QP Code: 321006 Reg. No……………………….

Third Semester B.Pharm Degree Examinations January 2019

Pharmaceutical Organic Chemistry - II

(2017 Scheme)
Time: 3 Hours Max. Marks: 75
 Answer all questions
 Draw Chemical Structures wherever necessary
Essays (2x10=20)

1. What is resonance. Write the resonance stabilization of benzene. Explain with

mechanism of reaction sulphonation and halogenation reaction of benzene.
2. Write the Haworth synthesis of Phenanthrene and write any two reactions,
medicinally important derivatives of it along with their uses.

Short Notes (7x5=35)

3. What are diazonium salts. Write any two coupling and displacement reactions.
4. Arrange the following compounds in the increasing order of acidity with
justification: phenol, picric acid, o-cresol, m-nitrophenol.
5. Explain Sachse Mohr’s theory.
6. What is saponification value and iodine value. Give their significance.
7. Write the structures of the following compounds:
BHC, Triphenylmethane, Anthracene, Saccharin, DDT.
8. Write any two methods synthesis and reaction of cyclobutane.
9. Explain the theory of reactivity of methyl group attached to the phenyl ring

Answer Briefly (10x2=20)

10. What is rancidity

11. Write the examples of saturated and unsaturated fatty acid.
12. Bond angles of cyclopropane
13. Write any two reactions of cyclopropane
14. Reagents used in Friedal-Crafts acylation of benzene.
15. Compare the basicity of aniline and triethylamine.
16. Why aniline undergo bromination more readily than toluene.
17. Write any one qualitative test for phenols.
18. What is hydrogenation of oils
19. Name the medicinally important derivatives and uses of naphthalene

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QP Code: 321006 Reg. No……………………….

Third Semester B.Pharm Degree Supplementary Examinations

June 2019
Pharmaceutical Organic Chemistry - II

(2017 Scheme)
Time: 3 Hours Max. Marks: 75
 Answer all questions
 Draw Chemical Structures wherever necessary
Essays (2x10=20)

1. What are oils. Give examples for saturated and unsaturated fatty acids. Define
acid value, saponification value, iodine value along with their significance.
2. What are fused poly-nuclear hydrocarbons. Write the Haworth synthesis of
naphthalene and any two chemical reactions of it. Name the medicinally
important derivatives of naphthalene along with uses.

Short Notes (7x5=35)

3. Explain Friedal-Crafts alkylation reaction of benzene with mechanism and write

its limitations.
4. Arrange the following in their increasing order of basicity with justification:
Aniline, Ammonia, Triethylamine, N-methylaniline.
5. What is Baeyer’s strain theory. Write its limitations.
6. What are diazonium salts. Name the different types of reactions with any two
examples of it.
7. Write the structure of the following compounds: DDT, Diphenyl methane,
Chloramine, Anthracene, Saccharin.
8. Explain Huckel’s rule with examples.
9. Give the characteristic identification tests for phenols

Answer Briefly (10x2=20)

10. What is the nitrating mixture used for its reaction in benzene.
11. Write any two reactions of cycloalkanes.
12. Why phenols undergo bromination reaction more readily than methoxybenzene.
13. Name the functional groups that deactivate aromatic ring.
14. Name the water soluble phenol and write its structure.
15. Compare the acidity of phenol with o-cresol.
16. What is hydrogenation of oils
17. Resonance structures of benzene and resonance stabilization.
18. Name the medicinally important derivatives along with uses of phenanthrene.
19. What is the bond angle in cyclohexane

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QP Code: 321006 Reg. No……………………….

Third Semester B.Pharm Degree Supplementary Examinations

December 2020

Pharmaceutical Organic Chemistry - II

(2017 Scheme)
Time: 3 Hours Max. Marks: 75
 Answer all questions to the point neatly and legibly • Do not leave any blank pages between
answers • Indicate the question number correctly for the answer in the margin space
 Answer all parts of a single question together • Leave sufficient space between answers
 Draw table/diagrams/flow charts wherever necessary
Essays (2x10=20)

1. Outline any two methods of synthesis of anthracene and discuss four important
reactions of anthracene
2. Explain the effect of substituents on reactivity of mono substituted benzene
towards electrophilic aromatic substitution

Short Notes (7x5=35)

3. Discuss Baeyer’s strain theory.

4. Define iodine value and explain the method of determination and significance of
iodine value.
5. Discuss the effect of substituents on basicity of amines.
6. Important chemical reactions of cyclopropane
7. Discuss the acidity of phenols
8. Explain nitration reactions of benzene with mechanism
9. Two important reactions of phenanthrene and triphenyl methane

Answer Briefly (10x2=20)

10. Structure and uses of chloramine.

11. Reichert Meissel value
12. Limitations of friedelcrafts alkylation reaction
13. Define drying, semidrying and nondrying oils with examples
14. Significance of carbylamine test
15. Coulson and Moffitt’s modification
16. Two uses of diphenyl methane
17. Hydrogenation reactions of oils
18. Define acetyl value and give its significance
19. Two important synthetic uses of aryl diazonium salts

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QP Code: 321006 Reg. No……………………….

Third Semester B.Pharm Degree Regular/Supplementary

Examinations January 2020

Pharmaceutical Organic Chemistry - II

(2017 Scheme)
Time: 3 Hours Max. Marks: 75
 Answer all questions
 Draw Chemical Structures wherever necessary
Essays (2x10=20)

1. Explain Huckels rule. Write the theory of reactivity of activating and deactivating
group present on the phenyl ring.
2. What are fused polynuclear hydrocarbons. Write the Haworth synthesis of
naphthalene and any two chemical reactions of it. Name the medicinally
important derivatives of naphthalene along with uses.

Short Notes (7x5=35)

3. Define iodine value. What are drying oils and non-drying oils. Give examples.
4. Arrange the following in their increasing order of basicity with justification:
Dimethylamine, Ammonia, Triethylamine, N-methylaniline.
5. What is Baeyer strain theory. Write its limitations.
6. Explain the Friedal-Crafts acylation of benzene with mechanism of reaction.
7. Give the characteristic identification tests for phenols.
8. What are isolated polynuclear hydrocarbons. Give any one synthesis and
reaction of diphenylmethane.
9. What are oils. Give examples of saturated and unsaturated fatty acid

Answer Briefly (10x2=20)

10. What is ester value. Mention its significance.

11. What is rancidity of oils
12. Name the medicinally important derivatives of phenanthrene and their uses.
13. Any one method of synthesis of cyclopropane.
14. The structure of DDT and chloramine
15. Structure of water soluble phenols.
16. What is hydrogenation of oils
17. The bond angles of cyclohexane.
18. The reactions of cyclobutane.
19. Compare the acidity of m-cresol and m-nitrophenol

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