Bio 307 Biochemistry I

2021/2022-Fall semester

Text book: Lehninger Principles of Biochemistry

Course Content:
Introduction -(18th October.)

I. The Major Chemical Constituents of Living Organisms. Main Elements, Chemical Bonds and
their Characteristics - (22nd October) (2 hrs)

II. Properties of Water and Aqueous Solutions - (25th October) (2 hrs)

III. Proteins, Structure and Functions - (29th Oct., 1st and 5th Nov.) (6 hrs)
a) Amino acids; classification, chemical structures and properties
b) Peptides; peptide bond and properties
c) Proteins; properties, functions, covalent structure of polypeptides, techniques for
sequence analysis, secondary, tertiary and quaternary structures

IV. Enzymes - (8th, 12th, 15th Nov.) (6 hrs)

a) Classification, catalytic power and specificity
b) Enzyme Kinetics and Inhibition
c) Reaction mechanisms
d) Regulatory Enzymes

V. Methods of Separation, Purification and Characterization - (19th, 22nd, 26th Nov.) (6 hrs)

1st Exam – Parts I-IV: November 30th, 2021

VI. Carbohydrates – (3rd, 6th Dec.) (4 hrs)

a) Structures, stereoisomers
b) Chemical reactions
c) Oligo and polysacharides, structure and functions

VII. Lipids – (10th, 13th Dec.) (4 hrs)

a) Structure of fatty acids
b) Classification of lipids, glycerides
c) Phospholipids
d) Lipids with specific biological activities; Steroids, cholesterol, fat soluble vitamins and
eicosanoids

VIII. Membrane Structure – (17th, 20th Dec.) (4 hrs)

a) The fluid mosaic model
b) Molecular constituents of membranes
c) Solute Transport across membranes

IX. Signal Transduction - (24th and 27th Dec., 3rd and 7th Jan.) (8 hrs)
a) Hormones
b) Receptor tyrosine kinases
c) G-proteins
d) Phosphoinositide pathway
2nd Exam – Parts V-IX: January 11th, 2022

X. Nucleic Acids – (10th, 14th Jan.) (4 hrs)

a) Purine and pyrimidine bases, chemical properties
b) Nucleosides – Nucleotides
c) Primary structures of nucleic acids

XI. Bioenergetics – (17th Jan.) (2 hrs)

a) Principle of bioenergetics
b) Laws of thermodynamics
c) Free energy concept
d) High energy phosphate containing compounds
e) Biological oxidation-reduction reactions
f) Universal electron carriers; Cofactors and proteins

Course Hours :
Monday: 15:40-17:30 YP A3 and Zoom (2 hrs)
Friday: 15:40-17:30 YP A3 and Zoom (2 hrs)

Zoom Link:

Topic: BIOL 307

Join Zoom Meeting

https://zoom.us/j/95247627326?pwd=ZFBJbmNPVnBXRkQwQ3pFUmkyUUxMQT09

Meeting ID: 952 4762 7326

Passcode: 476092

Exams:

1st Exam (30%) – Parts I-IV: November 30th, 2021

2nd Exam (30%) – Parts V-IX: January 11th, 2022

Final (40%) Jan., 2022-date to be announced