Gist of some studies conducted on effects of Gamma-Oryzanol in reducing Obesity
S. No. Title / Author / Journal Year
1 Gamma Oryzanol Treats Obesity- 2018
Induced Kidney Injuries by Modulating
the Adiponectin Receptor 2/PPAR-α
Axis/ Artur Junio Togneri Ferron,
Fabiana Kurokawa Hasimoto, Pedro
Henrique Rizzi Alves, Jéssica Leite
Garcia, Klinsmann Carolo dos Santos ,
Fernando Moreto, Vanessa dos Santos
Silva , Ana Lúcia A. Ferreira, Igor
Otávio Minatel, and Camila Renata
Corrêa / Hindawi Oxidative Medicine
and Cellular Longevity
2 Impact of brown rice-specific γ-oryzanol 2017
on epigenetic modulation of dopamine
D2 receptors in brain striatum in high-fat-
diet-induced obesity in mice / Chisayo
Kozuka, Tadashi Kaname, Chigusa
Shimizu-Okabe, Chitoshi Takayama,
Masato Tsutsui, Masayuki Matsushita,
Keiko Abe, Hiroaki Masuzaki /
Diabetologia
3 Effects of ferulic acid and γ-oryzanol on 2015
high-fat and high-fructose diet-induced
metabolic syndrome in rats / Ou Wang,
Jia Liu, Qian Cheng, Xiaoxuan Guo,
Yong Wang, Liang Zhao, Feng Zhou,
Baoping Ji / Plos One
4 Supplementation of Conjugated Linoleic 2008
Acid with γ-Oryzanol for 12 Weeks
Effectively Reduces Body Fat in Healthy
Overweight Korean Women / Jung Hee
Kim, Ok Hyun Kim, Yeong Lae Ha and
Jeong Ok Kim / Journal of Food Science
and Nutrition
Type of study Findings Link
in-vivo The results of this study confirm that Gamma http://downloads.hinda
Oryzanol is able to modulate PPAR-α expression, wi.com/journals/omcl/
inflammation and oxidative stress pathways 2018/1278392.pdf
improving obesity-induced renal disease.
in-vivo This study demostrated that Gamma Oryzanol https://pubmed.ncbi.nl
ameliorates high fat diet-induced DNA m.nih.gov/28528402/
hypermethlation of the promoter region of dopaine
D2 receptor in the striatum, a pivotal regulator of
the brain reward system, resulting in hedonic
overeating. This study highlights Gamma Oryzanol
as a promising antiobesity substance with the
distinct property of being a novel epigenetic
modulator.
in-vivo This study investigates the effects of Gamma https://pubmed.ncbi.nl
Oryzanol on alleviating high-fat and high-fructose m.nih.gov/25646799/
diet (HFFD) -induced metabolic syndrome
parameters. From the findings of this study it was
concluded that Gamma Oryzanol is effective in
alleviating HFFD-induced obesity, hyperlipidemia,
hyperglycemia, hepatic injury and insulin
resistance. Thus Gamma Oryzanol could be used as
a dietary supplement to alleviate the deleterious
effects of HFFD.
Human The findings of this study suggest that Gamma https://www.koreascie
Intervention Oryzanol could be a useful ingredient to mix with nce.or.kr/article/JAKO
conjugated linolenic acid for the reduction of 200828955288431.do
human body fat.