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HOMEPAGE CORONAVI RU S
CORONAVIRUS
CoronavirusComplications:
HowdoesCOVID19affectyour
BODY?
WhileCovid19pandemicsweepsacrosstheglobe,itisimportanttounderstandthe
transmissionandtheeffectoftheviruswhichhasmadeitapandemic.Covid19belongs
tothecoronavirusfamily,whichalsoincludestheSARSvirus(SevereAcuteRespiratory
Syndrome)andMERS(MiddleEastRespiratorySymptoms)virus.Thefamilyof
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Coronavirusincludesvirusstrainsthatcausethecommoncoldandflu.
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It has been found that Covid 19 is a close relative of SARS SARS is a novel type of virus
IthasbeenfoundthatCovid19isacloserelativeofSARS.SARSisanoveltypeofvirus
thatwasreportedin2007,andlikemostSARSviruses,Covid19affectstherespiratory
tractinhumans.Theinfectionstartsoffwithmildflu-likesymptomsornosymptoms,and
furtherprogresstoseveresymptoms.
Covid19primarilyinfectsthelungsintheaffectedindividualsandinseverecasescauses’
deathduetoARDSandpneumonia.Itisimportanttorememberthatitdoesnotleadto
ARDSandpneumoniainallthecases,whichisanoccurrenceinmostseverecases.
Inthemajorityofthecasesi.e.80%willexhibitmildsymptoms,14%willhavepneumonia,
5%willsufferfromsepticshockandorganfailure(mostlyrespiratoryfailure)andin2%
casesitwillbefatal.
SomeoftheprimarysymptomstolookforinaCovid19infectedpersonarefever,
dizziness,breathlessness,headache,drycough(eventuallyresultinphlegm)andinafew
caseslossinsmellandtaste.Afewcaseshavealsoreporteddiarrhoeaandfatigue.
SowhileapersoninfectedwithCovid19canbecured,itisimportanttounderstandthat
thefactorsthatleadtofatality,includeunderlyingillnesses(hypertension,diabetes,
cardiacproblems,respiratoryissues)andindividualswhoareonimmune-suppressing
medications.Inolderindividuals,theriskishigher,astheimmunitydecreaseswithage
andtheyhaveahigherdispositionforotherillnesses.
AnotherimportantaspectinunderstandingCovid19isitseffectonthebodysystem,
especiallythelungs.
AcuteRespiratoryDistressSyndrome(ARDS)
ThereisadirectcorrelationbetweenCovid19andARDS,severecasesofCovid19
infectionleadstoARDSandpneumonia,whichcanprovetobefatalfortheinfected
individual.AcuteRespiratoryDistressSyndromecausesdrycough,heavybreathing,
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breathingdifficultiesandincreasedheartrate.Inmosthealthyindividuals,whodonothave
underlyingissuesCovid19exhibitsmildsymptoms,whichcanbetreatedwithmedications
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and eventually the patients recover In severe cases where the infected person has an
andeventuallythepatientsrecover.Inseverecases,wheretheinfectedpersonhasan
impairedimmunityduetounderlyinghealthconditions,aninfectionduetoCovid19can
progresstosevereARDS.OncethepatientprogressestoARDS,iteventuallyleadsto
pneumonia.
BeforeunderstandingtheseverityofCovid19infection,itisimportanttounderstandthe
differentstages/categoriesofCovid19infection:
Firstcategory:Theseindividualsareinfectedbythevirus,butactascarriersbutmaynot
exhibitthesymptoms.Theseindividualsareatahigherriskofspreadingthevirusasthey
mightbeoblivioustoitspresence.
Secondcategory:Individualswithmildfever,cough,headacheorpossibleconjunctivitis.
Thisisduetoaninfectionintheupperrespiratorytract.
Thirdcategory:Similartothethirdcategory,thesymptomsherearemorepronounced
andmightrequirehospitalization.Immediatetreatmentcanhelpalleviatethesymptoms
andpreventafatality.
Fourthcategory:SeverecasesofCovid19,mightleadtoARDSandpneumonia.Atthis
stage,itisfatal.
EffectofARDSonlungs
Covid19directlyimpactsthelungsanddamagesthealveoli(tinyairsacs).Thefunctionof
thealveolusistotransferoxygentothebloodvessels.Thesebloodvesselsorcapillaries
carrytheoxygentotheRBCs(Redbloodcells).ItistheRBCsthatfinallydeliverthe
oxygentoalltheinternalorgansinthebody.
Thevirusworksbydamagingthewallandtheliningofthealveolusandcapillaries.The
debrisfromthedamage,whichisplasmaproteinaccumulatesonthealveoluswalland ▾
thickensthelining.Asthewalls’thicken,thetransferofoxygentotheredbloodcellsis
impaired.Thethickerthewallgets,themoredifficultitgetstotransferoxygentothered
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blood cells which causes difficulty in breathing as the body is running short of oxygen
bloodcells,whichcausesdifficultyinbreathingasthebodyisrunningshortofoxygen.
Andthelackofoxygentotheinternalorgansresultsinadeficitinthebodyandimpairs
thefunctioningoftheorgans.Atthisjuncture,thebodyfightstoincreaseoxygenintake.
Andthefirstresponseofthebodyistodestroythevirusandpreventitsreplication,butif
theindividualhasweakerimmunitythenthebodyisunabletostopthevirus,andthis
aggravatesthecrisis
Pneumonia
Astheairsacsaredamaged,thereisaninfluxofliquidwhichismostlyinflamedcellsand
proteinandthisfluidbuild-upleadstopneumonia.Thisfurtherimpairstheoxygenintake
bythelungsandhinderstheoxygenexchange.DuetothenoveltyoftheCovid19strain,
thereisnoimmediatetreatmenttodirectlycurepneumoniainCovid19patientsandare
mostlygivensupportivecare.
Howdodoctors’ascertaintheonsetofARDSinCovid19
infectedindividuals?
TherearesomekeyindicatorsthatthedoctorstojudgetheonsetandseverityofARDSin
infectedindividuals:
1.Hypoxia–Lowoxygenlevelsintheblood,duetodamagetothealveolus
2.Breathingdifficultiesandshortnessofbreath
3.Chestx-raysofthelungsexhibitanopaqueandglassylookagainsttheblack
background
4.Worseningsymptomsoverthecourseoftime,fromthedayofdetectionofthevirus
WhileavaccineforCovid19isstillunderworkandmighttakeawhilebeforeitistested
andcertifiedforusage,ourbestbetrightnowistostaysafe,stayindoorsandavoid ▾
crowds.Afewsimpleprecautionslikemaintaininghygieneandsanitizingyour
environmentwillgoalongwayincounteringthespreadofCovid19infection.
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