Professional Documents
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RATIONALE
In every happy occasions there are always people behind the scenes and those people are
the one who washes the dishes after every their done celebrating and eating, and their most
Dishwashing liquids are detergents that are used to assist in hand washing as well as
machine washing of glasses, plates, cutlery and cooking utensils. These detergent products are
usually a high-foaming mixture of surfactants with low skin irritation. Regardless of brand, few
characteristics and features are vital in a hand dishwashing liquid that include - lasting suds,
mildness to hands, superior cleaning performance, safety for dishes and other washables, storage
formulating and designing a dishwashing liquid to meet this criterion, manufacturers typically
PROCEDURE:
Sodium Chloride
UNIVERSITY OF SOUTHERN PHILIPPINES FOUNDATION
SALINAS DRIVE, LAHUG, CEBU CITY
Description:Sodium Chloride contains not less than 99.0 percent and not more than 100.5
percent of NaCl, calculated on the dried basis.
Packaging and storage: Preserve in well-closed containers.
Labeling: Where Sodium Chloride is intended for use in the manufacture of injectable dosage
forms, peritoneal dialysis solutions, hemodialysis solutions, or hemofiltration solutions, it is so
labeled. Where Sodium Chloride must be subjected to further processing during the preparation
of injectable dosage forms to ensure acceptable levels of Bacterial endotoxins, it is so labeled.
Where Sodium Chloride is sterile, it is so labeled.
Appearance of solution: Dissolve 20.0 g of Sodium Chloride in carbon dioxidefree water, and
dilute with the same solvent to 100.0 mL. This solution is clear and colorless.
Identification: It responds to the tests for Sodium 191 and for Chloride.
Chloride: Dissolve about 3 mg of Sodium Chloride in 2 mL of water. Acidify with diluted nitric
acid and add 0.4 mL of silver nitrate TS. Shake, and allow to stand. A curdled, white precipitate
is formed. Centrifuge, wash the precipitate with three 1mL portions of water, and discard the
washings. Carry out this operation rapidly in subdued light, disregarding the fact that the
supernatant may not become perfectly clear. Suspend the precipitate in 2 mL of water and add
1.5 mL of 10 N ammonium hydroxide. The precipitate dissolves easily with the possible
exception of a few large particles, which dissolve more slowly.
Bacterial endotoxins 85: The level of Bacterial endotoxins are such that the requirement under
the relevant dosage form monograph(s) in which Sodium Chloride is used can be met. Where the
label states that Sodium Chloride must be subjected to further processing during the preparation
of injectable dosage forms, the level of Bacterial endotoxins are such that the requirement under
the relevant dosage form monograph(s) in which Sodium Chloride is used can be met.
PARAMETERS SPECIFICATIONS
1. Organoleptic Evaluation
1.1 Color Blue
1.2 Odor/Flavor Downy Scent
1.3 Appearance Clear
1.4 Form Liquid
2. Physical Properties
UNIVERSITY OF SOUTHERN PHILIPPINES FOUNDATION
SALINAS DRIVE, LAHUG, CEBU CITY
2.1 pH 7-8
2.2 Specific gravity 1.0
2.3 Viscosity high
3. Chemical Properties
3.1 Assay: Each 350 mL of Dishwashing Liquid contains
Sodium Lauryl Ether Sulfate 1.083%
Degradation product
4. Microbiological Testing
4.1 Standard Plate Count not more than 100 cfu
4.2 Salmonella Count 0 cfu
4.3 Coliform Count 0 cfu
4.4 Molds and Yeast Count not more than 10 cfu
CERTIFICATE OF ANALYSIS
1. Organoleptic Evaluation
1.1 Color Orange Orange
1.2 Odor Orange Scent Orange Scent
1.3 Appearance Clear Clear
1.4 Form Liquid Liquid
2. Physical Properties
UNIVERSITY OF SOUTHERN PHILIPPINES FOUNDATION
SALINAS DRIVE, LAHUG, CEBU CITY
2.1 pH 7-8 8
2.2 Specific gravity 1.1-1.3 1.2
2.3 Viscosity 200-500 cps 300 cps
2.4 Deliverable volume 95-100% 98%
3. Chemical Properties
3.1 Assay: Each 350 mL of Dishwashing Liquid contains
Sodium Lauryl Ether Sulfate 1.083% 1.082%
3.2 Degradation product
3.3 Homogeneity nmt 6% 5%
4. Microbiological Testing
4.1 Standard Plate Count nmt 100 cfu 0 cfu
4.2 Salmonella Count 0 cfu 0 cfu
4.3 Coliform Count 0 cfu 0 cfu
4.4 Molds and Yeast Count nmt 10 cfu 0 cfu
dishwashing liquid also has various informal applications, such as for creating bubbles, clothes
washing and cleaning oil-affected birds.
The blending procedure or method was used during the process. The ingredients were
added in the order listed with continuous mixing until a clear, smooth and homogenous batch is
obtained that is free of lumps and particles. Laboratory equipments are essential in the
manufacture of various products. One of the materials used in product manufacture is the
analytical balance. An analytical balance (often called a "lab balance") is a class of balance
designed to measure small mass in the sub-milligram range. Beaker is a common container in
most laboratory. It is used for mixing, stirring, and heating chemicals. Hot plates for laboratory
use provide a good source of heating for reactions and other testing procedures. A glass rod,
stirring rod or stir rod is a piece of laboratory equipment used to mix chemicals and liquids for
laboratory purposes. They are usually made of solid glass, about the thickness and slightly longer
than a drinking straw, with rounded ends. A graduated cylinder, measuring cylinder or mixing
cylinder is a common piece of laboratory equipment used to measure the volume of a liquid. It
has a narrow cylindrical shape. Each marked line on the graduated cylinder represents the
amount of liquid that has been measured.
STABILITY STUDY
Packaging
1. Immediate: Amber Bottle with PP cap Temperature: 40° C
2. Secondary: Box Relative Humidity: 75%
pH 7-8 8 8 8 8 8
Viscosity 200-500 cps 300 cps 300 cps 300 cps 300 cps 300 cps
Homogeneity Nmt 6% 5% 5% 5% 5% 5%
STABILITY STUDY
Packaging
1. Immediate: Amber Bottle with PP cap Temperature: 30° C
2. Secondary: Box Relative Humidity: 75%
pH 7-8 8 8 8 8 8
Viscosity 200-500 cps 300 cps 300 cps 300 cps 300 cps 300 cps
Homogeneity Nmt 6% 5% 5% 5% 5% 5%
PACKAGING
Label