Joddaram Front

D
JO
Natural Support for Musculoskeletal discomfort JODDARAM
Reduces inflammation by acting on inflammatory mediators
Enhances cellular immunity by reducing oxidative stress
Reduces cartilage damage significantly & improves quality of Life
Acts as a natural antinociceptive, analgesic; safe on gastric mucosa
Reduces periarticular stiffness due to muscle relaxant activity

Ashwagandha:
Withania somnifera:
COMPOSITION
Each tablet contains standardized extracts of: A Natural replacement for Glucosamine
Eshwarmool Aristolochia indica 75 mg sulphate which reduces inflammation and
Mahishakshi Guggulu Balsamodendron mukul 40 mg
Pawar Cassia tora 75 mg cartilage damage significantly. 1
Anantmool Hemidesmus indicus 115 mg
Ashwagandha Withania somnifera 70 mg
Muchkund Pterospermum acerifolium 40 mg
Kuchala Sudha Strychnosnux vomica 10 mg
Nirgundi (Samhalu) Vitex negundo 75 mg
1.SumantranVNet.El,PhytotherRes.2008Oct;22(10):1342-8
 Joddaram Back

D
JO

JODDARAM
Plausible Mode of Action:
Natural Support for Musculoskeletal discomfort

Antiinflammtory -Mahisakshi Guggul1, Nirgundi 2, Muchkund3 and

Ashwagandha 4
Cellular immunity - Ishwari mool5
Antinociceptive and muscle relaxant: Anantamool6 and Parwar7
Analgesic:Nirgundi 8
Chondroprotection: Ashwagandha 9
JODDARAM, a comprehensive remedy for osteo-arthritis, rheumatoid arthritis, ankylosing spondylitis
and chronic musculoskeletal pain

Clinical Trial:
Joddaram is effective in reducing the severity of pain and signs of inflammation
associated with arthritis as evidenced by the randomization trial the mean of
tender joint value (p <0.001), swollen joint (p<0.001) and mean VAS score
(p<0.001). This drug also showed significant improvement in improving disability
associated with on chronic arthritis like osteoarthritis, rheumatoid arthritis,
psoriatic arthritis, spondyloarthritis, and other rheumatological conditions.

Singh V.B. et,el., Effect of Herbal medicine JODDARAM in arthritis patients -

Randomized controlled study, S.P. Medical College, Bikaner, 2008.

1-2 Tablets twice daily after meals with
water or as directed by physician.
1.Mahisakshi Guggul a) GUJRAL ML et EL, Indian J Physiol Pharmacol. 1960 Oct;4:267-73. b) Kimura I et EL,Bioorg Med Chem Lett. 2001 Apr 23;11(8):985-9. 2.Nirghundi a) Tandon VR et El,Indian J Med Res. 2006
Oct;124(4):447-50.(leaf extract) b) Dharmasiri MG et EL,J Ethnopharmacol. 2003 Aug;87(2-3):199-206.(fresh leaves)(common referece for analgesic and anti-inflamatory) c) Chawla AS et EL,J Nat Prod. 1992
Feb;55(2):163-7.(seeds) 3.Muchkund Kharpate et El,Indian Journal of Phharmaceutical Sciences (2007) 69, 6, 850--852 (hepatoprotective activity) 4.Ashwagandha Sumantran VN et. El, Phytother Res. 2008
Oct;22(10):1342-8 5. Ishwari mool Metria medica of india,Kulkarni AD.ed 2005 6.Anantamool Verma PR et EL,J Ethnopharmacol. 2005 Nov 14;102(2):298-301 7. Parwar Chidume FC et EL,J Ethnopharmacol. 2002
Jul;81(2):205-9.8.NirghundiZhengCJetEL,Phytomedicine.2009Jun;16(6-7):560-79.AshwagandhaSumantranVNetEL,JBiosci.2007Mar;32(2):299-307.