Sialography

Sialography (also termed radiosialography) is the radiographic examination of the salivary

glands. It usually involves the injection of a small amount of contrast medium into the salivary
duct of a single gland, followed by routine X-ray projections.[1]

Sialography

Sialogram in a patient suspected of Sjögren's syndrome

MeSH D012796 (https://www.nlm.nih.gov/cgi/mesh/201

6/MB_cgi?field=uid&term=D012796)

MedlinePlus 003812 (https://medlineplus.gov/ency/article/003

812.htm)

[edit on Wikidata]

The resulting image is called a sialogram.

Sialography has largely been replaced by sialoendoscopy[2] and cross-sectional imaging, such as
CT, MRI and ultrasonography.[3]

Indications

Indications include:

In the evaluation of the functional integrity of the salivary glands

In case of obstructions

To evaluate the ductal pattern

In case of facial swellings, to rule out salivary gland pathology

In case of intra-glandular neoplasms.

Contraindications include:

Persons who are allergic to iodine and/or contrast medium.

Cases where there is acute infection,

patients with thyroid function tests

When calculi are located in anterior part of the salivary gland duct

Procedure

Contrast agents are classified into two groups: fat-soluble contrast agents and water-soluble
contrast agents. Water-soluble contrast agents can fill the finer elements of the ductal system.
Fat-soluble contrast agents are viscous and can cause allergic reactions. These can also cause
discomfort to the patients. Fat-soluble contrast agents do not fill finer elements of the duct.

A baseline radiograph (scout film) of the required salivary gland would be taken, the duct is
dilated using graded lacrimal probes, a cannula then is inserted in this salivary gland duct's
opening in the mouth, then a radio-opaque fluid (contrast medium) is injected in the duct through
a small tube.

A series of radiographs would then be taken to determine the flow of the fluid, identify any
obstructions and its location, the rate of fluid excretion from the gland.
Usually the radiographs taken are lateral oblique views of the face[4] as orthopantomograms are
not useful for the purpose of locating the area due to superimpositions and the way they are
taken to put the teeth in the main field.

Interpretation

This study is interpreted by evaluating the morphology of the salivary ducts for obstructions and
chronic inflammation. Sialodochitis is a term describing dilation of the ducts caused by repeated
inflammatory or infective processes. There is also irregular salivary duct stricture (narrowing) of
the duct, which creates an appearance known as "sausage link" pattern on a sialogram.
Suggestions of abscesses and autoimmune diseases such as Sjögren syndrome can also be
elicited. Sialadenitis is inflammation of the salivary glands, which may cause acinar atrophy and
create an appearance known as "pruning of the tree" on a sialogram, where there are less
branches visible from the duct system. A space occupying lesion that occurs within or adjacent
to a salivary gland can displace the normal anatomy of the gland. This may create an
appearance known as "ball in hand" on an sialogram, where the ducts are curved around the
mass of the lesion.[5]

Adverse effects

Like any medical imaging utilizing ionizing radiation, there will be a degree of direct ionizing
damage and indirect damage from free radicals created during the ionization of water molecules
within cells. The risk of causing the development of a malignant tumor is incredibly small, and is
weighed against the benefits of the investigation on a case by case basis.

Possible complications include:

Pain on injection,

Post procedural infection,

Ductal rupture,

Extravasation of contrast media,

Allergic reaction to iodinated contrast media (which may present with urticaria, dyspnoea, and
hypotension).

References
 1. "Sialogram on MedlinePlus" (https://www.nlm.nih.gov/medlineplus/ency/article/003812.htm) . NIH /
NLM. Retrieved 18 April 2013.

2. Pniak, Tomáš; Štrympl, Pavel; Staníková, Lucia; Zeleník, Karol; Matoušek, Petr; Komínek, Pavel (1 January
2016). "Sialoendoscopy, sialography, and ultrasound: a comparison of diagnostic methods" (https://doi.
org/10.1515%2Fmed-2016-0081) . Open Medicine. 11 (1): 461–464. doi:10.1515/med-2016-0081 (http
s://doi.org/10.1515%2Fmed-2016-0081) .

3. Rzymska-Grala, Iwona; Stopa, Zygmunt; Grala, Bartłomiej; Gołębiowski, Marek; Wanyura, Hubert;
Zuchowska, Anna; Sawicka, Monika; Zmorzyński, Michał (July 2010). "Salivary gland calculi -
contemporary methods of imaging" (https://www.ncbi.nlm.nih.gov/pubmed/22802788) . Polish
Journal of Radiology. 75 (3): 25–37. ISSN 1733-134X (https://www.worldcat.org/issn/1733-134X) .

4. "Sialography" (https://archive.is/20120207190910/http://www.medcyclopaedia.com/library/topics/volu
me_i/s/sialography.aspx) . Medcyclopaedia. GE. Archived from the original (http://www.medcyclopaedi
a.com/library/topics/volume_i/s/sialography.aspx) on 2012-02-07.

5. Hupp JR, Ellis E, Tucker MR (2008). Contemporary oral and maxillofacial surgery (5th ed.). St. Louis, Mo.:
Mosby Elsevier. pp. 402–405. ISBN 9780323049030.

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