Professional Documents
Culture Documents
www.ivis.org
International Congress of
the Italian Association of Companion
Animal Veterinarians
May 19 – 21 2006
Rimini, Italy
Next Congress :
62nd SCIVAC International Congress
&
25th Anniversary of the SCIVAC Foundation
inflammation centered around vessels leads to leakage of a cardiac function can precipitate pleural effusion when none
high protein fluid. Effusion may occur in the peritoneal was apparent prior to fluid therapy. Ideally, transudate fluids
cavity, pleural space, or both. Cats are frequently systemi- are addressed by treating the underlying cause.
cally ill with fever, hyperglobulinemia, and neutrophilia.
The effusive fluid is often clear straw or yellow in color
and viscous. Polymerase chain reaction performed on the Neoplastic effusion
effusive fluid is supportive but not diagnostic of FIP; PCR
cannot discriminate between the enteric corona and its Both dogs and cats are susceptible to thoracic neoplasia
mutated virulent form. Serology is seldom useful as it may resulting in pleural effusion although prevalence of tumor
be negative in an infected cat or positive in a cat that does type varies with species. Lymphoma and thymoma predom-
not have FIP. The gold standard method of diagnosis relies inate in cats, while carcinoma and thymoma predominate in
on tissue biopsy, but the combination of classical signal- dogs. Mesothelioma is rare in either species, and a variety of
ment and history (young cat from a cattery or shelter set- other tumor types might lead to neoplastic effusion on occa-
ting) with compatible signs, supportive laboratory findings, sion. Young FeLV + cats are more likely to have mediastinal
and typical effusion is persuasive evidence of disease. Sup- lymphoma, but most other tumor types tend to occur in old-
portive care, immune suppression, and therapies such as er animals. The effusive fluid itself may be clear, cloudy, or
pentoxifylline or IFN omega are often used in treatment hemorrhagic. Protein content is often moderately increased,
but prognosis remains very poor. as are total nucleated cell counts. The cell type varies with
the neoplastic process, but it may be very difficult to differ-
entiate carcinoma, mesothelioma, or reactive mesothelial
Transudate/modified transudate hyperplasia cytologically. Supportive therapy is combined
with appropriate chemotherapy or radiation therapy to treat
Transudates are typically due to increased hydrostatic the neoplastic condition. The prognosis for most causes of
pressure or less commonly, decreased oncotic pressure. With neoplastic pleural effusion is poor.
time the mesothelial cells become proliferative and both pro-
tein and cell content of the transudate may increase.
Increased hydrostatic pressure resulting in pleural transudate References available on request
is most often associated with heart failure. In cats, both right
and left heart failure may cause pleural effusion but in dogs
only right heart failure does so. Decreased oncotic pressure
(albumin of <1.5 g/dl) may also result in pleural transudate. Author’s Address for correspondence:
Typically, hypoalbuminemia results in more profound Leah Cohn
ascites than pleural effusion. Intravenous fluid administra- University of Missouri
tion in an animal with hypoalbuminemia or compromised College of Veterinary Medicine, Columbia, MO, USA, 65211
This manuscript is reproduced in the IVIS website with the permission of the Congress Organizing Committee