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hormones

wbc - immunity (cytokinase)


high/low production of hormones = disorder happens
2 glands - exocrine and endocrine
-> exocrine = excretes secretory products, directly goes to area where it is needed
-> endocrine = ductless glands
peptides = glycoprotein
over/under secretion = lack of regulation hormone
negative feedback mechanism - to maintain balance of production of hormone

anterior pituitary gland - produce t3 and t4 - hormonal stimuli


to be able to release hormones in particular glands, in order for p3 and p4 to
regulate, they need hypothalamus to stimulate anterior pituitary gland

humeral stimuli - refers to hormones released in extracellular fluid e.g blood or


iron
if glucose level is high, pancreas releases insulin, lowers the glucose level in
blood

Neural stimuli - nervous system stimulates glands to release hormone


epinephrine - stress response in adrenal cortex (fight/flight mode)

pituitary gland = master gland


uses info from the brain to secrete/produce hormone where it is needed
hypothalamus releases releasing factor to stimulate the pituitary gland to
stimulate the adrenal gland

hyperfunction can lead to disorders


t3 and t4 = contains iodine atoms, absorption takes place in intestines

thyroid releasing factor - secrete thyroid hormone T4 and T3


pituitary w/ help of thyroid-stimulating hormone to secret more t3 and t4 needed in
our blood
a negative feedback mechanism regulates hormones to maintain balance
low blood = pituitary release stimulating factor
T4 - maintains body metabolism
T3 - potent than T4 (5x stronger) both t3 and t4 maintain body metabolism
thyrocalcitonin - regulates calcium in our bones

too much t3/t4 - hyperthyroidism


secretion not treated causes coma/death

normal regulation of hormones


hypothalamus or anterior pituitary -main problems

adrenal cortex - release steroid hormones


catecholamines - fight or flight hormones -> adrenaline
the hypothalamus will release corticotrophin (adrenal gland)
corticitrophin release to stimulate anterior pituitary gland to release adreno
corticotrophine
ACTH - anterior pituitary gland -> controls regulation

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