Professional Documents
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KEY POINTS
• The objectives of cleft lip repair are to reestablish an addressing the medial shortening and lateral displacement
anatomic and functional balance between the soft tissues while restoring normal anatomy, lip length, and symmetry.
and the skeleton. This is achieved by reestablishing normal • Repair of a bilateral cleft lip is characterized by a huge
insertions of all the nasolabial muscles and correct diversity of treatment protocols that are often associated
anatomical position of the soft tissues recreating the with more long-term issues than unilateral clefts.
appearance of the non cleft lip. • Nasoalveolar molding (NAM) is promising but
• We advocate an advancement/rotation repair of the objective analysis of long-term outcome has not yet been
unilateral cleft lip incorporating an inferior triangular flap reported.
948
CHAPTER 67 Techniques for Cleft Lip Repair 949
A B
FIG 67-1 Development of the facial processes. A, Representation of a 30- to 32-day-old human
embryo showing the development of the facial processes. FNP, Frontal nasal process; LNP,
lateral nasal process; MAN, mandibular process; MAX, maxillary process; MNP, medial nasal
process. B, Representation of an 8 12 -week-old embryo showing the fate of the facial process.
Bilateral
Right + Left
Nose Median
Alveolus
Incisive fossa
A B
Hard palate
Secondary palate
Soft palate
Line of cleft
3. Hard palate
4. Soft palate Examples of the LAHSAL Cleft Classification
5. Left alveolus Some examples of the LAHSAL cleft classification are as follows:
6. Left lip • Bilateral complete cleft of lip and palate: A complete bilat-
The code is then written as if looking at the patient. The first eral cleft lip and palate is represented by all six capital
character is for the patient’s right lip and the last for the left lip. letters—LAHSAL.
Complete clefts are recorded in upper case and partial clefts in • Right incomplete cleft lip: A right incomplete cleft lip is
lowercase, and microform clefts are denoted by an asterisk. No represented by the lowercase letter “l” only. Because it is on
cleft is represented with a dot. This classification system is used the right, the “l” is written at the beginning—“l….”
in the United Kingdom because it has the advantage of being • Left complete cleft lip and palate: A left complete cleft lip is
easy to record in medical records and electronically. represented by the capital letters HSAL. Because it is on the
left, the HSAL is written at the end—“…HSAL.”
• Left incomplete cleft lip and alveolus: A left incomplete cleft
lip and alveolus is represented by the lowercase letters “a” and
“l” and they are written at the end—“…al.”
• Incomplete hard palate and complete soft palate cleft: An
incomplete cleft of the hard palate is represented by the
lowercase letter “h,” and the complete cleft of the soft palate
is represented with the capital letter “S”—“…hS….”
Muscle Anatomy
The upper lip is formed by a series of three interconnected
muscle rings extending from the infraorbital rim and nose
down to the chin (Figure 67-6, A). These nasolabial
FIG 67-4 LAHSAL cleft classification. muscle rings form part of the fascial envelope in continuity
Lateral Shortening of
displacement of skin of medial
skin on the side with
lateral side vertical soft
tissue
deficiency
Pale raised
ridge
Sterile
mucosa
Sterile
mucosa
White roll
A B
FIG 67-6 A, Nasolabial muscle ring in the non-cleft lip. B, Nasolabial muscle ring in the unilateral
cleft lip.
with the superficial musculo-aponeurotic system (SMAS) (see of the cleft. These muscle fibers are interspersed with connective
Figure 67-6, A). tissue.
In the unilateral cleft lip and palate, the upper and middle Some general observations from the perspective of cleft lip
muscle rings are incomplete (see Figure 67-6, B). All the muscle repair are apparent:
groups on the cleft margins of the cleft, which normally insert • The upper and lower muscle rings converge toward the ANS
onto the anterior nasal spine (ANS), septum, and anterior and nasal septum.
surface of the premaxilla, become bunched up at the border of • The transverse nasalis muscle intermingles with the levator
the cleft. The abnormal muscle function produces characteristic labii superioris and levator labii superioris alaeque nasi to
nasal and mucocutaneous abnormalities, which have to be form a modiolus that fans out to insert into the nasal sill. It
addressed at the time of primary lip repair. The unilateral cleft influences the shape and position of the ala cartilage and the
lip is characterized by discontinuity, disorientation, and mal height of the nasal sill.
insertion of the orbicularis muscle, causing horizontal and ver- • The almost vertical orientation of the external or superficial
tical lip discrepancy. In a complete cleft lip, the deep fibers of part of the orbicularis oris and its connections with the
the orbicularis oris muscle are interrupted by the cleft. In addi- muscles of the upper ring and with the lower ring through
tion, the superficial component of the orbicularis oris turns the modiolus are significant.
upward, along the margins of the cleft, and it ends beneath the
base of the ala or columella. Nasal Anatomy
Incomplete cleft lip behaves in a similar manner, except The obvious deformity of nasal form in unilateral cleft lip and/
when the cleft is less than two-thirds of the height of the lip. In or palate is due to the incorrect insertion of the transverse
this case, the fibers of the muscle run along the margins of the nasalis muscle and displacement of the septum (Figure 67-7).
cleft, then change direction and run horizontally over the top The muscle in the lateral element is deprived of insertion to the
952 CHAPTER 67 Techniques for Cleft Lip Repair
ANS and pulls the lateral lip element and alar base of the nose UNILATERAL INCOMPLETE CLEFT LIP ANATOMY
laterally. The alar cartilage is flattened and deformed but is not
hypoplastic. The lateral crus of the lower lateral cartilage is Microform cleft lip involves partial or total clefting of the upper
pulled laterally and lengthened at the expense of the medial crus lip musculature (Figure 67-8). Incomplete cleft lip involves skin,
thereby flattening the dome. Its inferior border is also rotated muscle, and mucosa, but it may spare the underlying skeletal
inferiorly forming a web inside the nostril. The anterior nasal structures (Figure 67-9). Complete unilateral cleft lip involves
septum and columella are deviated to the medial side. The skin, muscle, mucosa, and underlying skeletal framework.
anterior part of the greater segment of the maxillofacial complex There are subtle textural differences between the nasal skin
is displaced anteriorly due to lack of molding of the nasolabial and lip skin in an incomplete cleft lip. During the repair of a
muscles. cleft lip, they are separated at their junctions to align nasal skin
The anatomical features of the nose in unilateral complete with nasal skin and lip skin with lip skin.
cleft lip are illustrated in Figure 67-7 and are listed in Box 67-1. Muscle dissections in stillborn babies have shown that the
upper lip muscles in incomplete cleft do not cross the cleft gap
unless the skin bridge is greater than one-third of the height of
BOX 67-1 Anatomical Features of the
the lip.18 Even if orbicularis oris muscle is present in the skin
Nose in Unilateral Cleft Lip bridge, the orientation of the fibers is abnormal and the mus-
Abnormal muscle insertions into nasal spine away from cleft culature is not functionally correct. Therefore repair of the
Defect in primary palate anterior to incisive foramen incomplete cleft lip requires a full muscle dissection on the
Rotation of septum, columella, and nasal spine away from cleft medial and lateral segments to allow for a functional muscle
Separation of domes of the alar cartilage at the nasal tip and kinking of
the lateral crus on the cleft side
repair across the cleft.
Dislocation of lower and upper lateral cartilages on the cleft side
Displacement of alar base in all three planes BILATERAL CLEFT LIP ANATOMY
Inferior displacement of the medial crus within the columella
Dislocation of the caudal portion of the septum to the non-cleft side Skin
from the nasal spine The anatomic skin characteristics of bilateral cleft lips are deter-
Displacement and flattening of the nasal bone on the cleft side
mined by the degree of completeness of the cleft and its sym-
Deflection of the nasal tip toward the non-cleft side
Retroposition of the cleft alar cartilage dome metry. The prolabial skin in bilateral cleft lip varies in size, is
Obtuse angle between the medial and lateral crura of the lower lateral often retracted, and lacks muscle fibers (Figure 67-10). In addi-
cartilage on the cleft side tion, the columella is shortened, and the prolabium appears
Absence of the alar-facial groove on the cleft side and attachment of attached to the top of the nose in some cases. The size and posi-
the ala to the face at an obtuse angle tion of the premaxilla varies but it is rotated upward and pro-
Larger nares on the cleft side
truded. In some cases, it can be excluded from the alveolar arch
Shorter columella on the cleft side, positioning the entire columella at
a slant toward the non-cleft side
with a collapse of the lateral elements. The isolated prolabium
is deprived of muscle and normal vermilion and is lined by
Nasal skin
Absence of functional
muscle in skin bridge
Lip skin
Apparent
absence of
columella
Abnormal
Retracted prolabial vermilion
skin lacking continuity of lined by
orbicularis oris muscle fibers sterile
mucosa
Protrusion
and rotation Collapse of
of premaxilla lateral palatal
segments
behind the
premaxilla
sterile mucosa. The prolabium located centrally is devoid of segments, the lip vermillion is turned upward to join the alar
muscle and consists of skin, vermilion, and oral mucosa. base. This is because the levator alaeque nasi, levator labii supe-
There is no definitive line of demarcation between the colu- rioris, transverse nasalis, and intrinsic upper lip muscles orbi-
mella and prolabium. The premaxilla may be situated centrally, cularis marginalis are oriented upward and inserted into the
asymmetrically to the right or left, anteriorly, superiorly, or alar base and maxilla along the pyriform ring (Figures 67-12,
inferiorly, or a combination of thereof (Figure 67-11). 67-13, and 67-14), resulting in an absence of muscle in the
prolabial segment.
Muscle
The nasolabial muscle rings are disrupted in complete bilateral Nose
cleft lips, and their abnormal insertions result in lateral dis- The nasolabial deformity in bilateral cleft lip and palate is
placement of the lateral nasolabial elements. On the lateral largely caused by secondary hypoplasia rather than primary
954 CHAPTER 67 Techniques for Cleft Lip Repair
A B
FIG 67-12 A, Nasolabial muscle ring in the non-cleft lip. B, Nasolabial muscle ring disruption in
a complete bilateral cleft lip.
mesenchymal deficiency.19 The most important feature of the 67-15). The lower lateral cartilages are pulled laterally, resulting
bilateral cleft is the short columella that is produced by an unop- in a flattened appearance of the nose. The septum and premax-
posed muscular pull on elements of the lateral cleft in the early illa are attached to the vomer as a thin stalk. Alar domes and
stages of fetal development. The bilateral nasal cleft is seldom middle crura are splayed, caudally rotated (bucket handle), and
corrected by functional surgery alone, and the appearance of a subluxed from their normal anatomic position overlying upper
repaired bilateral cleft lip is often dominated by the short, teth- lateral cartilages. The nasal tip appears large, flat, and bifid,
ered appearance of the columella, and a broad nasal tip (Figure because both alae are rotated downward and spread apart.
CHAPTER 67 Techniques for Cleft Lip Repair 955
PHILOSOPHY OF CLEFT LIP REPAIR quadrangular flap (Le Mesurier), or a combination of the
advancement rotation and wavy line techniques (Afroze).20-24
The essential objectives of cleft lip repair are the restoration of The skin of the lip on the medial element is short as a con-
normal function and appearance of the lip and nose. This is sequence of the change in normal muscular actions. Careful
achieved by reestablishing normal insertions of all the nasola- reconstruction of the nasolabial muscles allows the overlying
bial muscles and correct anatomical position of the other soft skin to lengthen to the correct lip height.
tissues, including the mucocutaneous elements. Therefore, an • Muscle: The fundamental goal of surgery is to achieve ana-
anatomic and functional balance between the soft tissues and tomic muscular reconstruction, particularly with respect to
the skeleton is reestablished. anchorage of the complex nasolabial muscles of the cleft side
• Skin: The skin is corrected in both vertical and horizontal to the nasal septum and muscles on the non-cleft side (see
orientation. To restore normal height of both sides of the Figure 67-15). It is necessary to reconstruct the nasolabial
cleft relative to the non-cleft side, it is necessary to restore muscles of the cleft such that the skin margins are not under
the normal length of the skin on the cleft side using various
techniques, such as the rotation advancement design (Delaire
and Millard), undulating wavy flaps (Pfeiffer), straight line
design (Rose-Thompson), lower lip Z-plasties/triangular
flaps (Tennison-Randall, Skoog, Trauner, or Malek), the
Short tethered
columella
Caudal rotation of
splayed alar domes
tension at the moment of skin closure (Figure 67-16). If the • Muscle attachments of the medial side: The most nasal
primary nasolabial muscle reconstruction is good, anatomy, and deep bundles of orbicularis muscle insert into the
function, skeletal growth, and total facial esthetics can be mucoperichondrium and anterior nasal septum. There-
excellent. fore, they pull the caudal part of the septum toward the
• Nose: The nasal septum is deviated in unilateral cleft lip. medial side.
There are two reasons for this: Septal deviation causes the upper lateral cartilage to buckle,
• Position of the ANS: It is positioned toward the non-cleft depressing the radix, and also causes the lower lateral cartilagi-
side and therefore pulls the septum, which is attached to nous framework to shift, thereby collapsing the dome on the
it toward the non-cleft side. lateral side (Figure 67-17).
A B
FIG 67-16 A, Functional muscle reconstruction in unilateral cleft lip. B, Muscle in repaired uni-
lateral cleft lip.
Septoplasty at the time of lip repair produces a straighter continuity with the floor of nose. There is no evidence to
nasal septum positioned in the facial midline and restores the support the hypothesis that vomer flaps restrict maxillary
patency and natural width of the nostril (Figure 67-18). To growth.25
achieve the proper midline position and attitude of the nasal
septum, the surgeon must perform a wide subperichondrial Alveolar Cleft Segments
dissection on both sides of the septum. Once the deviated nasal The distance between the greater and lesser segments is propor-
septum is repositioned, nostril patency is reestablished on the tional to the width of the cleft lip. The segments will be approxi-
cleft side. mated from pressure exerted on them by the repaired cleft lip
The nasal floor is also reconstructed to eliminate the vestibu- molding the anterior element of the greater segment as shown
lar oral nasal communication if the palate is involved. A vomer in the preoperative (Figure 67-19) and postoperative (Figure
flap is used when possible to repair the anterior hard palate in 67-20) molds of cleft lip repairs.
Septoplasty repositions
the nasal septum
Restoration of patency
and natural width of
the nostril
FIG 67-18 Septoplasty with repositioning of the caudal aspect of the nasal septum.
Preoperative gap
between greater and
lesser segments
FIG 67-19 Gap between greater and lesser segments preoperative cleft lip repair.
958 CHAPTER 67 Techniques for Cleft Lip Repair
Postoperative narrowing of
gap between greater and
lesser segments
FIG 67-20 Reduction of gap between greater and lesser segments postoperative cleft lip repair.
A Incision
B
FIG 67-21 A and B, Raising a vomer flap into the anterior hard palate.
A Exposed bone
B
FIG 67-22 A and B, Insetting a vomer flap into the anterior hard palate.
Anterior Hard Palate THE SOUTH WALES CLEFT TEAM PROTOCOL FOR
A vomer flap is raised and inset into the cleft margin (Figure CLEFT LIP REPAIR: ADVANCEMENT/ROTATION LIP
67-21) to close the anterior hard palate at the time of repair of REPAIR WITH AN INFERIOR TRIANGULAR FLAP
the cleft lip to establish continuity of nasal floor closure (Figure
67-22). There may be some narrowing of the width of the pos- The authors close the cleft lip at 3 months old and the repair
terior cleft palate following vomer flap closure. involves the following key steps:
CHAPTER 67 Techniques for Cleft Lip Repair 959
1. An advancement/rotation repair of the cleft lip incorporat- side to the cleft side peak of the cupid’s bow curving parallel
ing an inferior triangular flap addressing the medial shorten- to and just above white line. It is curved medially and turns
ing and lateral displacement while restoring normal anatomy, across the vermilion through 90 degrees at the cupid’s bow
lip length, and symmetry peak and extends just past the wet-dry mucosal junction.
2. Achieving a functional muscular repair by restoring the 4. The incision on the lateral side extends from the alar base
displaced muscles to their correct anatomical position and along the junction of the nasal and lip skin to meet the
recreating the muscular rings of mid and lower face mucosa at 90 degrees (Figure 67-26). The incision then
3. Using a vomer flap to repair the anterior hard palate in extends from this point along the white roll parallel to the
continuity with the repair of the floor of nose skin/mucosal junction to the meet the upper point of the
4. Performing a McComb’s nasal dissection if required to lateral triangular flap.
release the lower lateral cartilage, allowing it to sit in a correct 5. An inferior triangular flap is incorporated along the incision
anatomical position in lateral element and inset into a backcut in the medial
5. Straightening of the caudal aspect of the nasal septum to element to lengthen the deficient medial element (Figure
place the septum in its correct central anatomical position 67-27). The triangle and the backcut must be the same
The key surgical steps in the authors’ surgical protocol are as height above the white roll. The addition of an inferior tri-
follows: angle to the advancement/rotation repair of a cleft lip allows
1. Right complete cleft lip: Identification of key surgical land- full restoration of length without the overextension of the
marks show on an illustration and clinical photograph medial incision under the base of columella. The lip length
(Figure 67-23). must not be shorter than normal side at end of surgery.
2. The skin markings include the following key landmarks 6. Advancement of the lateral side to align with the rotated
(Figure 67-24): short medial element (Figure 67-28).
• Cupid’s bow markings: Non-cleft side peak, trough and 7. The intranasal incisions are illustrated in Figure 67-29.
peak on the cleft side (a point on the cleft side equidistant The incision on the medial element extends at a tangent
from the trough of the cupid’s bow) to the curved incision, extending into the floor of the nose along
• First change in the appearance of white roll on the lateral the nasal/oral mucosal junction. It will connect to the vomer
element: The point of first change of the white roll and flap, and the raised flap will form the medial floor of the nose.
where the white roll and vermilion start to converge The incision on the lateral element is a continuation of the
• Base of columella: Remember it is rotated lateral element incision into the nose parallel to the junction of
• Alar base: The inferior lateral point the skin-mucosal junction. This incision extends to the alveolus
3. Curved incision along the short medial element (Figure and sits just below the inferior turbinate.
67-25): The aim is to place the scar in the line of the natural 1. Outline of sterile mucosa: The incisons are extended across
philtral ridge. The medial side of the philtrum must be the white roll medially and laterallly at 90 degrees to the
lengthened to match the non-cleft length. The incision does white roll. They extend though the wet–dry junction and
not extend along the base of columella at its superior aspect. then up into the nose. The mucosa outlined is the sterile
The incision extends from the base of columella on the cleft mucosa.
No extension across
base of columella
Incision extends across white roll
at 90 to cupid’s bow peak
Base of columella
Alar base
Peak of cupid’s bow on medial
side—equidistant from the trough First change in
compared with the non-cleft side the white roll on
lateral element
Peak and trough of
cupid’s bow
Nasal skin
Short philtral length on Incision that separates nasal
the medial element skin from the lip skin
Normal philtral length on Lip skin
the non-cleft side Incision extending from the
junction of lip/nasal skin
with mucosa along the white
roll to the point of first change
in the white roll
2. Advancement rotation skin markings with an inferior tri- 4. Subperiosteal dissection: This is performed if the transverse
angle (Figure 67-30): The vermilion border is tattooed with nasalis muscle will not reach the ANS. After the muscle
ink; these points act as landmarks to allow accurate recon- dissection is done, an incision is made in the buccal sulcus
struction of the white roll. Local anesthetic is infiltrated and up to the nasal margin of the cleft. A wide subperiosteal
marking incised. The sterile mucosa is excised, and the dissection is done from the vestibule on the cleft side over
muscle edges are identified along both sides of the cleft the piriform rim, nasal bone, and infraorbital and malar
margin. regions to lift the facial mask, taking care to protect the
3. Muscle dissection: The muscle is dissected on both sides of infraorbital nerve (Figure 67-33).
the cleft to separate the muscle from the mucosa and dermal 5. McComb nasal dissection26: This should be performed as
layers. On the medial side, dissection of the muscle is required if the lower lateral cartilage will not sit in the
carried out to relieve the abnormal attachments from ANS correct position when the nasal muscle is approximated.
and the columella allowing lengthening and rotation of the Access is gained to the lower lateral cartilages through a
skin deficiency on the medial element (Figure 67-31). On medial approach, allowing blunt dissection of the cartilage
the lateral side, muscle dissection is done to identify and from the overlying skin/nasal mucosa. The plain of dissec-
mobilize the head of the transverse nasalis and the length tion is subdermal and submucosal. The lower lateral carti-
of orbicularis (Figure 67-32). lage can also be approached from the lateral aspect if
CHAPTER 67 Techniques for Cleft Lip Repair 961
Sterile
Sterile
mucosa on
mucosa on
lateral side
medial side
FIG 67-31 Dissection of muscle on the medial side. ANS, Anterior nasal spine.
required, but this isn’t commonly performed (Figure from its attachment to the nasal spine and maxillary crest,
67-34). The McComb dissection reduces the buckling effect straightened and repositioned centrally (Figure 67-36).
of the lateral crus of the lower lateral cartilage, allowing it 7. Nasal floor reconstruction: The nasal floor is reconstructed
to sit in a more natural position. by suturing the hair-bearing nasal mucosa on both sides,
6. Septoplasty: Correction of the caudal aspect to the deviated posteriorly closing the lateral nasal floor to the vomer flap
nasal septum provides stability and exact positioning of the (Figure 67-37).
previously lifted alar crus of the cleft side and nasal tip. This 8. Suturing of transverse nasalis to ANS/septum: This is
allows the nose to grow in a balanced way with equal muscu- done to secure the position of the base of the septum
lar force being exerted on both sides. The caudal aspect of the (Figure 67-38).
nasal septum is then carefully isolated and freed through the 9. Natural approximation of orbicularis oris: The orbicularis
same cleft incision by splitting and raising the perichon- is approximated and sutured to a natural position main-
drium on both sides (Figure 67-35). The septum is detached taining the muscle length (Figure 67-39).
962 CHAPTER 67 Techniques for Cleft Lip Repair
Muscle dissection
identifying head of
transverse nasalis
Subperiosteal dissection
extending from piriform rim
to malar prominence
Nasal cartilage
Medial blunt
dissection
Exposure of the
caudal aspect of
the deviated nasal
septum
FIG 67-35 Exposure of the deviated caudal aspect of the nasal septum.
FIG 67-36 Detachment and straightening of caudal aspect of nasal septum. ANS, Anterior nasal
spine.
964 CHAPTER 67 Techniques for Cleft Lip Repair
Reconstruction of
floor of nose
Suturing of
transverse
nasalis to
ANS/septum
10. Skin closure: Tension-free skin closure is performed (Figure lateral side.27 The incision is then bowed in a curvilinear fashion
67-40). This is made possible by the subperiosteal dissec- near the base of the columella crossing the philtrum toward the
tion, radical mobilization, and suturing of the transverse far lateral extent of the columellar base (Figure 67-41).28 In one
nasalis and orbicularis muscles. form or another, it is the most widely practiced method today.
The rotation advancement technique relies on a “cut as you
COMMON TECHNIQUES OF CLEFT LIP REPAIR go” strategy that allows continuous modifications during the
design and execution of the repair. It does not adhere to strict
Millard Cleft Lip Repair geometrical principles or measurements.
Flap Design However, it may leave a scar crossing the midline at the base
The Millard cleft lip repair is based on a rotation flap on the of the columella and cause shortening of the lip on the cleft side
medial cleft side coupled with an advancement flap on the cleft with resultant vermilion notching and whistle deformity.
CHAPTER 67 Techniques for Cleft Lip Repair 965
Natural
approximation of
orbicularis oris
Fisher often adds a small inferior triangle just above the and use of geometric and curvilinear incisions to approach a
cutaneous roll for additional rotation and feels that this accen- vertically oriented closure.
tuates the pout of the lip. Although this technique is included
in the category of rotation/advancement repairs, it is clearly a
hybrid of multiple principles, including triangle-flap techniques REPAIR OF THE INCOMPLETE CLEFT LIP
The repair of the incomplete cleft lip follows the same principles
as outlined for the repair of the complete cleft lip. The incision
is modified to divide the nasal skin from the lip skin in a line
along the base of the nasal sill (Figure 67-47). The texture of
the nasal skin is different from the texture of the skin of the lip,
and the incision line is placed between the junction of both skin
types. The texture of the skin that is excised is abnormal due to
the lack of underlying muscle insertion. A small wedge excision
into the nasal sill may be used to prevent a prominence of scar
tissue from developing in this area. The authors do not include
this extension into the nasal sill, because it may lead to nostril
narrowing and flattening of the nasal sill. If a tissue prominence
should develop, it can be easily treated with a wedge excision at
FIG 67-46 Fisher repair. a later date.
Lip skin
Sterile mucosa
to be excised
C
B
FIG 67-47 A, An incomplete left side cleft lip. B and C, Preoperative skin markings for an incom-
plete left side cleft lip repair.
968 CHAPTER 67 Techniques for Cleft Lip Repair
Nasal skin
Advancement of the
Lip skin lateral elements
Suture skin of
floor of nose
Suture through
transverse nasalis
Reconstruction of both
halves of the orbicularis oris
across the premaxilla
FIG 67-54 Functional reconstruction of orbicularis oris muscle repair under the prolabium.
definitive repair. This inevitably delays any attempt at syn- is technically demanding for both the orthodontist and the
chronous repair of the lip and nose, and there is no evidence patient’s carers, and it would benefit from being submitted
that it improves long-term outcome. The authors’ preferred to a randomized controlled trial before being universally
method of repair of bilateral cleft lip is a synchronous repair adopted as a useful adjunct to the already considerable
at 3 to 4 months of age, but they recognize that occasionally burden of care suffered by patients with bilateral clefts. The
in very wide clefts it may not be technically possible to repair use of NAM as an adjunct to primary repair of the lip and
the muscles completely. nose has been a recent development that may help improve
• Pre-surgical orthopedics: Formal surgical repair is often nasal outcome.
preceded by pre-surgical orthopedics to retroposition the
premaxilla and enable a tension-free repair of the lip.40 Pre-
surgical orthopedics may be of benefit in the surgical repair PITFALLS
of bilateral cleft lip by helping achieve complete reconstruc- • Highly specialized surgery is necessary in the early months of life to
tion of the muscles across a severe cleft with a protuberant maximize function of the face and oro-pharynx. Deficiencies of facial
premaxilla and by lengthening the columella. Although there and dental development, speech and hearing remain frustratingly
common and may be accompanied by psycho-social issues.
is no doubt that it facilitates the repair and is still widely
• Evidence for and against the use of the vomer flap is conflicting its
used, there is no evidence that it improves outcome.41 use serves to narrow the hard palate as it heals by secondary inten-
• Nasoalveolar molding (NAM): This is a form of pre-surgical tion. However, avoiding its use would cause less scarring and leave
orthopedics that expands the columella and repositions the the alveolus in pristine condition for bone grafting. Ultimately this
premaxilla. Columellar lengthening allows the cartilages of might lead to better facial growth.
the nasal tip to be reshaped.42-44 Early studies have shown • Repairing the soft palate at the time of lip repair also encourages the
cleft in the hard palate to narrow due to muscular action. However,
that NAM does this effectively before operation. Although
this may increase the risk of a fistula developing at the hard/soft
early results with preoperative NAM are promising, objective palate junction.
analysis of long-term outcome has not yet been reported. It
CHAPTER 67 Techniques for Cleft Lip Repair 971
REFERENCES 21. Millard RD, Jr: Refinements in rotation-advancement cleft lip technique.
Plast Reconstr Surg 33:26–38, 1964.
1. Stanier P, Moore GE: Genetics of cleft lip and palate: syndromic genes 22. Cronin TD: Surgery of the double cleft lip and protruding premaxilla.
contribute to the incidence of non-syndromic clefts. Hum Mol Genet Plast Reconstr Surg 19:389–400, 1957.
13:73–81, 2004. 23. Randall P: Triangular flap operation for the primary repair of unilateral
2. Sperber GH: Craniofacial embryogenesis: normal developmental clefts of the lip. Plast Reconstr Surg Transplant Bull 23(4):331–347, 1959.
mechanisms. In Mooney MP, Siegel MI, editors: Understanding 24. Reddy GS, Reddy RR, Pagaria N, et al: Afroze incision for functional
craniofacial anomalies: the etiopathogenesis of craniosynostosis and facial cheiloplasty. J Craniofac Surg 20(Suppl 2):1733–1736, 2009.
clefting, New York, 2002, John Wiley and Sons, pp 31–60. 25. Liao YF, Lee YH, Wang R, et al: Vomer flap for hard palate repair is
3. Breitsprecher L, Fanghanel J, Waite P, et al: Gibt es neue Erkenntnisse zur related to favorable maxillary growth in unilateral cleft lip and palate.
Embryologie und funktionellen Anatomie der humanen mimischen Clin Oral Investig 18(4):1269–1276, 2014.
Muskulatur und der Oberlippe? Mund Kiefer Gesichtschir 6:102–110, 26. McComb H: Treatment of the unilateral cleft lip nose. Plast Reconstr Surg
2002. 55:596–601, 1975.
4. Diewert VM, Losanoff S: Animal models of facial clefting: experimental, 27. Millard DR, Jr: The primary camouflage of the unilateral harelook. In
congenital, and transgenic. In Mooney MP, Siegel MI, editors: Transactions of the international society of plastic surgeons, Stockholm,
Understanding craniofacial anomalies: the etiopathogenesis of 1957, First Congress, pp 160–166.
craniosynostosis and facial clefting, New York, 2002, John Wiley and Sons, 28. Millard DR, Jr: Complete unilateral clefts of the lip. Plast Reconstr Surg
pp 251–272. 25:595–605, 1960.
5. Johnston MC, Bronsky PT: Craniofacial embryogenesis: abnormal 29. Markus AF, Delaire J: Functional primary closure of cleft lip. Br J Oral
developmental mechanisms. In Mooney MP, Siegel MI, editors: Maxillofac Surg 31:281–291, 1993.
Understanding craniofacial anomalies: the etiopathogenesis of 30. Delaire J: [Primary cheilorhinoplasty for congenital unilateral
craniosynostosis and facial clefting, New York, 2002, John Wiley and Sons, labiomaxillary fissure. Trial schematization of a technic]. [Article in
pp 61–124. French]. Rev Stomatol Chir Maxillofac 76(3):193–215, 1975.
6. Gorlin RJ, Cohen MM, Jr, Hennekam RCM: Syndromes of the head and 31. Pfeifer G: Lip corrections following earlier cleft surgery by way of
neck, ed 4, New York, 2003, Oxford University Press. wave-line incisions. Dtsch Zahnarztl Z 25:569–576, 1970.
7. Gorlin RJ, Cohen MM, Jr: The orofacial region. In Wigglesworth JS, 32. Reddy GS, Reddy RR, Pagaria N, et al: Afroze incision for functional
Singer DB, editors: Textbook of fetal and perinatal pathology, ed 2, cheiloplasty. J Craniofac Surg 20(Suppl 2):1733–1736, 2009.
Malden, MA, 1998, Blackwell Science. 33. Tennison CW: The repair of the unilateral cleft lip by the stencil method.
8. Ferguson MW: Developmental mechanisms in normal and abnormal Plast Reconstr Surg 9:115–120, 1952.
palate formation with particular reference to the aetiology, pathogenesis 34. Randall P: A triangular flap operation for the primary repair of unilateral
and prevention of cleft palate. Br J Orthod 8:115–137, 1981. clefts of the lip. Plast Reconstr Surg 23:331–347, 1959.
9. Carinci F, Pezzetti F, Scapoli L, et al: Recent developments in orofacial 35. Rose W: On harelip and cleft palate. London: H.K. Lewis; 1891.
cleft genetics. J Craniofac Surg 14:130–143, 2003. 36. Thompson JE: An artistic and mathematically accurate method of
10. Kerrigan JJ, Mansell JP, Sengupta A, et al: Palatogenesis and potential repairing the defect in cases of hairlip. Surg Gynecol Obstet 14:498–504,
mechanisms for clefting. J R Coll Surg Edinb 45:351–358, 2000. 1912.
11. Sykes JM, Senders CW: Facial plastic surgery: cleft lip and palate, 37. Delaire J: Significance of primary rhinoplasty: technical considerations.
New York, 1993, Thieme Medical Publishers. Chir Pediatr 24:286–296, 1983.
12. Veau V: Division palatine, Paris, 1991, Masson. 38. Mulliken JB: Correction of the bilateral cleft lip nasal deformity:
13. Fogh-Andersen P: Inheritance of cleft lip and cleft palate, Copenhagen, evolution of a surgical concept. Cleft Palate Craniofac J 29:540–545, 1992.
1942, Nyt Nordisk Forland-Arnold Busck. 39. McComb H: Primary repair of the bilateral cleft lip nose: a 4-year review.
14. Kernahan DA, Stark RB: A new classification for cleft lip and palate. Plast Reconstr Surg 94:37–50, 1994.
Plast Reconstr Surg 22:435–441, 1958. 40. Ross RB, MacNamera MC: Effect of presurgical infant orthopedics on
15. Pfeifer G: Classification of Northwestern German Jaw Clinic in treatment facial esthetics in complete bilateral cleft lip and palate. Cleft Palate
of patients with cleft of lip, alveolus and palate. Presented at Second Craniofac J 31:68–73, 1994.
Hamburg International Symposium, Stuttgart, Germany, 1966. 41. Berkowitz S, Mejia M, Bystrik A: A comparison of the effects of the
16. Kernahan DA: The striped Y: a symbolic classification for cleft lip and Latham-Millard procedure with those of a conservative treatment
palate. Plast Reconstr Surg 47:469–470, 1971. approach for dental occlusion and facial aesthetics in unilateral and
17. Kriens O: LAHSHAL: an easy clinical system of cleft lip, alveolus bilateral complete cleft lip and palate. Part I. Dental occlusion. Plast
and palate documentation. In Kriens O, editor: Proceedings of the Reconstr Surg 113:1–18, 2004.
advanced workshop: “what is a cleft?”, Stuttgart, Germany, 1989, 42. Grayson BH, Santiago PE, Brecht LE, et al: Presurgical nasoalveolar
Thieme. molding in infants with cleft lip and palate. Cleft Palate Craniofac J
18. Fára M: Anatomy and arteriography of cleft lips in stillborn children. 36:486–498, 1999.
Plast Reconstr Surg 42:29–36, 1968. 43. Grayson BH, Cutting CB: Presurgical nasoalveolar orthopedic molding
19. Mooney MP, Siegel MI, Kimes KR, et al: Premaxillary development in in primary correction of the nose, lip, and alveolus of infants born with
normal and cleft lip and palate human fetuses using three-dimensional unilateral and bilateral clefts. Cleft Palate Craniofac J 38:193–198, 2001.
computer reconstruction. Cleft Palate Craniofac J 28:49–54, 1991. 44. Lee CT, Garfinkle JS, Warren SM, et al: Nasoalveolar molding improves
20. Delaire J: Theoretical principles and technique of functional closure of appearance of children with bilateral cleft lip-cleft palate. Plast Reconstr
the lip and nasal aperture. J Maxillofac Surg 6(2):109–116, 1978. Surg 122:1131–1137, 2008.