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frequencies penetrate deeper tissue at the expense of resolu-
tion, whereas higher frequencies improve resolution but cannot Table 197-1 Common Definitions
penetrate deeper structures. Window—soft tissue where transducer is placed to interrogate
PART VII ■ The Practice of Emergency Medicine / Section One • Clinical Practice and Administration
M-mode or motion mode displays received waves over both tissue in the body
time and distance and is used to calculate rates, speeds, and Anechoic—without sounds (black)
distances by sending a steered one-dimensional line across Echogenic—with sounds (white)
tissue. The most familiar display is B-mode or brightness
Hyperechoic—with more reflected sounds than adjacent tissue
mode, which graphs the amplitude of reflected US waves as (more echogenic)
shades of gray from black to white on a monitor screen. As
Hypoechoic—with less sound than adjacent tissue (less
sound hits reflective interfaces, it returns to the transducer at echogenic)
higher amplitudes than waves that continue through tissue. In
Shadowing—sound blocked by a reflective barrier
addition, sound can be attenuated, refracted, and reverberated
Enhancement—more echogenicity due to increased velocity of
away from the transducer. These reflections or lack thereof
sound, typically behind a fluid-filled structure such as the
create a brightness graph that is depicted in two planes creat- bladder or gallbladder
ing the two-dimensional image. One can adjust the brightness
Reverberation—an artifact that results from multiple reflections
of the image by changing the overall gain or change the amount at a given interface, often in parallel
of gain at certain depths, which is called time-gain compensa-
Mirror image—a propagation speed artifact that repeats images
tion (TGC). This allows for a more discrete amplification of that are beyond a strong reflector (e.g., diaphragm), creating a
sound at different levels. By increasing overall gain or ampli- mirror image
fication and TGC at different levels, one can adjust for the loss Lateral cystic shadowing—a refraction artifact seen on the edge
of returning information. of cystic structures causing an artificial shadow
US resolution can be described as axial, in the long axis of Beam width artifact—a volume-averaging artifact causing
the transducer, or lateral, perpendicular to the long axis of artifactual echoes in the inferior aspect of anechoic structures
the transducer. Typically, higher probe frequencies produce or spaces
higher axial resolution. The focus of the transducer is the
image area where the US beam produces the best lateral reso-
lution. The area from the probe to the focus is called the near have controls for gain, depth, and freeze and have print or
field, and that from the focus to the end of the image is called acquire image controls. Additional controls including TGC,
the far field. The best imaging with maximum reduction in frame rate, measurement, dynamic range, M-mode, power
artifacts occurs at the focus. Doppler, color directional Doppler, spectral Doppler, patient
Focal zones can be increased for more resolution, but frame ID, transducer selection, and image review. Images are pro-
rate (the speed at which the screen updates the image) will duced in digital stills, digital video clips, thermal paper stills,
decrease, causing a slow-motion image that is poor for imaging or DVD or video recordings.
moving tissues. One can also change from a sector transducer Modern multifrequency probes can select among several US
(a curved abdominal or phased array transducer) to a linear frequencies to maximize either tissue penetration or image
transducer for better lateral resolution on the edges of the quality depending on the application. Probe design and foot-
transducer. prints (the actual transducer surface area touching the patient)
Some machines allow the adjustment of dynamic range, can be divided into three categories: flat linear array probes,
which is the ratio of initial intensity and final intensity of curved linear array probes, and phased array probes. Flat linear
returning echoes. Adjusting dynamic range allows for more probes give a square or rectangular picture with excellent
contrast (e.g., echocardiography) or more gray scale (e.g., soft lateral resolution at the expense of width of field. Curved
tissue). Harmonics is another technology that listens for mul- linear array probes, which give a wider field of view at the
tiples of the frequency sent out and often cleans up images expense of lateral resolution, are usually used for deep tissue
near the screen such as in the gallbladder, apex of the heart, penetration applications, such as evaluation for pregnancy or
or soft tissue of skin. abdominal aortic aneurysm. The endocavitary probe is a highly
Doppler US shows the velocity of moving structures, typi- curved linear array probe that is most commonly used for
cally red blood cells, thus representing flow. Color flow Doppler endovaginal evaluation. Phased array probes offer a smaller
shows direction (by red or blue colors representing flow in footprint than curved linear array probes and were originally
opposite directions) and velocity of flow (by degrees of bright- developed for cardiac evaluations, but they can also be used
ness of the color, where lighter is higher velocity). Power for abdominal studies. They offer excellent image quality for
Doppler or power angiography is also a representation of veloc- the evaluation of moving structures but with worse resolution
ity of flow, but it describes only the presence of flow and not of static structures.
direction.
Gray scale US has the best resolution when the direction of ■ APPLICATIONS AND CATEGORIZATION
the probe and sound waves are perpendicular to the object
because the sound is reflected back up to the transducer. In 1994, SAEM categorized US applications broadly into
Doppler US has the best resolution with the probe parallel or abdominal, cardiac, obstetric/gynecologic, and special applica-
less than 60 degrees from the direction of blood flow. This tions.18 In 2001, ACEP developed specialty-specific guidelines
often means realignment by tilting of the probe to create that categorized applications more narrowly to include trauma,
better imaging based on the mode of US. pregnancy, abdominal aortic aneurysm (AAA), and cardiac for
Other US terms and artifacts commonly used are listed in pericardial effusion and cardiac activity, biliary, renal, and pro-
Table 197-1. cedural applications.1 Recent studies have investigated emer-
gency US in diagnosing deep vein thrombosis (DVT) and
■ EQUIPMENT pneumothorax.4 New applications include soft tissue, ocular,
and musculoskeletal studies.27-32 Therapeutic applications of
A variety of US machines are available, including palm size, transcranial Doppler are being studied by emergency
laptop, cart based, and combination devices. US machines physicians.33
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The most common uses of US by community emergency
departments in decreasing order are trauma, cardiac (cardiac
arrest and pericardial effusion), AAA, pelvic, biliary, proce-
Trauma Ultrasound
The trauma US exam is also called the focused assessment
with sonography in trauma (FAST) examination.4,36,37 The
trauma examination originally focused on the peritoneal space, Figure 197-1. Free fluid in the peritoneum in Morison’s pouch seen from
as an evaluation for hemoperitoneum, using the right flank, right flank.
left flank, and pelvic windows for detection of dependent
peritoneal fluid and pleural effusion.38,39 Newer versions
include the EFAST (extended FAST) for the evaluation of colic gutters inferior from the flank views and medial from the
potential pneumothorax and FASTER for evaluation of the iliac spine to visualize free fluid surrounding the bowel.47
extremities.40 The typical cardiac views include the transverse subcostal
The FAST exam is based on the premise that fluid within images, which visualize the four cardiac chambers and pericar-
the peritoneum circulates throughout the abdomen and pelvis dial space, whereas the sagittal subcostal view assesses the
and settles in dependent spaces.41,42 The volume of fluid pericardial space and the inferior vena cava with regard to its
required for a positive US depends on the site of injury and collapsibility and diameter, indicating right heart pressures. A
site of sonographic detection but generally 250 mL or greater good alternative in patients with long chest walls or obesity is
is required, and nearly 600 mL of fluid is necessary to cause a the parasternal view, which assesses the anterior and posterior
positive flank stripe when fluid is from the pelvis.43 Pericardial pericardial spaces.
fluid is contained within the parietal and visceral pericardium. For pleural fluid, the superiorly angled flank views allow
Once a certain volume is reached, the pressure in the pericar- visualization of the costophrenic angles. The evaluation for
dial space increases exponentially, causing pericardial tampon- pneumothorax utilizes either a low-frequency probe at a
ade.44 Generally, 50 mL is required to cause a hemodynamic shallow depth or, more typically, a high-frequency probe for
compromise in a patient without prior pericardial inflamma- better resolution, placed at the anterior chest in the second
tion. However, tears in the pericardium that communicate intercostal space for anterior pneumothorax and at the axilla
with the pleural space or even the peritoneum can cause false- for large pneumothoraces and pleural effusion.
negative exams. Pleural fluid can be detected by US, but this The sensitivity of the FAST exam ranges from 60 to 99%,
is dependent on the position of the body.45 Pneumothorax and its specificity ranges from 80 to 99%.48-50 The large range
detection is based on the absence of the normal sonographic of sensitivity is related to the comparative gold standard used
sliding of the visceral and parietal pleura. for each study, with clinical endpoints suggesting higher accu-
The indications for the torso trauma US examination (often racy. The trauma US does not capture every peritoneal injury,
called the EFAST) include the need to detect any of the fol- although the need for intervention on undetected injuries has
lowing in an injured or ill patient: pathologic free intraperito- not been studied. Randomized, controlled trials show reduced
neal fluid (typically hemoperitoneum, uroperitoneum, bile, or morbidity, time to operating room, and charges for patients
bowel contents), hemopericardium, hemothorax, or pneumo- with US use during resuscitation,51,52 and a positive US
thorax.46 Typically, fluid in the peritoneum, pericardium, and increases the odds ratio of laparotomy.53
pleural cavity is anechoic, but it can have echogenicity with Patients with traumatic pericardial effusions have reduced
clotting, depending on the age of the clot. Compared with times to operative management and reduced mortality rates
other fluid-filled structures in the abdomen and pelvis, perito- with US,44 but the mediastinal injuries more common in blunt
neal free fluid generally has sharp edges and an irregular shape, trauma have not been assessed without transesophageal
whereas most visceral or vascular structures have intrinsically echocardiography.54 Pleural effusion has been studied with
smooth oval contours and less abrupt edge detail. variable accuracy.55 US diagnoses pneumothorax with excel-
The FAST technique uses a low- to middle-frequency lent sensitivity and specificity compared to plain chest x-ray
probe (2–5 MHz) to evaluate dependent peritoneal spaces, and variable accuracy compared to computed tomography
pleural spaces, and the pericardium. Within the peritoneum, scanning.56
dependent spaces include the following, grouped by tissue There are certain patient populations in whom FAST evalu-
window: right flank—this evaluates the hepatorenal space, also ation has limited performance. In patients with penetrating
called Morison’s pouch (Fig. 197-1), the right subphrenic chest injuries, the use of the FAST exam seems to be effica-
space, and the right costophrenic angle; left flank—this evalu- cious for both pericardial and nearby peritoneal injuries,57
ates the perisplenic space between the diaphragm and spleen, but in patients with purely anterior penetrating trauma to
the splenorenal space, the perirenal space, and the left sub- the abdomen, the sensitivity of trauma US is poor because
phrenic space; and suprapubic view—this view is performed significant bowel injuries can occur without significant
by placing the transducer superior to the pubic bone with a hemoperitoneum.58,59
full bladder to visualize the pouch of Douglas in females and The accuracy of the FAST exam in children is very similar
the retrovesical space in men. Extra views include the para- to that in adults, but caution is advised because many pediatric
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injuries can be observed or treated nonoperatively with angi- lower abdomen suprapubically. Ideally, the patient has a full
ography.60 In obstetric patients, the few observational studies bladder, which provides a sonographic window, but this may
that have been performed have shown reasonable sensitivity not be necessary if the uterus is large or the patient is thin.
PART VII ■ The Practice of Emergency Medicine / Section One • Clinical Practice and Administration
and specificity, although abruption and fetal viability may Advantages of the transabdominal technique include wider
necessitate an earlier operative course.61 field of view, detection of large pelvic masses, and greater
In patients with pelvic fractures, there have been mixed depth of field. In the endovaginal technique, the transducer is
results, with sensitivity from 20 to 80%.62-64 More important, placed in the vagina, optimally with an empty bladder to visu-
the detection of free fluid in an unstable patient with a pelvic alize the same structures. Endovaginal transducers are high
fracture may be due to uroperitoneum from bladder injury frequency, providing excellent axial resolution but poor pen-
rather than hemoperitoneum from vascular injury, clouding etration of distant structures. Early intrauterine yolk sacs and
the decision for laparotomy versus pelvic embolization.64 In fetal poles within gestational sacs may be detected more
addition, retroperitoneal injuries to the genitourinary tract are clearly, and ectopic pregnancies can be identified with more
not assessed with four-quadrant FAST exam. accuracy. Endovaginal US can detect small (7 mL) amounts of
peritoneal fluid. Endovaginal US in the hemodynamically
Pelvic Ultrasound compromised patient has replaced culdocentesis for detection
of ruptured ectopic pregnancy.
Pelvic US by emergency physicians was initiated to address one Emergency physician-performed pelvic US has reduced the
of the epidemics of the modern era—ectopic pregnancy.65-69 morbidity of ectopic pregnancy by shortening the time to diag-
Typically, pelvic US is used to confirm intrauterine pregnancy, nosis and operating room treatment, and it has resulted in
thereby indirectly excluding ectopic pregnancy in the vast greater initial detection of abnormal pregnancy, reduced emer-
majority of patients.70,71 Other uses during pregnancy include gency department patient throughput times, and increased
detection of fetal viability, incomplete abortion, ectopic patient satisfaction with emergency department care.66,68,75-78
pregnancy, and molar pregnancy. Nonpregnancy pelvic US Pelvic US in nonpregnancy states has shown good accuracy
uses include the detection of tubo-ovarian abscesses, masses, for tubo-ovarian abscess and improved decision-making for
and hemoperitoneum in the hemodynamically unstable female patients with right lower abdominal pain.79
patient.72
Indications for sonographic evaluation of the first-trimester Cardiac Ultrasound
pregnant patient include symptoms or signs that suggest an
ectopic pregnancy, molar pregnancy, fetal demise, or for dating The use of cardiac US by emergency physicians is presenta-
the pregnancy. Standard definitions for intrauterine pregnancy tion and symptom specific and focused in nature. Indications
describe a gestational sac with a yolk sac or fetal pole within the include cardiac arrest, possible pericardial effusion, trauma,
fundus of the uterus (Fig. 197-2).70 An embryonic or fetal chest pain, hypotension, and for procedural guidance. Cardiac
demise has US findings of a fetal pole greater than 5 mm US is often combined with other applications to form algo-
without fetal heart rate or a gestational sac greater than 20 mm rithms and protocols for certain symptoms or signs, such as
in diameter without a fetal pole. A molar pregnancy appears as dyspnea or hypotension.
an echogenic, cystic uterus with disorganized echoes and is Cardiac US is performed through the transthoracic and
associated with high β-hCG concentrations without the sono- transabdominal windows using small curvilinear or phased
graphic finding of intrauterine pregnancy. Findings of an ectopic array transducers. Typical views include the subcostal four-
pregnancy include a chorionic ring or gestational sac with chamber and long-axis views, parasternal long-axis view, para-
evidence of a yolk sac or fetal pole outside the uterus or in an sternal short-axis view, and apical four-chamber view. Although
abnormal location in the uterus, such as the cornu or cervix.73 most emergency physicians are very comfortable with the sub-
Excluding the groups of IUP, embryonic demise, molar preg- costal view from the FAST exam, the parasternal long-axis
nancy, and ectopic pregnancy, there is a class called “indetermi- view is a good alternative and good window for left ventricular
nate,” which may account for 20% of pregnant patients assessment.80,81 In addition, the apical four-chamber view pro-
presenting to the ED in the first and early second trimesters. vides excellent comparison of the right and left ventricles in
Heterotopic pregnancies can occur at a rate of 1/5000 and be terms of size and function.
detected by the same techniques and definitions.74 Cardiac US performed by emergency physicians shows good
Pelvic US is performed by either transabdominal or endo- accuracy in detection of pericardial effusion (Fig. 197-3),
vaginal techniques. The transabdominal technique utilizes a
low-frequency transabdominal transducer placed over the
Figure 197-2. Intrauterine pregnancy with fetus on endovaginal scanning. Figure 197-3. Pericardial effusion in subcostal view.
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assessment of left ventricular function, and evaluation of
patients with undifferentiated shock. In addition, aspects of
cardiac US are being used for the assessment of intravascular
Renal Ultrasound
Renal or urinary tract US is one of the early applications for
the diagnosis of urinary obstruction, resulting in hydronephro-
sis. The lack of ionizing radiation and the rapidity of renal US
make it an attractive option for the investigation of unex-
plained flank, back, or groin pain.
The performance of renal US includes biplanar views of the
kidneys with emphasis on dilation of the calyceal system and
pelvis of the respective kidney. In addition, visualization of
the bladder can diagnose secondary hydronephrosis from an
obstructed bladder stone and may demonstrate nonobstructive
bladder jets through the use of Doppler US. The windows for
the two kidneys are very similar to the trauma flank series with
the exception that the patient may be rolled on the opposite
side so that the transducer may be placed more posteriorly on
the back if needed. The bladder view is performed supra Figure 197-7. Deep vein thrombosis with layering clot in popliteal vein
pubically, and calculations of volume may be made with on- seen on compression ultrasound.
machine calculators or by formulas.
Renal US has a sensitivity of 83% and a specificity of 92%
in detecting hydronephrosis (Fig. 197-6).116,117 Genitourinary
tract obstruction protocols have shown great sensitivity in
eliminating renal obstruction from a differential diagnosis.118
Bladder US is useful for detection of a full bladder and the
presence of a Foley catheter and also for procedure guidance
(superpubic aspiration or Foley placement).119-124
normal venous and arterial flow. Absence or a difference in Studies of US-guided subclavian insertion suggest that US
flow from the unaffected side indicates possible torsion, does not contribute to procedural success because of a lack of
whereas increased flow indicates epididymitis. Experienced a convenient window for the subclavian vein. At the location
emergency physicians accurately diagnosed testicular pain where the vein is usually cannulated, visualization is obstructed
with a sensitivity of 95% and specificity of 94% in a study of by the clavicle. However, more laterally, toward the junction
36 patients, which included 3 patients with torsion.174 of the axillary vein and subclavian veins, the vein can be visu-
alized in the chest wall.189,190 Although it may be cannulated
Abdominal Bowel Ultrasound there, the more difficult challenge may be inserting the cath-
eter through the pliable soft tissue of the anterior-superior
The use of bedside US for evaluation of appendicitis, diver- chest.191 The supraclavicular fossa is a window for central line
ticulitis, and other bowel pathology is an area of increasing insertion, and the subclavian and brachiocephalic veins may
interest. There has been variable experience with the use of be imaged from this site.192
graded compression US to detect appendicitis, with reported Emergency physicians are able to use US to insert periph-
sensitivity of 67% and specificity of 92%.175 The novel use of eral intravenous catheters in difficult patients with high success
US to detect diverticular disease and hernias has been rates.193-195 Nurses have also been taught to use US for periph-
described.176,177 eral venous guidance.196,197
Arterial access, including radial artery aspiration and cannu-
Ultrasound for Procedural Guidance lation, is more successful with the use of US guidance.198,199
Numerous other procedures using US guidance have been
In 2001, in response to the Institute of Medicine report “To described in emergency practice. They are listed in Table
Err Is Human,” the Agency for Healthcare Research and 197-2.
Quality (AHRQ) sanctioned a report on actions that may
improve patient safety.178 The report contains a recommenda-
tion for US guidance for internal jugular central line insertion.
Since then, the use of US for procedural guidance has expanded
for almost every known emergency procedure, but especially
vascular access. Table 197-2 Ultrasound Guided Emergency Procedures
There are several key concepts regarding procedural guid-
ULTRASOUND PROCEDURE
ance with US. Procedural guidance can be static or dynamic.179
Static guidance suggests that US has been placed over the Vascular access Central venous access182,210,211
anatomic area, and the area is marked while angle and distance Internal jugular vein
information is noted. Dynamic guidance describes procedures Subclavian near axillary vein
performed with real-time US visualization of the needle enter- Subclavian with superclavicular approach
ing the anatomic area. Femoral vein
There are two approaches to vein cannulation: transverse, Peripheral vein193,197,212
Basilic
where the vein appears as a circular structure on the screen, Brachial
and longitudinal, where the vein appears as a tubular structure Cephalic
along the width of the screen. In the transverse approach, the Forearm veins
probe’s long axis is centered transverse (90 degrees) to the Intraosseus needle213
long axis of the anatomic area, guiding the needle to bisect Arterial cannulation198,214
the probe at its center gives centering and depth information. Radial artery
In the longitudinal axis, the probe is placed along the long Arterial sampling215
axis of the anatomic area, and the needle is introduced in Torso fluid Paracentesis216,217
the long axis of the probe, giving depth and trajectory collections Thoracentesis218
information. Pericardiocentesis219
US guidance for central line insertion has been the most Cardiac Pacer placement220–223
studied application and most advocated use among US-guided Musculoskeletal Arthrocentesis29,224,225
procedures.180-182 Both the AHRQ and the National Institute Hip
for Health and Clinical Excellence have recommended US Knee
guidance for central line insertion.183,184 US guidance for inter- Other joints
Fracture reduction
nal jugular (IJ) central line insertion can be recommended as
Foreign body removal226
a best practice and safe practice.180,185 Tendon sheath injection227
US permits the physician to assess the IJ for overlap with
Soft tissue Abscess drainage228
the carotid artery, vessel diameter, and the presence of luminal Hernia reduction229
clot or vessel obliteration.186 IJ central line insertion has been
Anesthesia Interscalene
studied in the emergency department, intensive care unit, Peripheral nerves
and radiology suite. In the emergency department, there is Axillary192
decreased time to flashback and improved success in the dif- Femoral nerve230
ficult stick patient and improved overall success rate, first Hematoma block
attempt rate, reduced time to insertion, and reduced complica- Airway Endotracheal tube placement231–234
tion rate with US guidance for IJ cannulation. Urinary bladder Superpubic aspiration and cystostomy235–237
Femoral vein insertion has been studied in cardiac arrest Foley guidance238
patients, and improved cannulation rate and reduced compli- Neurologic Lumbar puncture239–243
cations have been reported.187 Several maneuvers can optimize
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Out-of-Hospital Ultrasound: Disasters and ■ INTEGRATION INTO EMERGENCY
Remote Settings MEDICINE PRACTICE