Cell Wall Inhibition
ii. Other Mechanisms