DRUG STUDY

Date Generic Brand Classificatio Indication Mechanism Dosage & Time Adverse Nursing
Name Name n of Action Frequency Given Reaction Consideration
03-11- Celecoxi Celebre Therapeutic: Relief of Inhibits the CNS:  Monitor rashes or
21 b x antirheumati signs and enzyme dizziness, other skin
cs, symptoms COX-2. headache, reactions (hives,
nonsteroidal of This insomnia. itching, dermatitis,
anti- osteoarthr enzyme is CV: exfoliation). Notify
inflammator itis, required for edema. GI: physician
y agents rheumatoi the GI immediately
d arthritis, synthesis BLEEDING because certain
Pharmacolo ankylosin of , abdominal skin reactions
gic: COX-2 g prostaglan pain, may indicate
inhibitors spondyliti dins. Has diarrhea, serious
s, and analgesic, dyspepsia, hypersensitivity
juvenile anti- flatulence, reactions
rheumatoi inflammato nausea. (Stevens-Johnson
d arthritis. ry, and Derm: syndrome, toxic
Reduction antipyretic EXFOLIATI epidermal
of the properties. VE necrolysis).
number of Therapeuti DERMATIT  Watch for signs of
adenomat c Effects: IS, GI bleeding,
ous Decreased STEVENS- including
colorectal pain and JOHNSON abdominal pain,
polyps in inflammatio SYNDROM vomiting blood,
familial n caused E, TOXIC blood in stools, or
adenomat by arthritis EPIDERMA black, tarry stools.
ous or L Although
polyposis spondylitis. NECROLY celecoxib may
(FAP), as Decreased SIS, rash. produce fewer GI
an adjunct number of side effects than
to usual colorectal other NSAIDs,
care polyps. some patients
(endosco Decreased may still
pic pain. experience GI
surveillan bleeding and
ce, other gastric
surgery). problems
Managem (diarrhea,
ent of nausea,
acute flatulence,
pain, heartburn).
including Report these
primary signs to the
dysmenor physician
rhea. immediately.
 Continually
monitor for signs
of MI (sudden
chest pain, pain
radiating into the
arm or jaw,
shortness of
breath, dizziness,
sweating, anxiety,
nausea) and
stroke (sudden
severe headache,
confusion,
nausea, vomiting,
paralysis,
numbness,
speech problems,
visual
disturbances).
Although rare,
celecoxib has
been associated
with coronary and
cerebral
thrombosis. seek
immediate
medical
assistance if
patient develops
these signs.