TOXICOLOGY -Antidotes ,

active principles, common

names
DR VISHWAJEET SINGH
 TOXIC AGENT ANTIDOTES
Antidotes
PCM N-acetylcysteine

Anticholinergics (dhatura, Physostigmine

atropine)
Anticholinesterases (OPC Atropine
& carbamates)
BZD Flumazenil

Opioids Naloxone

Cyanide Lilly’s kit (amyl

nitrite+sodium
nitrite+sodium thiosulfate)
Methanol & ethylene glycol Ethanol / fomepizole
Antidotes
❑Arsenic( ) – BAL (i.m)
❑Oxalic acid & HF6- calcium gluconate (i.v)
❑Yellow phosphorus- Vit K
❑Wilsons disease- ( TOC= Zinc + Trientene)…….penicillamine can
be used.
❑Iron – desferrioxamine
❑Snakes – polyvalent ASV
❑Strychnine – diazepam
Active principles-in vegetable poisons
❑Abrus precatorius- Abrin
❑Semecarpus anacardium- Semecarpol & Bhilawanol
❑Ricinus communis( castor)- Ricin( not present in castor oil, so oil is
non toxic)
❑Croton tiglium( jamalgota)- Crotin( oil is toxic)
❑Capsicum annum( chilli)- capsaicin
❑Calotropis gigantea ( madar)- calotoxin, uscharin, calactin
Active principles
❑Strychnous nux vomica( )– strychnine,
brucine, loganin
❑Gelsemium- gelsemine, scopoletin

❑Dhatura( ) – atropine, hyoscyamine,

scopolamine
 Common names of poison:
Aconite – blue rocket, devil’s helmet, monks hood, wolfsbane, meetha
bish.

Abrus precatorius - ratti, gunchi, crab’s eye, jequirity, rosary pea.

Cocaine( vasoconstrictor)- white lady, coke, snow, Cadillac, she.

Phencyclidine ( NMDA receptor antagonist like KETAMINE)- angel dust
Cannabis- weed, mary jone(M.J), purple haze.

Heroin ( diacetylmorphine)– smack, junk, brown sugar

MDMA- ecstasy, rave drug, club drug