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Orthopedic Reviews 2020; volume 12(s1):8680

of a finger during flexion or extension, pain


and functional limitation.1
Physical therapies for the con-
Correspondence: Sefora Codazza, University
servative treatment of the trig- Pinching of the tendon can lead to Policlinic Foundation A. Gemelli IRCCS,
ger finger: a narrative review nodule formation and patients typically Rome.
present with a locking, popping sensation as Tel.: +393479617903.
E-mail: sefora.codazza@policlinicogemelli.it
Paola Emilia Ferrara,1 Sefora Codazza,1 the nodule catches at the constriction.2
Giulio Maccauro,2 Gianfranco Zirio,2 In some cases, it resolves spontaneously; Key words: trigger finger, physical therapy,
Giorgio Ferriero,3 Gianpaolo Ronconi1 however, if left untreated, trigger digit may conservative treatment.
gradually progress until the affected finger
1
University Policlinic Foundation A.
is permanently locked in flexion. Contributions: the authors contributed equally.
Gemelli IRCCS, Rome; 2Orthopedic and
Histologically, the A1 pulley exhibits
Traumatology Institute, Catholic fibrocartilaginous metaplasia, and in the Conflict of interest: the authors declare no
University of the Sacred Heart, Rome; tendon tissue, areas of hyalinosis, mucoid potential conflict of interests.
3
Istituto Scientifico di Tradate, IRCCS degeneration, and chondral metaplasia are Funding: None
Istituti Clinici Maugeri, Tradate (VA), found.
Italy TF is usually classified as an idiopathic Availability of data and materials: Alla data
condition, but some other etiologic hypotesis are published in the text.
was proposed. It has been postulated that this
disorder is caused by high pressure at the Ethics approval and consent to participate:
Abstract proximal edge of the A1 pulley and the Not applicable.

Trigger finger (TF) disorder is a sudden discrepancy between the diameter of the
Informed consent: Not applicable.
release or locking of a finger during flexion or flexor tendon and its sheath at the metacarpal

ly
extension. Treatments for this disease are head.3 Some authors argue that there is a Received for publication: 11 April 2020.
conservative and surgical, including NSAIDs, possible correlation with hand overuse and Accepted for publication: 17 June 2020.

on
hand splints, corticosteroid injections, repetitive blunt trauma. Other potential risk
physical therapies and percutaneous or open factors include rheumatoid arthritis, diabetes This work is licensed under a Creative
mellitus, carpal tunnel syndrome, Commons Attribution NonCommercial 4.0
surgery. However, the effectiveness about the

e
License (CC BY-NC 4.0).
optimal treatment of TF is still in lack of Dupuytren’s disease, amyloidosis,
evidence. The aim of this study is to
investigate the effectiveness of physical
hypothyroidism, us
mucopolysaccharide
storage disorders, congestive heart failure,
©Copyright: the Author(s), 2020

Licensee PAGEPress, Italy


therapies as conservative treatment for trigger and genetic predisposition.4 However, the Orthopedic Reviews 2020; 12(s1):8680
al
finger. A comprehensive literature search of main etiology is still unclear. doi:10.4081/or.2020.8680
the MEDLINE (via PubMed), Cochrane TF is the most common flexor
ci

Library Databases and PEDro databases has tendinopathy, with highest incidence is
between 52 and 62 years and in women
er

been conducted without limits because few over time. Surgery is associated with longer
papers were published about this argument. (75%).5 Thumb and fourth digit (ring finger)
recovery times and more complications
are the most commonly affected fingers, the
m

The literature search identified four papers in including tendon bowstringing, digital ulnar
PubMed. Two types of physical therapies right hand is more frequently involved
drift, and nerve injuries. 6
om

were used in the conservative management of compared to the left hand 6 and the dominant
hand is more frequently involved compared Recently, extracorporeal shock wave
trigger finger: external shock wave therapy
to the non dominant hand. therapy (ESWT) is getting popular as an
(ESWT) in three papers, and ultrasound
alternative to surgery for the treatment of
-c

therapy (UST) in one paper. ESWT is an Diagnosis of TF is based on history of


pain, morning stiffness, and tenderness on musculoskeletal disorders in patients
effective and safe therapy for the conservative
on

management of TF. It seems to reduce pain the A1 pulley, and on clinical examination. unresponsive to conservative approach.
and trigger severity and to improve functional Treatment aims to eliminate pain and stop ESWT has been reported to be effective in
level and quality of life. UST has proven to triggering. several tendinopathies, such as calcific
N

be useful to prevent the recurrence of TF TF’s therapy can be divided into tendinopathies of the shoulder.8 lateral
symptoms. Even if the results suggest the conservative and surgical treatment. The epicondylitis of the elbow,9 patellar
effectiveness of ESWT and UST for TF, currently accepted conservative treatments tendinopathy,10 hamstrings tendinopathy 11
future studies are necessary to understand the included medications, usually oral NSAIDS and plantar fasciitis.12
characteristics of the optimal treatment and local corticosteroid injection (CI), with A variety of treatments have been
protocol for trigger finger. rehabilitative interventions, including described in literature for TF, but the most
extension splint, physiotherapy programs, effective treatment is still under debate.
with mobilization and stretching exercises
Acknowledging the possible
and physical therapy.6 Surgical treatment
complications associated with surgery, the
Introduction involves percutaneous and open release of
fact that guidelines recommend surgery only
the A1 pulley, and it’s recommended only
Trigger finger (TF), also known as when TF has been unresponsive to when conservative treatments have failed,
stenosing tenovaginitis or tenosynovitis, is conservative therapies. CI and surgery are the aim of this review was to investigate the
an hand disorder due to hypertrophy at the reported to be effective for the remission of effectiveness of physical therapies as
intersection of the tendon with its pulley; the symptoms. CI have the greatest success rate conservative treatment for trigger finger.
subsequent constriction of the tendon among conservative treatments,7 but they are
prevents it from gliding through ligament’s effective only for some patients, and could
pulley, causing a sudden release or locking predispose to tendon rupture when repeated

[page 90] [Orthopedic Reviews 2020; 12(s1):8680]


Review

physical therapies in TF. Any papers were Vahdatpour et al.13 recruited 19 subjects with
Materials and Methods selected in PEDro and Cochrane Library trigger finger disorder. Each patient was
Databases. Of the four total papers one is an treated with ESWT in three sessions with a
A comprehensive literature search of the
interventional study,13 one is a retrospective 1-week interval. The treatment protocol for
MEDLINE (via PubMed), Cochrane Library cohort study,14 and two are prospective each session consisted in two parts: radial
Databases and PEDro databases was RCTs.7,15 extracorporeal shock wave therapy (rESWT)
conducted using the following search terms: Two types of physical therapies were with 1000 shocks, at an energy flux density
“trigger finger” OR “physical therapy” OR found to be used in the conservative of 2.1 bar and a frequency of 15 Hz,
“external shock wave therapy” OR “ management of trigger finger: external shock followed by focused shock wave therapy
therapeutic ultrasound” OR “ conservative wave therapy (ESWT) in three papers,13-15 (fESWT) with 500 shocks, at an energy flux
treatment “. The review included English and ultrasound therapy (UST) in one papers.7 density of 0.1 bar and a frequency of 4 Hz.
articles published up to March 2020. Articles Focused shock waves were used directly on
were selected by two reviewers (SC, PEF). Extracorporeal shock wave therapy the nodule and the maximum tenderness site,
They decided to include all papers, due and trigger finger while radial shock wave therapy was used on
to the small amount of scientific evidence in The recent interventional study of the peripheral tissues of the nodule.
literature and they excluded all those articles
not connected with human medicine, and
subsequently with rehabilitation, keeping
only articles about health conditions relevant
to rehabilitation.
They selected independently the articles
eligible for inclusion in the review in order
to reduce the risk of inter-observer bias.

ly
Any study not approved by both of the

on
reviewers was discarded (Figure 1).
Afterwards, the same reviewers extrapolated
from the articles the characteristics of the

e
sample, the devices, the trial procedures and
the outcome indexes (Table 1). us
al

Results
ci

The literature search identified 123


er

papers published in PubMed as described in


algoritm (Figure 1). We excluded n° 119
m

papers because only four papers studied


Figure 1. Study selection process.
om
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Table 1. Characteristics of the selected articles.


on

References N. N. Physical Parameters Outcomes Timing Main results


Subjects Controls therapy Shocks Frequency Flux density N. sessions
(n) (Hz) (bar) /weeks
N

Vahdatpour 19 - rESWT 1000 15 2,1 3 /1 week interval VAS T0: baseline Significant reduction of VAS
et al., 2020 QD T1: 3 weeks and QD at T1, T2 and T3
fESWT 500 4 0.1 T2: 6 weeks
T3: 18 weeks
Malliaropoulos 44s/49 - rESWT 2000 5-6 1-3 3-8 VAS T0: baseline Significant reduction of VAS
et al., 2016 RM T1: 4 weeks and better RM at T1, T2 and T3
T2: 12 weeks
T3: 1 year
Yldirim et al., 2016 20 20 ESWT vs CI 1000 15 2,1 3 /1week interval VAS T0: baseline Significant reduction of VAS,
trigger finger T1: 4 weeks QD and TFAS at T1, T2
assessment T2: 12 weeks and T3 in both groups
scale QD T3: 24 weeks
Salim et al., 2012 35 39 PT + UST vs CI - - - - VAS, T0: baseline Significant reduction
n.TFAS T1: 12 weeks of all outcomes in CI at T1.
hand grip, T2: 24 weeks PT + UST no recurrence
satisfaction, of symptoms until T2
complication and
recurrence.
QD: Quick DASH; RM: Roles and Maudsley score; TFAS: trigger finger assessment scale.

[Orthopedic Reviews 2020; 12(s1):8680] [page 91]


Review

Evaluation of pain severity, severity of reduced by 67% from baseline and at 12 dishes. Success rate was measured by
triggering, and functional impact of months, it had reduced by 91%, providing absence of pain and triggering after
triggering was carried out using the Visual excellent long-term efficacy of rESWT. completion of treatment at 3 months.
Analogue Scale (VAS), Trigger Finger Score Only one RCT was found about this Recurrence was assessed by telephone
suggested by Quinnell, Quick-Disabilities of argument; Yldirim et al.15 compared the interview at 6 months recording symptoms
the Arm, Shoulder, and Hand questionnaire efficiencies of ESWT therapy and of pain and triggering. CI treatment had
(Quick-DASH), respectively, before corticosteroid injection in the conservative higher rate of improvement in terms of pain
intervention, immediately after intervention, management of trigger finger. In this score, mean amount of triggering, hand grip
and in 6 and 18 weeks after intervention. prospective randomized clinical trial, 40 and patients’s satisfaction compared to
There were statistically significant patients with TF were randomly assigned to physiotherapy at 3 months post treatment.
differences with regard to reduction of the ESWT or injection groups. Regarding shock However, the recurrence rate was significant
pain severity, severity of triggering, and wave, each patient received 1000 shocks at for pain in the CI group but not in the PT
functional impact of triggering before an energy flux density of 2.1 bar (frequency group. Interestingly, there was no recurrence
intervention, immediately after intervention, 15 Hz) for three sessions (1-week interval of pain or triggering at all in patients who
and in 6 and 18 weeks after intervention. between the sessions). All the clinical were successfully treated with physiotherapy
Malliaropoulos et al.14 published a outcomes were assessed before treatment even 6 months post-treatment.
retrospective cohort study of 44 patients (49 and after 1, 3, and 6 months. Pain was
fingers) treated with an individually adapted measured using VAS. Because of the lack of
protocol of rESWT. According to the universally accepted instruments to measure
authors’ knowledge, this is the first study frequency of triggering (FT), the authors Discussion
conducted to assess the effectiveness of used a 0 to 10 point to evaluate this
rESWT for trigger digit. At each session, parameter according to an earlier study.16 Trigger finger, also known as stenosing
tenovaginitis, is common tenosynovitis

ly
2,000 impulses were applied to the painful This scale was also used to score the severity
area overlying the pathological flexor tendon of triggering and the functional impact of characterized by triggering or locking on

on
at a frequency of 5-6 Hz. The device triggering. Functional status was assessed flexion of the involved metacarpophalangeal
pressure varied from 1 to 3 bars depending using QuickDASH. The definition of cure joint. A variety of conservative and surgical
on the patient’s individual pain tolerance. rate was based on the Quinnell classification. treatments have been described, but none the

e
The number of weekly rESWT sessions There were statistically significant most effective treatment for trigger finger is
ranged from 3 to 8 with an average of 6±1.3,
until symptoms subsided. Primary outcome
us
differences between baseline and at 1, 3, and
6 months after treatment in terms of all
still under debate. Recently, ESWT is getting
popular as an alternative to surgery for the
measures were functional improvement and clinical (pain, severity and frequency of treatment of tendinopathies8-12 in patients
al
pain reduction at 1, 3, and 12 months post- triggering) and functional assessments inter- unrensponsive to traditional conservative
treatment compared with baseline. The Roles groups, but not between groups. treatment.
ci

and Maudsley score was used to assess The biological mechanisms by which
functional and pain severity was measured ESWT induces therapeutic effects on
er

using VAS. Recurrence of symptoms was Ultrasound therapy and trigger finger pathological tendon tissue are not
defined as a 1-year follow-up VAS score of One paper about the use of ultrasound completely elucidated, although the
m

≥2. The individualized protocols were also therapy for TF was found. This RCT 7 following ipothesis about how shockwaves
compared for the first time the effectiveness may facilitate the healing process have been
om

retrospectively analyzed in terms of the


number of sessions required and the pressure of physiotherapy (PT: 35 patients) and suggested: 8,11
used (bars). Therefore, the functional corticosteroid injection (CI: 39 patients) - promoting catabolic processes with the
treatment in the management of mild trigger disruption and removal of damaged
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improvement and mean pain reduction over


a 1-year follow up period were assessed. In fingers. matrix tissues;
on

addition, the individualised treatment Mild trigger finger is characterized by - stimulating growth factors release and
protocol was retrospectively analysed to mild crepitus, uneven finger movements and stem cell recruitment
look for correlations between pre-treatment actively correctable triggering. PT was a - producing neoangiogenesis through an
N

symptom duration, the number of rESWT multimodal rehabilitative strategy with ten increase in the angiotensin factor, that
sessions required until recovery, and the 1- sessions of wax therapy, ultrasound, gives the bloody supply to the injured
year post-treatment visual analog scale stretching muscle exercises and massage. tendon necessary to its repair
score. Outcome measurements were based on pain - stimulating the synthesis of nitric oxide
To do this, additional outcome measures relief (VAS), number of triggering events, which will suppress the progression of
were used to assess correlations, first, hand function, hand grip, patients inflammation.
between pretreatment symptom duration and satisfaction (measured as a decrease in The clinical studies of Vahdatpour et
the number of rESWT sessions required until severity of pain and triggering), al.,13 Malliaropoulos et al.14 and Yildrim at
recovery and, second, between pretreatment complication and recurrence. Number of al.15 showed the effectiveness of shock wave
symptom duration and the 1-year post- triggering events was assessed by recording therapy in reducing pain and triggering
treatment VAS score. A statistically the number of triggering events that occurred severity and in improving finger’s
significant reduction in VAS scores and in 10 active composite flexion/extension functioning.
functional improvement were found between movements and the hand grip was assessed Although multiple high-quality studies
baseline and 1, 3 and 12 months post- based on a dynamometer (JAMAR grip). have demonstrated that ESWT is safe and
treatment. Notably, in the present study, pain Hand function was assessed by restriction or effective in the treatment of various
reductions continuously increased over the pain during buttoning/unbuttoning shirt, pain tendinopathies,8-12 the parameters of the
entire 1-year follow-up period. At 1 month during opening jars/cans, ability to fully grip optimal treatment protocol for TF, haven’t
post-treatment, the mean VAS score had the hand and pain during washing clothes/ been yet established. They include shock

[page 92] [Orthopedic Reviews 2020; 12(s1):8680]


Review

wave type (focal or radial), number of injection for improving symptom severity translational gliding. Finally, massaging can
shocks, energy flux density, frequency, and functional status in patients with a ‘soften’ or remodel tendons reducing tissue
pressure, number of sessions. classification of grade 2 according to the bulk at the pulleys.
About shock waves generation, Quinnell classification. The study7 concursed with studies about
Malliaropoulos et al.14 choose to use radial Also duration of pretreatment symptoms other tendinopathies with a high success rate,
shockwaves because they allow the could influence session’s number: shorter- measured as the absence of pain and
treatment of a larger tissue volume compared term cases required fewer sessions then triggering, of corticosteroid compared to
to the focal one; in fact the pathological patients with a longer history of symptoms.14 physiotherapy at 3 months after treatment.
hypertrophyc area in TF is wider than those Results showed that ESWT is an The corticosteroid group also shows a
involved in insertional tendinopathies, for effective and safe therapy for the significant increase in grip strength
which focal ESWT is usually used. rESWT conservative management of TF. It seemed compared to physiotherapy.
is also less painful than focused ESWT. This to reduce pain and trigger severity and Therapeutic ultrasound was less
makes local anesthetic unnecessary and improves functional level. No side effects effective in reducing pain and in improving
potentially improves treatment outcome as were reported. Notably, excellent long-term function immediately post treatment
concomitant local anesthesia showed to efficacy of rESWT was found: pain compared to corticosteroid injection, but
reduce ESWT efficacy. reductions continuously increased over interestingly have proven to be useful to
About the total number of shocks of each entire 1-year follow-up period, and at 1- prevent the recurrence of symptoms (pain or
session, it ranges from 500 to 2000 shocks. month post-treatment, the mean VAS score triggering) after 3 and 6 months post-
Two studies13,14 performed 1000 shocks had reduced by 67% from baseline and at 12 treatment. In fact there was no recurrence of
instead, and one14 used a number of 2000 months, it had reduced by 91%.14 pain or triggering in the UST group.
shocks. Only in Vahdatpour et al study 13 has In In the RCT of Yildrim at al.15 about Both treatments are safe as there were no
been specified the number of impulses ESWT versus CI, both treatments was found complications seen. So ultrasound therapy
could be used for patients who dislike or are

ly
related to the type of device: 1000 shocks for to relieve symptoms, but CI was more
rESWT and 500 shocks for fEWST. effective than ESWT. However, ESWT is uncomfortable with needles and injections.

on
The flux density ranged from 0,1 bar to recommend for patients who reject
Limitations of the study
3 bar, with two studies using 2,1 bar, corticosteroid injections because of their
Some potential limitations of our study
considering previous studies using EWST in potential complications, or allergic patients
should be mentioned. The literature search

e
tendinopathies. For the fESWT a flux to local anaesthetics, as well as in patients
us was done screening the papers listed in only
density of 0,1 bar was setted. About with an intense and persistent fear of
three databases and only English articles
frequency, the most used value was of 15 Hz injections. Even though no deleterious effect
were included. Moreover, studies are few
(13,15); also frequency of 5-6 Hz 14 and 4 Hz of corticosteroid injection was seen in the
and heterogeneous, with poor sample size
al
for fESWT were found. study analyzed,15 there have been previous
and with different outcome mesaures. So
Vahdatpour et al. 13 performed sessions studies reporting dermal or subcutaneous
ci

even if the results suggest the effectiveness


composed by one phase of radial ESWT atrophy, transient hyperglycaemia,
of ESWT and UST for TF, future studies are
followed by a second phase of focal ESWT. hypopigmentation of the skin, infection, and
er

necessary to understand the characteristics


In Yildrim study 15 shock wave’s type wasn’t rupture of the flexor digitorum profundus
of the optimal treatment protocol for trigger
indicated. tendon in rare cases of CI.17
m

finger.
It has been demonstrated that pressure Only one paper was found about the
om

and number of sessions are inversely effectiveness of UST for TF,7 that for the first
proportional: the higher the pressure, the time compared the success rate of
greater the treatment effects; thus, less physiotherapy, including therapeutic
Conclusions
-c

sessions are required, the lower the pressure, ultrasound, or corticosteroid injection in
the more sessions are required to have a managing trigger finger. This narrative review provides a
on

therapeutic effect. But ESWT at high In patients with TF the tendon becomes synthesis of the scientific literature available
pressure is very painful, so the right extensile, undergoes plastic deformation and about physical therapies for trigger finger.
compromise between patient tolerability and passes more easily through the stenotic A1
N

Results showed that ESWT is an effective


therapeutic results must be found. Compared pulley. and safe therapy for the conservative
to other tendinopathies treated with rESWT, Therapeutic heat includes superficial management of TF. It seems to reduce pain
the finger is a rather painful area to treat. (depths of 2-3cm) and deep (up to 5cm) and trigger severity and to improve
This might explain why comparatively low modalities. Superficial modalities include functional level and quality of life. UST has
pressures have to be used. hot packs, hot wax and paraffin baths whilst proven to be useful to prevent the recurrence
Currently, there are no standardized deep modalities include ultrasound and of TF symptoms. However further studies
guidelines for the number of ESWT sessions diathermy. Heat increases blood flow and are necessary to clarify the efficacy of
required, although studies have suggested extensibility of collagen tissue assisting in physical therapies in the conservative
that multiple applications provide superior resolution of edema. Additionally, heat also treatment of TF. In addiction the best
long-term results compared to a single decreases joint stiffness and pain. A treatment energy set-up and protocol for TF
application. Clinical trials analyzed in this combination of heat and stretching is even are still left to be found.
review showed a total number of 3 sessions more effective as it capitalizes on the
13,15 and a range of 3-8 sessions, suggesting extensibility of collagen producing plastic
individualized treatment protocols according deformation, e.g. bandage wraps of a joint in
to each patient’s tolerance and response to flexion prior to application of hot packs.18 References
treatment. 14 Data from Yildrim et.al 15 RCT Additionally, joint mobilization helps
showed that 3 sessions of ESWT treatment increase joint and soft tissue mobility via a 1. Huisstede BM, Hoogvliet P, Coert JH,
could be as effective as a corticosteroid slow, passive therapeutic traction and Fridén J. Multidisciplinary consensus

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results from the european Stamenkovic D, Pavlovic I Radial Med 2020;11:85-91.
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2014;94:1421-33. treatment of shoulder calcific tendinitis. Radial extracorporeal shockwave
2. Farnebo S, Chang J. Practical Coll Antropol. 2011. therapy for the treatment of finger
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3. Frontera WR, Silver JK, Rizzo TD. epicondylitis. J Bone Joint Surg Am
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7. Salim N, Abdullah S, Sapuan J, Haflah functional measures. Foot Ankle Int Acosta M, et al. Effect of superficial
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