University of Narowal

Course Outline

16 Week Plan
Spring 2020
(BS)

Department of Zoology

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Contents
Department of Zoology......................................................................................................................................1
Bioinformatics Theory.......................................................................................................................................3

Bioinformatics Theory
Program BS Zoology
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Course Code ZOO-426 Course Title Bioinformatics Theory
Course Type Compulsory (Major) Session 2016-2020
Credit Hours 2 Pre-requisite Complete Theme of
Bioinformatics
Course Ms. Amber Khalid Semester Spring 2020 / 8th
Instructor Morning
Email Address zoology.amber@uon.edu.pk Contact 03161483331
Introduction Bioinformatics is an applied science that uses computer programs to
access biology databanks to make inferences about the information
contained within the data archives. The purpose of this course is to
introduce undergraduate students to learn techniques used in
bioinformatics and ensure that they master in the technical skills necessary
to be competitive in the market. Before getting deep in to the subject, as
the starting steps, Students will learn a little bit about biology; genetics
and genomics to be specific. This will include studying about basic
terminologies and then will learn briefly about genes, DNA, RNA, protein
structures, various databases and tools etc. This course is comparatively
new subject but modern biological and medical research and development
cannot be done without bioinformatics. Today’s job industry is full of
vacancies for people with skills in bioinformatics. Major pharmaceutical,
biotech and software companies are seeking to hire professionals with
experience in bioinformatics where they will be working with huge
amounts of biological and health care information. A major application of
bioinformatics can be found in the fields of precision
medicine and preventive medicine. Precision medicine consists of health
care techniques customized for individual patients, including treatments
and practices. Rather than treating or curing diseases, precision medicine
focuses of developing measures to prevent diseases.
1. An introduction to bioinformatics
Aims and 2. To develop awareness about fundamental bioinformatics databases
3. Information on the tools used to compute solutions to those
Objectives
problems, and the theory upon which those tools are based
Text Book 1. Rastogi, S.C., Mendiratta, N., Rastogi, P. (2011)
Bioinformatics Methods and Applications: Genomics,
Proteomics and Drug Discovery. PHI publishing.
2. Westhead, D.R., Parish, J.H., Twyman, R.M. (2003)
Instant Notes on Bioinformatics. Viva Books Private
Limited.

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1. Pevsner, J. (2015) Bioinformatics and Functional

Reference Books / Genomics. 3rd Edition. Willey-Blackwell.

2. Gibas, C. and Jambeck, P. (2001) Developing
Web resources/
Bioinformatics Computer Skills. O’Reilly publishers.
Research papers 3. Krane, D.E. and Raymer, M.L. (2002) Fundamental
Concepts of Bioinformatics. Benjamin Cummings
Websites 1. http://www.ncbi.nlm.nih.gov
2. http://www.ebi.ac.uk
3. http://www.rcsb.org
4. http://www.ensemble.org

Assignment/ Quiz/Projects/ Mids. Finals

Assessment presentations
Criteria 5 marks activity every week

 GAIN an understanding of the basic concepts of Bioinformatics.

 EXPLAIN the basics of bioinformatics and computational biology.
Learning out
 To USE bioinformatics search tools on the internet for mining
Comes
data, pairwise and multiple sequence alignments and predict
protein structures
Lecturing / Quizzes / Assignments / Report Writing / Guest
Teaching and Speakers / Presentation / Practical Activitise
learning
methodology

Sixteen Week Plan

Week Lectur Credit Topic Activities ( Critical Lab(s) if
e Hors thinking) , case applicable
study
Quiz,
Presentation,
Assignment,
Project, etc.)
1 1 Introduction to 10 marks activity
*Classes Class 1 Credit Bioinformatics will be given every
already already Hour week
held held
2 1 Credit Scope of bioinformatics,
Class Hour Aims of bioinformatics,
already disciplines related to

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bioinformatics, major tasks
held involved in bioinformatics
analysis
1 Credit Data and types of data, data
1
Hour acquisition, useful websites
2
Data and types of data, data
acquisition, useful websites
2 1
Part 2

1 Credit Bioinformatics Tools (Part1)

1
Hour
3 Bioinformatics Tools (Part2)
2 1 Credit
Hour
3 Bioinformatics (Part 3)
1
Makeup
Major DNA databases
around the world, NCBI,
1 Credit BOLD, DDBJ Major protein
1
Hour databases in the world,
protein sequence
databases(Part 1)
protein structure databases
Non sequence databases,
1 Credit
2 pubmed, pubmed health,
4 Hour
OMIM (Part 2)

Searching sequence
3 databases
Makeup 1 b. FASTA format
Class

1 Credit Databases (Part 3)

1
5 Hour
2 1 Data retrieval
1 Credit BLAST ,Introduction, Types
1
Hour and uses etc
Primer and probe, qualities of
6
1 Credit primer, general rules , primer
2
Hour designing Websites used for
primer designing
1 Credit Discussion/ Revision
7 1
Hour
Assignments/ppt/Discussion/
2 1
Revision

8 MID TERM EXAMINATION

9 1 1 BLAST ,Introduction, Types

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and uses etc
1 Credit Genetic and linkage
2
Hour mapping, physical mapping
1 Credit Mapping, physical mapping
1
Hour Gene family
1 Sequence Alignment
2
10
1 Sequence Alignment (part 2)
3
Makeup
Phylogenetic Analysis:
1 Credit unrooted tree and
1
Hour Phylogenetic methods, tree
(Part I)
Phylogenetic Analysis:
unrooted tree and
11 2 1
Phylogenetic methods, tree
(Part II)

3 Phylogenetic Analysis:
1
Makeup Introduction, interpretation,
rooted
Terminology, comparison of .
1 Credit
1 methods, software Related to
Hour
Phylogenetic analysis
12 Human Genome Project
2 1

Multiple Sequence
1 Credit Alignment:
1
Hour a. Introduction, tools for
MSA, uses and importance
13 Multiple Sequence
Alignment:
2 1 a. Introduction, tools for
MSA, uses and importance
(Part 2)
Sequence Alignment:
1 Credit Importance and significance
1
Hour of alignment, methods for
sequence alignment
14
Sequence Alignment:
Importance and significance
2 1
of alignment, methods for
sequence alignment (Part 2)
15 1 1 Discussion/ PPt/Assignments
2 1 Discussion/PPt/Assignments

Total credit Hours=32

16 Final Term Examination
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`Note: *Two classes will be conducted in one Week classes (02 Credit Hours has already been
conducted).
*There will be makeup lectures/classes of 1 Credit Hour in 3rd, 4th, 10 and 11 week.

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