Professional Documents
Culture Documents
REVIEW
PROTOCOLS and GUIDELINES
for
PERFUSION
Priming Formula
a. Clear Priming
Adult :
Crytaloid = Ringer Asetat 1500 mL
Coloid = Gelofusin 500 mL
Heparin = 5000 – 10.000 unit
Bicarbonat = 30 mEq
Manitol 20 % = 100 mL
Pediatric :
Crytaloid = Ringer Asetat 500 – 1000 mL
Coloid = Gelofusin 500 mL
Heparin = 5000 unit
Bicarbonat = 30 mEq
Manitol 20 % = 2,5 ml / Kg
b. Blood Priming
Wt < 6 Kg
PRC = (depent on additional PRC calculation)
Ringer Asetat = (depent on oxygenator and custom pack choice)
Heparin = 3500 – 4000 unit
Bicarbonat = 5 – 10 mEq
Manitol 20 % = 2,5 ml / Kg
CaCl2 = 1 mg / 1 ml additional blood
Wt 6 – 18 Kg
PRC = (depent on additional PRC calculation)
Ringer Asetat = (depent on oxygenator and custom pack choice)
Heparin = 3500 – 4000 unit
Bicarbonat = 20 mEq
Manitol 20 % = 2,5 ml / Kg
CaCl2 = 1 mg / 1 ml additional blood
Packed Red Cells, Calcium Chloride, Albumin and Tranexamic acid are included in the prime if
indicated.
Indications
Packed red cells: Predicted on bypass below 27%
Calcium chloride: Use of citrated red cells in the prime.
TA Consultant request.
Albumin Consultant request.
Methylprednisolone 20 – 30 mg/kg
Other drugs except those listed as perfusion prescribed, are added to the pump prime or during
CPB are added to the pump by the Perfusionist at the request of the surgeon / anaesthetist.
Cardioplegia Formula
1. Clear Cardioplegia
Ringer Solution = 500 mL
Cardioplegia Solution St. Thomas = 10 mL
Bicarbonat = 5 mEq
Inducsion Doses = 20 mL / Kg BB
Injecting when cross clamp on until 4 minute
2. Blood Cardioplegia
High K+
Ringer Asetat = 500 mL
Cardioplegia Solution St. Thomas = 40 mL
Bicarbonat = 30 mEq
Low K+
Ringer Asetat = 500 mL
Cardioplegia Solution St. Thomas = 20 mL
Bicarbonat = 30 mEq
3. HTK-Custadiol Cardioplegia
Inducsion Doses = 50 - 60 mL / Kg BB (Pediatric)
= 2 Liter (Adult/maximum doses)
Injecting when cross clamp onuntil 5 - 8 minute (with infusion set or cardioplegia pump set)
CPG Flow
Adult case = 250 – 350 cc/kg/mnt
Pediatric Case = 5 – 8 % from Cardiac Output
CPG Pressure
Antegrade = 50 – 100 mmHg
Retrograde = 20 – 50 mmHg
a) Bi-caval canula
FLOW N0MOR ( Fr )
SVC/IVC ( DLP ) SVC/IVC ( BARDIC )
<650 12 16 18 20
650-1000 14 18 20 24
1000-1400 16 20 22 24
1400-2000 16 20 24 24
2000-2250 20 24 26 28
2250-2250 20 24 26 28
2500-2750 24 28 28 30
2750-3000 24 28 28 30
3000-3200 24 28 30 32
>3200 28 31 32 34
5. Cardioplegia cannula.
a. Antegrade
Nomor BW (Kg)
Abocath 14 Fr < 20
ATC7 Fr 20 – 35
ATC12 Fr > 35
b. Retrograde
Nomor BW (Kg)
RC10 Fr <15
RC13 Fr 15 – 25
RC14 Fr 25 – 35
Baby RX
4 –10 800 – 1000 ¼ ¼ ¼ Baby Rx, Neonate II 400 – 500 mL
Minimax,
Liliput II
20 - 40 2000 – 3000 3/8 3/8 3/8 Cx 10 R, Pediatric 800 – 1000 mL
EOS
>40 >3000 3/8 1/2 1/2 Adult adult 1 – 1,5 L
Oxygenator
BSA = 3.207 x (Ht)3 x (Wt x 1000) 0,7285 – 0,0188 Log (Wt x 1000)
10,000
3. Square Root
BSA = Ht x Wt
3600
4. BSA Nomogram
B. Flow
Commonly used formula for cardiac surgery
1. Patients under 10 kg : Flow = weight x 150 ml/min/kg
2. Patients over 10 kg : Flow = 2400 ml/Sq.M./min
3. Blood flow rate (L/min) = Cardiac Index (L/min/m2) x BSA (m2)
D. Hemodilution
a. General dilution V1 x C1 = V2 x C2
V1 = BV
C1= Htc Pre CPB
V2= BV + Total Prime
Total prime volume varies according to types of oxygenator used
C2= Htc in CPB
c. Additional PRC
d. Phlebotomy
Phlebotomy = Hb x 5 x BB
Hb predicted x BV
or Phlebotomy = BV - Hb pre
Others Formula
Oxygenation
Correction for :
- Kalium (KCL) : ∆ K+ x BB (mEq)
3
- BE (Bicnat) : BE x BB (mEq) atau BE x BB (mEq)
3 6
- Calsium (CaCl2) : 10 mg/Kg BB (mg)
- Glucose : 0,2 grm/kg or 2 mL/Kg dextrose 10%
-Natrium : Na+ infus – Na+ serum dimana cairan dewasa 60% BB dan anak 70% BB
Cairan tubuh total + 1
- Xylocard : 1 mg/kg (bolus for VT/VF that not respond with DC shock)
- Cordarone : 150 mg (bolus for VT/VF that not respond with DC shock/xylocard )
- Largactil / Clorpomazil :
0 – 4 bulan : 3 mg/Kg BB
4 bulan – 6 tahun : 2 mg/Kg BB
> 6 tahun : 1 mg/Kg BB
Hb (adult) 7 -8 gr/dL
(Pediatric) 9 – 10 gr/dL
VO2 = Flow x [1.34 x Hb x (Art sat – ven sat) +0.003 x ( paO2 - pvO2)]
O2 consumption (VO2): 250 ml/min
Temp mL/min/m2
25 oC 29 – 34
30 oC 43 – 50
34 oC 69 – 78
37 oC 88 - 100
CHECKLIST PERSIAPAN WEANING CPB
TABEL
BSA
BERDASARKAN
BERAT BADAN
(BAYI)
FLOW FLOW
BB BSA BB BSA
2.0 2.4 2.0 2.4
2.00 0.163 0.33 0.39 3.00 0.214 0.43 0.51
2.05 0.166 0.33 0.40 3.05 0.217 0.43 0.52
2.10 0.169 0.34 0.41 3.10 0.219 0.44 0.53
2.15 0.172 0.34 0.41 3.15 0.222 0.44 0.53
2.20 0.174 0.35 0.42 3.20 0.224 0.45 0.54
2.25 0.177 0.35 0.42 3.25 0.226 0.45 0.54
2.30 0.179 0.36 0.43 3.30 0.228 0.46 0.55
2.35 0.182 0.36 0.44 3.35 0.231 0.46 0.55
2.40 0.184 0.37 0.44 3.40 0.233 0.47 0.56
2.45 0.187 0.37 0.45 3.45 0.235 0.47 0.56
2.50 0.190 0.38 0.46 3.50 0.237 0.47 0.57
2.55 0.192 0.38 0.46 3.55 0.239 0.48 0.57
2.60 0.195 0.39 0.47 3.60 0.241 0.48 0.58
2.65 0.197 0.39 0.47 3.65 0.244 0.49 0.59
2.70 0.200 0.40 0.48 3.70 0.246 0.49 0.59
2.75 0.202 0.40 0.48 3.75 0.249 0.50 0.60
2.80 0.205 0.41 0.49 3.80 0.251 0.50 0.60
2.85 0.207 0.41 0.50 3.85 0.253 0.51 0.61
2.90 0.210 0.42 0.50 3.90 0.255 0.51 0.61
2.95 0.212 0.42 0.51 3.95 0.257 0.51 0.62
FLOW
BB BSA
2.0 2.4
4.00 0.260 0.52 0.62
4.05 0.262 0.52 0.63
4.10 0.264 0.53 0.63
4.15 0.266 0.53 0.63
4.20 0.268 0.54 0.64
4.25 0.270 0.54 0.65
4.30 0.272 0.54 0.65
4.35 0.274 0.55 0.66
4.40 0.277 0.55 0.66
4.45 0.279 0.56 0.67
4.50 0.281 0.56 0.67
4.55 0.283 0.57 0.68
4.60 0.285 0.57 0.68
4.65 0.287 0.57 0.69
4.70 0.289 0.58 0.69
4.75 0.291 0.58 0.70
4.80 0.293 0.59 0.70
4.85 0.295 0.59 0.71
4.90 0.297 0.59 0.71
4.95 0.299 0.60 0.72
5.00 0.301 0.60 0.72