DRUG STUDY

Date Generic Brand Classificatio Indication Mechanism Dosage & Time Adverse Nursing
Name Name n of Action Frequency Given Reaction Consideration
09-07- Dextrose dextros Glucose 50% Dextrose Hyperosmol  Do not use
21 50% e elevating Dextrose restores intravenous ar syndrome, unless the
Injection monohy agents Injection is blood injection of resulting solution is clear
drate indicated in glucose 10 to 25 from and seal is
the levels in grams of excessively intact. Discard
treatment of hypoglyce dextrose rapid unused portion.
insulin mia and (20 to 50 administratio Electrolyte
hypoglycem provides a mL of 50% n of deficits,
ia source of dextrose) concentrated particularly in
(hyperinsuli carbohydra dextrose serum
nemia or te calories may cause potassium and
insulin after IV mental phosphate, may
shock) to injection. It confusion occur during
restore decreases and/or loss prolonged use o
blood losses of of concentrated
glucose body consciousne dextrose
levels. The protein and ss. solutions.
solution is nitrogen, Reactions
also promotes which may  Blood electrolyte
indicated, glycogen occur monitoring is
after deposition, because of essential and
dilution, for and the solution fluid and
intravenous prevents or the electrolyte
infusion as ketosis. It technique of imbalances
a source of reverses administratio should be
carbohydrat CNS n include corrected.
e calories in effects of febrile Essential
patients hypoglyce response, vitamins and
whose oral mia by infection at minerals also
intake is rapidly the site of should be
restricted or increasing injection, provided as
inadequate serum venous needed.
to maintain glucose thrombosis
nutritional levels. or phlebitis  To minimize
requirement Dextrose extending hyperglycemia
s. Slow injection from the site and consequent
infusion of undergoes of injection, glycosuria, it is
hypertonic oxidation to extravasatio desirable to
solutions is carbon n and monitor blood
essential to dioxide and hypervolemi and urine
insure water. a. If an glucose and if
proper Water is an adverse necessary, add
utilization of essential reaction insulin. When a
dextrose constituent does occur, concentrated
and avoid of all body discontinue dextrose infusio
production tissues the infusion, is abruptly
of Average evaluate the withdrawn, it is
hyperglyce normal patient, advisable to
mia. adult institute follow with the
requiremen appropriate administration o
t ranges therapeutic 5% or 10%
from two to countermeas dextrose
three liters. ures and injection to avoid
Water save the rebound
balance is remainder of hypoglycemia.
maintained the fluid for
by various examination  Solutions
regulatory if deemed containing
mechanism necessary. dextrose should
s. Water be used with
distribution caution in
depends patients with
primarily on known
the subclinical or
concentrati overt diabetes
on of mellitus.
electrolytes
in the body  Care should be
compartme exercised to
nts. insure that the
needle is well
within the lumen
of the vein and
that
extravasation
does not occur.
If thrombosis
should occur
during
administration,
the injection
should be
stopped and
corrective
measures
instituted.

 Concentrated
dextrose
solutions should
not be
administered
subcutaneously
or
intramuscularly.