1.

Viruses
Contain both DNA and RNA
May have an envelope
Have their own metabolism
May contain enzymes for replication
Cell
6. wall Simplex Encephalitis
Herpes
2. The following
Commonly affect are
the DNA viruses
temporal lobe
Herpesviruses
Is usually diagnosed by culture of the CSF
Orthomyxoviruses
May be diagnosed by PCR of the CSF
Enteroviruses
Should be treated with IV ganciclovir
Hepadnaviruses
May be diagnosed by the finding of specific antibody in the CSF
 Parvoviruses
3.7.The
Thefollowing
followingare RNA viruses
statements are true of Varicella-Zoster Virus
 Picornaviruses
Adenoviruses
Causes a maculopapular rash
Papillomaviruses
Respond to AZT therapy
Rhabdoviruses
Remains latent in sensory ganglia following primary infection
Rotaviruses
Recurrent episodes of Shingles usually occur
 
Patients with shingles are not infectious
 4. Live attenuated vaccines are available against the following
viruses
8. Cytomegalovirus (CMV)
Influenza A Virus
Primary infection is usually symptomatic
Hepatitis B Virus
An infectious mononucleosis-like syndrome may occur during primary
Rubella Virus
infection.
Yellow
May Fever
cause Virus 
severe infection in immunocompromised individuals
Varicella-Zoster
Is teratogenic Virus
 
Causes Kawasaki's Disease
 5. The following antiviral agents is active against the following virus
Lamivudine
9. and HIV
Epstein-Barr Virus (EBV) is associated with
Lamivudine
Infectious and HBV
Mononucleosis
Amantidine and Influenza B virus
Hepatitis
Ribavirinlymphoma
Burkitt's and RSV
Acyclovir and HSV
Nasopharyngeal carcinoma
 
Oral leukoplakia 
 
10. HHV-6 is associated with
Fifth disease  
Roseala Infantum  
Kaposi's Sarcoma
Infectious Mononucleosis-like illness
Oral leukoplakia
 
 

 
 

11. Adenoviruses
Are associated with genital cancers
May cause gastroenteritis
May cause conjunctivitis
May cause pneumonia
May cause warts
 
12. Papillomaviruses
HPV-6 and HPV-11 are associated with genital cancers
HPV-16 and HPV-18 are associated with genital cancers
Warts caused by papillomaviruses may respond to interferon therapy
Papillomavirus infection is commonly diagnosed by viral culture
Are associated with progressive multifocal leucoencephalopathy (PML)
 
13. Coxsackie B Virus is associated with the following
 
Paralytic illness
Myocarditis
Bornholm's disease
Severe congenital infection
Meningitis
 
14. Influenza A Virus
May undergo antigenic shift and antigenic drift
May cause pandemics
Respond to rimantidine
Respond to neuraminidase inhibitors
Vaccination confers lifelong protection
 
15. Paramyxoviruses may cause
Croup
Maculopapular rash
Pneumonia
Bronchiolitis
Diarrhoea
16. Respiratory Syncytial Virus (RSV)
 
Respond to Amantidine
May cause bronchiolitis 
May cause croup
 
May cause pneumonia
 
May be prevented by vaccination
 
17. Parvoviruses
 
Causes Roseola Infantum  
Causes Erythema Infectiousum
Is teratogenic
21. HIV Infection may lead to
May cause abortion
Dementia
May cause aplastic crisis in persons with haemolytic anaemias
Chronic Diarrhoea
 
CMV retinitis
18. Measles Virus Infection
Oesophageal candidiasis
Causes a vesicular rash
Non-Hodgkin's lymphoma
May cause encephalitis
 
May respond to acyclovir
22. The following may be useful for prognostic purposes in HIV-
May be prevented
infected by HNIG
individuals 
May be prevented
HIV envelope by vaccination
antibody
 HIV-p24 antigen
19.
CD4Rubella
count Virus
The
HIVrash of rubella
pro-viral DNAisinsimilar to that caused by parvo and enteroviruses
leucocytes
Is
HIVteratogenic
plasma RNA
Congenital
  rubella is charaterised by eye, ear and heart defects
Congenital
23. A chronicrubella is diagnosed
carrier state maybyoccur
the finding
in the of rubella-specific
following:
antibody in the cord blood of infants
Hantavirus Infection
Infants with congenital rubella poses a great infectious risk.
Hepatitis A
 
Hepatitis B
20. Human T-lymphotropic virus 1 (HTLV-1) is associated with
Hepatitis C
Burkitt's lymphoma
Smallpox Infection
Adult T-cell lymphoma
 
Tropical Spastic Paraparesis
24. The following markers are usually present in a hepatitis B
Multiple Sclerosis
carrier with chronic active hepatitis
Hodgkin's
HbeAg lymphoma
 Anti-HBc IgG
Anti-HBc IgM
HBV-DNA
HbsAg
 
25. The following statements are true
Chronic HBV infection may respond to interferon therapy
Chronic HCV infection may respond to interferon therapy
Chronic
26. HCV infection
The following maycan
viruses respond to ribavirinbytherapy
be transmitted blood
Delta infection may be prevented by vaccination against HBV
Hepatitis A
Hepatitis E Infection may be prevented by vaccination
HIV
HTLV-1
HBV
HCV  
   
27. Regarding viral infection of the central nervous system (CNS)
Meningitis may occur together with encephalitis
Enteroviruses are one of the commonest causes of CNS infections in
childhood
HSV encephalitis is a postinfectious encephalomyelitis
Measles encephalitis is a postinfectious encephalomyelitis
The detection of antibody in the CSF is a useful diagnostic marker
 
28. The following viruses are associated with gastroenteritis
Astroviruses
Norwalk-like viruses
Caliviruses
Adenoviruses
Rotaviruses
 
29. The following viruses are transmitted from animals to humans
Rabies Virus
Polioviruses
CMV
Hantaviruses
Lassa Fever Virus
 
30. The following is true of rabies virus
The majority of cases worldwide result from bat bites
Infection may be prevented by active and passive immunisation
Rabies vaccine is a live attenuated vaccine
The animal reservoir differ from country to country
May be diagnosed by serology