DRUG STUDY

Name of Patient: Patient R.C Date of admission:02/14/2022 Room: DR-Bed2

Age:38 y.o Sex:Female Civil Status:Married Attending Physician:Dr. Libres

CLASSIFICATION / NURSING
DRUG NAME INDICATION CONTRAINDICATIONS SIDE EFFECTS/
MECHANISM OF RESPONSIBILITY
ADVERSE EFFECTS
ACTION
Brand Name: Classification: A. Essential ● Allergy to ACE Side Effects: 1. Introduce yourself to the
Apresoline Antihypertensive drug Hypertension inhibitors. Prevent ● chest pain, mother and support
severe hypersensitivity ● fast heart rate, person.
Generic Name: Mechanism of Action: B. Severe reactions. 2. Verify the correct patient
Hydralazine Hydralazine is an Essential ● Renal impairment. ● headache, using two identifiers.
antihypertensive medication Hypertension Decreased renal blood ● vomiting, 3. Assess baseline
Dosage: used to treat high blood flow effect of these maternal vital signs.
5mg IVTT pressure. It is a peripheral C. Heart failure drugs can exacerbate ● diarrhea, and 4. Assess the patient’s
arterial vasodilator and causes renal impairment. ● loss of appetite medication history,
Route: relaxation of blood vessels ● Heart failure. Changes including any drug
IVTT which carry blood away from in hemodynamics allergies.
the heart and towards the caused by these drugs 5. Educate the patient and
Adverse Effects:
organs and tissues. The exact can exacerbate heart support person regarding
Frequency: mechanism of how hydralazine failure. CV: tachycardia, angina, the purpose of the
q 15-30 mins for causes arterial smooth muscle ● Hyponatremia and arrhythmias, edema, medication and the mode
systolic BP of 160 relaxation is not yet hypovolemia. Can be orthostatic hypotension of administration.
or greater than 160 understood. Hydrazine affects exacerbated by the GI: diarrhea, nausea, 6. Instruct the mother and
and for Diastolic BP calcium movement within blood therapeutic effects of vomiting support person regarding
of equal to or vessels. Calcium is required for the drug. Derm: rash the potential side effects
greater than110 muscle contraction and MS: arthralgias, arthritis and adverse effects of
mmhg therefore disturbances in Neuro: dizziness, the medication.
calcium movement may cause drowsiness, headache, 7. Monitor the patient for
smooth muscle relaxation in peripheral neuropathy adverse and allergic
the blood vessels. Hydralazine Misc: drug-induced lupus reactions to hydralazine.
is selective for arterioles (small syndrome Recognize and
arteries), and the overall effects immediately treat
of treatment include a respiratory distress and
decrease in arterial blood circulatory collapse,
pressure, and peripheral which are signs of a
vascular resistance. severe anaphylactic
reaction. Follow the
organization’s practice
for emergency response.
 8. Monitor the patient
during hydralazine
therapy until BP
stabilizes. Assess vital
signs frequently until BP
stabilizes at the desired
level.
9. Monitor the FHR pattern.
10. Institute “Risk to fall”
precautions based on the
organization’s practice.
11. Assess, treat, and
reassess pain.

References:
Robert, R. K. J., RPh, & Keith, H. (2020). Saunders Nursing Drug Handbook 2021, 1e (1st ed.). Saunders.
Elsevier – Clinical Skills │ Hydralazine. (2021, July 29). Elsevier. https://elsevier.health/en-US/preview/hydralazine

Antoniette Jane M. Pathay

Name of Student