Chromosomal Basis of Inheritance MCQ (Multiple Choice Questions and

Answers)
Q1. Term chromosome was coined by

Hoffmeister
Sutton
Boveri
Waldeyer
Q2. Chromosomes were first seen by

Hoffmeister
Waldeyer
Strasburger
Fleming
Answer:1

Q3. Chromosomes found in the salivary gland of drosophila is

Lampbrush
Polytene
Supernumerary
B-chromosomes.
Answer:2

Q4. Giant chromosome with a number of chromonemeta is

Lampbrush chromosome
Hetrochromosome
Supernumerary chromosome
Polytene chromosome
Answer:4

Q5. Lampbrush chromosomes occur in

Salivary glands
Lymph gland
Cancer cells
Oocytes
Answer:4

Q6. Chromosome ends are called

Satellites
Tellomeres
Centromeres
Kinetochore
Answer:2

Q7. Chromatid is

One-half of chromosome
Haploid chromosome
Complete chromosome
Duplicate chromosome
Answer:1

Q8. Centromere is that part of chromosome where

Nucleoli are formed

Crossing over takes place
Chromatids are attached
Nicking occurs
Answer:3

Q9. A chromosome with sub-terminal centromere is

Acentric
Acrocentric
Metacentric
Telocentric
Answer:2

Q10. A chromosome with centromere near the middle is

Metacentric
Sybmetacentric
Acrocentric
Telocentric
Answer:2

Q11. Puffs or balbiani rings in salivary gland chromosome are site of

DAN replication
DNA duplication
RNA synthesis
Protein synthesis
Answer:2

Q12. Chromosome theory of inheritance was proposed by

Sutton (1902)
Boveri (1902)
Both 1 and 2
Correns(1909)
Answer:3

Q13. More than 200 chromosomes occur in

Chicken
Dog
Amoeba
Gorilla
Answer:3

Q14. Drosophila has four homologous pairs of chromosome. What is the

number of linkage group in this animal?

4
2
8.
Uncertain
Answer:4

Q15. Gene for colour blindness in man is located on

X-chromosome only
Y-chromosome only
Either X-chromosome or Y-chromosome
Both X and Y chromosome
Answer:1

Q16. A colour blind daughter may be born if the

Father is normal and mother is colour blind

Father is colour blind and mother is normal
Father is normal and mother is carrier
Father is colour blind and mother is carrier
Answer:4

Q17. A somatic cell in human male contains

No gene on sex chromosome

Only one sex linked gene for each character
Two genes for every sex linked character
Genes on only on sex chromosomes
Answer;2

Q18. A normal woman is married to a colour blind man. The children are
expected to be

All normal
50% sons are colour blind
All daughters are normal but carrier whereas all sons are normal
phenotypically as well as genotypically
50% daughters are colour blind
Answer:3

Q19. Which of the following dieses is sex linked?

Colour blindness
Malignancy
Hepatitis
Lukemia
Answer:1

Q20. The genes for the eye colour and size of the wing in drosophila are
located on the same chromosome. They can be separated by
Non-disjunction
Crossing over
Hybridisation
Not be separated at any stage
Answer:2

Q21. A colour blind son is born to a normal parents. It shows that

The father was hetrozygous for colour blindness

The mother was hetrozygous for colour blindness
The mother was genotypically homozygous
Both parents carried a recessive gene for the disorder
Answer:3

Q22. Chromosomal constitution in human female can be best written as

46
44+2
44A+XX
44A+XY
Answer:3

Q23. The sex linked characters are those

Which are related to sexual physiology

The genes of which are present on the sex chromosomes
Which appear either in male and female
Which are controlled by sex hormones
Answer:2
Q24. Chromosomes other than sex chromosomes are called

Autosomes
Heterosomes
Karyosomes
None of the above
Answer:1

Q25. If the crossing over had occurred at two strand stage in neurospora the
ascospores would be arranged in

1-1 position
2-2 position
4-4 position
None of these
Answer:3

Q26. Complete linkage is found in

Birds
Snakes
Female drosophila
Male drosophila
Answer:4

Q27. In most of the higher unisexual animals there is one chromosomal pair
which is not identical in two sexes , these are called

Non homologous chromosomes

None identical chromosomes
Non compatible chromosomes
Sex chromosomes
Answer:4

Q28. The to diverse disciplines of cytology and genetics were correlated by

Muller
Morgan
Bridges
Tschermak
Answer:3

Q29. Linkage group is defined as

All the linked genes of a chromosomal pair

Different groups of genes present on different chromosomes
All the genes located on the same chromosome
None of the above
Answer:1

Q30. Linkage in drosophila was reported by

Mendel
Correns
Morgan
None of these
Answer:3

Q31. Phenomenon which works opposite to the linkage is

Independent assortment
Crossing over
Segregation
Mutation
Answer:2

Q32. When two genes are situated very close to one another at a
chromosome

The percentage of crossing over between them is very high

Hardly any cross overs are produced
No crossing over can take place
Only double Cross overs can occur between them
Answer:2

Q33. Greater is the distance between the two genes on chromosome

Greater is the linkage strength

Lesser is the linkage strength
Linkage strength remains unchanged
There is no relationship between the two
Answer:2

Q34. Crossing over occurs at

Single strand stage of chromosomes during prophase

2 strand stage during zygotene
Four strand stage of Pachytene
Metaphase II of meiosis
Answer:3

Q35. The term coupling and repulsion signify the same phenomenon which
is termed
Synapsis
Disjunction
Linkage
Non disjunction
Answer:3

Q36. The linked characters would always inherit together till they are

Delinked due to segregation

Mask by dominance
Mutated
Separated due to crossing over
Answer:4

Q37. White eyed and long wind male drosophila was crossed to a vestigial
winged red eyed female. The two characters are linked in this animal when
a female F1 was just crossed the F2 generation produced

Mostly white eyed with long wings

Mostly red eyed with vestigial wings
Mostly white eyed with long wings and red eyed with vestigial wings
All white eyed and vestigial winged
Answer:3

Q38. A haemophilic man marries a normal women, what is the probability of

the disease in the grandchildren in case the daughter marries a normal man

All grandsons would be haemophilic and granddaughters normal

50% of grandsons are hemophilic other grandchildren are normal
Only granddaughters would be haemophilic
All grandchildren would be haemopgilic
Answer:2
Q39. Colour blind man marries abnormal woman whose father was
colorblind what percentage of children is expected to be colour blind

25%
50%
75%
100%
Answer:2

Q40. Mendel did not get any linkage in his experiments on pea , one of the
reasons was that

He did not keep an exact record

There is no linkage in pea
He did not have means to detect linkage
All the 7 characters selected by him were present on different chromosomes
or showed 50% crossovers
Answer:4

Q41. The genes of different traits located on different loci on the same
chromosome are

Alleles
Linked
Pleiomorphic
Mutated
Answer:2

Q42. In four o’clock plant normal leaves A and veriegated leaves B occur in
different plants, if B male is crossed with A female the hybrid has normal
lives but when B female is crossed with A male the hybrid has veriegated
leaves , it is a case of
Mutation
Cytoplasmic inheritance
Complementary genes
Supplementary genes
Answer:2

Q43. Crossing over occurs between

Two non sister chromatids of a homologous pair of chromosomes

Two chromatids of any chromosomes
Two chromatids of same chromosome
All the foregoing
Answer:1

Q44. Neurospora crassa is widely used in genetic studies because of all the
following except one

It is a haploid plant and mutations can be easily detected

It can be easily cultured
Life cycle short
Sports are not affected by mutagenesis
Answer:4

Q45. The frequency of crossing over would be higher if

Two genes are located closely

Two genes are far apart on a chromosome
Two genes are not located on the same chromosome
None of the above
Answer:2

Q46. Mendelian recombinations are due to

Mutation
Linkage
Crossing over
Independent assortment of characters
Answer:4

Q47. The blue green algae and bacteria contain

One linkage group

Two linkage groups
Three linkage groups
None of the above
Answer:1

Q48. Which one of the following character in man is controlled by a

recessive gene?

Colour blindness
Woolly hair
Brachydactyly
Curly hairs
Answer:1