Scribd Logo
Upload

Welcome to Scribd!

  • Anatomy 1

    Uploaded by

    Jenna Lynn
    8 views1 page
    1) The neural regulation of GFR involves vasoconstriction and vasodilation of the afferent and efferent arterioles in response to sympathetic stimulation levels. During rest, vasodilation occurs, while moderate stimulation causes constriction restricting blood flow in and out to the same degree, slightly decreasing GFR. Large stimulation causes dominant afferent vasoconstriction, dropping glomerular blood flow and GFR. 2) Hormonal regulation of GFR involves angiotensin II which narrows the arterioles, reducing blood flow and GFR, while ANF increases blood volume and stretches the atria, releasing ANF which increases glomerular surface area and

    Original Description:

    Original Title

    Anatomy.1

    Copyright

    © © All Rights Reserved

    Available Formats

    PDF, TXT or read online from Scribd

    Did you find this document useful?

    Is this content inappropriate?

    Report this Document
    1) The neural regulation of GFR involves vasoconstriction and vasodilation of the afferent and efferent arterioles in response to sympathetic stimulation levels. During rest, vasodilation occurs, while moderate stimulation causes constriction restricting blood flow in and out to the same degree, slightly decreasing GFR. Large stimulation causes dominant afferent vasoconstriction, dropping glomerular blood flow and GFR. 2) Hormonal regulation of GFR involves angiotensin II which narrows the arterioles, reducing blood flow and GFR, while ANF increases blood volume and stretches the atria, releasing ANF which increases glomerular surface area and

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    8 views1 page

    Anatomy 1

    Uploaded by

    Jenna Lynn
    1) The neural regulation of GFR involves vasoconstriction and vasodilation of the afferent and efferent arterioles in response to sympathetic stimulation levels. During rest, vasodilation occurs, while moderate stimulation causes constriction restricting blood flow in and out to the same degree, slightly decreasing GFR. Large stimulation causes dominant afferent vasoconstriction, dropping glomerular blood flow and GFR. 2) Hormonal regulation of GFR involves angiotensin II which narrows the arterioles, reducing blood flow and GFR, while ANF increases blood volume and stretches the atria, releasing ANF which increases glomerular surface area and

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 1

    •

    Neural Regulation Of GFR at Diff Stimulation s I 2


    what
    .

    During rest
    -
    .

    sympathetic stimulation
    •
    IS low

    •
    Afferent ! Efferent arterioles are dilated
    thymolorgy
    Renal auto regulation of GFR dominates
    •

    During moderate stimulation


    -

    •
    Afferent } efferent arterioles constrict
    •
    blood flow in & out is restricted to same degree
    •
    GFR decreases slightly

    During large stimulation


    -

    •
    vasoconstriction of afferent arteriole dominates
    •
    flow to Glomerulus drops → GFR drops
    ↳
    Reduced urine output & greater flow to other tissues
    -0 Hormonal Regulation of GFR

    Angiotensin 11 : vasoconstrictor Narrows afferent ÷ efferent arterioles reduces flow


    -

    , ,
    →
    reduces GFR
    Atrial Natur Hic factor increases blood volume stretches atria → release ANF
    -

    : ,

    ANF → releases me sandlot cells → 9 surface area → TGFR


    0
    Outcomes of tubular Reabsorption & secretion
    -

    Reabsorption : return of most filtered water ÷ solutes to the bloodstream


    ↳ 99% water is reabsorbed
    ↳ solutes are reabsorbed ( Na ,
    K, Ca , Hcoz ,
    HPO 4)
    ↳ small proteins } peptides are absorbed via phagocytosis
    -

    secretion : transfer of materials from blood } tubule cells into the tubular (luminal
    fluid )
    ↳ secretion of Ht
    helps regulate blood pH
    ↳ secretion of the rest is waste / detoxification
    0
    Tubular Reabsorption ! secretion routes
    -

    Reabsorption : More from lumen back to blood


    •
    para cellular reabsorption : brethren adjacent tubule cells ( be tight junctions are not
    ↳ DIFFUSION
    perfect )

    •
    Tran cellular reabsorption : through adjacent tubule cells
    →
    0
    Tubular Reabsorption & secretion transport mechanisms
    Primary Active Transport :
    hydrolysis of STP used to pump
    -

    Seco nary Active Transport :


    Energy in maintaining graint / gradient used to transport

    You might also like