Drug Mechanism of action/ Side effects
Brand name: Mechanism of Action
 Ascriptin. The acetyl group of acetylsalicylic
Generic name: acid binds with a serine residue of
 Aspirin the cyclooxygenase-1 (COX-1)
Classification: enzyme, leading to irreversible
 non-steroidal inhibition. This prevents the
anti-inflammatory production of pain-causing
drug (NSAID). prostaglandins. These agents reduce
Route: the signs and symptoms of
 PO inflammation and exhibit a broad
Dosage: range of pharmacologic activities,
 80mg including analgesic, antipyretic, and
antiplatelet properties.
Frequency:
 OD
Side effects:
Conditions of excess stomach acid
secretion, irritation of the stomach or
intestines, nausea, vomiting,
heartburn, stomach cramps
Indication/ Contraindication
Indication:
Aspirin is used to reduce fever and relieve
mild to moderate pain from conditions such
as muscle aches, toothaches, common cold,
and headaches. It may also be used to
reduce pain and swelling in conditions such
as arthritis.
Contraindication:
Contraindicated to patients with uncontrolled
high blood pressure, bleeding disorders,
asthma, peptic (stomach) ulcers, liver and
kidney disease and lactation/ pregnant.
Nursing responsibilities
1. Check and verify with doctor’s order
and Kardex. Observe rights in
medication administration such as
giving the right drug to the right
patient using the right route and at
the right time.
2. Administer drug with food or after
meals if GI upset occurs. And give
drug with full glass of water to
reduce risk of tablet or capsule
lodging in the esophagus.
3. Ensure that patient does not crush
and chew tablets as well as
sustained release preparations to
prevent losing drug’s effectivity.
4. Educate patient that he/she may
experience these side effects:
Nausea, GI upset, heartburn (take
drug with food); easy bruising, gum
bleeding (related to aspirin’s effects
on blood clotting). Also instruct
 client to use soft-bristled toothbrush
and electric razor to prevent
bleeding.
5. Report ringing in the ears;
dizziness, confusion; abdominal
pain; rapid or difficult breathing;
nausea, vomiting, bloody stools