Lincomycin

CHEMICAL NAME: Lincomycin

Chickens
1. FDA Status: No feed mill license required.
Regulation §558.325
CAUTION STATEMENT REQUIRED: Do not allow rabbits, hamsters, guinea pigs, horses or ruminants access to feeds
containing Lincomycin. Ingestion by these species may result in severe gastrointestinal effects.
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Chickens (broilers) Lincomycin 2 g/ton For control of necrotic enteritis
caused by Clostridium spp., or other
organisms susceptible to Lincomycin.
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COMBINATIONS ALLOWED
2. FDA Status: No feed mill license required.
Regulation §558.325
WARNING STATEMENT REQUIRED: Do not feed to laying hens producing eggs for human consumption.
CAUTION STATEMENT REQUIRED: Not for use in laying hens, breeding chickens or turkeys. Do not allow rabbits,
hamsters, guinea pigs, horses or ruminants access to feeds containing Lincomycin. Ingestion
by these species may result in severe gastrointestinal effects.
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Chickens (broilers) Lincomycin 2 g/ton For control of necrotic enteritis caused
and or complicated by Clostridium spp., or
other organisms susceptible to Lincomycin.
Decoquinate 27.2 g/ton For the prevention of coccidiosis caused
by Eimeria tenella, Eimeria necatrix,
Eimeria acervulina, Eimeria maxima,
Eimeria mivati and Eimeria brunetti.
LIMITATIONS: Feed as sole ration to broiler chickens. Do not use in feeds containing bentonite.
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3. FDA Status: No feed mill license required.

Regulation §558.325
WARNING STATEMENT REQUIRED: Withdraw 5 days before slaughter. Do not feed to laying hens producing eggs for
human consumption.
CAUTION STATEMENT REQUIRED: Not for use in laying hens, breeding chickens or turkeys. Do not allow rabbits,
hamsters, guinea pigs, horses or ruminants access to feeds containing Lincomycin. Ingestion
by these species may result in severe gastrointestinal effects.
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Chickens (broilers) Lincomycin 2 g/ton For control of necrotic enteritis caused
and or complicated by Clostridium spp., or
other organisms susceptible to Lincomycin.
Lasalocid 8-113 g/ton For the prevention of coccidiosis
caused by Eimeria tenella, Eimeria necatrix,
Eimeria acervulina, Eimeria brunetti,
Eimeria mivati and Eimeria maxima.
LIMITATIONS: Feed as sole ration to broiler chickens.
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214 Additive Listings | 2021 Feed Additive Compendium

4. FDA Status: No feed mill license required.
Regulation §558.325
WARNING STATEMENT REQUIRED: Do not feed to laying hens producing eggs for human consumption. Do not feed
to chickens over 16 weeks of age.
CAUTION STATEMENT REQUIRED: Not for use in laying hens, breeding chickens or turkeys. Not for replacement
chickens intended to become broiler breeder chickens. Do not allow horses, other equines, ma-
ture turkeys or guinea fowl access to feed containing Monensin. Do not allow rabbits, hamsters,
guinea pigs, horses or ruminants access to feeds containing Lincomycin. Ingestion by these
species may result in severe gastrointestinal effects.
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Chickens (broilers) Lincomycin 2 g/ton For control of necrotic enteritis caused or
and complicated by Clostridium spp., or other
organisms susceptible to Lincomycin.
Monensin 90-110 g/ton As an aid in the prevention of coccidiosis
caused by Eimeria necatrix, Eimeria
acervulina, Eimeria brunetti, Eimeria
mivati and Eimeria maxima.
LIMITATIONS: Feed as sole ration to broiler chickens.
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5. FDA Status: No feed mill license required.

Regulation §558.325
WARNING STATEMENT REQUIRED: Withdraw 5 days before slaughter. Do not feed to laying hens producing eggs for
human consumption.
CAUTION STATEMENT REQUIRED: Not for use in laying hens, breeding chickens or turkeys. Do not allow rabbits,
hamsters, guinea pigs, horses or ruminants access to feeds containing Lincomycin. Ingestion
by these species may result in severe gastrointestinal effects.
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Chickens (broilers) Lincomycin 2 g/ton For control of necrotic enteritis caused
and or complicated by Clostridium spp., or
other organisms susceptible to Lincomycin.
Robenidine Hydrochloride 30 g/ton As an aid in the prevention of coccidiosis
caused by Eimeria mivati, Eimeria brunetti,
Eimeria tenella, Eimeria acervulina,
Eimeria maxima and Eimeria necatrix.
LIMITATIONS: Feed as sole ration to broiler chickens. Type C feed containing Robenidine Hydrochloride
must be feed within 50 days from date of manufacture. Do not use in feeds containing bentonite.
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6. FDA Status: No feed mill license required.

Regulation §558.325
WARNING STATEMENT REQUIRED: Do not feed to laying hens producing eggs for human consumption.
CAUTION STATEMENT REQUIRED: Not for use in laying hens, breeding chickens or turkeys. May be fatal if accidently
fed to adult turkeys or to horses. Do not allow rabbits, hamsters, guinea pigs, horses or rumi-
nants access to feeds containing Lincomycin. Ingestion by these species may result in severe
gastrointestinal effects.
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Chickens (broilers) Lincomycin 2 g/ton For control of necrotic enteritis caused or
and complicated by Clostridium spp., or other
organisms susceptible to Lincomycin.
Salinomycin 40-60 g/ton For prevention of coccidiosis caused by
Eimeria tenella, Eimeria necatrix, Eimeria
acervulina, Eimeria maxima, Eimeria
brunetti and Eimeria mivati.
LIMITATIONS: Feed as sole ration to broiler chickens.
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2021 Feed Additive Compendium | Additive Listings 215

Lincomycin (Continued)
7. FDA Status: No feed mill license required.
Regulation §558.325
WARNING STATEMENT REQUIRED: Not for use in laying hens, breeder chickens or turkeys.
CAUTION STATEMENT REQUIRED: Not for use in laying hens, breeder chickens or turkeys. Do not allow rabbits,
hamsters, guinea pigs, horses or ruminants access to feeds containing Lincomycin. Ingestion
by these species may result in severe gastrointestinal effects.
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Chickens (broilers) Lincomycin 2 g/ton For control of necrotic enteritis caused or
and complicated by Clostridium spp., or other
organisms susceptible to Lincomycin.
Zoalene 113.5 g/ton For the prevention and control of
coccidosis.
LIMITATIONS: Feed as the sole ration from the time chicks are placed in floor pens until slaughtered for meat.
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Swine
8. FDA Status: No feed mill license required.
Regulation §558.325
CAUTION STATEMENT REQUIRED: Occasionally, swine fed Lincomycin may, within the first 2 days after the onset of
treatment, develop diarrhea and/or swelling of the anus. On rare occasions, some pigs may
show reddening of the skin and irritable behavior. These conditions have been self-correcting
within 5-8 days without discontinuing the Lincomycin treatment. The effects of Lincomycin on
swine reproductive performance, pregnancy and lactation have not been determined. Not for
use in swine intended for breeding when Lincomycin is fed at 20 g/ton of complete feed. Do not
allow rabbits, hamsters, guinea pigs, horses or ruminants access to feeds containing Lincomy-
cin. Ingestion by these species may result in severe gastrointestinal effects.
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Swine Lincomycin 40 g/ton For control of swine dysentery and the
control of porcine proliferative enteropathy
(ileitis) caused by Lawsonia intracellularis.
LIMITATIONS FOR USE: For use in animals or on premises with a history of swine dysentery, but where
symptoms have not yet occurred. Feed as the sole ration.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Lincomycin 100 g/ton followed by 40 g/ton For treatment and control of swine
dysentery and the control of porcine
proliferative enteropathy (ileitis) caused
by Lawsonia intracellularis.
LIMITATIONS FOR USE: Feed 100 g/ton of complete feed as the sole ration for 3 weeks or until signs of
disease (watery, mucoid or bloody stools) disappear, followed by 40 g of Lincomycin per ton.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Lincomycin 100 g/ton For treatment of swine dysentery and the
control of porcine proliferative
enteropathy (ileitis) caused by Lawsonia
intracellularis.
LIMITATIONS FOR USE: Feed as sole ration for 3 weeks or until signs of disease (watery, mucoid or
bloody stools) disappear.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Lincomycin 100-200 g/ton For reduction in the severity of the effects
of respiratory disease associated with
Mycoplasma hyopneumoniae.
LIMITATIONS FOR USE: Feed as sole ration for 21 days.
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216 Additive Listings | 2021 Feed Additive Compendium

COMBINATIONS ALLOWED
9. FDA Status: Feed mill license required if the source of Fenbendazole contains more than 8.87 g/lb. (1.96%).
Regulations §558.325, §558.258 and §556.275 (tolerance)
CAUTION STATEMENT REQUIRED: Occasionally, swine fed Lincomycin may, within the first 2 days after the onset of
treatment, develop diarrhea and/or swelling of the anus. On rare occasions, some pigs may
show reddening of the skin and irritable behavior. These conditions have been self-correcting
within 5-8 days without discontinuing the Lincomycin treatment. The effects of Lincomycin on
swine reproductive performance, pregnancy and lactation have not been determined. Not for
use in swine intended for breeding when Lincomycin is fed at 20 g/ton of complete feed. Do not
allow rabbits, hamsters, guinea pigs, horses or ruminants access to feeds containing Lincomy-
cin. Ingestion by these species may result in severe gastrointestinal effects.
LIMITATIONS FOR USE: Feed as sole ration in complete feed for a period of from 3-12 days so to provide a total intake
of 9 mg/kg of bodyweight of Fenbendazole. No withdrawal time needed.
NOTE: Consult veterinarian for assistance in the diagnosis, treatment and control of parasitism.
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Swine Lincomycin 40 g/ton For control of swine dysentery and the
and control of porcine proliferative
enteropathy (ileitis) caused by Lawsonia
intracellularis. Feed as the sole ration. For
use in animals or on premises with a
history of swine dysentery, but where
symptoms have not yet occurred.
Fenbendazole 10-80 g/ton (A total of 9 mg/kg of For the removal of: Lungworms:
bodyweight divided over a Metastrongylus apri, Metastrongylus
period of 3-12 days) pudendotectus. Gastrointestinal worms:
Adult and larvae (L3, L4 stages, liver,
lung, intestinal forms) large roundworm
(Ascaris suum); nodular
(Oesophagostomum dentatum,
Ornithostrongylus quadrispinulatum);
small stomach (Hyostrongylus rubidus);
Adult and larvae (L2, L3, L4 stages
intestinal mucosal forms) whipworm
(Trichuris suis); Kidneyworm: Adult and
larvae Stephanurus dentatus.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Lincomycin 100 g/ton For treatment of swine dysentery and the
and control of porcine proliferative enteropathy
(ileitis) caused by Lawsonia intracellularis.
Feed as sole ration for three weeks or until
signs of disease (watery, mucoid or
bloody stools) disappear.
Fenbendazole 10-80 g/ton (A total of 9 mg/kg For the removal of: Lungworms:
of bodyweight divided over a Metastrongylus apri, Metastrongylus
period of 3-12 days) pudendotectus. Gastrointestinal worms:
Adult and larvae (L3, L4 stages, liver,
lung, intestinal forms) large roundworm
(Ascaris suum); nodular
(Oesophagostomum dentatum,
Ornithostrongylus quadrispinulatum);
small stomach (Hyostrongylus rubidus);
Adult and larvae (L2, L3, L4 stages
intestinal mucosal forms) whipworm
(Trichuris suis); Kidneyworm: Adult and
larvae Stephanurus dentatus.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

2021 Feed Additive Compendium | Additive Listings 217

Lincomycin (Continued)
Lincomycin 200 g/ton For reduction in the severity of swine
and mycoplasmal pneumonia caused by
Mycoplasma hyopneumoniae. Feed as
sole ration for 21 days.
Fenbendazole 10-80 g/ton (A total of 9 mg/kg For the removal of: Lungworms:
of bodyweight divided over a Metastrongylus apri, Metastrongylus
period of 3-12 days) pudendotectus. Gastrointestinal worms:
Adult and larvae (L3, L4 stages, liver,
lung, intestinal forms) large roundworm
(Ascaris suum); nodular
(Oesophagostomum dentatum,
Ornithostrongylus quadrispinulatum);
small stomach (Hyostrongylus rubidus);
Adult and larvae (L2, L3, L4 stages
intestinal mucosal forms) whipworm
(Trichuris suis); Kidneyworm: Adult and
larvae Stephanurus dentatus.
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10. FDA Status: Feed mill license required if the source of Pyrantel Tartrate contains more than 36 g/lb. (7.9%).
Regulations §558.325 and §558.485.
WARNING STATEMENT REQUIRED: Withdraw 24 hours prior to slaughter (Lincomycin). Withdraw 6 days before
slaughter (Pyrantel). Not to be fed to swine that weigh more than 250 lb.
CAUTION STATEMENT REQUIRED: Occasionally, swine fed Lincomycin may, within the first 2 days after the onset of
treatment, develop diarrhea and/or swelling of the anus. On rare occasions, some pigs may
show reddening of the skin and irritable behavior. These conditions have been self-correcting
within 5-8 days without discontinuing the Lincomycin treatment. The effects of Lincomycin on
swine reproductive performance, pregnancy and lactation have not been determined. Not for
use in swine intended for breeding when Lincomycin is fed at 20 g/ton of complete feed. Do not
allow rabbits, hamsters, guinea pigs, horses or ruminants access to feeds containing Linco-
mycin. Ingestion by these species may result in severe gastrointestinal effects. Consult your
veterinarian before feeding to severely debilitated animals and for assistance in the diagnosis,
treatment and control of parasitism. Do not mix in feeds containing bentonite. Feed as sole
ration.
VFD CAUTION: Federal law restricts medicated feed containing this Veterinary Feed Directive (VFD) drug to use by or
on the order of a licensed veterinarian.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Swine Lincomycin 40 g/ton For control of swine dysentery and the
and control of porcine proliferative enteropathy
(ileitis) caused by Lawsonia intracellularis.
Pyrantel Tartrate 96 g/ton (0.0106%) Aid in the prevention of migration and
establishment of large roundworm
(Ascaris suum) infections; aid in the
prevention of establishment of nodular
worm (Oesophagostomum spp.)
infections.
LIMITATIONS FOR USE: For use in swine on premises with a history of swine dysentery but where
symptoms have not yet occurred.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Lincomycin 100 g/ton followed by 40 g/ton For treatment and control of swine
and dysentery and the control of porcine
proliferative enteropathy (ileitis) caused by
Lawsonia intracellularis.
Pyrantel Tartrate 96 g/ton (0.0106%) Aid in the prevention of migration and
establishment of large roundworm
(Ascaris suum) infections; aid in the
prevention of establishment of nodular
worm (Oesophagostomum spp.)
infections.
LIMITATIONS FOR USE: Feed 100 g/ton for 3 weeks or until signs of disease disappear, followed by 40
g/ton.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .

218 Additive Listings | 2021 Feed Additive Compendium

 Lincomycin 100 g/ton For treatment of swine dysentery and the
and control of porcine proliferative enteropathy
(ileitis) caused by Lawsonia intracellularis.
Pyrantel Tartrate 96 g/ton (0.0106%) Aid in the prevention of migration and
establishment of large roundworm
(Ascaris suum) infections; aid in the
prevention of establishment of nodular
worm (Oesophagostomum spp.)
infections.
LIMITATIONS FOR USE: Feed 100 g/ton 3 weeks or until signs of disease disappear, followed by
40 g/ton.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Lincomycin 100 or 40 g/ton For treatment and control of swine
and dysentery and the control of porcine
proliferative enteropathy (ileitis) caused
by Lawsonia intracellularis.
Pyrantel Tartrate 96 g/ton (0.0106%). Feed for For removal and control of large
3 days as the sole ration in roundworm (Ascaris suum) infections.
a complete ration.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Lincomycin 100 or 40 g/ton For treatment and control of swine
dysentery and the control of porcine
proliferative enteropathy (ileitis) caused
by Lawsonia intracellularis.
Pyrantel Tartrate 800 g/ton (0.0881%). As a For removal and control of large
single therapeutic treatment roundworm (Ascaris suum) and nodular
in a complete feed; feed at worm (Oesophagostomum spp.)
the rate of 1 lb. of feed per infections.
40 lb. of bodyweight for
animals up to 200 lb.; and 5
lb. of feed per head for
animals 200 lb. or over.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Lincomycin 200 g/ton For reduction in the severity of
and mycoplasmal pneumonia caused by
Mycoplasma hyopneumoniae.
Pyrantel Tartrate 96 g/ton Aid in the prevention of migration and
establishment of large roundworm
(Ascaris suum) infections; aid in the
prevention of establishment of nodular
worm (Oesophagostomum spp.)
infections of swine.
LIMITATIONS FOR USE: Feed as the sole ration for 21 days.
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PRODUCT INFORMATION
Lincomycin
Trade Name: Lincomix 50 Feed Medication, Zoetis Inc., Kalamazoo, Mich. 49007; Package: 50-lb. bag; Concentration: 50 g Linco-
mycin base per pound; Carrier or Diluent: soybean hulls, #20 grind; Expiration Date: Package carries expiration date; Manufactur-
ing Suggestions: None.

Trade Name: Lincomix 20 Feed Medication, Zoetis Inc., Kalamazoo, Mich. 49007; Package: 50-lb. bags; Concentration: 20 g Linco-
mycin base per pound; Carrier or Diluent: soybean hulls, #20 grind; Expiration Date: Package carries expiration date; Manufactur-
ing Suggestions: None.
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2021 Feed Additive Compendium | Additive Listings 219