Important Pathways for Digital Edition

Chapter 9:  Regulation of glycolysis

Chapter 9:  Summary of glycolysis (Embden-Meyerhof pathway). Steps

1, 3 and 9 are key enzyems; these reactions are irreversible. Steps 5, 6
and 9 produce energy. Steps 5 and 10 are coupled for regeneration
of NAD+
290 Textbook of Biochemistry— Case Studies

Chapter 9:  Cori’s cycle. Contracting muscles lack oxygen. So pyruvate

is reduced to lactate. This can be reconverted to glucose in liver by
gluconeogenesis

Chapter 9:  Summary of glycolysis and gluconeogenic pathways

 Important Pathways for Digital Edition 291

Chapter 10: Glycogenolysis

Chapter 10: Regulation of glycogen synthesis and glycogen breakdown pathways

292 Textbook of Biochemistry— Case Studies

Chapter 10:  HMP shunt pathway

 Important Pathways for Digital Edition 293

Chapter 12: Beta oxidation of fatty acids

294 Textbook of Biochemistry— Case Studies

Chapter 12: Fatty acid synthase complex

 Important Pathways for Digital Edition 295

Chapter 12:  De novo synthesis of fatty acid (Lynen cycle). Steps 4 and 6 utilise NADPH
296 Textbook of Biochemistry— Case Studies

Chapter 12: Cascade activation of hormone sensitive lipase

 Important Pathways for Digital Edition 297

Chapter 12:  Ketogenesis (ketone body formation)

Chapter 13:  Cholesterol biosynthesis

298 Textbook of Biochemistry— Case Studies

Chapter 15 : Transamination reaction

Chapter 15:  Urea cycle

 Important Pathways for Digital Edition 299

Chapter 16:  Overview of serine metabolism

Chapter 15:  Summary of one carbon metabolism

Chapter 16: Summary of methionine/cysteine metabolism

Chapter 17: Metabolism of arginine/ornithine

Chapter 16:  Overview of glycine metabolism

300 Textbook of Biochemistry— Case Studies

Chapter 18:  Metabolism of tryptophan

Chapter 18:  Phenylalanine / Tyrosine metabolism

 Important Pathways for Digital Edition 301

Chapter 18:  Metabolic fates of amino acids

Chapter 19:  Citric acid cycle

302 Textbook of Biochemistry— Case Studies

Chapter 20:  Electron transport chain

Chapter 21:  Bilirubin – Production and excretion

 Important Pathways for Digital Edition 303

Chapter 36:  Wald’s visual cycle

Chapter 21:  Heme synthesis

Chapter 43: Degradation of purines

304 Textbook of Biochemistry— Case Studies

Chapter 46: tRNA structure

Chapter 44:  DNA structure

Chapter 44:  Semi-conservative replication

 Important Pathways for Digital Edition 305

Chapter 47:  Lac operon

Chapter 55:  Structure of Immunoglobulin

Chapter 49: Recombinant DNA technology

306 Textbook of Biochemistry— Case Studies

Chapter 55:  Hybridoma technique

(for production of monoclonal antibodies)

Chapter 49:  Polymerase Chain Reaction (PCR)