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ABW/IBW:
Sensitivity Requirement (mg) x 100% / acceptable error Underweight ≤ 89%
(%) Normal 90-120%
Overweight 120-150%
Percentage Error (%)= Obese 150-200%
Error x 100% / Quantity desired
XObese≥200
Drug Moiety=
Cal: BEE;
Drug moiety weight/ Drug compound weight = moiety
Men= 66.5 + [13.75 x W (kg)] + [5 x H (cm)] - [6.78 x age]
M.W. / compound M.W.
Women= 655.1 + [9.56 x W (kg)] + [1.85 x H 9cm)] - [4.68 x
Milliosmole (mOsmol/L) = age]
[Concentration (mg/L) x Number of particles] / M.W.
Daily Caloric Expenditure (DCE) = Activity factor x BEE
Plasma Osmolarity (mOsmol/kg) =
Dextrose:
2[plasma Na] + [BUN]/2.8 + [Glc]/18
Parenteral= 3.4 kcal/g
Milliequivalent (mEq) = Weight (mg) x Valance / M.W. Enteral= 4 kcal/g
E-value = Lipid:
[NaCl M.W. /NaCl i-value] x [substance i-value/substance 20-40% of total daily calories
M.W.] 10%: 11kcal/g (1.1kcal/ml) 20-30%: 10kcal/g (2-
3kcal/ml)
Amt of Water Needed (ml)=
[Drug weight(g) x Drug E-value]/0.009 Fiber: (14g/1000kcal)
Men: 30-38 g
Freezing Point:
Women: 21-25 g
{Drug concentration (g/L) / 1.86 x i-
value} = {Substance concentration (g/L) / X } Fluid: 30 ml/kg
or
CrCl:
{Drug M.W. (g/L) / 1.86 x I-
1. Jelliffe: [98 - 0.8 (age -20)]/ SrCr {for women x 0.9}
value] = {Substance (g/L) / 0.52 }
2. Cockcroft: (140 – age) x W (kg) / 72 x SrCr {x0.85}
Dilution: C1 x Q1= C2 x Q2 Adjusted CrCl = BSA x CrCl / 1.73
BSA = Second root of [H (cm) x W (kg) /3600] Adjusted body weight= IBW + 0.4 (ABW – IBW)
Patient specific dosing (mg) = Loading dose (LD) = IBW (kg or lbs) x Drug dose (per kg or
Usual dose (mg/m2) / BSA (m2) lbs)
BSA (m2) x adult dose (mg) / 1.73 (m2)
Maintenance Dose (MD)=
Infusion Time = Norm: IBW(kg or lbs) x Drug dose(per kg or lbs)per dosing
Volume of infusion (ml) / Flow rate (ml/h or ml/min) interval
Renal imp.: CrCl x Normal MD / 100 (ml/min)
Rate of Flow (drops/min) =
[Volume infused (ml) x Drip set (drops/ml)] / Time (min) Total cholesterol = LDL + HDL + 0.2 TG (mg/dL)
Infusion Rate (ml/h)=
[Weight (kg) x Dose (units/kg/hour)] / Infusion drug
concentration (units/ml)
IBW :
Men= 110 + (5 x inches over 5 ft)
Women= 100 + (5 x inches over 5 ft)