5/13/2021 Profiling some plant-based immunomodulatory bioactive compounds for COVID-19 prophylaxis and treatment based on Indian traditi…

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Profiling some plant-based immunomodulatory bioactive

compounds for COVID-19 prophylaxis and treatment
based on Indian traditional medicine
B Y P R A K R I TY S I N G H , S H R A D D H A PA N D I T A N D R A M A K R I S H N A N PA RT H A S A R AT H I | 1 9
F E B R UA RY 2 0 2 1

Traditional medicines, alongside the ongoing therapeutic system, have

the potential to provide effective treatments, improving the synergistic
effects and prioritization of plant-based bioactive compounds in
combating SARS-CoV-2

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The pandemic caused by SARS-CoV-2 or COVID-19 has imposed several challenges on the
current healthcare system around the world. Despite the significant effort to contain the COVID-19
epidemic, the situation has entered a vicious stage without any proven prophylaxis strategy for the
treatment of mild, moderate, and severe conditions. Though there are diverse therapeutics at
various stages of development, the utilization of traditional medicine offers a requisite immune
response to different phases of COVID-19 infection. As herbal-based drugs present a conventional
knowledge, in this review we have provided a pragmatic classification of medicinal plants based
upon suitable immunomodulation properties at multiple stages starting from prevention to
contagion, such as infection, immunosuppression, and stages involving multi-organ failure as well
as recovery management. Systematic compilation and classification of plant-based bioactive
chemicals was carried out for mild, moderate, and severe conditions COVID-19 and relevant
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5/13/2021 Profiling some plant-based immunomodulatory bioactive compounds for COVID-19 prophylaxis and treatment based on Indian traditi…

clinical trials. The traditional medicinal approaches with the ongoing therapeutic system have the
potential to provide effective treatments, improving the synergistic effects and prioritization of
plant-based bioactive compounds in combating SARS-CoV-2.

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