SEPALA, KIN NARITA C.

2019300097

BSN 2B

Drug Study: ACETAMINOPHEN

Complete the drug study of the ordered drug below. You may use a drug handbook such as Lippincott’s Nursing Drug Guide as your reference.

Dr. Garcia ordered the drug: Acetaminophen 365mg p.o q4h

Patient HRN: 1234567 Age/Gender: 56/F Rm: 102
Admitting Diagnosis: Rheumatoid Arthritis Birthday: 6/24/1964

Drug Mechanism of Action Indications or Purpose Contraindications Side Effects  Adverse Reactions Nursing Responsibilities 

 Acts directly on the  Acetaminophen is  It is contraindicated  Nausea  Hematologic:  Inform patient of potential
Generic Name: hypothalamus to indicated for the in the presence of thrombocytopenia, adverse reactions.
cause vasodilation treatment of pain and allergy to  Stomach pain hemolytic anemia,
and sweating, which fever associated with acetaminophen neutropenia,  Do not exceed the
will reduce fever; a variety of conditions, because of the risk  Loss of appetite leukopenia, recommended dosage.
Acetaminophen mechanism of action including infl uenza; of hypersensitivity pancytopenia
as an analgesic is not for the prophylaxis of reactions.  Itching  Give drug with food if GI
understood. children receiving  Hepatic: jaundice, upset occurs.
diphtheria– pertussis–  It should be used  Rash hepatotoxicity
tetanus immunizations cautiously in  Treatment of overdose:
(aspirin may mask pregnancy or  Metabolic: Monitor serum levels
 Headache
Reye syndrome in lactation because of hypoglycemic coma regularly, N-acetylcysteine
Brand Name: children); and for the the potential for should be available as a
relief of  Dark urine,
adverse effects on  Skin: rash, urticaria specific antidote; basic life
musculoskeletal pain the fetus or baby and support measures may be
associated with in hepatic  Clay-colored
stools  Other: hypersensitivity necessary.
Tylenol arthritis dysfunction or reactions (such as
chronic alcoholism
  Mild to moderate pain because of  Jaundice fever)
caused by associated toxic (yellowing of skin
Classification: headache,muscle effects on the liver. or eyes).
ache, backache, minor
arthritis, common cold,
toothache, or
Analgesic, menstrual cramps or
fever
Antipyretic

Dose, Route & Timing:

365 mg p.o q4h

Reference/s:

Focus on Nursing Pharmacology

Nursing-Laboratory-and-Diagnostic-Tests-Demystified

https://www.rxlist.com/tylenol-side-effects-drug-center.htm

https://www.rnpedia.com/nursing-notes/pharmacology-drug-study-notes/acetaminophen-n-acetyl-p-aminophenol/
Drug Study: gold sodium thiomalate (Aurolate)

Complete the drug study of the ordered drug below. You may use a drug handbook such as Lippincott’s Nursing Drug Guide as your reference.

Dr. Garcia ordered the drug: gold sodium thiomalate (Aurolate) 10 mg IM now
Patient HRN: 1234567 Age/Gender: 30/F Rm: 102
Admitting Diagnosis: Rheumatoid Arthritis Birthday: 10/24/1990

Drug Mechanism of Action Indications or Purpose Contraindications Side Effects  Adverse Reactions Nursing Responsibilities 

 Injected drug for early  Hypersensitivity to  CNS: confusion,

Generic Name:  Inhibits inflammatory treatment of any component of  Flushing, hallucinations,  Periodically assess
process. Modifies rheumatic disorders this product. dizziness, seizures. impairments (pain, range of
immune response headache, nausea, motion), functional ability,
(immunomodulating  Progressive  Severe toxicity vomiting,  CV: bradycardia, and disability to help
Gold Sodium properties). rheumatoid arthritis resulting from weakness, and hypotension. document whether
Thiomalate resistant to previous exposure sweating may antirheumatic drug therapy is
 It is thought to be conventional therapy. to gold or other occur soon after  EENT: corneal gold successful
effective against heavy metals. the injection. deposition, corneal
rheumatoid arthritis by ulcers.  Assess any breathing
Brand Name: altering the immune  Severe  Increased joint problems or signs of
system to reduce debilitation. pain may occur 1-2  GI: metallic taste, pneumonitis such as dry
inflammation. Although days after your stomatitis, diarrhea, cough, wheezing, rales,
the exact mechanism  Systemic lupus injection. If any of anorexia, abdominal chest pain, shortness of
remains unknown, erythematosus. these effects cramps, nausea, breath, and difficult or
Aurolate these compounds have persist or worsen, labored breathing. Monitor
vomiting, ulcerative
reduced serum levels tell your doctor or enterocolitis. pulse oximetry and perform
of immunoglobulins and pharmacist pulmonary function tests to
rheumatoid factors in promptly.  GU: proteinuria, quantify suspected changes
Classification: patients with arthritis. in ventilation and respiratory
nephrotic
syndrome,nephritis, function.
acute tubular
necrosis, hematuria,  Assess heart rate and ECG,
acute renal failure. especially during exercise.
 Antarthritic  Hematologic: Report bradycardia or
thrombocytopenia symptoms of arrhythmias,
(with or without including chest discomfort,
purpura), aplastic shortness of breath, fainting,
anemia, and fatigue/weakness.
agranulocytosis,
Dose, Route & Timing: leukopenia,  Assess dizziness and
eosinophilia, syncope that might affect
anemia. gait, balance, and other
functional activities. Report
10 mg IM now  Hepatic: hepatitis, balance problems and
jaundice. functional limitations to the
physician, and caution the
 Skin: diaphoresis, patient and family/caregivers
photosensitivity, to guard against falls and
rash, dermatitis, trauma.
erythema, exfoliative
dermatitis.

 Other: anaphylaxis,
angioedema.

Reference/s:

https://www.webmd.com/drugs/2/drug-75303/gold-sodium-thiomalate-injection/details

https://www.rxlist.com/myochrysine-drug.htm#clinpharm

https://www.glowm.com/resources/glowm/cd/pages/drugs/g016.html
Drug Study: hepatitis B vaccine

Complete the drug study of the ordered drug below. You may use a drug handbook such as Lippincott’s Nursing Drug Guide as your reference.

Dr. Garcia ordered the drug: hepatitis B vaccine 0.5–1 mL IM, followed by 0.5–1 mL IM at 1 and 6 mo

Drug Mechanism of Action Indications or Purpose Contraindications Side Effects  Adverse Reactions Nursing Responsibilities 

 Immunization
Generic Name:  Active immunization with against hepatitis B
hepatitis B vaccine
stimulates the immune
system to produce anti-
Hepatitis B Vaccine HBs without exposing
the patient to the risks of
active infection. Infection
with hepatitis D can
occur only with
Brand Name:
concurrent hepatitis B
infection, so vaccination
with recombinant
hepatitis B vaccine
Energix B, provides protection
Recombivax HB against hepatitis D as
well.
 ENGERIX®-B induces
Classification: specific humoral
antibodies against
HBsAg (anti-HBs
antibodies). It is
Vaccine generally accepted that
an anti-HBs titre greater
than 10 IU/L correlates
with protection against
hepatitis B virus
infection. More than
Dose, Route & Timing: 90% of healthy adults,
children and neonates
developed protective
 Headache.
 Yeast  Local reactions  Nurses should refer to
infections in hypersensitivity  Rash. manufacturer’s summary
susceptible people  Fever of product characteristics
and in infants born  Neonates,  Fatigue. and to appropriate local
to mothers with premature neonates  Headache guidelines.
hepatitis B  Cold or flu-like
 Anticoagulant symptoms.  Vertigo
therapy,
coagulopathy,  Fever (pyrexia).  Arthralgia
hemophilia,
intravenous  Pins and needles  Malaise
administration, (paraesthesia).
subcutaneous
 Arthritis and
administration,  Dizziness. erythema
thrombocytopenia,
vitamin K deficiency  Pain in the joints  Erythma multiforme
(arthralgia).
 Cardiac disease,
 Guillane-Barre
fever, infection  -Pain in the
syndrome
muscles
 Chemotherapy, (myalgia).
 Stevens Johnson
human
syndrome
immunodeficiency  Itching (pruritis).
virus (HIV) infection,
immunosuppression  Seizures
 Soreness at
injection site.  Hypotension
 Dialysis, renal
disease, renal failure
 Allergic reactions  Alopecia
such as lips
 Pregnancy swelling, tongue
 anti-HBs titres one  Breast-feeding and throat  Autoimmune
month after completing (angioedema) or disorders
0.5–1 mL IM, a primary vaccination  Latex narrowing of the
followed by 0.5–1 mL schedule of ENGERIX®- hypersensitivity airways
IM at 1 and 6 mo B (hepatitis B vaccine (bronchospasm).
(recombinant)).

Reference/s:

https://www.pdr.net/drug-summary/Engerix-B-hepatitis-B-vaccine--recombinant--

https://www.pediatriconcall.com/drugs/hepatitis-b-vaccine/635

https://www.nursingtimes.net/clinical-archive/medicine-management/hepatitis-b-vaccine-08-10-2004/