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  • Adme Uas

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    Galan Rizqi Yanuar
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    This document contains predictions for various ADME/Tox properties of a compound, including that it is a weak inhibitor and substrate of CYP2D6 and CYP3A4, has low blood-brain barrier penetration, moderate intestinal absorption and skin permeability, and is moderately soluble in buffer and water.

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    adme uas

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    This document contains predictions for various ADME/Tox properties of a compound, including that it is a weak inhibitor and substrate of CYP2D6 and CYP3A4, has low blood-brain barrier penetration, moderate intestinal absorption and skin permeability, and is moderately soluble in buffer and water.

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    © All Rights Reserved
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    10 views1 page

    Adme Uas

    Uploaded by

    Galan Rizqi Yanuar
    This document contains predictions for various ADME/Tox properties of a compound, including that it is a weak inhibitor and substrate of CYP2D6 and CYP3A4, has low blood-brain barrier penetration, moderate intestinal absorption and skin permeability, and is moderately soluble in buffer and water.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    of 1

    ADME – PreADMET | Prediction of ADME/Tox

    ID Value
    BBB 0.0199556
    Buffer_solubility_mg_L 10.4808
    Caco2 22.2513
    CYP_2C19_inhibition Non
    CYP_2C9_inhibition Non
    CYP_2D6_inhibition Inhibitor
    CYP_2D6_substrate Weakly
    CYP_3A4_inhibition Non
    CYP_3A4_substrate Weakly
    HIA 95.705770
    MDCK 2.96991
    Pgp_inhibition Non
    Plasma_Protein_Binding 53.123894
    Pure_water_solubility_mg_L 344.283
    Skin_Permeability -3.67838
    SKlogD_value 0.789620
    SKlogP_value 2.128720
    SKlogS_buffer -4.605850
    SKlogS_pure -3.089330

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