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Republic of the Philippines

Department of Education
Region II – Cagayan Valley
SCHOOLS DIVISION OF TUGUEGARAO CITY
CAGAYAN NATIONAL HIGH SCHOOL – SENIOR HIGH

The Effect of Aloe Vera (Aloe barbadensis miller) Ointment on the metabolism
rate in healing wounds

1” X 1” 1” X 1” 1” X 1”

Cristine Joy Publico Ashleigh Meave Beltran Reghil Guiyab


G12 STEM Topaz Learner G12 STEM Topaz Learner G12 STEM Topaz Learner
Research Proponent Research Proponent Research Proponent

MARK KENETH C. SUMBILLO


Special Science Teacher I
Research Adviser

A Quantitative Research Submitted to


Science, Technology, Engineering and Mathematics (STEM) Strand
in Partial Fulfilment of the Requirements for Practical Research 2

January 2022

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Telephone Nos.: (078) 304-1923
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Republic of the Philippines
Department of Education
Region II – Cagayan Valley
SCHOOLS DIVISION OF TUGUEGARAO CITY
CAGAYAN NATIONAL HIGH SCHOOL – SENIOR HIGH

TABLE OF CONTENTS

Title Page 1
Table of Contents 2
Abstract 3
Acknowledgement 4
I. THE PROBLEM AND ITS BACKGROUND 5
A. Overview or Background of the Study 6
B. Conceptual Framework 7
C. Research Questions 8
D. Scope and Delimitations 9
E. Significance of the Study 10
F. Definition of Terms 11
II. REVIEW OF RELATED LITERATURE AND RELATED STUDIES 12
III. RESEARCH METHODOLOGY 13
A. Research Design 14
B. Sampling Procedures and Samples 15
C. Data Gathering Methods 16
D. Data Analysis 17
IV. PRESENTATION, ANALYSIS, AND INTERPRETATION OF DATA 18
V. SUMMARY, CONCLUSIONS, AND RECOMMENDATIONS 19
VI. REFERENCES 20
Appendices 21

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Republic of the Philippines
Department of Education
Region II – Cagayan Valley
SCHOOLS DIVISION OF TUGUEGARAO CITY
CAGAYAN NATIONAL HIGH SCHOOL – SENIOR HIGH

TITLE OF QUANTITATIVE RESEARCH

Cristine Joy Publico Ashleigh Meave Beltran Reghil Guiyab


G12 STEM Topaz Learner G12 STEM Topaz Learner G12 STEM Topaz Learner
Research Proponent Research Proponent Research Proponent

MARK KENETH C. SUMBILLO


Special Science Teacher I
Research Adviser

ABSTRACT

Write Abstract here

Keywords: Write keywords here

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Telephone Nos.: (078) 304-1923
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Republic of the Philippines
Department of Education
Region II – Cagayan Valley
SCHOOLS DIVISION OF TUGUEGARAO CITY
CAGAYAN NATIONAL HIGH SCHOOL – SENIOR HIGH

I. THE PROBLEM AND ITS BACKGROUND


A. Overview or Background of the Study
Aloe vera is a medicinal plant that has been utilized in numerous countries
since 1500 BC, including Greece, China, and Mexico. It's also been used as a
traditional treatment for a variety of ailments and skin blemishes for millennia. Aloe
vera is a plant that is native to Madagascar, Saudi Arabia, and Iran. It is an
herbaceous and perennial plant with thick, fleshy, and long leaves that belongs to
the Liliaceae family. It is similar to Cactus and is an herbaceous and perennial plant
with thick, fleshy, and long leaves. Aloe vera was utilized by Egyptian rulers Nefertiti
and Cleopatra as part of their daily beautification routine. Aloe vera has been found
to contain 75 different chemicals, including 20 minerals, 20 amino acids, vitamins,
and water. Aloe vera has been demonstrated to suppress thromboxane (a wound
healing inhibitor), promote wound healing, and reduce inflammation in both in vitro
and in real creature tests. Magnesium lactate, which is present in the gel, inhibits the
generation of histamine, which causes skin irritation and itching. It also improves
immunological function and cytokine production.

Aloe Vera has been prized for its medicinal and cosmetic benefits for hundreds of
years. So much so that Cleopatra, the Egyptian queen known for her beauty, is said
to have relied on this plant for her soft, shining complexion, and Alexander the Great
ordered that it be carried into battle to treat the injured. Aloe Vera is now commonly
utilized in skin care and cosmetic goods, as well as a home treatment in the forms of
gel, juice, and oil. The Aloe Vera moisturizer, which is either distilled or pressed from
the plant, is the most potent. So, what better antidote than Aloe Vera if you want
beautiful skin free of acne and other skin disorders.

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Wound healing is a complex biological process, and the primary goal of medical
therapies is to promote tissue recovery. Burns, vascular disorders, surgery, and
trauma are just some of the causes of skin lesions. Wound healing is a three-phase
process that occurs in a dynamic manner. Inflammation, congestion, and leukocyte
infiltration are all part of the initial phase. The clearance of dead tissue is the second
phase, while epithelial regeneration and fibrous tissue creation are the third phases
of proliferation. Aloe vera has been studied and found to be useful in the prevention
and healing of skin lesions in several studies.

Aloe vera works to reduce inflammation by suppressing IL-6 and IL-8, reducing
leukocyte adhesion, increasing IL-10 levels, and decreasing TNF alpha levels. The
component glucomannan, which is high in polysaccharides like mannose, is
responsible for its regenerating capabilities. The component glucomannan, which is
high in polysaccharides like mannose, is fundamental for its regenerating
capabilities. Glucomannan stimulates the activity and proliferation of fibroblast
growth factor receptors, which leads to an increase in collagen synthesis.
Aloe vera gel can not only increase the amount of collagen in wounds, but it can also
change the collagen's composition, boost collagen cross-linking, and therefore
promote wound healing. Because the gel is 99 percent water, scientific tests have
shown that it can promote skin flexibility and minimize fragility. Aloe vera also
contains mucopolysaccharides, amino acids, and zinc, which can cause skin
irritation.
Aloe vera also contains mucopolysaccharides, amino acids, and zinc, which can help
with skin integrity, moisture retention, erythema reduction, and the prevention of skin
ulcers. Psoriasis, mouth sores, ulcers, diabetes, herpes, bedsores, and burn wounds
have all been shown to benefit from Aloe vera. Aloe vera is known for its anti-tumour,

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anti-inflammatory, skin protection, anti-diabetic, anti-bacterial, anti-viral, antiseptic,


and wound healing properties.
The current study aims to examine research studies on the effect of Aloe vera on the
prevention and healing of skin wounds, given the availability of multiple clinical trials
on the topic, as well as its popularity among consumers and extensive use in the
beauty sector.

B. Conceptual Framework

INPUT PROCESS OUTPUT

-Aloe Vera -Aloe Vera is -The


plant/leaf extractedeffectiveness
from of
containing 75 the plant and is
Aloe Vera in the
different either distilled or
prevention and
chemicals, pressed.treatment of
including 20 -Analyze skin
the sores, as
minerals, 20 informationwell as its
amino acids, widespread use
gathered
vitamins, and in the cosmetic
water. industry.

Figure 1. Input – Process – Output Diagram on the Effectiveness of Aloe Vera Ointment on
the metabolism rate in healing wounds
The guiding principle of the study aims to demonstrate, as shown in Figure 1
above that Aloe Vera has been studied and found to be useful in the prevention and
healing of skin lesions in several studies and has been prized for its medicinal and
cosmetic benefits for hundred years.

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Telephone Nos.: (078) 304-1923
Email Address: cnhs.tuguegarao@deped.gov.ph
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Republic of the Philippines
Department of Education
Region II – Cagayan Valley
SCHOOLS DIVISION OF TUGUEGARAO CITY
CAGAYAN NATIONAL HIGH SCHOOL – SENIOR HIGH

C. Research Questions
E. Scope and Delimitations
F. Significance of the Study
G. Definition of Terms

II. REVIEW OF RELATED LITERATURE AND RELATED STUDIES

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Telephone Nos.: (078) 304-1923
Email Address: cnhs.tuguegarao@deped.gov.ph
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Republic of the Philippines
Department of Education
Region II – Cagayan Valley
SCHOOLS DIVISION OF TUGUEGARAO CITY
CAGAYAN NATIONAL HIGH SCHOOL – SENIOR HIGH

III. RESEARCH METHODOLOGY

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Republic of the Philippines
Department of Education
Region II – Cagayan Valley
SCHOOLS DIVISION OF TUGUEGARAO CITY
CAGAYAN NATIONAL HIGH SCHOOL – SENIOR HIGH

A. Research Design
B. Sampling Procedures and Samples
C. Data Gathering Methods
D. Data Analysis

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Telephone Nos.: (078) 304-1923
Email Address: cnhs.tuguegarao@deped.gov.ph
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Department of Education
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SCHOOLS DIVISION OF TUGUEGARAO CITY
CAGAYAN NATIONAL HIGH SCHOOL – SENIOR HIGH

IV. PRESENTATION, ANALYSIS, AND INTERPRETATION OF DATA

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Telephone Nos.: (078) 304-1923
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Department of Education
Region II – Cagayan Valley
SCHOOLS DIVISION OF TUGUEGARAO CITY
CAGAYAN NATIONAL HIGH SCHOOL – SENIOR HIGH

V. SUMMARY, CONCLUSIONS, AND RECOMMENDATIONS

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Telephone Nos.: (078) 304-1923
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Republic of the Philippines
Department of Education
Region II – Cagayan Valley
SCHOOLS DIVISION OF TUGUEGARAO CITY
CAGAYAN NATIONAL HIGH SCHOOL – SENIOR HIGH

VI. REFERENCES

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