силлабус англ.ОМ-1, 2021-2022

Кафедра фармакологии, фармакотерапии и клинической фармакологии 044-41/
Рабочая программа дисциплины (Силлабус) Образовательная программа «Общая медицина» 1стр. из 32
Department of "Pharmacology, Pharmacotherapy and Clinical Pharmacology"

Working program of the discipline (Syllabus)
Educational program 6B10101 " General Medicine»
1. General information about the discipline

1.1 Discipline code: Farm 3203-1 1.6 Academic year: 2021-2022
1.2 Name of the discipline: Pharmacology 1.7 Course:3
1.3 Prerequisites: molecular biology and 1.8 Semester:5
medical genetics, physiology 1-2,
anatomy 1-2, Latin.
1.4 Post-requirements: therapy, children's 1.9 Number of Credits (ECTS): 4
diseases
1.5 Cycle: DB 1.10 Component: KV
2. Description of the discipline (maximum 150 words)
Pharmacology in the system of higher medical education is one of the fundamental sciences and provides a theoretical basis for the rational use of medicines
in medical practice. Based on the courses of normal and pathological physiology, biochemistry, pharmacology is the link between the biomedical and clinical
disciplines.
Pharmacology has a great influence on the development of medical and biological disciplines. For experimenters, the main value of pharmacological agents
is that they represent a wide range of possibilities for controlling many biochemical and physiological processes.
The progress of pharmacology inevitably influences the development of clinical disciplines. Recent years have been marked by the rapid development of
pharmacology, the emergence of new groups of drugs, as a result of which pharmacotherapy has become a universal method of treating most diseases. Thus,
pharmacology occupies an important place in the system of medical education, so knowledge of pharmacology is necessary for a doctor of any profile.
3. Summative assessment form

3.1  Testing 3.5 Coursework
3.2 Written 3.6 Essay
3.3 Oral 3.7 Project
3.4  OSPE 3.8 Other (specify)
4. Objectives of the discipline
To form students ' skills of clinical thinking, choice of medicines in adults and children with major syndromes of internal diseases.
Department of Pharmacology, Pharmacotherapy and Clinical Pharmacology 044-41/
Working program of the discipline (Syllabus) Educational program " General Medicine» 2стр. из 32
5. Final learning outcomes (the result of learning the discipline)

RL Knowledge and understanding
1 Demonstrates knowledge of the pharmacokinetics and pharmacodynamics of drugs, their adverse reactions, indications and contraindications to use,
depending on the pathological condition, syndromes.Focuses on the classification and nomenclature of medicines.
RL2 Applying knowledge and understanding
Selects drugs for the treatment of pathological conditions in accordance with the mechanism of action and pharmacokinetic parameters
RL3 Applying knowledge and understanding
Prescribes prescriptions for medicines, determines the dosage regimen of the drug.
RL4 Forming judgments
It is able to compare drugs in pharmacological groups, generations (generations).
RL5 Forming judgments
Uses treatment protocols for drug selectio
RL6 Communication skills
Provides information about medicines to specialists and non-specialists
RL7 Academic ability
Searches for information on medicines in the evidence-based medicine database
5.1 RL of disciplines Learning outcomes of the educational program that are associated with the learning outcomes of the discipline
RL1 RL 1 Demonstrates knowledge and understanding of biomedical sciences for diagnosis, treatment, dynamic
RL2 observation of the most common diseases in adults and children.
RL3
RL4
RL5 RL 2 Capable to conduct outpatient appointments based on evidence-based medicine principles, diagnostics,
RL6 treatment, dynamic observation and rehabilitation of children and adults, including pregnant women, and determines
RL 7 the indications for hospitalization.
6. Detailed information about the discipline
6.1 Venue (building, auditorium): South Kazakhstan Medical Academy, main building, Department of Pharmacology, Pharmacotherapy and
Clinical Pharmacology. Al-Farabi Square-1, 4th floor, auditorium No. 419,421,425,429,431,434 , No. 4 lecture hall. Phone (PBX) 40-82-06. v \
n 227
6.2 Number of hours Lectures Practical Laboratory SR SROP
exercises classes O
10 30 56 24
7. Information about teachers
№ Full name Degrees and Email address Research interests, etc. Progress
position
1 Akhmadieva K. E. Candidate of akhmadievak@mail.ru Social and medical-organizational Author of about 50 scientific
Medical Sciences, bases of tuberculosis control in papers, textbooks, lectures, and
Acting Associate South Kazakhstan region guidelines
Professor Head of
the Department
2 Ormanov Doctor of ormanоv48n@mail.ru "Development and implementation Author of more than 190 scientific
Namazbay Medical of phytopreparations for the papers, textbooks, and guidelines.
Zhapparovich Sciences, prevention and treatment of socially Excellent Student of Healthcare of
Professor significant diseases» the Republic of Kazakhstan
3 Social and medical-organizational Author of 10 scientific papers,
Abdiganiev Akmal teacher Akmal-x@mail.ru bases of the fight against diseases methodological recommendations
Abdiganievich of the cardiovascular system in
Shymkent
4 Nematullaev Teacher Babur1010@gmail.com Modern methods of treatment of Author of 8 scientific papers,
Baburzhan Neurosurgeon adhesive diseases methodological recommendations
Maribkhanovich Doctor
5 Tursunov Teacher Davlat_077@list.ru Social and medical-organizational Author of 7 scientific papers,
Davlatbek Family-doctor bases of the fight against diseases methodological recommendations
Ulukbekovich of the urinary system.
6 Ablaikhan Teacher Abl7@bk.ru Use of 3D membrane mesh for the Author of 9 scientific papers,
Baimakhanov Doctor-Surgeon treatment of parenchymal organs methodological recommendations
7 Dembayev Teacher trzdes@gmail.com Social and medical-organizational Author of 8 scientific papers,
Yerkebulan Family-doctor bases of the fight against diseases methodological recommendations
Sovetovich of the urinary system.
8. Thematic plan
Wee Topic name Synopsis The result of Number Forms/methods/

k/ learning the of hours technologies of Assessment forms/
Day discipline training methods
1 Lecture. Definition of pharmacology, content RL 1 1 Overview Feedback
Introduction. Pharmacology as a and main tasks of pharmacology.
scientific discipline. History of The relationship of pharmacology
development. Pharmacokinetics, with biomedical and clinical
pharmacodynamics of drugs.Interaction disciplines.
of drugs. The main regulatory documents
regulating the rules for prescribing
medicines. General rules for drawing
up, writing out prescriptions and
issuing them from the pharmacy of
medicines. Forms of prescription
forms. Rules for prescribing dosage
forms in prescriptions.
Pharmacokinetics of drugs,
definition and content. Ways of
introducing drugs into the body. The
main parameters of
pharmacokinetics.
Pharmacodynamics of medicinal
products, definition and content.
Primary pharmacological
reaction( effect), localization and
mechanism of action of drugs. Types
of action of medicinal substances.
Factors affecting the
pharmacokinetics and
pharmacodynamics of drugs.
Features of pharmacokinetics of
drugs in pregnant women.

Features of pharmacokinetics and
pharmacodynamics of drugs in the
fetus.
Features of pharmacotherapy in
newborns and children.
Features of pharmacotherapy for the
elderly
Changes in the effects caused by
drugs when two or more drugs are
used simultaneously or sequentially.
Types of drug interactions.
Combination of medicines.
Mechanisms for controlling adverse
drug reactions.
Practical lesson Definition of pharmacology, content RL 1,2 2 Working in small Oral discussion, dose
Introduction. Pharmacology as a and main tasks of pharmacology. groups calculation,
scientific discipline. History of The relationship of pharmacology prescribing
development. Pharmacokinetics with biomedical and clinical
pharmacodynamics of drugs.Interaction disciplines.
of medicines. The principle of finding new
medicines. Synthesis of new drugs
based on the study of the relationship
between the chemical structure and
the action of substances.
The main regulatory documents
regulating the rules for prescribing
medicines. Rules for the release of
medicines from pharmacies.
General rules for drawing up, writing
out prescriptions and issuing them
from the pharmacy of medicines.

Forms of prescription forms. Rules
for prescribing dosage forms in
prescriptions. Solid, soft and liquid
dosage forms.
Dosage forms for injection. Other
dosage forms. Features of
prescribing toxic, potent, narcotic
drugs and drugs with an intoxicating
effect.
Pharmacokinetics of drugs,
definition and content. Ways of
introducing drugs into the body.
Advantages and disadvantages of the
main routes of administration.
Absorption of drugs in various routes
of administration. The main
mechanisms of absorption and the
factors affecting them. Distribution
of medicinal substances in the body,
factors affecting it. Biological
barriers. Transport of medicinal
substances. Escrow. The
transformation of medicinal
substances in the body. Ways to
remove drugs from the body.
Presystemic elimination of medicinal
substances. The main parameters of
pharmacokinetics. The concept of
bioavailability and bioequivalence.
Mathematical modeling of
pharmacokinetic processes.
Pharmacodynamics of medicinal
products, definition and content.
Primary pharmacological
reaction( effect), localization and
mechanism of action of drugs. Basic
principles of the action of medicinal
substances. The concept of specific
receptors, agonists and antagonists.
Types of connection of medicinal
substances with biomolecules of the
body. Types of action of medicinal
substances. Factors affecting the
pharmacokinetics and
pharmacodynamics of drugs.
Features of pharmacokinetics of
drugs in pregnant women.
Features of pharmacokinetics and
pharmacodynamics of drugs in the
fetus.
Features of pharmacotherapy in
newborns and children.
Features of pharmacotherapy for the
elderly
Independent work of students with a 1. The main regulatory documents RL 1,5,6,7 4 Protection of Checklist
teacher regulating the rules for prescribing presentations, (presentation,
1. The task of the Independent work of medicines. Forms of prescription abstracts. abstract).
students . The main regulatory forms. Rules for prescribing dosage
documents regulating the rules for forms in prescriptions.
prescribing medicines
2 Lecture. Means of an oppressive type of RL 1 1 Overview Feedback

Means that affect afferent innervation action. Drugs that depress sensitive
nerve endings
and / or conduct arousal along the
afferent nerves. Local anesthetics.
Definition.
Classification. Requirements for
local anesthetics. Localization and
mechanism of action. Astringents,
enveloping and irritating agents.
Means of an oppressive type of
action. Drugs that depress sensitive
nerve endings and / or conduct
arousal along the afferent nerves.
Local anesthetics. Definition.
enveloping and irritating agents.
Practical lesson Means of an oppressive type of RL 1,2,3,4,5 2 Working in small Oral discussion, dose
Means that affect afferent innervation action. Drugs that depress sensitive groups, calculation,
nerve endings and / or conduct prescribing
arousal along the afferent nerves.
Local anesthetics. Definition.

enveloping and irritating agents
Independent work of students with a 1. Basic parameters of RL 6,7 4 Protection of Checklist
teacher pharmacokinetics and presentations, (presentation,
1. The task is Independent work of pharmacodynamics. abstracts. abstract).
students.
Basic parameters of pharmacokinetics
and pharmacodynamics.
3 Practical lesson General characteristics of the RL 2,3,4,5 2 Working in small Oral discussion, dose
Means that affect the efferent autonomic nervous system. Structure groups calculation,
innervation. and function of the cholinergic prescribing
Cholinergic agents synapse.
Localization of M - and N-
cholinergic receptors. Characteristics
of muscarinoand
nicotinocholinoreceptors, their
subtypes. Classification of agents
that affect the transmission of
excitation in cholinergic synapses.
Anticholinesterase agents (M - and N
- cholinomimetic agents of indirect
type of action).
Main effects. Comparative
characteristics of drugs and their use.
Features of the action of
organophosphorus compounds.
Side and toxic effects of
anticholinesterase agents. Treatment
of poisoning. The use of

cholinesterase reactivators
(dipyroxime, alloxime, isonitrosine)
in poisoning with organophosphorus
compounds.
M-and N-holinoblokiruyushchy
means.
Drugs that affect M-cholinergic
receptors
Effect on the eye (pupil size,
intraocular pressure,
accommodation), smooth muscles of
internal organs, gland secretion.
Comparative characteristics of drugs.
Application. Toxic effect of
muscarine. Treatment of poisoning.
M-holinoblokiruyushchy means
The main pharmacological effects.
The effect of atropine on the eye,
cardiovascular system, smooth
muscles, and glands. Features of the
action... Preparations of belladonna.
Application. Atropine poisoning and
help with it. Features of the action
and application of platyphylline,
ipratropium bromide. Selectively
acting M-cholinoblockers
(pirenzepine, tiotropium bromide).
Independent work of students with a 1. Age-related aspects of the use of RL 6,7 8 Protection of Checklist
teacher drugs. Principles of pharmacotherapy presentations, (presentation,
1. Task independent work of students in gerontology. abstracts. abstract).
Age-related aspects of the use of drugs. 2. Interaction of drugs. Prevention of

2. Task independent work of students undesirable side effects.
Interaction of drugs. Prevention of
undesirable side effects
4 Lecture. Drugs that affect efferent General characteristics of the RL 1 1 Overview Feedback
innervation autonomic nervous system. Structure
Cholinergic drugs . and function of the cholinergic
Adrenergic drugs. synapse.
Localization of M - and N-
cholinergic receptors. Characteristics
of muscarinoand
nicotinoholinoreceptors, their
subtypes. Classification of agents
that affect the transmission of
excitation in cholinergic synapses
General characteristics of the
sympathetic nervous system.
Structure and function of the
adrenergic synapse.
Localization of alpha - and beta-
adrenergic receptors. Characteristics
of adrenoreceptors, their subtypes.
Classification of agents that affect
the transmission of arousal in
adrenergic synapses.
Practical lesson General characteristics of the RL 2,3,4,5 2 Working in small Oral discussion, dose
Means that affect the efferent sympathetic nervous system. groups calculation,
innervation. Structure and function of the prescribing
Adrenergic agents adrenergic synapse.
Localization of alpha - and betta-
adrenoreceptors. Characteristics of
adrenoreceptors, their subtypes.

Classification of agents that affect
the transmission of arousal in
adrenergic synapses. Drugs with
their own sympathomimetic activity.
Influence on the functions of organs.
Adrenoblocking agents.
Sympatholytic agents.
Adrenoblocking agents.
Pharmacodynamics of alpha-
blockers. Selective and non-selective
alpha-blockers. Application. Possible
complications.
The main properties and application
of beta-blockers. Beta-blockers with
selective action (metoprolol,
atenolol) and internal
sympathomimetic activity
(oxprenolol). Beta-blockers used to
treat glaucoma. Side effects of beta-
blockers. Alpha-and beta-blockers
( carvedilol).
Sympatholytic agents:
Localization, mechanisms of action
and main effects of octadine and
reserpine, their comparative
characteristics. Application. Side
effect.
Independent work of students with a 1. Irritating agents. Expectorants of RL 6,7 8 Protection of Checklist
teacher reflex action. Bitterness, laxatives presentations, (presentation,
1. Task independent work of students and choleretics of reflex action. Side abstracts. abstract).
Irritating agents. Expectorants of reflex effects.

action. 2. Poisoning of the FOS. Atropine
2. Task independent work of students poisoning. Symptoms, measures of
Poisoning of the FOS. Atropine help. Medications used
poisoning.
5 Lecture The concept of antibiotic therapy. RL 1 1 Overview Feedback
General principles of chemotherapy. Requirements for it. The main
Antibiotic resistance. Antiseptic and mechanisms of action of antibiotics.
disinfectant products The concept of basic and reserve
antibiotics. Antiseptic and
disinfectant products. Classification.
The mechanism of action.
Application. Biological significance
of antibiotics. The history of
obtaining and using antibiotics.
Classification principles. Principles
of combining antibiotics.
Practical lesson The concept of antibiotic therapy. RL 2,3,4,5 2 Case study. Oral interview.
General principles of chemotherapy. Requirements for it. The main Clinical case Solving test tasks
Antibiotic resistance. Antiseptic and mechanisms of action of antibiotics. discussion (CbD- and situational tasks.
disinfectant products The concept of basic and reserve Case based Writing prescriptions
antibiotics. Antiseptic and Discussion).
disinfectant products. Classification.
The mechanism of action. Working in small
Application. Biological significance groups
of antibiotics. The history of
obtaining and using antibiotics.
Classification principles. Principles
of combining antibiotics. Features of
use in children
Independent work of students with a 1. beta-blockers. Classification. RL 6,7 8 Journal Club (JC- Journal Club (JC-
teacher Indications for use. Side effects. Journalclub) Journalclub)

1. Task independent work of students 2. Antibiotic resistance. Causes of Checklist
beta-blockers. Classification. antibiotic resistance.
2. Task independent work of students
Antibiotic resistance.
6 Practical lesson Classification.Mechanism and RL 2,3,4,5 2 Working in small Oral discussion, dose
Chemotherapeutic agents. spectrum of antimicrobial action. groups calculation,
Antibacterial agents (antibiotics)– 1 part Beta-lactam antibiotics. Antibiotics prescribing
of the penicillin group: classification,
mechanism and spectrum of action
and pharmacokinetics of drugs.
Features of the action and application
of semi-synthetic penicillins.
Ureidopenicillins. Combined drugs
with beta-lactamase inhibitors.
Features of use in children
Independent work of students with a 1. Drugs that affect the immune RL 6,7 4 Protection of Checklist
teacher system presentations, (presentation,
1. Independent work of students abstracts. abstract).
Drugs that affect the immune system
7 Lecture Classification. Mechanism and RL 1 1 Overview
Chemotherapeutic agents. spectrum of antimicrobial action. (Feedback)
Antibacterial agents (antibiotics) Beta-lactam antibiotics. Antibiotics
of the penicillin group: classification,
Features of the action and application
of semi-synthetic penicillins.
Combined drugs with beta-lactamase
inhibitors. Antibiotics of the group of
aminoglycosides, tetracyclines,
lincosamines, macrolides,
glycopeptides, chloramphenicol and
other groups. Features of use in
children
Practical lesson Antibiotics of the group of RL 2,3,4,5 2 Working in small Oral discussion, dose
Chemotherapeutic agents. aminoglycosides, tetracyclines, groups calculation,
Antibacterial agents– antibiotics) - Part lincosamines, macrolides, prescribing
2 glycopeptides, chloramphenicol and
other groups. Classification,
Features of the action and use of
drugs. Features of use in children
Independent work of students with a Test tasks for all passed topics/ RL 2 Tickets Prescribing, oral
teacher Answer questions about programmed 1,2,3,4,5,6,7 interviewing
Midterm on the topic "General ticket control
pharmacology, general formulation and
drugs that affect the peripheral nervous
system. Drugs that affect the central
nervous system. Antimicrobial agents".
8 Lecture The relationship between the RL 1 1 Overview
Synthetic antimicrobial agents. structure of sulfonamides and their (Feedback)
antimicrobial activity. Mechanism
and spectrum of antimicrobial action.
Classification. Comparative
characteristics of drugs. Application.
Possible complications, their
prevention. Combined drugs with
trimethoprim. Features of the action
and application.
Synthetic antimicrobial agents of
different chemical structures.

Classification. Fluoroquinolones.
Nitrofuran derivatives. Mechanism
and spectrum of antimicrobial action.
Side effects. Features of use in
children
Practical lesson The history of the discovery. The RL 2,3,4,5 2 Working in small Oral discussion, dose
Synthetic antimicrobial agents relationship between the structure of groups calculation,
sulfonamides and their antimicrobial prescribing
activity. Mechanism and spectrum of
antimicrobial action. Classification.
Comparative characteristics of drugs.
Application. Possible complications
and their prevention. Combined
drugs with trimethoprim. Features of
the action and application. Sled
connections, their action and
application. Side effects.
Synthetic antimicrobial agents of
different chemical structures.
Fluoroquinolones. Nitrofuran
derivatives. General characteristics.
Mechanism and spectrum of
antimicrobial action. Side effects.
Independent work of students with a 1. Combination of antibacterial RL 6,7 8 Protection of Checklist
teacher agents. presentations, (presentation,
1. Combination of antibacterial agents. 2. Application of bacteriophages in abstracts. abstract).
2. Task independent work of students clinical practice
Application of bacteriophages in
clinical practice
9 Practical lesson The mechanism of action of RL 2,3,4,5 2 Working in small Oral discussion, dose
Drugs that affect immune processes. nonsteroidal anti-inflammatory groups calculation,
Anti-inflammatory drugs. Anti-allergic drugs. NSAIDs of different chemical prescribing
agents. groups.Indications and
contraindications for use.
Mechanism of action and use of anti-
allergic agents (diphenhydramine,
suprastin, clemastine,
chloropyramine, fexofenadine)
Immunostimulants. Classification.
Mechanism of action and
comparative characteristics of drugs.
Drugs from different
pharmacological groups that increase
the nonspecific resistance of the
body.
Immunosuppressants. Classification.
Independent work of students with a 1. Classification and mechanism of RL 6,7 4 Protection of Checklist
teacher action of antiviral agents. presentations, (presentation,
1. Classification and mechanism of Application. Biological significance. abstracts. abstract).
action of antiviral agents. Drugs for the treatment of AIDS
(azidothymidine). Possible side
effects.
10 Lecture The mechanism of action of RL 1 1 Overview
Drugs that affect the immune processes. nonsteroidal anti-inflammatory (Feedback)
Anti-inflammatory drugs. Anti-allergic drugs. NSAIDs of different chemical
agents. groups.Indications and

contraindications for use.
Mechanism of action and use of anti-
allergic agents (diphenhydramine,
suprastin, clemastine,
chloropyramine, fexofenadine)
Immunostimulants. Drugs from
different pharmacological groups
that increase the nonspecific
resistance of the body.
Immunosuppressants. Classification.
Practical lesson Classification and mechanism of RL 2,3,4,5 2 Working in small Oral discussion, dose
Antiviral agents. Antiprotozoal drugs. action of antiviral agents. groups calculation,
Antifungal agents. Application. Biological significance, prescribing
Anthelmintic agents. pharmacological effects, and use of
interferons. Interferonogens of AIDS
treatment agents. Possible side
effects.
Antiprotozoal drugs. Classification,
mechanism of action of drugs used to
treat malaria, amoebiasis,
trichomoniasis, leishmaniasis, etc.
Possible complications and their
prevention.
General characteristics. The
mechanism of antifungal action of
drugs of different groups.

Classification of anthelmintic agents.
Mechanism of action, Indications for
use.Contraindications. Features of
use in children
Independent work of students with a 1. Antiblastoma agents. RL 6,7 4 Protection of Checklist
teacher Classification, mechanism of action. presentations, (presentation,
1. Task independent work of students Features of the spectrum of abstracts. abstract).
Antiblastoma agents. Classification, antitumor action of alkylating agents,
mechanism of action. Features of the antimetabolites, antibiotics, herbal
spectrum of antitumor action of preparations, hormonal and
alkylating agents, antimetabolites, antihormonal preparations
antibiotics, herbal preparations, (tamoxifen, flutamide), various
hormonal and antihormonal drugs synthetic agents (prospidin),
enzymes (aspiraginase), platinum
preparations (cisplastin).
11 Lecture Classification and mechanism of RL 1 1 Overview/
Antiviral agents. Antiprotozoal drugs. action of antiviral agents. Problematic (Feedback)
Antifungal agents. Application. Funds for the treatment
Anthelmintic agents. of AIDS. Possible side effects.
Classification, mechanism of action
of drugs used to treat malaria,
amoebiasis, trichomoniasis,
leishmaniasis, etc.
The mechanism of antifungal action
of drugs of different groups.
Classification of anthelmintic agents.
Indications for
use.Contraindications. Features of
use in children
Practical lesson General characteristics. The RL 2,3,4,5 2 Working in small Oral discussion, dose
Anti-tuberculosis drugs. Anti-spirochete mechanism of antitubercular action groups calculation,

agents of drugs of different groups. prescribing
Classification. The mechanism and
spectrum of antibacterial action of
the main and reserve drugs, their
pharmacokinetics. Basic principles
of antitubercular therapy (duration
and number of floors of treatment,
combination therapy). Comparative
characteristics of individual drugs.
Side effect.
Principles of prescribing anti-
spirochete agents. Anti-spirochete
properties of benzylpenicillin
preparations. The mechanism of
action of bismuth preparations, their
use in the treatment of syphilis. Side
effect. Reserve anti-spirochete
antibiotics: tetracycline,
erythromycin, etc. Features of use in
children
Independent work of students with a 1. Antiblastoma agents. Monoclonal RL 6,7 4 Protection of Checklist
teacher antibodies-trastuzumab, rituximab, presentations, (presentation,
1. Antiblastoma agents. Monoclonal bevacizumab, cetuximab abstracts. abstract).
antibodies-trastuzumab, rituximab, Protein kinase inhibitors-imatinib,
bevacizumab, cetuximab gefitinib, erlotinib, temsirolimus and
other antitumor drugs: asparaginase,
hydroxycarbamide. Application in
medicine.
12 Practical lesson Classification. Comparative RL 2,3,4,5 2 Working in small Oral discussion, dose
Antiblastoma agents characteristics of drugs. Application. groups calculation,
Possible complications and their prescribing

prevention.
General characteristics. The
mechanism of antiblastoma action of
drugs of different groups. Features of
use in children
Independent work of students with a 1. Glucocorticoids for systemic and RL 6,7 4 Protection of Checklist
teacher topical use. Drugs used for Itsenko- presentations, (presentation,
1. Task independent work of students Cushing's disease. abstracts. abstract).
Glucocorticoids for systemic and topical
use.
13 Lecture Classification of hormonal agents. RL 1 1 Overview
Hormonal drugs. Corticosteroids The mechanism of action. (Feedback)
Indications and contraindications.
The mechanism of action of steroid
anti-inflammatory drugs. Indications
for use. Contraindications. Features
of use in children
Practical lesson Classification of hormonal agents. RL 2,3,4,5 2 Case study. Oral interview.
Hormonal drugs.Corticosteroids. The mechanism of action. Clinical case Solving test tasks
Indications and contraindications. discussion (CbD- and situational tasks.
The mechanism of action of steroid Case based Writing prescriptions
anti-inflammatory drugs.Indications Discussion).
for use.Contraindications . Features Working in small
of use in children groups
Independent work of students with a 1. Pharmacotherapy of disorders RL 6,7 2 Journal Club (JC- Journal Club (JC-
teacher of cerebral circulation. Journalclub) Journalclub)
1. Task independent work of students General ionizing agents. Checklist
Pharmacotherapy of disorders of
cerebral circulation.
14 Lecture Classification of medicines. The RL 1 1 Overview/
Drugs that affect the central nervous mechanism of action. The main Problematic (Feedback)
system. Sleeping pills. Anticonvulsants, pharmacological effects.
antiepileptic drugs. Comparative characteristics of drugs
and their use. The choice of an
antiepileptic drug depends on the
type of seizure and the form of
epilepsy. Advantages of modern
antiepileptic drugs (lamotrigine,
tiagabine, etc.) features of use in
children. General principles of
pharmacotherapy of meningitis.
Classification, mechanism of action,
indications,
contraindications.Features of use in
children.
Drugs used in parkinsonism.
Practical lesson Classification of medicines. The RL 2,3,4,5 2 Working in small Oral discussion, dose
Drugs that affect the central nervous mechanism of action. The main groups calculation,
system. Sleeping pills. Anticonvulsants, pharmacological effects. prescribing
antiepileptic drugs. Comparative characteristics of drugs
and their use.
Conservative treatment of epilepsy.
The choice of an antiepileptic drug
depends on the type of seizure and
the form of epilepsy. Advantages of
modern antiepileptic drugs
(lamotrigine, tiagabine, etc.) features
of use in children. Meningitis
(meningitis) is a syndrome of
damage to the meninges. General
principles of pharmacotherapy of
meningitis. Classification,
mechanism of action, indications,
contraindications.Features of use in
children.
Drugs used in parkinsonism.
Levodopa + dopa-decarboxylase
inhibitors, dopamine receptor
agonists (adr), monoamine oxidase –
b (mao – b) inhibitors, n-methyl-d-
aspartate (glutamate) antagonists,
anticholinergic agents. Features of
use in children
Independent work of students with a 1. Neurological drugs. Drugs used in RL 6,7 2 Protection of Checklist
teacher Parkinson's disease presentations, (presentation,
1. Task independent work of students to abstracts. abstract).
receive drugs. Drugs used in
Parkinson's disease
15 Psychotropic drugs. Drugs that depress Classification of medicines. The RL 2,3,4,5 2 Working in small Oral discussion, dose
the central nervous system.Drugs that mechanism of action. The main groups calculation,
stimulate the central nervous system pharmacological effects. prescribing
Comparative characteristics of drugs
and their use.
Principles of drug therapy for
depressive syndrome.
Antidepressants (duloxetine,
sertraline, fluoxetine, fluvoxamine,
mirtazapine, agomelatin,
venlafaxine), sleeping pills
(zopiclone), tranquilizers (diazepam,
phenazepam, clonazepam).
Antipsychotic drugs. Antipsychotics

(olanzapine, quetiapine, risperidone,
paliperidone, amisulpride, sulpiride,
clozapine, haloperidol,
trifluoperazine,
levomepromazine, chlorpromazine).
Normotimic drugs (carbamazepine,
valproic acid, lamotrigine,
topiramate). Features of use in
children
Independent work of students with a Test tasks for all passed topics/ RL 1,2,3,4 2 Tickets Prescribing, oral
teacher Answer questions about programmed 6,7 interviewing
Midterm on the topic "Means that affect ticket control
the function of the executive organs and
the endocrine system, the blood system
and the central nervous system".
Number of hours 108
Preparation and conduct of interim 12
certification
22 Total number of hours of discipline 120
9. Teaching and learning methods
9.1 Lectures Review, problem review of lectures in the form of a lecture-presentation or text material, lecture materials included
in the module "Task", feedback questions; lectures-presentations on the ZOOM platform, WEBEX MEET, feedback
from the audience blitz survey of students on the topic of the lecture
9.2 Practical exercises Working in small groups; Case study. Clinical case discussion (CbD-Case based Discussion). individual work in the
op-line communication mode and/or in the off-line mode for completing tasks presented in the "Task" module;
discussion in the op-line mode or in the chat of the "Task" module or on other platforms (Zoom, Webex).
9.3 SRO/SROP Presentation, abstracts, Journal Club (JC – Journalclub) on the topic in accordance with the schedule of SRO
delivery;
In the conditions of distance learning, tasks are performed on the Platonus platform in the "Task" module; in
addition, the teacher conducts an on-line discussion of SRO using various information platforms and social networks
(group call Wathsapp, Zoom, Webex, Skype, etc.).

9.4 Midterm Tickets; in the conditions of distance learning, an oral survey of tickets, prescribing prescriptions using audio and
video surveillance, an oral survey in online mode in the video conference mode on the ZOOM and WEBEX
MEETINGS platforms.
9.5 Intermediate control OSP. Testing.
In the conditions of distance learning, an online exam/testing on the "Proctoring" platform, an on-line OSPE using
audio and video surveillance, and an online survey are used.
10. Evaluation criteria
Rating by letter Digital equivalent of Percentage content Assessment according to the traditional system
system points
А 4,0 95-100 Great
А- 3,67 90-94
В+ 3,33 85-89 Well
В 3,0 80-84
В- 2,67 75-79
С+ 2,33 70-74
С 2,0 65-69 Satisfactory
С- 1,67 60-64
D+ 1,33 55-59
D- 1,0 50-54
FX 0,5 25-49 Unsatisfactory
F 0 0-24
11. Learning resources
Electronic resources, including, 1."Consultant student " (GEOTAR), which represents full access to modern educational literature on all disciplines. A link
but not limited to: databases, to access: http://www.studmedlib.ru, login ibragim123, password Libukma123
animation simulators, 2. SKMA repository http://lib.ukma.kz/repository/
professional blogs, websites, 3. Republican Interuniversity Electronic Library http://rmebrk.kz/
other electronic reference 4. Digital Library" Akpigress " https://aknurpress.kz/login
materials (for example: video, 5. Database of normative legal acts" Law " https://zan.kz/ru
audio, digests) 6. Information System" paragraph Medicine " https://online.zakon.kz/Medicine/
7.Thomson Reuters (Web of science) www.webofknowledge.com

8.ScienceDirect http://www.sciencedirect.com/
9.Scopushttps://www.scopus.com/
Electronic textbooks 1. Kharkevitch, D. A. Pharmacology [Electronic resource] :textbookformedicalstudents / D. A. Kharkevitch. -
Electron.text data. ( 83.9 Mb). - Moscow: GEOTAR-Media, 2017. - e.opt. Disk
2. Pharmacology [Electronic resource]: okukuraly / ed. bas. G. M. Pichkhadze = Pharmacology: textbook / ed. G. M.
Pichkhadze. - Electron.text data (43.0 Mb). - M.: "Litterra", 2016. - 504 bet p.
3. Maisky, V. V. Pharmacology with a general recipe [Electronic resource]: textbook for medical schools and colleges / V.
V. Maisky, R. N. Alyautdin. - 3rd ed., add. and reprint. - Electron.text data. (36.1 MB). - Moscow: Publishing group
"GEOTAR-Media", 2011. - 240 p.
4. Alyautdin, R.N. Pharmacology [Electronic resource]: textbook for secondary Prof. education / R. N. Alyautdin, N. G.
Preferansky, N. G. Preferanskaya. - Electron.text data. (44.6 MB). - M.: Publishing Group "GEOTAR-Media", 2010. -704
p.
5. Harkevich, D. A. Pharmacology [Electronic resource]: textbook-Electron. text data. (62.1 MB). - M.: Publishing house
of the group "GEOTAR-Media", 2010. - 752 p.
Laboratory physical resources
Special programs
Journals (electronic journals)
Literature In Russian:
Main:
1. Pharmacology: textbook / ed. by R. N. Alyautdin-M: GEOTAR-Media, 2013. -832 +e-mail.
2. Kopasova V. N. Pharmacology: textbook.manual/V. N. Kopasova. - M.: Eksmo, 2011. - 352 p.
3. Harkevich D. A. Fundamentals of pharmacology: textbook. - M.: GEOTAR-Media, 2015. - 720 p.
4. Alyautdin R. N. Pharmacology: textbook. - M.: GEOTAR-Media, 2014. - 704 p. :
Additional information:
1. Pharmacology of antimicrobial agents: textbook.manual / T. A. Muminov. - Almaty: Letter Print. Kazakhstan, 2016. -
784 p. -
2. Mashkovsky M. D. Medicinal products. 16. - e edition. pererab., add. and ispr. M. New Wave. 2017. – 1216 p.
3. Pharmacology:guide to laboratory classes: studies. manual / ed. by D. A. Harkevich. - 6th ed., ispr. and add.; Rec.
educational and methodological association for medical and pharmaceutical sciences. education of Russian universities. -
Moscow: GEOTAR-Media, 2014. - 512 p.

4. Fundamentals of pharmacology with a recipe: textbook / M. Z. Shaidarov [et al.]. - Astana: Aknur, 2014. - 406 p.
5.Ormanov N. Zh. Pharmacological reference book of medicinal products (classification, nomenclature, mechanism of
action and indications for use): textbook.- methodical manual /SKGFA. -; Approved by the Academic Council of the
SKGFA. - Almaty: Evero, 2013. - 138 p.
In English:
Main:
1. Katzung , Bertram G.Basic and Clinical Pharmacology [Text] : textbook / Katzung Bertram G. - 14 nd ed. - [S. l.] :
McGraw-Hill education, 2018.
2. Goodman end Gilman's , A. The Pharmacological Basis of Therapeutics [Text] : textbook / Goodman & Gilman's A. ;
editor L. L. Brunton . - 13 nd ed. - New York : McGraw-Hill Education, 2018.
12. Discipline Policy
1. Be active in practical classes;
2. Be able to work in a team;
3. Have an idea about the topic of the upcoming lecture, be ready for feedback at the lecture;
4. Must perform tasks daily according to the schedule of lectures, practical classes and classes of independent work of students with a teacher and
independent work of students
5. In the absence of activity and failure to complete the task, penalties are applied and the score on the practical lesson is reduced;
6. Must participate in discussions, complete individual and group assignments, research, and other resources;
7. Do not miss classes without a good reason;
8. Have a neat appearance;
9. Be active in practical classes;
10. Don't be late for classes;
11. Keep the workplace clean.
At the DOT
1.It is recommended that the student has the necessary technical attitude (laptop, smartphone)
2. Have a stable internet connection
3. Pre-installed communication programs ZOOM, Webex, etc.
4. Be able to get in touch during distance learning according to the schedule
5.Timely check the availability of tasks on the Platonus AIS platform
6. Must keep track of the final dates of delivery of tasks;

7. Perform and send completed tasks on time via the Platonus AIS platforms, Mail.ru. Whatsapp in the allotted time period.
If you miss each lecture class, the score of the boundary control is reduced by 1 point, if you miss each class of the SRSP, the score for
The SRO is reduced by 2 points. The rating of admission to the exam consists of the average score of the practical lesson, the SRS, and the
boundary control
The final rating of admission to the exam in the subject must be at least 50 points (60%).
13. Academic policy based on the moral and ethical values of the Academy
Academic policy based on the moral and ethical values of the Academy
Understanding the importance of the principles and culture of academic integrity that express the integrity of the student when performing written
work, answering exams, in research, expressing their position, in relationships with teachers, students and administration.
Final control
The final score is calculated automatically based on the average score of the current control, the average score of the boundary controls, and the score
of the final control:
Final score (100 %) = Admission rating (60 %) + Final control
(40 %)
Admission rating (60 %) = Average score of boundary controls (20 %) + Average score of current controls (40 %)
Average score of boundary controls =
Boundary control 1 + Boundary control 2
Average score of the current control = the arithmetic average of the current scores, taking into account the average score on the SRO, incentive and
penalty points
Final score (100%) = RC cp x 0.2+Dac x 0.4+IG x 0.4
Rsr-average score of boundary controls
Tsr - average rating of the current control
IR-evaluation of the final control
14. Approval and revision
Date of approval Protocol No. ___ Full name of the head Signature
Date of approval Protocol No. ___ Full name of the Chairman Signature
of the KOP
Date of approval Protocol No. ___ Full name of the head Signature

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Кафедра фармакологии, фармакотерапии и клинической фармакологии 044-41/

Рабочая программа дисциплины (Силлабус) Образовательная программа «Общая медицина» 1стр. из 32

Department of "Pharmacology, Pharmacotherapy and Clinical Pharmacology"

1. General information about the discipline

3. Summative assessment form

5. Final learning outcomes (the result of learning the discipline)

Wee Topic name Synopsis The result of Number Forms/methods/

drugs in pregnant women.

from the pharmacy of medicines.

2 Lecture. Means of an oppressive type of RL 1 1 Overview Feedback

Local anesthetics. Definition.

of poisoning. The use of

Age-related aspects of the use of drugs. 2. Interaction of drugs. Prevention of

adrenoreceptors, their subtypes.

Irritating agents. Expectorants of reflex effects.

teacher Indications for use. Side effects. Journalclub) Journalclub)

different chemical structures.

agents. groups.Indications and

drugs of different groups.

Anti-tuberculosis drugs. Anti-spirochete mechanism of antitubercular action groups calculation,

Possible complications and their prescribing

Antipsychotic drugs. Antipsychotics

(group call Wathsapp, Zoom, Webex, Skype, etc.).

7.Thomson Reuters (Web of science) www.webofknowledge.com

Moscow: GEOTAR-Media, 2014. - 512 p.

6. Must keep track of the final dates of delivery of tasks;

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