Republic of the Philippines

UNIVERSITY OF EASTERN PHILIPPINES

University Town, Northern Samar
Web: uep.edu.ph Email: ueppres06@gmail.com

COLLEGE OF NURSING AND ALLIED HEALTH SCIENCES

DRUG ANALYSIS
Name of Patient: NADINE LUSTRE Date Admitted: 12/05/21 Chief Complaint: MATERNAL FATIGUE Case Number: _543_
Age: _28_ Gender: FEMALE Civil Status: MARRIED Address: UNITED KINGDOM Ward: OB WARD

NAME OF SPECIFIC INDICATION CONTRAINDICATION DRUG ADVERSE SPECIFIC NURSING

DRUG ACTION INTERACTION REACTION PRECAUTION RESPONSIBILITIES
Generic Name: Stimulates uterine Labour induction Hypertonic uterine Enhanced effect of Foetal distress, Women with Assess maternal blood
Oxytocin smooth muscle, contractions, mechanical prostaglandins. arrhythmias, borderline pressure periodically and
producing uterine obstruction to delivery, foetal Reduced therapeutic hypotension, cephalopelvic compare to normal values.
Brand Name: contractions similar distress; conditions wherein efficacy and myocardial disproportion, Report low blood pressure
Pitocin to those in spontaneous labour or vaginal increased risk of ischaemia, secondary uterine (hypotension), especially if
spontaneous labor. delivery is contraindicated hypotension with peripheral inertia, mild or patient experiences
Dosage: Stimulates mammary (e.g. significant cephalopelvic inhalation vasodilation, moderate degrees of dizziness, fatigue, or other
1-4 milliunits/minute gland smooth disproportion, foetal anaesthetics (e.g. tachycardia, QT pregnancy-induced symptoms.
via infusion muscle, facilitating malpresentation, placenta halothane, prolongation, uterine hypertension, CV Monitor signs of maternal
lactation. Has praevia, vasa praevia, sevoflurane, hypertonicity, disease (e.g. fluid and electrolyte
Route: vasopressor and placental abruption, cord desflurane, spasm, tetanic hypertrophic imbalances, such as low
Intravenous antidiuretic effects. presentation or prolapse, cyclopropane). contraction, cardiomyopathy, sodium levels
overdistension or impaired Enhanced effect of disseminated valvular heart (hyponatremia), low
Frequency: resistance of the uterus to vasoconstrictors and intravascular disease, ischaemic chloride levels
Once rupture, multiple pregnancy, sympathomimetics. coagulation (DIC). heart disease, (hypochloremia), or a
polyhydramnios, grand Increased risk of Potentially coronary artery relative increase in body
Classification: multiparity); presence of a arrhythmia with Fatal: Water vasospasm), long QT fluid (water intoxication).
Oxytocic uterine scar from previous drugs that may intoxication, syndrome, Signs include headache,
surgery including caesarean prolong QT interval. hypertension, haemodynamically confusion, lethargy,
Reference: section. Prolonged use in subarachnoid unstable states, irritability, decreased
MOSBY’S DRUG resistant uterine inertia, haemorrhage, history of lower- consciousness, and
HANDBOOK 2021 severe CV disease, severe rupture of the uterus. uterine-segment neuromuscular
pre-eclamptic toxaemia. caesarean section. abnormalities (muscle
Women ≥35 years. weakness and cramps).
Not intended for Report these signs to the
elective induction of physician or nursing staff.
labour. Pregnancy
and lactation.

Student Nurse: GABRIELLE A. MAGDARAOG Clinical Instructor: JEANETTE J. ROJO

 Republic of the Philippines
UNIVERSITY OF EASTERN PHILIPPINES
University Town, Northern Samar
Web: uep.edu.ph Email: ueppres06@gmail.com

COLLEGE OF NURSING AND ALLIED HEALTH SCIENCES

DRUG ANALYSIS
Name of Patient: NADINE LUSTRE Date Admitted: 12/05/21 Chief Complaint: MATERNAL FATIGUE Case Number: _543_
Age: _28_ Gender: FEMALE Civil Status: MARRIED Address: UNITED KINGDOM Ward: OB WARD

NAME OF SPECIFIC INDICATION CONTRAINDICATIO DRUG ADVERSE SPECIFIC NURSING

DRUG ACTION N INTERACTION REACTION PRECAUTION RESPONSIBILITIES
Generic Name: Increases electrical Epidural Hypersensitivity to amides, Increase: cardiac Arrhythmia, Pregnancy, Assess:
Lidocaine stimulation threshold anaesthesia for severe heart block, depression, bradycardia, arterial breastfeeding, • ECG continuously to
of ventricle, His- obstetric caudal supraventricular toxicity: spasms, CV children, geriatric determine increased PR or
Brand Name: Purkinje system, analgesia dysrhythmias, AdamsStokes amiodarone, collapse, oedema, patients, QRS segments; if these
Xylocaine which stabilizes syndrome, Wolff-Parkinson- phenytoin, flushing, hert block, renal/hepatic develop, discontinue or
cardiac membrane, White syndrome. procainamide, hypotension, sinus disease, HF, reduce rate; watch for
Dosage: decreases propranolol, node suppression, respiratory increased ventricular
200-300 mg (as 1% automaticity. quiNIDine agitation, anxiety, depression, ectopic beats, may have to
soln Increase: coma, confusion, malignant rebolus; B/P
hypotensive effects drowsiness, hyperthermia, • Drug levels: therapeutic
Route: —MAOIs, hallucinations, myasthenia gravis, level, 1.5-5 mcg/mL • I&O
Epidural antihypertensives euphoria, headache, weight. ratio, electrolytes
Increase: hyperaesthesia, (potassium, sodium,
Frequency: neuromuscular hypoaesthesia, chlorine)
Once blockade— lightheadedness, • Toxicity: monitor for
neuromuscular lethargy, seizures, confusion,
Classification: blockers, nervousness, tremors; if these occur,
Aminoacyl amide tubocurarine; psychosis, seizure, discontinue immediately,
monitor for adverse slurred speech, notify prescriber; keep
Reference: effects unconsciousness, emergency equipment
MOSBY’S DRUG Increase: lidocaine somnolence, nausea, nearby
HANDBOOK 2021 effects, toxicity— vomiting, metallic • Malignant
cimetidine, β- taste, tinnitus, hyperthermia: tachypnea,
blockers, protease disorientation, tachycardia, changes in
inhibitors, ritonavir dizziness, B/P, increased
Increase: paraesthesia, resp temperature
hypotension— depression and
ergots; avoid convulsions. Patch: • Respiratory status: rate,
concurrent use Bruising, rhythm, lung fields for
depigmentation, crackles, watch for
Decrease: lidocaine petechiae, irritation. respiratory depression; lung
 effects— Ophth: Conjunctival fields, bilateral crackles
barbiturates, hyperaemia, corneal may occur with HF;
ciprofloxacin, epithelial changes, increased respiration, pulse;
voriconazole diplopia,visual product should be
Decrease: effect of changes. discontinued
—cycloSPORINE • CNS effects: dizziness,
confusion, psychosis,
paresthesias, convulsions;
product should be
discontinued
•Pregnancy/breastfeeding:
use only if clearly needed;
use caution in
breastfeeding, excreted in
breast milk
Evaluate:
• Therapeutic response:
decreased dysrhythmias
Teach patient/family:
• About the use of
automatic lidocaine
injection device if ordered
for personal use
• To report signs of
toxicity immediately

Student Nurse: GABRIELLE A. MAGDARAOG Clinical Instructor: JEANETTE J. ROJO

 Republic of the Philippines
UNIVERSITY OF EASTERN PHILIPPINES
University Town, Northern Samar
Web: uep.edu.ph Email: ueppres06@gmail.com

COLLEGE OF NURSING AND ALLIED HEALTH SCIENCES

DRUG ANALYSIS
Name of Patient: KRIS AQUINO Date Admitted: 12/5/21 Chief Complaint: DIFFICULTY OF BREATHING Case Number:___234___
Age: _28_ Gender: FEMALE Civil Status: MARRIED Address: UNITED KINGDOM Ward: OB WARD

NAME OF SPECIFIC INDICATION CONTRAINDICATION DRUG ADVERSE SPECIFIC NURSING

DRUG ACTION INTERACTION REACTION PRECAUTION RESPONSIBILITIES
Generic Name: β1- and β2-agonist Anaphylaxis Hypersensitivity to Do not use with CNS effects; GI Pregnancy, Assess:
EPINEPHrine causing increased sympathomimetics, sulfites, MAOIs or disturbances; breastfeeding, • Asthma: auscultate lungs,
levels of cAMP, closed-angle glaucoma, non- tricyclics; epigastric pain; CV cardiac disorders, pulse, B/P, respirations,
Brand Name: thereby producing anaphylactic shock during hypertensive crisis disorders; difficulty hyperthyroidism, sputum (color, character);
Allerjet bronchodilation, general anesthesia. may occur in micturition with diabetes mellitus, monitor pulmonary
cardiac, and CNS • Toxicity: other urinary retention; prostatic function studies before and
Dosage: stimulation; high sympathomimetics dyspnoea; hypertrophy, during treatment
0.3-0.5 mg doses cause Decrease: hyperglycaemia; hypertension, • Vasopressor: ECG
vasoconstriction via hypertensive effects sweating; organic brain during administration
Route: α-receptors; low —βadrenergic hypersalivation; syndrome, local continuously; if B/P
IM/SUBCUT doses can cause blockers, stop β- weakness, tremors; anesthesia of certain increases, decrease dose;
vasodilation via β2- blocker 3 days coldness of areas, labor, cardiac B/P, pulse q5min after
Frequency: vascular receptors. before starting extremities; dilation, coronary parenteral route; CVP,
q10-15min product hypokalaemia. insufficiency, ISVR, PCWP during
Increase: Gangrene, tissue cerebral infusion if possible;
Classification: hypotension—α- necrosis and arteriosclerosis, inadvertent high arterial
Catecholamine blockers sloughing organic heart B/P can result in angina,
Increase: cardiac (extravasation) when disease. aortic rupture, cerebral
Reference: effects— used in addition to hemorrhage
MOSBY’S DRUG antihistamines, local anaesthetics. • Inj. site: tissue sloughing;
HANDBOOK 2021 thyroid replacement Eye drops: Severe administer phentolamine
hormones Increase: smarting, blurred with NS
dysrhythmias— vision, photophobia; • Sulfite sensitivity; may
cardiac glycosides naso-lachrymal ducts be life threatening
Drug/Herb obstruction. • Cardiac status, I&O;
• Increased Oedema, hyperaemia blood glucose in diabetes
stimulation: coffee, and inflammation of • Allergic reactions,
tea, guarana, yerba the eyes with bronchospasms (swelling
maté repeated of face/lips/eyelids, rash,
administration. difficulty breathing):
withhold dose, notify
 prescriber
Evaluate:
• Therapeutic response:
increased B/P with
stabilization or ease of
breathing, relief of
bronchospasm Teach
patient/family:
• About the reason for
product administration.

Student Nurse: GABRIELLE A. MAGDARAOG Clinical Instructor: JEANETTE J. ROJO

Republic of the Philippines

UNIVERSITY OF EASTERN PHILIPPINES
University Town, Northern Samar
Web: uep.edu.ph Email: ueppres06@gmail.com

COLLEGE OF NURSING AND ALLIED HEALTH SCIENCES

DRUG ANALYSIS
Name of Patient: KRIS AQUINO Date Admitted: 12/5/21 Chief Complaint: DIFFICULTY OF BREATHING Case Number:___234___
Age: _28_ Gender: FEMALE Civil Status: MARRIED Address: UNITED KINGDOM Ward: OB WARD

NAME OF SPECIFIC INDICATION CONTRAINDICATIO DRUG ADVERSE SPECIFIC NURSING

DRUG ACTION N INTERACTION REACTION PRECAUTION RESPONSIBILITIES
Generic Name: Prevents conversion Venous Bleeding, hypersensitivity to Increase: heparin Hypersensitivity Pregnancy, children, Assess:
Lovenox of fibrinogen to thromboembolism this product, corn, porcine action—oral reactions (e.g. chills, geriatric patients, • Bleeding, hemorrhage:
fibrin and protein (pork product). anticoagulants, fever, urticaria, alcoholism, gums, petechiae,
Brand Name: prothrombin to salicylates, dextran, asthma, rhinitis); hyperlipidemia, diabetes, ecchymosis, black tarry
Enoxaparin thrombin by NSAIDs, platelet painful, ischaemic renal disease, heparin- stools, hematuria,
enhancing inhibitory inhibitors, and cyanosed limbs; induced thrombocytopenia epistaxis, decrease in Hct,
Dosage: effects of cephalosporins, osteoporosis (in (HIT), hemophilia, B/P; HIT may occur after
15,000-20,000 U antithrombin III penicillins, long-term admin), leukemia with bleeding, product discontinuation;
ticlopidine, suppression of peptic ulcer disease, check periodically for
Route: dipyridamole, aldosterone synthesis severe thrombocytopenic sign of decreasing clots
Subcutaneous antineoplastics, leading to purpura, severe • Blood studies (Hct,
clopidogrel, SSRIs, hyperkalaemia, renal/hepatic disease, occult blood in stools)
Frequency: SNRIs, quinidine, cutaneous necrosis, blood dyscrasias, severe q3mo
12 hrly valproic acid delayed transient hypertension, subacute, • Thrombosis: monitor
Decrease: heparin alopecia, priapism, bacterial endocarditis, for increased thrombosis
Classification: action—digoxin, rebound acute nephritis; benzyl daily, in affected areas
Antigoagulant tetracyclines, hyperlipaemia; alcohol products in • Partial prothrombin time,
antihistamines, increased serum neonates/ which should be 1.5-2.5×
Reference: cardiac glycosides, concentrations of infants/pregnancy/lactatio control; for continuous IV
MOSBY’S DRUG nicotine, AST and ALT, n infusion, check aPTT
HANDBOOK 2021 nitroglycerin prolonged baseline 6 hr after initiation
Drug/Herb prothrombin time; and 6 hr after any dose
Increase: bleeding local irritation, change; use aPTT for
risk—arnica, anise, erythema, mild pain, dosing adjustments; after
chamomile, clove, haematoma or therapeutic aPTT has been
dong quai, garlic, ulceration on inj site. measured 2×, check aPTT
ginger, ginkgo, Potentially daily
feverfew, green tea, Fatal: Heparin- • Heparin-induced
horse chestnut induced thrombocytopenia (HIT):
Drug/Lab Test thrombocytopenia w/ platelet count q2-3days;
Increase: ALT, or w/out thrombosis, thrombocytopenia may
AST, INR, PT, PTT, severe haemorrhage. occur on 4th day of
potassium Decrease: treatment and resolves
platelets even during continued
treatment; HIT may
occur on the 5th-10th day
of treatment, with
platelets to 5000 mm3;
this may lead to HITT
(venous/arterial
thrombosis) even after
discontinued therapy
• Hypersensitivity: rash,
chills, fever, itching; report
to prescriber Evaluate:
•Therapeutic response:
prevention of DVT and
 pulmonary emboli;
adequate anticoagulation
based on aPTT, PTT 1.5-
2.5× control
Teach patient/family:
• To avoid OTC
preparations that may cause
serious product interactions
unless directed by
prescriber; to notify all
health care providers of
heparin use •  That product
may be held during active
bleeding (menstruation),
depending on condition • 
About subq injection
technique if self-
administered; to rotate
sites, not to inject into
irritated or broken skin
•  To use soft-bristle
toothbrush to avoid
bleeding gums; to avoid
contact sports; to use an
electric razor; to avoid IM
inj.
• To carry emergency ID
identifying product taken
• Bleeding: to report to
prescriber any signs of
bleeding: gums, under
skin, urine, stools
• To report to prescriber
any signs of
hypersensitivity: rash,
chills, fever, itching

Student Nurse: GABRIELLE A. MAGDARAOG Clinical Instructor: JEANETTE J. ROJO