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Oxytocin Drug Overview and Guidelines

Oxytocin is a hormone used to induce labor or strengthen uterine contractions. It can be used to control bleeding after childbirth or stimulate contractions in incomplete miscarriages. Oxytocin is contraindicated in cases of hypertension, prior uterine rupture, or active genital herpes. Potential side effects include changes in heart rate and arrhythmias, while adverse reactions range from uterine rupture to premature ventricular contractions.

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klirt carayo
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64 views2 pages

Oxytocin Drug Overview and Guidelines

Oxytocin is a hormone used to induce labor or strengthen uterine contractions. It can be used to control bleeding after childbirth or stimulate contractions in incomplete miscarriages. Oxytocin is contraindicated in cases of hypertension, prior uterine rupture, or active genital herpes. Potential side effects include changes in heart rate and arrhythmias, while adverse reactions range from uterine rupture to premature ventricular contractions.

Uploaded by

klirt carayo
Copyright
© © All Rights Reserved
We take content rights seriously. If you suspect this is your content, claim it here.
Available Formats
Download as DOCX, PDF, TXT or read online on Scribd

Name: Carayo, John Clirt A.

Drug Chart
Drug Category
Drug Name(s)
Oxytocin

Generic Name: Synthetic oxytocin


Brand Name: oxytocin injection

Contraindications Interactions

 Hypertensive to drug when  Acetylsalicylic Acid


vaginal delivery (aspirin)
 Prior Uterine Rupture  Adrenalin (epinephrine)
 Active Genital Herpes  Ativan (lorazepam)
 Fetal Distress  Benadryl
(diphenhydramine

Pharmacokinetics Pharmacodynamics
Absorption: Parental Injection Action

Distribution: Distributed throughout the Onset: Oxytocic


extracellular fluid, small amounts may enter
the fetal circulation Peak: Induced by 4 and 8 mU of synthetic
oxytocin
Metabolism: Metabolized rapidly in the
kidneys and liver, Oxytocin's plasma half-life is Duration: Approximately 40 minutes for
between 1 and 6 minutes oxytocin to reach steady-state concentrations
in the plasma after parenteral administration.
Elimination: is rapidly removed from the
plasma by the liver and kidney.

Therapeutic Effects

Oxytocin is a hormone that is used to induce labor or strengthen uterine contractions, or to


control bleeding after childbirth. Oxytocin is also used to stimulate uterine contractions in a
woman with an incomplete or threatened miscarriage.
Side Effects Adverse Reaction

 Slow heart rate.  Severe


 Fast heart rate.
 Uterine Rupture
 Cervical Laceration
 Premature ventricular complexes and other  Postpartum Hemorrhage
irregular heartbeats (arrhythmias)  Intracranial Bleeding
 Retinal Hemorrhage
 Permanent central nervous system (CNS) or  Pulmonary Edema
brain damage, and death secondary to
suffocation.
 Moderate
 Neonatal seizure.
 Uterine Contractions
 Neonatal yellowing of skin or eyes (jaundice)  Hematoma
 Bleeding
 Fetal death.  Hypertension
 Fetal Bradycardia
 Premature Ventricular Contractions (PVCs)
 Blurred Vision
 Jaundice

 Mild

 Vomiting
 Nausea

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