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Introduction
Nonkeratinizing squamous cell carsinoma of thymus (type c thymoma) derived from thymic
epithelial cells is a rare case but mostly aggressive, easily metastasized cancer with very poor
prognosis. The incidence of type c thymoma is 0.06% of all thymic neoplasms. The therapeutic
modality is multidisciplinary treatment such as surgery, chemotherapy and radiotherapy.
Case
A 47-year-old male hospitalized in Arifin Achmad General Hospital. Complained of
breathlessness for a week before admitted to hospital, right chest pain, swollen of the neck and
right hand for a month. Mass found at region lymph node at colli dextra size 7x4x2 cm soft
consistency and no pain. His blood counts leukocytosis and increased of tumor marker test
(CEA). From the Bronchoscopy found dorsolateral encouragement at the right upper lobe. CT
scan revealed solid inhomogenous mass at anterior mediastinal, invasion to sternum and
superior vena cava. Histopathological result from core needle biopsy is nonkeratinizing
squamous cell carsinoma of Thymus. The patient received radiation therapy and systemic
chemotherapy by using carboplatin and paclitaxel regiments but exploratory thoracotomy was
not performed.
Disscusion
Diagnosis of type c thymoma is ultimately made by histology from core needle biopsy.
Debulking surgery was not performed because the patient identified at an advanced stage.
Conclusion
Type c thymoma requires special attention because it is mostly found at an advanced stage.
Keywords
Anterior mediastinal, type c thymoma, core needle biopsy
DATA PENULIS