Veterinary Letters

ISSN 2581-2416
DOI: http://dx.doi.org/10.29244/avl.5.1.15-16
http://journal.ipb.ac.id/index.php/arshivetlett

Antimicrobial Sensitivity of Most Commonly Isolated Bacteria

from Feline Upper Respiratory Infection (URI)
Karen Lee Mei Fong1, Usamah Afiff 2, Safika 3
1
Undergraduate Students Faculty of Veterinary Medicine IPB University,
2
Division Teaching Staff of Infectious Diseases and Veterinary Public Health
3
Department of Infectious Diseases and Veterinary Public Health, Faculty of Veterinary Medicine IPB University
ABSTRAK: In cats, upper respiratory tract infection (URI) can be associated with primary or secondary bacterial infection and is genera

Kata kunci: antibiotics resistant, bacteria, cat, Upper Respiratory Tract Infection (URI)

antibiotik, lovebird, resistensi, Staphylococcus koagulase positif

INTRODUCTION
Respiratory infection are commonly found in cats Table 1 average diameter of inhibition zone and antimicrobial
presented to veterinary practices. Infection can occur in the sensitivity of most commonly isolated bacteria from Feline Upper
upper and lower respiratory tract. The isolated bacteria in feline Respiratory Tract Infection (URI) towards different antibiotics.
upper respiratory tract infections are Pasteurella, Streptococcus,
Staphylococcus, Bordetella and Escherichia coli.
The use of antibiotics in the treatment of bacterial
infections should be based on standards of clinical effectiveness,
low toxicity and the least possible impact on the multi-resistant
bacteria. balancing the need for successful therapy and
minimizing growth and dissemination of antimicrobial
resistance in animals and humans bacteria (Weese et al. 2015).

METODE
Materials used in this study were samples from the
nasal cavity of the cat with respiratory diease, medium
for isolation and identification of bacteria, and antibiotic
disc for amoxicillin, doxycycline, tetracycline,
azithromycin, ciprofloxacin, and cefotaxime. Antibiotic Key ; Amx (Amoxicillin), Azi (Azithromycin), Dox
sensitivity test were carried out using Kirby Bauer Agar (Doxycicline), Tet (Tetracycline), Ctx (Cefotaxime), Cip
Disc diffusion method. Interpretation data with Clinical (Ciprofloxacin) R (Resistance), I (Intermediate) S (Sesnitive)
Laboratory Standards Institute 2018 and few in Andrew
(2009), Arthur et al. (1996), Antibiotic Disc It can be seen from the table , four isolates of
Interpretative Criteria and Quality Control (2017), Direct Staphylococcus spp. were resistant to amoxicillin, and two
isolates were resistant to cefotaxime. Resistance to amoxicillin
RX (2015).
and tetracycline was discovered in one isolate of Streptococcus
spp., as well as resistance to cefotaxime in two isolates and two
RESULTS AND DISCUSSION isolates were intermediate to doxycycline. One Enterobacter spp
Staphylococcus spp, Streptococcus spp and Enterobacter spp isolate was resistant to amoxicillin and azithromycin, and two
are the most isolated bacteria from feline upper respiratory isolates were resistant to both.
infection (URI), hence only these three bacteria were used to
performed the antimicrobial test.
 Veterinary Letters
Amoxicillin resistance in Staphylococcus aureus may be in Beef Cattle. PLoS ONE.11(9):163-279
due to the expression of the femX gene, which results in Parnham MJ. Haber VE. Bourboulis EJG. Perletti G.
continuous repairing or abnormal thickening of cell walls, (Yao Verleden GM andVos R. 2014. Azihtromycin:
et al. 2019). Resistance in Streptococcus spp is primarily caused
mechanism of action and their relevance for clinical
by production of cytoplasmic proteins encoded by tet(M),
(Timothy, 2014). Resistance to cefotaxime is frequently caused
applications. Pharmacology & Therapeutics.
by the production of enzymes such as extended spectrum β- 143:225-245
lactamases (ESBLs), (Mir et al. 2016). Timothy J. Foster. 2017. Antibiotic resistance in
Third-generation cephalosporins are likely to induce Staphylococcus aureus. Current status and future
or select derepressed Enterobacter genetik variants of AmpC β- prospects. FEMS Microbiology Reviews.
lactamase, resulting in enzyme overproduction and resistance. 41(3):430–449
Resistance to azithromycin is due to changing the binding site or Weese JS. Giguère S. Guardabassi L. Morley PS. Papich
target through ribosome component mutation and increasing
efflux pump activity (Parnham et al. 2014).
M. Ricciuto DR. Sykes JE. 2015. ACVIM
Consensus Statement on Therapeutic Antimicrobial
Use in Animals and Antimicrobial Resistance.
CONCLUSION Journal of Veterinary internal medicine. 29(2):487-
This study provide information on the current
antimicrobial resistance in URI bacteria from cat in Bogor, 498
which may help to guide clinicians for the appropriate use of Yao Qian. Gao Linglin. Xu Teng. Chen Yun. Yang Xin.
antimicrobials Han Mengmeng. He Xiaotao. Li Chengheng. Zhou
Ruigang. Yang Yuhui. 2019. Amoxicillin
WRITER INFORMATION Administration Regimen and Resistance
Mechanisms of Staphylococcus aureus Established
Correspondence author :
in Tissue Cage Infection Model. Frontiers in
*UA: uafifff60@gmail.com Microbiology.10:1638
Divisi Mikrobiologi Medik, Departemen Ilmu Penyakit
Hewan dan Kesehatan Masyarakat Veteriner, Fakultas
Kedokteran Hewan, Institut Pertanian Bogor.
Jl. Agatis Kampus IPB Dramaga Bogor 16680.
**SFK: Fikakhan@yahoo.com
Divisi Mikrobiologi Medik, Departemen Ilmu Penyakit
Hewan dan Kesehatan Masyarakat Veteriner, Fakultas
Kedokteran Hewan, Institut Pertanian Bogor.
Jl. Agatis Kampus IPB Dramaga Bogor

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