Professional Documents
Culture Documents
4BSN1
Macrophages which
Mycobacterium Tuberculosis Formation of granuloma Lung Damage formation
lies on the lung airways
goes to alveoli by mixture of of Lesion (Granuloma or
take up bacilli but
Macrophages and Bacilli Tuberculoma)
bacilli reproduce.
Medical Management
Medical Management Pulmonary TB is treated primarily with antituberculosis agents for 6 to 12 months. A prolonged treatment duration is
necessary to ensure eradication of the organisms and to prevent relapse. The continuing and increasing resistance of M. tuberculosis to TB
medications is a worldwide concern and challenge in TB therapy.
Several types of drug resistance must be considered when planning effective therapy:
• Primary drug resistance: resistance to one of the firstline antituberculosis agents in people who have not
had previous treatment
• Secondary or acquired drug resistance: resistance to
one or more antituberculosis agents in patients undergoing therapy
• Multidrug resistance: resistance to two agents, isoniazid (INH) and rifampin. The populations at greatest
risk for multidrug resistance are those who are HIV positive, institutionalized, or homeless.
Nursing Management
Promoting Airway Clearance
Advocating Adherence to Treatment Regimen
Promoting Activity and Adequate Nutrition
Preventing Spreading of Tuberculosis Infection
Tell the patient to wear a mask when outside his room. Visitors and health care personnel should also take proper precautions while in
the patients’ room.
If the patient is a woman, advise her that hormonal contraceptives may be less effective while she’s taking rifampin.
Nursing Diagnosis
Ineffective Airway Clearance may be related to thick, viscous, or bloody secretions
Risk for ineffective Therapeutic Regimen Management: risk economic difficulties
Activity Intolerance may be related to imbalance between O2 supply and demand, possibly evidenced by reports of fatigue,
weakness, and exertional dyspnea
Imbalanced Nutrition: less than body requirements may be related to inability to ingest adequate nutrients.
Risk for Infection
Risk for impaired Gas Exchange
Drug Mechanism of Action Side Effects Adverse Effects Contraindications Nursing
Considerations
Drug Name: Rifampin Interferes with Red-orange or red- hepatitis, blood Concomitant therapy Preferably take on
Generic Name: bacterial RNA brown discoloration dyscrasias, Stevens- with amprenavir, empty stomach with
Rifadin synthesis by of urine, feces, saliva, Johnson saquinavir, ritonavir; 8 oz of water 1 hr
binding to DNA- skin, syndrome, antibiotic- hypersensitivity to before or 2 hrs after
PO, IV: ADULTS, dependent RNA sputum, sweat, tears. associated colitis other rifamycins. meal (with food if GI
ELDERLY: 10 polymerase, Occasional (5%–3%): occur rarely upset). • Avoid
mg/kg/day. preventing attachment Hypersensitivity alcohol during
Maximum: 600 to DNA, reaction treatment. • Do not
mg/day. CHILDREN: thereby blocking take
10– RNA transcription. any other medications
20 mg/kg/day in without consulting
divided doses q12– physician, including
24h. antacids; must
Maximum: 600 take rifampin at least
mg/day 1 hr before antacid.
• Urine, feces,
Classification Anti- sputum, sweat, tears
Tuberculosis may
become red-orange;
soft contact lenses
may be permanently
stained. •
Assessment Diagnosis Planning Interventions Rationale Evaluation
Subjective Ineffective Airway Short-term Goal: Independent
“Nahihirapan po Clearance may be Monitor respirations indicative of After 1 hour of
akong huminga, lalo related to thick, After 1-3 hours of and breath sounds, respiratory nursing
na kapag ka viscous, or bloody Nursing intervention noting rate and distress and/or interventions client
nakahiga.” secretions client will be able to Sounds accumulation of is able to have
maintain vital signs secretions normal vital signs.
Objective
BP 110/80
BP: 130/80 Temperature - 37.2
Temperature: 37.8 Position head to open or Pulse - 85
C Long-term Goal: appropriate for maintain open RR - 20
Pulse 89 age/condition airway in at-rest Sp02 – 96
RR 24 After 4-8 of nursing or
SpO2 93 intervention client compromised. Presence of
will be able to Bloody Sputum
-Bloody and Thick maintain airway and Elevate head of
Sputum decreased viscosity bed/change position to take
(Hemoptysis) of mucus every 2 hours and prn advantage of
- Coughing gravity
decreasing
pressure on the
diaphragm and
enhancing
drainage
of/ventilation to
different lung
segment.
Encourage/provide
opportunities for rest;
limit activities
to level of respiratory Prevents/reduces
tolerance. fatigue.