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Epilepsy & Behavior 103 (2020) 106854

Contents lists available at ScienceDirect

Epilepsy & Behavior

journal homepage: www.elsevier.com/locate/yebeh

Special Communication

Telemedicine in epilepsy: How can we improve care, teaching,


and awareness?
Najib Kissani a,b,⁎, Yilédoma Thierry Modeste Lengané c, Victor Patterson d, Boulenouar Mesraoua e,f,
Eliashiv Dawn g, Cigdem Ozkara h, Graeme Shears i, Harmiena Riphagen j, Ali A. Asadi-Pooya k, Alicia Bogacz l,
Ismael El Aarrouni m, Pradeep Pankajakshan Nair n
a
Commission of Telemedicine of the University Teaching Hospital Mohammed VI, the University Cadi Ayyad of Marrakesh, Morocco
b
Medical Research Center & Neurology Department, University Teaching Hospital Mohammed VI, Marrakesh, Morocco
c
Department of Neurology, University Teaching Hospital Yalgado Ouédraogo, Ouagadougou, Burkina Faso
d
University College London, UK
e
Hamad Medical Corporation, P.O. Box 3050, Doha, Qatar
f
Weill Cornell Medical College, Qatar, Neurology Department, P.O. Box 3050, Doha, Qatar
g
UCLA Seizure Disorder Center, UCLA Department of Neurology, CA, USA
h
Istanbul University, Cerrahpasa Medical Faculty, Department of Neurology, Division of Clinical Electrophysiology, Istanbul, Turkey
i
Epilepsy Foundation, Australia
j
Epilepsy Namibia (wo292), Namibia
k
Jefferson Comprehensive Epilepsy Center, Department of Neurology, Thomas Jefferson University, Philadelphia, PA, USA
l
Institute of Neurology, Epilepsy Surgical Program, Universidad de la República, Montevideo, Uruguay
m
University Teaching Hospital Mohammed VI, Marrakesh, Morocco
n
Department of Neurology, JIPMER, Pondicherry, India

a r t i c l e i n f o a b s t r a c t

Article history: Telemedicine (TM) is the use of telecommunications' technologies to provide medical information and services.
Received 1 September 2019 Telehealth (TH) permits broader and psychosocial support for patients and their families. We aimed to highlight
Revised 8 December 2019 the importance of the use of TH for all aspects of epilepsy, either for the scientific aspects (e.g., research, educa-
Accepted 11 December 2019
tion, care, management, etc.) or for the social matters (e.g., education, sensitization, association support, etc.).
Available online 6 January 2020
There is a deep gap in knowledge and use of TH in the developing and developed countries.
Keywords:
Epilepsy is a condition responsible for 1% of the global burden of disease. More than 50 million people have ep-
Telemedicine ilepsy, and barriers to care include shortage of human resources, medical facilities, and resources. Eighty (80) per-
Epilepsy cent of people with epilepsy (PWE) live in low- and middle-income countries. Telehealth has the potential of
Education addressing limited resources and improving access to PWE across the globe.
Scientific © 2019 Elsevier Inc. All rights reserved.
Social
Care

1. Introduction refers to a broader scope of remote healthcare services than TM. In


USA, TM refers specifically to remote clinical services, while TH can
1.1. Telemedicine refer to remote nonclinical services.
As such, TM and TH encompass the whole range of medical activities
Telehealth (TH) is the use of a technology-based virtual platform to including diagnosis, treatment and prevention of disease, continuing
deliver various aspects of health information, prevention, monitoring, education of healthcare providers, teachers, support workers, and con-
and medical care. The fastest growing sector of healthcare, TH's largest sumers, and research and evaluation [3].
segment, is telemedicine (TM) [1]. Telemedicine is the use of telecom- Telehealth episodes may be classified on the basis of the following:
munications' technologies to provide medical and psychosocial infor-
✓ The interaction between the groups and either prerecorded (also
mation and services [2]. Telehealth is different from TM in that it
called store-and-forward or asynchronous) or real-time (also called
synchronous) and
⁎ Corresponding author at: Neurology Department, Razi Hospital, University Teaching
Hospital Mohammed VI, Marrakesh 40080, Morocco.
✓ The type of information being transmitted, including data and text,
E-mail address: najibkis@gmail.com (N. Kissani). audio, still images, and video pictures.

https://doi.org/10.1016/j.yebeh.2019.106854
1525-5050/© 2019 Elsevier Inc. All rights reserved.
2 N. Kissani et al. / Epilepsy & Behavior 103 (2020) 106854

1.2. Telemedicine in epilepsy 4.1. Professionals

Epilepsy is a disease of the brain defined by any of the following con- Neurologists and other caregivers of first, second, and third level
ditions: (1) at least two unprovoked (or reflex) seizures occurring N24 h health centers can be connected through TM. The experienced neu-
apart, (2) one unprovoked (or reflex) seizure and a probability of fur- rologists or epileptologists of tertiary level centers can be contacted
ther seizures similar to the general recurrence risk (at least 60%) after through TM in case of diagnostic difficulties at the lower levels of
two unprovoked seizures, occurring over the next 10 years, and (3) di- health centers.
agnosis of an epilepsy syndrome [4]. Through TM, a network of communication can be set up between
Epilepsy is one of the most common neurological disorders with its physicians at three levels with experts within and outside countries. It
unique set of challenges. This already difficult situation can be exacer- can consist of experts, epileptologists, general neurologists, neuroradi-
bated by many factors including poverty, lack of seizure control, trans- ologists, neurosurgeons, psychiatrists, neurogeneticists, GPs, psycholo-
portation issues due to long distances, and the stigma that still gists, EEG technicians, and nurses involved in PWE care.
surrounds epilepsy [5].
Telehealth has the potential to be utilized in patient management, 4.2. Persons with epilepsy and their families
education of people with epilepsy (PWE) on epilepsy, and psychosocial
support groups and reduced through education stigmatization. It offers People with epilepsy often experience transport barriers because of
the opportunity to mitigate the barriers caused by geography or lack of withholding of driving privileges, low socioeconomic status, or fear of
mobility or resources, provided that an internet access exists. Unfortu- having seizures in public.
nately, TH is underutilized. Telemedicine and TH technologies offer the ability to receive equita-
ble access to medical, psychosocial, and educational services via
technology.
2. Objectives

4.3. Psychosocial support


The objectives of this study were as follows:

Associations of PWE both inside and outside the International Bu-


✓ To emphasize the importance of the use of TM and TH in the epilepsy
reau for Epilepsy (IBE) are benefiting from TH [11]. Telemedicine and
field, the first one in scientific and the second in social aspects;
TH enable educational and training programs to be delivered to both in-
✓ To identify the gaps in the knowledge and the use of TH in epilepsy;
dividuals and their families and to staff in education, disability, work-
✓ To optimize the use of TH in the epilepsy field for developing coun-
place, and care sectors. This education supports PWE and those
tries; and
around them to understand an individual's condition and how best to
✓ To try to simplify the TM and TH procedures for all kind of users (ex-
support them to reach their potential in life irrespective of where they
perts in epilepsy, neurologists, general practitioners (GPs), PWE,
live, provided that they have internet access.
families).
Many activities can be simultaneously carried on via audio or video
teleconferences. In addition, associations' websites, blogs or Facebook,
or any social media tool could help to increase the understanding of ep-
ilepsy in communities.
3. Why to use TM and TH in epilepsy?
5. Scope of TM and TH sessions in epilepsy
In the Mental Health Gap Action Programme (mhGAP) of the World
Health Organization (WHO), epilepsy is a priority [6]. Also, in the overall
Patient and caregiver education/support: Activities can be catered to the
policy and strategy for the attainment of health for all in the 21st cen-
specific needs of the target population (tele-education, tele-meeting,
tury, WHO recommends to integrate the appropriate use of health
telematics [7,8]. tele-sensitization, etc.).
To overcome the shortage of human resources and medical facilities, TM includes different varieties of activities such: tele-education,
the long distances either in developed countries (e.g., Canada, Australia) tele-meeting, tele-sensitization, telediagnosis, tele-emergency,
or developing countries, and the development of information technolo-
tele-treatment, tele-follow-up of any adverse effects, tele-education,
gies, TH offers an opportunity for caregivers, patients, and their families
tele-transmission (congresses and other meetings), teleconference,
to improve and disseminate knowledge and awareness about epilepsy.
tele-advice, tele-research, tele-teaching, tele-emergency (as for sta-
Telehealth has the capacity to improve the quality of epilepsy man-
agement and increase patient and caregiver satisfaction. This is espe- tus epilepticus), and finally telecast (sharing any conference or
cially important for people who are far from medical facilities. People meeting about any topic in epilepsy).
with epilepsy even in developed countries due to their limitations of
driving privileges may be unable to come to their appointments or par- 5.1. Between professionals
ticipate in support groups' activities.
We emphasize that TM and TH address access to care, not only for In developing countries or even in some underserved areas in devel-
developing countries, but also for developed countries in remote areas oped countries (USA, Canada, and Australia), there are few or no neurol-
where health professionals and facilities are not readily available. ogists, and their distribution is unequal. Telemedicine in epilepsy
In addition to the improvement in care, TM can provide an econom- facilitates rapid communication and exchange of information for educa-
ically viable response to many challenges [9,10]. tional purposes like lecturing on specific topics in epileptology, interac-
tive case discussions.

4. Who can benefit from TM and TH in epilepsy? ✓ It is feasible and cost-effective to give an informative lecture via TM
facilities as it gives opportunity to interact. The audience (neurolo-
Beneficiaries of TM include medical experts, neurologists of 1st, 2nd, gists, GPs, nurses, EEG technicians) may ask questions or make re-
and 3rd levels of health systems, GPs, and also paramedical staff (nurses, marks by Short Message Service (SMS), email, etc.
electroencephalogram [EEG] technicians). For TH, the most concerned ✓ The same video-recorded lecture may be left on website to be
are patients, their families, and associations. reached anytime by the professionals.
N. Kissani et al. / Epilepsy & Behavior 103 (2020) 106854 3

In many states of the USA (around the state of New Mexico), project 5.2. Between professionals and PWE
ECHO® (Extension for Community Healthcare Outcomes) links expert
interdisciplinary specialists with primary care providers through Telemedicine in epilepsy will help professionals to provide informa-
teleECHO™ clinics. It is a lifelong learning and guided practice model tion related to various aspects of epilepsy either live or as prerecorded
that revolutionizes medical education and exponentially increases sessions to people at different places at same time.
workforce capacity to provide best practice specialty care and reduce Telemedicine also provides the opportunity for patients to commu-
health disparities. It has been used by the American Academy of Pediat- nicate with specialists, and this will help to reduce the problem of acces-
rics to support multiple epilepsy ECHOs like the following: sibility to medical facilities for many PWE (for those with disability,
sequelae or handicap, lack of resources for travel costs). They can ex-
- quality improvement approach for healthcare professionals to learn change information related to the evolution of the disease, drugs and
and improve access to quality healthcare for children and youth with their side effects, or any other useful information (particular state as
epilepsy [12] and pregnancy for example), or send files of EEG, magnetic resonance imag-
- managing students with seizures by bringing together healthcare ing (MRI) images, videos of seizures, etc.
providers (school nurses) and subject matter experts using didactic Telehealth could also be used to assist associations in starting their
and case-based presentations, fostering an “All TEACH, ALL LEARN” activities, in preparing the legal documents for registration, and in any
approach [13]. assistance needed by patients and their families and associations'
members.

This project, ECHO, has been used in 38 countries, including resource 5.3. Between PWE
poor countries [14].
Telemedicine has the potential to increase audience size as to bridge People with epilepsy already use blog, group Facebook, and many
the gap in term of epilepsy education and training, especially in devel- other social media links to exchange data about their disease, treatment,
oping countries with limited resources (Africa, Latin America, and and all daily living problems.
South East Asia) that could benefit from e-learning [15]. Many patients use some free system of exchanging data, like audio,
The decision-making in drug-resistant epilepsy (DRE) that approxi- images, and videos, using either WhatsApp or Viber, that helps some pa-
mately concerns a third of PWE involves analysis of various clinical, ra- tients with complicated situations to overcome their affections.
diological, and EEG data by experts during patient consensus decision- We should highlight the possibility of connecting illiterate patients
making meetings. These meetings could be planned in real-time, as between themselves, or with their physicians, using mobile phone
per tele-meeting, or it could be shared in different times by all con- apps via audio recording. This is a good opportunity for patients to get
cerned specialists, as in dedicated forums or simply through email. answers to any of their questions in rural areas.
This will help in effective utilization of available meager resources par-
ticularly in developing countries. In addition, trainees in these centers 5.4. Between associations
get chance to talk to the experts and further their understanding of
the decision-making process. Telehealth can be used to exchange about activities and for social
Radiology in epilepsy is a relatively specialized area, and second or events' preparation. It also improves the building of an educational pro-
third opinion may be required to pick up lesions such as focal cortical gram for patient, parents, and general public.
dysplasia, which can be obtained in real-time if we network different In Australia, the research of the Epilepsy Foundation which has com-
centers through TM. bined a comprehensive review of published studies from the literature,
Using mobile phones, any physician can pick up an image and send it consultations of experts, and surveys identified some priorities in epi-
to a colleague or an expert by email, or easily by Viber or Whatsapp, and lepsy. Telemedicine can be used as a powerful tool for some of them:
can have an opinion in few minutes and facilitate the decision taking for
a patient in another part of the country or the world. - Improving public knowledge, awareness, and attitudes towards ep-
For the research in epilepsy field, TM will help on the following ilepsy (discrimination, disclosure);
topics like those identified by the Epilepsy Foundation in Australia: - Improving patient and family education, information, expectations,
and communication (information needs);
✓ Evaluation of innovative teaching strategies; - Employment (vocational rehabilitation programs) and access to ed-
✓ Assessment of the format and frequency of educational and training ucation; and
opportunities existing within epilepsy centers; - Quality of life issues (culture, resilience), mobility issues (inability to
✓ Identification of knowledge gaps across health professions that re- drive), and sport (social participation).
late to areas such as seizure recognition and classification, new treat-
ment options, sudden unexpected death in epilepsy (SUDEP), and
appropriate treatment modalities for specific subpopulations; The Epilepsy Foundation pointed out the need to break down the di-
✓ Development and testing of educational interventions and incen- vision between the community service organizations and the epilepsy
tives; and research community by building partnerships and working together
✓ Assessment of current attitudes and beliefs of health professionals as a whole unit to improve information and education [15].
about epilepsy and the impact of these beliefs and attitudes on
stigma and on access to and quality of care [15]. 6. What system to use for video teleconferencing?

Video teleconferencing (VTC) is a technology that facilitates the


In term of physician–nurse communication and exchange of infor- communication and interaction of two or more users through a combi-
mation, there is one use of TM to support nonphysicians to deal with ep- nation of high-quality audio and video over Internet Protocol (IP)
ilepsy which involves escalating TM as follows: first, the nurse may deal networks.
with the patient on his/her own; second, she/he may deal with him after We can choose a large range of solutions available.
a phone call to a neurologist; and finally, the neurologist may need a The 2 major ones are as follows:
video call to the patient and the nurse together. This saves a lot of The first one is the use of phone network, and the 2nd one is the sat-
physician's time [16]. ellite transmission.
4 N. Kissani et al. / Epilepsy & Behavior 103 (2020) 106854

6.1. Internet solutions desk; the patient's notes are on hand; the computer is on, with access
to relevant results and scans, etc., …; and the phone is on loudspeaker
The use of phone network (asymmetric digital subscriber line [ADSL] to maintain hands free and so other people in the room can hear; and
connection) is a digital communication technique that uses phone net- • Preparatory contact: Patients receive a courtesy call beforehand, e.g.,
work to transmit data and connect to the Internet. from a secretary, to be reassured that the consultation will happen
Within this category, we have the following different systems: (even if late). This also reassures the clinician that the patient's correct
Webex (CISCO), Zoom, Skype, Live class, “go-to-meeting”, “high-five” and preferred phone number is to hand.
and “go-to-webinar”…, etc. ✓ The opening statement: After introducing other people in the room
These software offers flexible audio and video conferencing solu- (students, etc.), the carer could ask and record in the notes who else
tions available in various plans. Each plan offers a specific capacity of is listening in at the patient's end;
work space and meeting space. They can host webinars, teach online ✓ The consultation itself: the style of consultation differs to that when
courses, and conduct online training, video demonstrations, virtual a face-to-face, for example, prolonged silences need some filling (‘uh
meetings, and video conference via internet. huh’, ‘yes’);
The basic forms are often offered as a free service for three groups. ✓ Patients worry if the call is late, so clinicians can phone early;
For more, the monthly cost varies from 5.00$ (8 groups) to 49$ (200 ✓ Take each patient in turn: patients for telephone consultation must
groups) [17–19]. have equal priority on the list;
✓ Difficult to provide written information (patients who need pre-
6.2. Satellite connection scription changes require urgent letters (or email) to their GPs);
✓ Ending the call (patients can misinterpret the mindset of a clinician
This system of connection uses satellite transmission to connect to who ends a consultation too abruptly; it seems better for the patient
the latter. It is used in isolated locations where coverage of other types to hang up first. Some clinicians advise patients to hang up when
of networks is nonexistent. Please note that both means of communica- they are ready; however, it seems sufficient just to wait a few
tion allow connection to the internet. Only the process differs. extra seconds at the end before ending the call); and
In this perspective, TM intervenes to provide support to doctors and ✓ Not picking up: sometimes, if a patient's failing to answer a planned
citizens for remote diagnosis and treatment through the satellite phone call, it equates to ‘Did Not Attend’ [22].
connection.
The satellite connection advantages are as follows:
• Low cost, The use of smartphones can help for a better communication and ex-
• Fair connection speed, change of information between patients, their families, and carers.
• Almost total geographic availability, Many phone applications exist, and the most used ones are Viber,
• Secured, and WhatsApp, Twitter, and Facebook.
• Easy implementation. We can use exchanges via forums of websites.

7.2. For VTC sessions


6.3. Backbone of digital service provided to the end user (T-1 system)

a. To agree for TM session,


This is the backbone of digital service provided to the end user (typ-
ically business) in USA today which transmits voice and data digitally at
1.554 megabits per second (Mbps), connecting centers and hospitals for
short distances (around 30 km), widely used also in India. It can be used A TM session may involve patients and/or caregivers. The TM coordi-
to carry analog and digital voice, data, and video signal [20]. nator of the proposing group or person makes the request of a sched-
uled session to all parties involved.
7. Practical aspects of TM sessions b. To ask the party who will host the session,

To start TM, there is a need to get the following:


• Video materials which need good connection (bandwidth of more This is usually the TM coordinator of the organization if it is inside an
than 100 kbits/s) and sophisticated equipment entity. But in the case of many groups session, all the parties will chose
• And nonvideo materials which need less equipment but with limited the host following their own criteria.
possibilities.
c. To send invitations,

7.1. For the nonvideo materials


Some software proposes options for the invitations, but it is often
done through emails from the TM coordinator of the host site. Many ap-
Telemedicine is possible when good connection is not available by
plications, like Zoom, Webex, …, etc., could offer more than 2 invita-
the use of mails, SMS and voice calls, emails, and other text applications.
tions, allowing more groups to be connected in same time.
Some authors already proposed in 1993 some solutions for patients
living in remote areas or in situations making it difficult to have regular d. To be on time,
meetings with the neurologist like “consultation epistulae” or “consul-
tation telephonis”. This would consist in the follow-up of patients
with epilepsy through exchange of letters or a conversation by tele- All the parties must be connected before the beginning of the session
phone [21]. as it is required in real life.
For telephone review, some following tips have been proposed and
entitled “tips for effective telephone consultations”: e. To check in advance all needed tools (computer, camera, audio, and
internet connection),
• Setting up: telephone consultation is qualitatively identical to a face- f. To make a test in advance to avoid any unexpected technical prob-
to-face consultation; the clinician should be seated at the clinic lems,
N. Kissani et al. / Epilepsy & Behavior 103 (2020) 106854 5

g. To respect time (starting and closing of the session), and Other issues, such as limited physician acceptance, social acceptance,
h. To pay attention to all ethical aspects if the session is with patients. and technical knowledge of public, have to be overcome.

10. Keys to optimize the use of TM and TH in developing countries

A TM session involving patients and/or personal health information In low- and middle-income countries (LMIC) and even in some re-
may be recorded with some following conditions: the request, accep- mote areas of developed countries, it is more difficult to get dedicated
tance by written consent between the healthcare and the patient; the video transmissions to work. Telephone, SMS, email, and apps are
integration of the recording to the patient's health record at the site; more feasible. In Morocco, we have had good experiences with
and the secure storage of recordings/photos if they were not generated WhatsApp and Viber to share information between physicians and pa-
to provide for and/or support patient care. tients to monitor medications and their side effects and address urgent
We can also exchange EEGs, photos, videos, and side effects by questions from rural physicians. We still hold the position that these ap-
smartphone applications. plications' use does not replace face-to-face consultation.
Research Ethics Committees/Boards require specific consent forms Some phone apps are developed to help nonspecialist healthcare
that are drawn up/approved and completed where research involving provider in LMIC to diagnose generalized epilepsy at first-level care [27].
patients (human subjects) is being undertaken. Always consult and ad- A tool to enable nondoctors to diagnose episodes of altered con-
here to your organizations' policy and procedure with respect to any re- sciousness as epileptic or nonepileptic was developed in Nepal. It was
cordings involving patients and/or personal health information [20]. based on an analysis of the sort of questions that comprise routine his-
TM's Legislation is already available in some countries as USA, Aus- tory taking in this situation [27]. The tool showed initial promise in a
tralia, or Switzerland), for Morocco a new law (article 101 of law 131- small population of 14 patients, and its validity had been tested in a
13 approved in its final version by the Moroccan government in May larger series of patients from India and Nepal [28].
2018) [23]. Even SMS can be useful. In Namibia, SMS is hugely important. They
have 24/7 helpline, and most contacts are by SMS. Short Message Ser-
8. Special situations vice is cheap, and for those who want to avoid stigma, they answer
name withheld SMS.
Blind people as well as illiterate people may benefit only from audio Anecdotally, Namibia reports that they had a lingering problem con-
sessions. vincing PWE to use a seizure diary to make communication with medi-
In many developing countries, like in Morocco and many sub-Saha- cal personnel effective. Complaints were that printed diaries were
ran African countries, patients who had never been in school could be expensive, a problem of illiteracy, and old-fashioned to write. In desper-
taught how to click on an audio recording. Via WhatsApp, or Viber, or ation to find a solution, they tried the EpiDiary App. Although they did
any other similar phone communication applications, the patient this on an experimental basis, they found that more people were willing
sends an audio message to his physician; the profile's photo could facil- to enter data on their phones rather than on paper. The illiteracy argu-
itate recognizing his correspondent (neurologist, pediatrician, or GP). ments disappeared, and using the App instead of a paper diary was doc-
The physician has to respond by the same format the patient is receiving umented as “it is cool”.
as to address questions. Websites of the IBE, its chapters, and active associations permit ex-
The same application procedures could be adapted on websites as changes between patient, associations, IBE, and chapters.
tutorials.
11. Collaboration
9. Cost
For all the aspects of collaboration to fight against the social conse-
Cost and reimbursement issues provide challenges to TM and TH. quences of epilepsy, TM will be a great support.
Some advocate that TM and TH should be free for patients, while others
propose to expand reimbursement for this model of care. We know that 11.1. Scientific
funding had been an important barrier to TM programs in the USA when
Medicare did not provide reimbursement for most of TM care [24]. Staffs, meetings, and tele-transmission of epilepsy conferences will
Nowadays in the US, Medicare reimbursement for TH has been updated gather many professions as to make them be more aware of advances
and covers more services (e.g., neurobehavioral status exam, depression in epilepsy.
screening) [25]. Teaching course via TM, research, and expertise mentors for young
Despite expansion of Medicare reimbursement for TH, it is unclear and less experimented health professionals.
whether and to what extent US physicians are using this capacity to
treat PWE (e.g., advance care planning, family psychotherapy, 11.2. Social
prolonged service in the office—all reimbursable for Medicare patients
—or something to this effect.). So, the system is improving each year A huge field of education of PWE is available through websites, reg-
with more services offered and clear conditions given for its use. ular sessions of TM with association for assistance and counseling.
The use of TM in epilepsy must be cost-effective if we expect sustain- For the creation of new chapters and associations, IBE can use TH for
able programs [2]. Ideally, the national healthcare system should find assisting and advising the initiators.
ways of compensation for the healthcare professionals delivering the
TM to the patients. 12. Conclusion
In Switzerland TM activities, citizens pay health insurance compa-
nies. If citizens are unable to pay, they are subsidized by their canton Telemedicine and TH provide the best opportunity to mitigate the
which pays this contribution directly to the health insurance companies. barriers caused by geography or lack of mobility or resources in deliver-
General practitioner and specialist care are covered by insurance, but ing the required care to patients with epilepsy. With TM and TH, care,
cantons provide a substantial share of hospital funding [26]. education, and support can be provided to any group, no matter
In some countries like USA and Switzerland, insurance costs includ- where they live, provided that they have internet access or at least mo-
ing TM can be charged by credit card. In France, the system is available bile phone or late on access to internet. To successfully establish a TM or
only in some health centers with various payment systems. TH program, the minimum requirements with regard to the
6 N. Kissani et al. / Epilepsy & Behavior 103 (2020) 106854

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Declaration of competing interest date: 29 November 2019.
[14] University of New Mexico. ECHO hubs and programs: global. proj ECHO. https://
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