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UNITUXIN ASSESSMENT

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PATIENT EDUCATION

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Report severe or worsening pain, numbness,

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tingling, weakness, or burning in your hands
DINUTUXIMAB (DI-NOO-TUX-I-MAB) or feet, or if you have problems with walking
Drug class: Monoclonal antibodies or daily activities.

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Action : Acts as a glycolipid Monitor for signs and symptoms of hemolytic
Some side effects may occur during the
uremic syndrome (fatigue, dizziness, fainting,

disialoganglioside (GD2)-binding
monoclonal antibody, that binds to specific
cells in the CNS and peripheral nerves.
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injection or up to 24 hours afterward. Report
pallor, swelling, decreased urine)
right away if you feel dizzy or light-headed, or
if you have a skin rash, chest pain, trouble Monitor electrolytes daily. May cause

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breathing, or swelling in the face. decrease in potassium, decrease in sodium,

Unituxin is a cancer medicine that interferes co rc Do not use Unituxin if you are pregnant. It
and decrease in calcium.
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with the growth and spread of cancer cells could harm the unborn baby. Use effective Assess pain
in the body birth control to prevent pregnancy while you • Assess for signs and symptoms for lower leg
and hand weakness and inability to walk, lack
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are using Unituxin and for at least 2 months
Unituxin is used in combination with other after your treatment ends. of bladder
medicines to treat neuroblastoma (a type of
brain tumor) in children.
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Who can use this drug INTERACTIONS

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Unituxin is for the treatment of
children with high risk •

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DRUG INTERACTION
neuroblastoma which is a solid tumor
outside the brain. Nursing

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over-the-counter medicines, vitamins,

Management
DOSE INFORMATION herbal products, and radiation therapy
The dose is given in an IV of 17.5

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mg for 4 days in a row, for up to 5
sets

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assess for urine in the bladder

SIDE EFFECT Monitor for signs and symptoms of infection. If

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severe infection or bacteria in the blood, stop
Infections, infusion reaction, low blood
Bub co rc pressure, low potassium, vomiting, fever,
pain, and capillary leak syndrome
until infection is taking care of
Assess for signs and symptoms of reverse
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for posterior leukoencephalopathy syndrome
(severe headache, high blood pressure, eye
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problem, sleepiness, seizures). stop if

• PATIENT CONSIDERATION symptoms occur
 May cause unborn baby harm, discontinue
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breast feeding, and female patient with

reproductive potential effective birth control is
required.
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