Glomerulonephritis

vs. Nephrosis

Glomerulonephritis Nephrosis (Nephrotic syndrome)

- inflammation & scarring of the kidney - Inflammation & scarring
- Key difference HIGH massive amounts
Cause:
of protein dumped into urine
Infection - typically Strep infection
Cause:
and usually gone in 14 days
Autoimmune diseases like Lupus where the
body attacks itself
Triggers - 4 S’s initiates an immune response
- S - stress
- S - sickness or sepsis (infection)
Signs & Symptoms - S - smoking
- S - sun (hot temps)
- LESS protein loss
UA: lower Proteinuria Signs & Symptoms
- Recent Strep infection Low Albumin
(Key assessment) MORE protein loss
- Fever UA: HIGH Proteinuria

Albumin
- Blood Labs: WBC HIGH Blood Labs: Low Albumin
“Hypoalbuminemia”
Treatment:
Memory trick
- Treat cause INFECTION - Nephrotic Syndrome
- Educate - finish all antibiotics - Nasty protein loss
- Limit Protein NCLEX TIP
- Meds -Antihypertensives Deadly Complication
- A - Ace & Arbs Lisinopril

Renal Failure & HTN Crisis!

- “-pril” - Lisinopril
- “-sartan” - Losartan Report key signs:
- B - Betas - Headache & Mental Status Changes
LOSARTAN
- C - CCB - Nausea & Vomiting !
!
- D - Diuretics - “-ide” - Oliguria - NO or low urine output !

- New, Sudden, Rapid Weight Gain

- Loops “FurosemIDE”
- Thiazide “HydrochlorothiazIDE”
Treatment:
Both are potassium wasters - < 3.5

- Increase Protein NCLEX TIP

so watch out for hypokalemia Potasssium

K+ - Treat cause & remove trigger

(potassium less than 3.5) - Steroids “-sone” Prednisone