PreSep Oximetry Catheter

The security of
an early warning
The PreSep oximetry catheter. The proactive decision.

In the critically ill, traditional vital signs may be late indicators of compromised or inadequate oxygen
delivery to the tissues. By providing a real-time, global measure of oxygen balance, the PreSep oximetry
1-5
catheter detects critical changes earlier – enabling you to detect and prevent tissue hypoxia sooner.

Continuous ScvO2 monitoring is key to assessing the adequacy of the balance of oxygen delivery
and consumption. The goal of continuous ScvO2 monitoring with the PreSep oximetry catheter is to
bring into balance the relationship between oxygen delivery and consumption to improve the care
6
of high-acuity patients.

PreSep Oligon Oximetry Catheter*

with integrated antimicrobial protection

ScvO2

PreSep
Oximetry Catheter

Convenient, accurate and easy to use

• The first proven central venous catheter with continuous ScvO2 monitoring
7
• Accurate versus CO-oximeter
• Simple to use – same insertion techniques as that of a central line
The proven advantage of continuous ScvO2 monitoring.

Continuous ScvO2 monitoring is proven to reduce

mortality, comorbidities, hospital costs and length of stay Advantages of
when compared to intermittent sampling. The prognostic Continuous ScvO2
2 8
value of ScvO2 has been demonstrated in high-risk surgery, Outcomes using continuous central
4 2,9 6,7
trauma, sepsis, cardiac failure in CHF and recovery venous oxygen saturation versus
10,11
in cardiac arrest. standard central venous catheters
in sepsis management.
• Reduction in total hospital charges
• Continuous ScvO2 is a more sensitive indicator of tissue of $82,262 per case
perfusion compared to intermittent sampling and traditional • D ecrease in hospital length of stay
1-5
vital signs alone by 7.48 days
Source: Comparison of continuous central
• Continuous ScvO2 monitoring reveals the true adequacy venous oxygen saturation and standard central
venous catheters in septic patients at a large,
of tissue oxygenation, enabling early detection and assessment non-academic tertiary medical center.
1,2 Crit Care Med. 2009;37(12) (suppl).14
of clinical response to intervention
Decrease in patient mortality rate
1-5
• Continuous ScvO2 highly correlates and trends with SvO2
while providing the same utility in monitoring, which is essential
12
in defining the adequacy of cardiac output

CARDIAC OUTPUT HEMOGLOBIN

38.7%
Hypovolemia Bleeding • Internal Bleeding
Left Ventricular Failure Coagulopathies 26.5%
CHF • Pacing Transfusion
High CO - Early Sepsis Continuous Intermittent
Low CO - Late Sepsis ScvO2 monitoring monitoring

Increase in patients reaching six-hour goal

ScvO2
75.7%
60.3%
OXYGENATION O2 CONSUMPTION
Ventilation Burns • Fever
Oxygenation Shivering • Seizures
Failure to Tolerate Extubation Work of Breathing • Sepsis
Continuous Intermittent
ScvO2 monitoring monitoring
Figure 1
Source: Effect of intermittent vs. continuous
ScvO2 monitoring on sepsis bundle compliance
The PreSep oximetry catheter, from Edwards Lifesciences. and mortality. Am Coll Chest Physicians. 2009.15
The security of an early warning. For clarity, in every moment.

Clinical applications of ScvO2

ScvO2 and SvO2 are affected by the same four factors and trend together more than 90% of the time.
Thus, most of the research and clinical applications documented for SvO2 should apply to ScvO2.
Figure 1 provides examples of clinical situations where ScvO2 monitoring may be helpful in identifying
13
imbalances between DO2 and VO2.
FloTrac Sensor EV1000 Clinical Platform PreSep Oximetry Catheter
The FloTrac sensor is the easy and The EV1000 clinical platform The PreSep oximetry catheter
reliable solution for optimizing fluid presents the physiologic may be used with the EV1000
management. Less invasive and status of the patient in an clinical platform or the Vigileo
easily attaches via any standard entirely new, intuitive way monitor to continuously
arterial catheter, the FloTrac sensor and also works with the measure and display key
gives you access to continuous PreSep catheter and FloTrac flow parameters, including
cardiac output, stroke volume, sensor for a single, integrated continuous ScvO2.
stroke volume variation and systemic platform. The PreSep catheter
vascular resistance – under may also be used with the
numerous patient conditions. Vigileo monitor.
When combined with the continuous
ScvO2 monitoring of the PreSep
oximetry catheter, you’ll also find
a clear path to improving sepsis
patient outcomes.

Helping to advance the care of the critically ill for 40 years, Edwards Lifesciences seeks to provide the valuable
information you need, the moment you need it. Through continuing collaboration with you, ongoing education
and our never-ending quest for advancement, our goal is to deliver clarity in every moment.

Visit www.Edwards.com/PreSep to learn more

Reference:
1. Reinhart K, et al. Continuous central venous and pulmonary artery oxygen saturation monitoring in the critically ill. Intensive Care Med. 2004;30(8):1572-8.
2. Rivers EP, et al. Central venous oxygen saturation monitoring in the critically ill patient. Curr Opin Crit Care. 2001;7(3):204-11.
3. Ingelmo P, et al. Importance of monitoring in high risk surgical patients. Minerva Anestesiol. 2002;68(4):226-30.
4. Scalea TM, et al. Central venous oxygen saturation: a useful clinical tool in trauma patients. J Trauma. 1990;30(12):1539-43.
5. Ander DS, et al. Undetected cardiogenic shock in patients with congestive heart failure presenting to the emergency department. Am J Cardiol. 1998;82(7):888-91.
6. Loren D. Continuous venous oximetry in surgical patients. Ann Surg. 1986;203/3:329-333.
7. Edwards, Vigileo Operators Manual: A-4.
8. Pearse R, et al. Changes in central venous saturation after major surgery, and association with outcome. Crit Care. 2005;9(6):R694-9.
9. Rady MY, et al. Resuscitation of the critically ill in the ED: responses of blood pressure, heart rate, shock index, central venous oxygen saturation, and lactate. Am J Emerg
Med. 1996;14(2):218-25.
10. Nakazawa K, et al. Usefulness of central venous oxygen saturation monitoring during cardiopulmonary resuscitation. A comparative case study with end-tidal carbon dioxide
monitoring. Intensive Care Med. 1994;20(6):450-1.
11. Rivers EP, et al. The clinical implications of continuous central venous oxygen saturation during human CPR. Ann Emerg Med. 1992;21(9):1094-101.
12. Pinsky MR, et al. Let us use the pulmonary artery catheter correctly and only when we need it. Crit Care Med. 2005;33(5):1119-22.
13. Zaja J. Venous oximetry. Singa Vitae. 2007;2(1):6-10.
14. Maxwell D, et al. Comparison of continuous central venous oxygen saturation and standard central venous catheters in septic patients at a large, non-academic tertiary
medical center. Crit Care Med. 2009;37(12) (suppl).
15. Ising P, et al. Effect of intermittent vs. continuous ScvO2 monitoring on sepsis bundle compliance and mortality. Am Coll Chest Physicians. 2009.

For professional use. CAUTION: Federal (United States) law restricts this device to sale by or on the order of a physician.
See instructions for use for full prescribing information, including indications, contraindications, warnings, precautions
and adverse events.
Edwards, Edwards Lifesciences, the stylized E logo, EV1000, FloTrac, PreSep, and Vigileo are trademarks of Edwards Lifesciences Corporation. All other
trademarks are the property of their respective owners.

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