Chlortetracycline

CHEMICAL NAME: 7-Chloro-4-Dimethylamino-1,4,4a,5,5a,6,11,12a-Octahydro-3,6,10,12,12a-Pentahydroxy-6-Meth-

yl-1,11-Dioxo-2-Naphthacenecarboxamide
WARNING STATEMENT REQUIRED: Where required, indicated in claims column or under section heading.
NOTE: Feed as Chlortetracycline calcium complex equivalent to chlortetracycline hydrochloride.

Chickens
1. FDA Status: No feed mill license required.
Regulation §558.128
WARNING: Varies by manufacturer. Refer to specific product label.
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Chickens Chlortetracycline 100-200 g/ton Control of infectious synovitis caused by
Mycoplasma synoviae susceptible to
Chlortetracycline.
LIMITATIONS FOR USE: Feed continuously for 7 to 14 days. For all Chlortetracycline products except
Aureomycin or Deracin: Do not feed to chickens producing eggs for human consumption.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Chlortetracycline 200-400 g/ton Control of chronic respiratory disease
(CRD) and air sac infection caused
by Mycoplasma gallisepticum
and Escherichia coli susceptible to
Chlortetracycline.
LIMITATIONS FOR USE: Feed continuously for 7 to 14 days. For all Chlortetracycline products except
Aureomycin or Deracin: Do not feed to chickens producing eggs for human consumption.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Chlortetracycline 500 g/ton Reduction of mortality due to
Escherichia coli infections susceptible
to Chlortetracycline
LIMITATIONS FOR USE: (1) Feed for 5 days. Zero-day withdrawal time when formulated from
Aureomycin Type A medicated articles or Type B medicated feeds under NADA 48-761 or Deracin Type A
medicated articles or Type B medicated feeds under ANADA 200-510.
(2) All other Chlortetracycline premixes: Feed for 5 days. Withdraw 24 hours prior to slaughter. Do not feed
to chickens producing eggs for human consumption.
___________________________________________________________________________________________________________________________

COMBINATIONS ALLOWED
2. FDA Status: Feed mill license required if the source of Clopidol contains more than 11.4 g/lb. (2.5%).
Regulation §558.175
LIMITATIONS FOR USE: Feed continuously as sole ration from time chicks are placed in floor pens for 7-14 days.
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Chickens (broilers Chlortetracycline 100-200 g/ton Aid in prevention of coccidiosis caused
and replacements) and by Eimeria tenella, Eimeria necatrix,
Clopidol 113.5 g/ton (0.0125%) Eimeria acervulina, Eimeria maxima,
Eimeria mivati and Eimeria brunetti in
broilers and replacement chickens
intended for use as caged layers and
for infectious synovitis caused by
Mycoplasma synoviae susceptible to
Chlortetracycline.
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3. FDA Status: No feed mill license required.
Regulation §558.195
WARNING STATEMENT REQUIRED: Do not feed to chickens producing eggs for human consumption.
CAUTION: Do not use in feeds containing bentonite.
LIMITATIONS FOR USE: Feed continuously for 7 to 14 days.
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Chickens Chlortetracycline 100-200 g/ton Control of infectious synovitis
and caused by Mycoplasma synoviae
susceptible to Chlortetracycline.
Decoquinate 27.2 g/ton For the prevention of coccidiosis caused
by Eimeria tenella, Eimeria necatrix,
Eimeria acervulina, Eimeria mivati,
Eimeria maxima and Eimeria brunetti.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Chlortetracycline 200-400 g/ton Control of chronic respiratory
and disease (CRD) and air sac
infection caused by Mycoplasma
gallisepticum and Escherichia
coli susceptible to Chlortetracycline.
Decoquinate 27.2 g/ton For the prevention of coccidiosis caused
by Eimeria tenella, Eimeria necatrix,
Eimeria acervulina, Eimeria mivati,
Eimeria maxima and Eimeria brunetti.
___________________________________________________________________________________________________________________________

4. FDA Status: No feed mill license required.

Regulation §558.355
WARNING: Do not feed to laying chickens. Do not feed to chickens over 16 weeks of age. Withdraw 24 hours before
slaughter.
CAUTION: Do not allow horses, mature turkeys or guinea fowl access to formulations containing Monensin. Inges-
tion of Monensin by horses and guinea fowl has been fatal. In the absence of coccidiosis, the
use of Monensin with no withdrawal period may limit feed intake resulting in reduced weight
gain.
LIMITATIONS FOR USE: Feed for 5 days as the sole ration. Not to be fed continuously for more than 5 days. FDA ap-
proval provides only for use of Chlortetracycline products manufactured by NADA sponsors No.
054771 (Zoetis) and No. 069254 (Pharmgate Animal Health).
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Chickens (broilers) Chlortetracycline 500 g/ton As an aid in the reduction of mortality
and due to Escherichia coli infections
susceptible to Chlortetracycline.
Monensin 90-110 g/ton As an aid in the prevention of
coccidiosis caused by Eimeria tenella,
Eimeria necatrix, Eimeria acervulina,
Eimeria mivati, Eimeria maxima and
Eimeria brunetti.
___________________________________________________________________________________________________________________________

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Chlortetracycline (Continued)
5. FDA Status: Feed mill license required if the source of Robenidine Hydrochloride contains more than 1.5 g/
lb. (0.33%).
Regulations §558.128 and §558.515
WARNING STATEMENT REQUIRED: Withdraw 5 days prior to slaughter. Do not feed to chickens producing eggs for
human consumption.
CAUTION STATEMENT REQUIRED: Do not use in feeds containing bentonite. Finished feeds (Type C) containing
Robenidine Hydrochloride must be fed within 50 days from date of manufacture.
LIMITATIONS FOR USE: FDA approval provides only for use of Chlortetracycline products manufactured by NADA
sponsor No. 054771 (Zoetis).
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Chickens (broilers Chlortetracycline 100-200 g/ton For control of infectious synovitis caused
or fryers) and by Mycoplasma synoviae susceptible to
Chlortetracycline.
Robenidine Hydrochloride 30 g/ton (0.0033%) As an aid in the prevention of
coccidiosis caused by Eimeria mivati,
Eimeria brunetti, Eimeria tenella,
Eimeria acervulina, Eimeria maxima and
Eimeria necatrix.
LIMITATIONS FOR USE: Feed continuously as sole ration for up to 14 days.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Chlortetracycline 200-400 g/ton For control of chronic respiratory disease
and (CRD) and air sac infection caused by
Mycoplasma gallisepticum and
Escherichia coli susceptible to
Chlortetracycline.
Robenidine Hydrochloride 30 g/ton (0.0033%) As an aid in the prevention of
coccidiosis caused by Eimeria mivati,
Eimeria brunetti, Eimeria acervulina,
Eimeria maxima, Eimeria tenella and
Eimeria necatrix.
LIMITATIONS FOR USE: Feed continuously as sole ration for up to 14 days.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Chlortetracycline 500 g/ton As an aid in the reduction of mortality
and due to Escherichia coli susceptible to
Chlortetracycline.
Robenidine Hydrochloride 30 g/ton (0.0033%) As an aid in the prevention of
coccidiosis caused by Eimeria mivati,
Eimeria brunetti, Eimeria acervulina,
Eimeria maxima, Eimeria tenella and
Eimeria necatrix.
LIMITATIONS FOR USE: Feed continuously as sole ration for up to 5 days.
__________________________________________________________________________________________________________________________

6. FDA Status: No feed mill license required.

Regulations §558.128 and §558.550
WARNING: Withdraw 24 hours before slaughter. Do not feed to laying chickens producing eggs for human consumption.
CAUTION: May be fatal if accidentally fed to adult turkeys or horses. Not approved for use with pellet binders.
LIMITATIONS FOR USE: In feeds containing 0.8% dietary calcium, not to be fed for more than 5 days. Must be thoroughly
mixed in feeds before use. FDA approval provides only for use of Chlortetracycline products manu-
factured by NADA sponsors No. 054771 (Zoetis) and No. 069254 (Pharmgate Animal Health).
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Chickens (broilers) Chlortetracycline 500 g/ton As an aid in the reduction of mortality
and due to Escherichia coli susceptible to
Chlortetracycline.
Salinomycin 40-60 g/ton For the prevention of coccidiosis caused
by Eimeria tenella, Eimeria necatrix,
Eimeria acervulina, Eimeria maxima,
Eimeria brunetti and Eimeria mivati.
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 Turkeys
7. FDA Status: No feed mill license required.
Regulation §558.128
WARNING: Do not feed to turkeys producing eggs for human consumption.
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Turkeys (growing) Chlortetracycline 200 g/ton Control of infectious synovitis caused by
Mycoplasma synoviae susceptible to
Chlortetracycline.
LIMITATIONS FOR USE: Feed continuously for 7 to 14 days.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Chlortetracycline 400 g/ton Control of hexamitiasis caused by
Hexamita meleagridis susceptible to
Chlortetracycline.
LIMITATIONS FOR USE: Feed continuously for 7 to 14 days.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Chlortetracycline 25 mg/lb. of Control of complicating bacterial
bodyweight organisms associated with bluecomb
(transmissible enteritis; coronaviral
enteritis) susceptible to Chlortetracycline.
LIMITATIONS FOR USE: Feed continuously for 7 to 14 days.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Turkeys Chlortetracycline 400 g/ton Reduction of mortality due to
(poults not over paratyphoid caused by Salmonella
4 weeks of age) typhimurium susceptible to
Chlortetracycline.
___________________________________________________________________________________________________________________________

Ducks
8. FDA Status: No feed mill license required.
Regulation §558.128
WARNING: Do not feed to ducks producing eggs for human consumption.
LIMITATIONS FOR USE: Feed not more than 21 days. Feed in complete ration to provide from 8 to 28 mg/lb. of bodyweight
per day depending upon age and severity of disease. FDA approval provides only for use of Chlortet-
racycline products manufactured under NADA 048-761 (Aureomycin) or ANADA 200-510 (Deracin).
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Ducks Chlortetracycline 200-400 g/ton For the control and treatment of fowl
cholera caused by Pasteurella multocida
susceptible to Chlortetracycline.
___________________________________________________________________________________________________________________________

Swine
9. FDA Status: No feed mill license required.
Regulation §558.128
WARNING: Withdrawal times vary by manufacturer. Read label for specific withdrawal time.
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Swine (growing) Chlortetracycline 50-100 g/ton Reducing the incidence of cervical
lymphadenitis (jowl abscesses) caused
by Group E Streptococci susceptible to
Chlortetracycline.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
(breeding) Chlortetracycline 400 g/ton Control of leptospirosis (reducing the
incidence of abortion and shedding of
Leptospirae) caused by Leptospira
pomona susceptible to Chlortetracycline.
LIMITATIONS FOR USE: Feed continuously for not more than 14 days.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

2021 Feed Additive Compendium | Additive Listings 167

Chlortetracycline (Continued)
Swine Chlortetracycline 10 mg/lb. bodyweight/day Treatment of bacterial enteritis caused
by Escherichia coli and Salmonella
choleraesuis and bacterial pneumonia
caused by Pasteurella multocida
susceptible to Chlortetracycline.
LIMITATIONS FOR USE: Feed for not more than 14 days. Feed approximately 400 g/ton,
varying with bodyweight and feed consumption to provide 10 mg/lb. of bodyweight per day. For products
manufactured under NADA 046-699 (ChlorMax), NADA 048-761 (Aureomycin), NADA 138-935 (Pennchlor)
or ANADA 200-510 (Deracin), zero-day withdrawal.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Swine Chlortetracycline 10 mg/lb. bodyweight/day For the control of porcine proliferative
enteropathies (ileitis) caused by Lawsonia
intracellularis susceptible to
Chlortetracycline.
LIMITATIONS FOR USE: Feed for not more than 14 days. Feed approximately 400 g/ton,
varying with bodyweight and feed consumption to provide 10 mg/lb. of bodyweight per day. FDA approval
provides only for use of products manufactured under NADA 048-761 (Aureomycin), 046-699 (ChlorMax) or
ANADA 200-510 (Deracin).
___________________________________________________________________________________________________________________________

COMBINATIONS ALLOWED
10. FDA Status: No feed mill license required.
Regulation §558.76
LIMITATIONS FOR USE: Feed for not more than 14 days. Feed approximately 400 g/ton Chlortetracycline, varying with
bodyweight and feed consumption to provide 10 mg/lb. of bodyweight per day. FDA approval
provides only for the use of Chlortetracycline products manufactured by NADA sponsors No.
054771 (Zoetis) and No. 069254 (Pharmgate Animal Health). The ileitis claim applies only to
Chlortetracycline products manufactured by NADA sponsor No. 054771 (Zoetis).
WARNING: Withdrawal times vary by manufacturer. Read label for specific withdrawal time.
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Swine Chlortetracycline 400 g/ton For treatment of bacterial enteritis
and (10 mg/lb. bodyweight/day) caused by Escherichia coli and
Salmonella choleraesuis and bacterial
pneumonia caused by Pasteurella
multocida susceptible to Chlortetracycline;
and for control of porcine proliferative
enteropathies (ileitis) caused by
Lawsonia intracellularis susceptible
to Chlortetracycline.
Bacitracin 10-30 g/ton For increased rate of weight gain and
Methylenedisalicylate improved feed efficiency.
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168 Additive Listings | 2021 Feed Additive Compendium

11. FDA Status: Feed mill license required if the source of Tiamulin contains more than 10 g/lb.
Regulations §558.128 and §558.600
WARNING: Withdraw 2 days before to slaughter.
CAUTION: Do not feed undiluted. Do not feed to animals other than swine. The effects of Tiamulin on swine reproduc-
tive performance, pregnancy and lactation have not been determined. Use as the only source
of Tiamulin and Chlortetracycline. Swine being treated with Tiamulin should not have access
to feeds containing polyether ionophores (e.g. Monensin, Lasalocid, Narasin, Salinomycin and
Semduramicin) as adverse reactions may occur. If signs of toxicity occur, discontinue use of
medicated feeds.
SPECIAL CONSIDERATIONS: Protect medicated feed from excessive temperatures. Do not store at warm tempera-
tures, 104°F (40°C), for more than 7 days.
LIMITATIONS FOR USE: Feed continuously as sole ration for 14 days. Feed approximately 400 g/ton Chlortetracycline,
varying with bodyweight and feed consumption to provide 10 mg/lb. of bodyweight per day.
FDA approval provides only for use of Chlortetracycline products manufactured under NADA
046-699 (ChlorMax), 048-761 (Aureomycin), 138-935 (Pennchlor) or ANADA 200-510 (Deracin).
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Swine Chlortetracycline 400 g/ton Treatment of bacterial enteritis caused by
and (10 mg/lb. bodyweight/day) Escherichia coli and Salmonella
choleraesuis and bacterial pneumonia
caused by Pasteurella multocida
susceptible to Chlortetracycline.
Tiamulin Hydrogen 35 g/ton For the control of swine dysentery
Fumerate associated with Brachyspira (formerly
Serpulina or Treponema) hyodysenteriae
susceptible to Tiamulin.
___________________________________________________________________________________________________________________________

Cattle
12. FDA Status: No feed mill license required except for free-choice feeds.
Regulation §558.128; For Residue Tolerances, See §556.150
WARNING STATEMENT REQUIRED: A withdrawal period has not been established for this product in pre-ruminating
calves. Do not use in calves to be processed for veal. This drug is not approved for use in
female dairy cattle 20 months of age or older, including dry dairy cows. Use in these cattle may
cause drug residues in milk and/or in calves born to these cows.
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Calves (up Chlortetracycline 10 mg/lb. bodyweight/day Treatment of bacterial enteritis
to 250 lb.) caused by Escherichia coli susceptible
to Chlortetracycline.
LIMITATIONS FOR USE: In milk replacers or starter feeds. A withdrawal period has not been established
for this product in preruminating calves. Do not use in calves to be processed for veal. Withdrawal times may
vary by manufacturer. Read label for specific withdrawal time.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Growing Cattle Chlortetracycline 70 mg/head/day Reduction of incidence of liver abscesses.
(over 400 lb.)
LIMITATIONS FOR USE: Withdrawal times may vary by manufacturer. Read label for specific
withdrawal time.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Beef cattle and Chlortetracycline 350 mg/head/day Control of bacterial pneumonia
dairy replacement associated with shipping fever complex
heifers caused by Pasteurella spp. susceptible
to Chlortetracycline.
WARNING: Withdrawal times vary by manufacturer. Read label for specific withdrawal times.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Beef Cattle (under Chlortetracycline 350 mg/head/day Control of active infection of
700 lb.) anaplasmosis caused by Anaplasma
marginale susceptible to
Chlortetracycline.
WARNING: Withdrawal times vary by manufacturer. Read label for specific withdrawal times.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

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Chlortetracycline (Continued)
Beef Cattle Chlortetracycline 0.5 mg/lb. of bodyweight/day Control of active infection of
(over 700 lb.) anaplasmosis caused by Anaplasma
marginale susceptible to
Chlortetracycline.
WARNING: Withdrawal times vary by manufacturer. Read label for specific withdrawal times.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Calves, beef and Chlortetracycline 10.0 mg/lb. bodyweight/day Treatment of bacterial enteritis caused
non-lactating dairy by Escherichia coli and bacterial
cattle pneumonia caused by Pasteurella
multocida organisms susceptible to
Chlortetracycline.
WARNING: Withdrawal times vary by manufacturer. Read label for specific withdrawal times.
LIMITATIONS FOR USE: Feed for not more than 5 days. Feed approximately 400 g/ton varying with
bodyweight and feed consumption to provide 10 mg/lb. per day.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Beef and non-lactating Chlortetracycline 0.5-2.0 mg/lb. bodyweight/day As an aid in the control of active infection
dairy cattle of anaplasmosis caused by Anaplasma
marginale susceptible to Chlortetracycline.
LIMITATIONS: In free-choice cattle feeds such as feed blocks or salt-mineral mixes; Free choice feed must
be manufactured from NADA 048-761 (Aureomycin) or ANADA 200-510 (Deracin) using an FDA-approved
formulation. Feed mill license not required if following free-choice loose-mineral formulation published in
21 CFR 558.128.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Calves, beef and Chlortetracycline 500-4,000 g/ton Treatment of bacterial enteritis caused by
non-lactating dairy Escherichia coli and bacterial pneumonia
cattle caused by Pasteurella multocida
organisms susceptible to Chlortetracycline.
WARNING: Withdrawal times vary by manufacturer. Read label for specific withdrawal times.
LIMITATIONS: Feed continuously for not more than 5 days to provide 10 mg/lb. bodyweight per
day; must be manufactured under NADA 048-761 (Aureomycin) or ANADA 200-510 (Deracin).
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Beef and Chlortetracycline 6,000 g/ton As an aid in the control of active infection
non-lactating dairy of anaplasmosis caused by Anaplasma
cattle marginale susceptible to Chlortetracycline.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Calves, beef and Chlortetracycline 4,000-20,000 g/ton Treatment of bacterial enteritis caused by
non-lactating dairy Escherichia coli and bacterial pneumonia
cattle caused by Pasteurella multocida
organisms susceptible to Chlortetracycline.
LIMITATIONS: As a top dress, varying with bodyweight and feed consumption, to provide 10 mg/lb.
bodyweight per day. Treat for not more than 5 days, must be manufactured from Aureomycin Type A
medicated articles manufactured under NADA 048-761 or Deracin Type A medicated articles manufactured
under ANADA 200-510.
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COMBINATION ALLOWED
13. FDA Status: No feed mill license required.
Regulation §558.195
WARNING STATEMENT REQUIRED: Do not feed to animals producing milk for food. A withdrawal period has not been
established for this product in pre-ruminating calves. Do not feed to calves to be processed for
veal. Withdraw 24 hours prior to slaughter when manufactured from ChlorMax Type A medicated
articles and Pennchlor Type A medicated articles. Zero withdrawal time when manufactured
from Aureomycin Type A medicated articles manufactured by NADA sponsor No. 054771 (Zoetis)
and Deracin Type A medicated articles manufactured by ANADA sponsor No. 069254 (Pharmgate
Animal Health).
CAUTION: Do not use Decoquinate in feeds containing bentonite.
LIMITATIONS FOR USE: Feed Type C feed at a rate to provide 22.7 mg Decoquinate and 1 g Chlortetracycline per 100
lb. of bodyweight (0.5 mg/kg) per day for not more than 5 days. When consumed, feed 22.7 mg
Decoquinate per 100 lb. bodyweight per day for total of 28 days to prevent coccidiosis. Type C
feed may be prepared from dry or liquid Type B feed containing 0.0125-0.5% Decoquinate. Type
C cattle feeds may be manufactured from Decoquinate liquid Type B feeds having a pH be-
tween 5.0 and 6.5 and containing a suspending agent to maintain a viscosity of not less than
500 centipoises.
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Calves, beef Chlortetracycline 500-4,000 g/ton For prevention of coccidiosis caused by
and nonlactating and Eimeria bovis and Eimeria zuernii.
dairy cattle Decoquinate 12.9-90.8 g/ton For treatment of bacterial enteritis caused
by Escherichia coli and for treatment of
bacterial pneumonia caused by Pasteurella
multocida organisms susceptible to
Chlortetracycline.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Chlortetracycline 4,000-20,000 g/ton For prevention of coccidiosis caused by
and Eimeria bovis and Eimeria zuernii.
Decoquinate 90.9-535.7 g/ton For treatment of bacterial enteritis caused
by Escherichia coli and for treatment of
bacterial pneumonia caused by Pasteurella
multocida organisms susceptible to
Chlortetracycline.
LIMITATIONS FOR USE: Feed Type C medicated feed supplements as a top dress or mix into daily ration
to provide 22.7 mg Decoquinate and 1 g Chlortetracycline per 100 lb. bodyweight per day for not more than
5 days.
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Chlortetracycline (Continued)
14. FDA Status: No feed mill license required.
Regulation 558.305
CAUTION STATEMENT REQUIRED: Labeling for all Type B feeds (liquid and dry) and Type C feeds containing Laid-
lomycin shall bear the following statements: Do not allow horses or other equines access to
feeds containing Laidlomycin Propionate Potassium. The safety of Laidlomycin Propionate
Potassium in unapproved species has not been established. Not for use in animals intended for
breeding. Feed only to cattle being fed in confinement for slaughter.
WARNING STATEMENT REQUIRED: A withdrawal period has not been established for this product in pre-ruminating
calves. Do not use in calves to be processed for veal.
SPECIAL CONSIDERATIONS: Laidlomycin liquid Type B feeds may be manufactured from dry Laidlomycin Type A
articles. Liquid Type B feeds must have a pH of 6.0 to 8.0, dry matter of 62 to 75%, and bear the
appropriate mixing directions as follows:
(1) For liquid Type B feeds stored in recirculating tank systems:
Recirculate immediately prior to use for no less than 10 minutes, moving not less than
1% of the tank contents per minute from bottom of tank to the top. Recirculate daily as
described even when not used.
(2) For liquid Type B feeds stored in mechanical, air or other agitation type tank
systems: Agitate immediately prior to use for not less than 10 minutes, creating a
turbulence at the bottom of the tank that is visible at the top. Agitate daily as described
even when not used.
The expiration date for the liquid Type B feed is 21 days after date of manufacture. The expira-
tion date for the dry Type C feed made from the liquid Type B feed is 7 days after the date of
manufacture.
LIMITATIONS FOR USE: FDA approval provides only for the use of Chlortetracycline products manufactured by NADA
sponsor No. 054771 (Zoetis).
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Beef cattle Chlortetracycline 10 mg/lb. bodyweight For treatment of bacterial enteritis caused
(confined) and by Escherichia coli and bacterial
pneumonia caused by Pasteurella
multocida organisms susceptible to
Chlortetracycline.
Laidlomycin 5 g/ton For improved feed efficiency and
increased rate of weight gain.
LIMITATIONS FOR USE: Feed continuously at a rate of 30 to 75 mg Laidlomycin Propionate Potassium
per head per day for not more than 5 days.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Chlortetracycline 350 mg/head/day For control of bacterial pneumonia
and associated with shipping fever complex
caused by Pasteurella spp. susceptible to
Chlortetracycline.
Laidlomycin 5 g/ton For improved feed efficiency and
increased rate of weight gain.
LIMITATIONS FOR USE: Feed continuously at a rate of 30 to 75 mg Laidlomycin Propionate Potassium
per head per day.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Chlortetracycline 10 mg/lb. bodyweight For treatment of bacterial enteritis caused
and by Escherichia coli and bacterial
pneumonia caused by Pasteurella
multocida organisms susceptible to
Chlortetracycline.
Laidlomycin 5-10 g/ton For improved feed efficiency.
LIMITATIONS FOR USE: Feed continuously at a rate of 30 to 150 mg Laidlomycin Propionate Potassium
per head per day for not more than 5 days.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Chlortetracycline 350 mg/head/day For control of bacterial pneumonia
and associated with shipping fever complex
caused by Pasteurella spp. susceptible to
Chlortetracycline.
Laidlomycin 5-10 g/ton For improved feed efficiency.
LIMITATIONS FOR USE: Feed continuously at a rate of 30-150 mg Laidlomycin Propionate Potassium
per head per day.
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15. FDA Status: No feed mill license required.
Regulations §558.128 and §558.311
WARNING STATEMENT REQUIRED: A withdrawal period has not been established for this product in pre-ruminating
calves. Do not use in calves to be processed for veal.
CAUTION STATEMENT REQUIRED: The safety of Lasalocid for use in unapproved species has not been established.
For Type B feeds: Feeding undiluted or mixing errors may result in an excess Lasalocid concen-
tration which could be fatal to cattle. Do not allow horses or other equines access to Type B
feeds containing Lasalocid as ingestion may be fatal. For Type C feeds: Do not allow horses or
other equines access to feeds containing Lasalocid.
LIMITATIONS FOR USE: FDA approval provides only for the use of Chlortetracycline products manufactured by NADA
sponsor No. 054771 (Zoetis) and Deracin Type A medicated articles manufactured by ANADA
sponsor No. 069254 (Pharmgate Animal Health).
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Cattle (fed Chlortetracycline 25-100 g/ton For control of bacterial pneumonia
in confinement and associated with shipping fever complex
for slaughter) caused by Pasteurella spp. susceptible to
Chlortetracycline.
Lasalocid 10-30 g/ton For improved feed efficiency.
LIMITATIONS FOR USE: Feed continuously in complete feed at a rate of 350 mg Chlortetracycline and
not less than 100 mg nor more than 360 mg of Lasalocid Sodium activity per head per day.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Cattle (under 700 lb. Chlortetracycline 25-100 g/ton For control of active infection of
fed in confinement and anaplasmosis caused by Anaplasma
for slaughter) marginale susceptible to Chlortetracycline.
Lasalocid 10-30 g/ton For improved feed efficiency.
LIMITATIONS FOR USE: Feed continuously in complete feed at a rate of 350 mg Chlortetracycline and
not less than 100 mg nor more than 360 mg of Lasalocid Sodium activity per head per day.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Cattle (fed in Chlortetracycline 500-2,000 g/ton For treatment of bacterial enteritis caused
confinement and by Escherichia coli and bacterial
for slaughter) pneumonia caused by Pasteurella
multocida organisms susceptible to
Chlortetracycline.
Lasalocid 10-30 g/ton For improved feed efficiency.
LIMITATIONS FOR USE: Feed continuously in complete feed for not more than 5 days to provide 10 mg
Chlortetracycline per pound of bodyweight per day and not less than 100 mg nor more than 360 mg of
Lasalocid Sodium activity per head per day.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Cattle (fed in Chlortetracycline 25-42.2 g/ton For control of bacterial pneumonia
confinement and associated with shipping fever complex
for slaughter) caused by Pasteurella spp. susceptible to
Chlortetracycline.
Lasalocid 25-30 g/ton For increased rate of weight gain and
improved feed efficiency.
LIMITATIONS FOR USE: Feed continuously in complete feed at a rate of 350 mg Chlortetracycline and not
less than 250 mg nor more than 360 mg of Lasalocid Sodium activity per head per day.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Cattle (under 700 lb. Chlortetracycline 25-42.2 g/ton For control of active infection of
fed in confinement and anaplasmosis caused by Anaplasma
for slaughter) marginale susceptible to Chlortetracycline.
Lasalocid 25-30 g/ton For increased rate of weight gain and
improved feed efficiency.
LIMITATIONS FOR USE: Feed continuously in complete feed at a rate of 350 mg Chlortetracycline
and not less than 250 mg nor more than 360 mg of Lasalocid Sodium activity per head per day.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Cattle (fed in Chlortetracycline 500-1,200 g/ton For treatment of bacterial enteritis caused
confinement and by Escherichia coli and bacterial pneumonia
for slaughter) caused by Pasteurella multocida organisms
susceptible to Chlortetracycline.
Lasalocid 25-30 g/ton For increased rate of weight gain and
improved feed efficiency.
LIMITATIONS FOR USE: Feed continuously in complete feed for not more than 5 days to provide 10 mg
Chlortetracycline per pound of bodyweight per head per day and not less than 250 mg nor more than 360 mg
of Lasalocid Sodium activity per head per day.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

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Chlortetracycline (Continued)
Beef Cattle Chlortetracycline 25-2,800 g/ton For control of active infection of
(under 700 lb.) and anaplasmosis caused by Anaplasma
marginale susceptible to Chlortetracycline.
Lasalocid 30-181.8 g/ton For control of coccidiosis caused by
Eimeria bovis and Eimeria zuernii.
LIMITATIONS FOR USE: Hand feed continuously at a rate of 350 mg Chlortetracycline per head per day
and 1 mg Lasalocid per 2.2 lb. bodyweight with a maximum of 360 mg Lasalocid per head per day.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Beef Cattle Chlortetracycline 25-2,800 g/ton For control of bacterial pneumonia
(up to 800 lb.) and associated with shipping fever complex
caused by Pasteurella spp. susceptible to
Chlortetracycline.
Lasalocid 30-181.8 g/ton For control of coccidiosis caused by
Eimeria bovis and Eimeria zuernii.
LIMITATIONS FOR USE: Hand feed continuously at a rate of 350 mg Chlortetracycline per head per day
and 1 mg Lasalocid per 2.2 lb. bodyweight per day with a maximum of 360 mg Lasalocid per head per day.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Cattle Chlortetracycline 500-4,000 g/ton For treatment of bacterial enteritis caused
(up to 800 lb.) and by Escherichia coli and bacterial pneumonia
caused by Pasteurella multocida organisms
susceptible to Chlortetracycline.
Lasalocid 30-181.8 g/ton For control of coccidiosis caused by
Eimeria bovis and Eimeria zuernii.
LIMITATIONS FOR USE: Hand feed continuously for not more than 5 days to provide 10 mg
Chlortetracycline per pound bodyweight per day and 1 mg Lasalocid per 2.2 lb. bodyweight per day with a
maximum of 360 mg Lasalocid per head per day.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Pasture Cattle Chlortetracycline 25-700 g/ton For control of bacterial pneumonia
slaughter, stocker, and associated with shipping fever complex
feeder cattle, caused by Pasteurella spp. susceptible to
beef replacement Chlortetracycline.
heifers) Lasalocid 30-600 g/ton For increased rate of weight gain.
LIMITATIONS FOR USE: Hand feed continuously at a rate of 350 mg Chlortetracycline and not less than
60 mg nor more than 300 mg Lasalocid per head daily in at least 1 lb. of feed. Intakes of Lasalocid in excess of
200 mg/head/day have not been shown to be more effective than 200 mg/head/day.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Pasture Cattle Chlortetracycline 25-700 g/ton For control of active infection of
(under 700 lb., and anaplasmosis caused by Anaplasma
slaughter, stocker, marginale susceptible to Chlortetracycline.
feeder cattle, beef Lasalocid 30-600 g/ton For increased rate of weight gain.
replacement heifers) LIMITATIONS FOR USE: Hand feed continuously at a rate of 350 mg Chlortetracycline and not less than
60 mg nor more than 300 mg Lasalocid per head daily in at least 1 lb. of feed. Intakes of Lasalocid in excess of
200 mg per head per day have not been shown to be more effective than 200 mg per head per day.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Pasture Cattle Chlortetracycline 25-1,100 g/ton For control of active infection of
(over 700 lb., and anaplasmosis caused by Anaplasma
slaughter, stocker, marginale susceptible to Chlortetracycline.
feeder cattle, beef Lasalocid 30-600 g/ton For increased rate of weight gain.
replacement heifers) LIMITATIONS FOR USE: Hand feed continuously at a rate of 0.5 mg Chlortetracycline per pound bodyweight
per day and not less than 60 mg nor more than 300 mg Lasalocid per head daily in at least 1 lb. of feed. Intakes
in excess of 200 mg per head per day have not been shown to be more effective than 200 mg per head per day.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Pasture Cattle Chlortetracycline 500-4,000 g/ton For treatment of bacterial enteritis caused
(slaughter, stocker, and by Escherichia coli and bacterial
feeder cattle, dairy pneumonia caused by Pasteurella
and beef replacement multocida organisms susceptible to
heifers) Chlortetracycline.
Lasalocid 30-600 g/ton For increased rate of weight gain.
LIMITATIONS FOR USE: Hand feed continuously for not more than 5 days to provide 10 mg
Chlortetracycline per pound bodyweight per day and not less than 60 mg nor more than 300 mg Lasalocid per
head daily in at least 1 lb. of feed. Intakes of Lasalocid in excess of 200 mg per head per day have not been
shown to be more effective than 200 mg per head per day.
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174 Additive Listings | 2021 Feed Additive Compendium

 Sheep
16. FDA Status: No feed mill license required.
Regulation §558.128
LIMITATIONS FOR USE: FDA approval provides only for use of Chlortetracycline products manufactured under NADA
048-761 (Aureomycin), NADA 138-935 (Pennchlor) or ANADA 200-510 (Deracin).
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Sheep (breeding) Chlortetracycline 80 mg/head/day Reducing the incidence of (vibrionic)
abortion caused by Campylobacter fetus
infection susceptible to Chlortetracycline.
___________________________________________________________________________________________________________________________

Psittacine Birds
17. FDA Status: No feed mill license required.
Regulation §558.128
WARNING: Psittacosis, avian chlamydiosis or ornithosis is a reportable communicable disease, transmissible be-
tween wild and domestic birds, other animals and man. Contact appropriate public health and
regulatory officials.
LIMITATIONS FOR USE: Feed continuously for 45 days; each bird should consume daily an amount of medicated feed
equal to one fifth of its bodyweight. FDA approval provides only for use of Chlortetracycline
products manufactured under NADA 048-761 (Aureomycin) or ANADA 200-510 (Deracin).
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Psittacine birds Chlortetracycline 10 mg/g of finished feed daily Treatment of psittacine birds suspected
(cockatoos, macaws, or known to be infected with
parrots) psittacosis caused by Chlamydia
psittaci sensitive to Chlortetracycline.
___________________________________________________________________________________________________________________________

PRODUCT INFORMATION
Chlortetracycline
Trade Name: AUREOMYCIN Granular Chlortetracycline Type A Medicated Articles and ChlorMax 50, Zoetis Inc., Kalamazoo, Mich.
49007; Concentrations and Packaging: AUREOMYCIN 50 Granular, AUREOMYCIN 90 Granular, AUREOMYCIN 90 Meal and
AUREOMYCIN 100 Granular Chlortetracycline calcium complex equivalent to 50, 90 and 100 g Chlortetracycline HCl per pound in
50-lb. multi-wall bags; ChlorMax 50 - 50 g Chlortetracycline per pound on a grain carrier in 50-lb. multi-wall bags; Expiration Date:
See package label.

Trade Name: CLTC 100-MR Type A Medicated Article, Phibro Animal Health, Glenpointe Centre East, 3rd Floor, 300 Frank W. Burr
Blvd., Suite 21, Teaneck, N.J. 07666; Concentration: CLTC 100-MR 100 g Chlortetracycline HCl per pound on a dextrose monohydrate
carrier for milk replacers in a 50-lb. drum; Expiration Date: See package label.

Trade Name: Deracin 100 Meal, Pennchlor 100 Hi-Flo, Pennchlor 100G, Deracin 90 Meal, Pennchlor 90G, Deracin 50 Meal, Pennchlor
50, Pennchlor 50G Type A Medicated Articles, Pharmgate Animal Health LLC, 14040 Industrial Rd., Omaha, Neb. 68144; Concentra-
tions: Deracin 100 Meal, Pennchlor 100 Hi-Flo, Pennchlor 100G, Deracin 90 Meal, Pennchlor 90G, Deracin 50 Meal, Pennchlor 50 and
Pennchlor 50G contain Chlortetracycline as calcium complex equivalent to 100, 90 and 50 g Chlortetracycline HCl per pound; Expira-
tion Date: See package label.
___________________________________________________________________________________________________________________________

2021 Feed Additive Compendium | Additive Listings 175