Bambermycins

CHEMICAL NAME: Bambermycins

Chickens
1. FDA Status: No feed mill license required.
Regulation §558.95
LIMITATIONS FOR USE: Feed as sole ration.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Chickens (broilers) Bambermycins 1-2 g/ton For increased rate of weight gain and
improved feed efficiency.
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COMBINATIONS ALLOWED
2. FDA Status: Feed mil license required if the source of Amprolium contains more than 11.35 g/lb. (2.5%).
Regulations §558.55 and §558.95
CAUTION: Do not use in feeds containing bentonite. Do not change the litter while giving this feed unless absolutely
necessary. If losses exceed 0.5% in a 2-day period, obtain an accurate diagnosis and follow the
instructions of your veterinarian or poultry pathologist. Losses may result from intercurrent
disease or other conditions affecting drug intake, which can contribute to the virulence of coc-
cidiosis under field conditions.
LIMITATIONS FOR USE: Feed continuously as the sole ration. Use as sole source of Amprolium.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Chickens (broilers) Bambermycins 1-2 g/ton For prevention of coccidiosis caused by
and Eimeria tenella only; and for increased
Amprolium 72.6-113.5 g/ton rate of weight gain and improved
feed efficiency.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Bambermycins 1-2 g/ton For prevention of coccidiosis where
and immunity to coccidiossi is not desired;
Amprolium 113.5-227 g/ton and for increased rate of weight gain
and improved feed efficiency.
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3. FDA Status: Feed mill license required if the source of Clopidol contains more than 11.4 g/lb. (2.5%).
Regulations §558.95 and §558.175
WARNING: Do not feed to chickens over 16 weeks of age.
CAUTION: Consult a veterinarian or poultry pathologist if losses exceed 0.5% in a 2-day period.
LIMITATIONS FOR USE: Feed continuously as the sole ration. Do not feed to chickens over 16 weeks of age.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Chickens (broilers) Bambermycins 1-2 g/ton As an aid in the prevention of coccidiosis
_ and caused by Eimeria tenella, Eimeria
_ Clopidol 113.5 g/ton necatrix, Eimeria acervulina, Eimeria
_ maxima, Eimeria brunetti and Eimeria
_ mivati; and for increased rate of weight
_ gain and improved feed efficiency.
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4. FDA Status: Feed mill license required if the source of Clopidol contains more than 11.4 g/lb. (2.5%).
Regulations §558.95 and §558.175
WARNING: Withdraw 5 days before slaughter or feed 113.5 g/ton Clopidol and 1-2 g/ton Bambermycins during those 5
days before slaughter. Do not feed to chickens over 16 weeks of age.
CAUTION: Consult a veterinarian or poultry pathologist if losses exceed 0.5% in a 2-day period.
LIMITATIONS FOR USE: Feed continuously as the sole ration until 5 days before slaughter.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Chickens (broilers) Bambermycins 1-2 g/ton As an aid in the prevention of coccidiosis
_ and caused by Eimeria tenella, Eimeria
_ Clopidol 227 g/ton necatrix, Eimeria acervulina, Eimeria
_ maxima, Eimeria brunetti and Eimeria
_ mivati; and for increased rate of weight
_ gain and improved feed efficiency.
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156 Additive Listings | 2021 Feed Additive Compendium

5. FDA Status: No feed mill license required.
Regulations §558.198 and §558.95
WARNING STATEMENT REQUIRED: Not for use in hens producing eggs for human consumption.
LIMITATIONS FOR USE: Feed continuously as the sole ration.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Chickens Bambermycins 1-2 g/ton For increased rate of weight gain and
(broilers) and improved feed efficiency.
Diclazuril 0.91 g/ton (1 ppm) For the prevention of coccidiosis caused
by Eimeria necatrix, Eimeria tenella,
Eimeria acervulina, Eimeria brunetti,
Eimeria mitis (mivati) and Eimeria
maxima. Because Diclazuril is effective
against Eimeria maxima later in its life
cycle, subclinical intestinal lesions may be
present for a short time after infection.
Diclazuril was shown in studies to reduce
lesion scores and improve performance
and health of birds challenged with
Eimeria maxima in broiler chickens.
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6. FDA Status: No feed mill license required.

Regulations §558.95 and §558.311
CAUTION STATEMENT REQUIRED: The safety of Lasalocid for use in unapproved species has not been established. Do
not allow horses or other equines access to feed containing Lasalocid as ingestion may be fatal.
LIMITATIONS FOR USE: Feed continuously as the sole ration.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Chickens (broilers) Bambermycins 1-2 g/ton For increased rate of weight gain and
and improved feed efficiency.
Lasalocid 68-113 g/ton For prevention of coccidiosis caused by
Eimeria tenella, Eimeria necatrix,
Eimeria acervulina, Eimeria brunetti,
Eimeria mivati and Eimeria maxima.
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7. FDA Status: No feed mill license required.

Regulations §558.95 and §558.355
WARNING STATEMENT REQUIRED: Do not feed to laying chickens. Do not feed to chickens over 16 weeks of age.
Feed continuously as sole ration.
CAUTION: Do not allow horses or other equines access to formulations containing Monensin. Ingestion of Monensin
by equines has been fatal. In the absence of coccidiosis, the use of Monensin with no with-
drawal period may limit feed intake resulting in reduced weight gains.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Chickens (broilers) Bambermycins 1-2 g/ton As an aid in the prevention of
and coccidiosis caused by Eimeria necatrix,
Monensin 90-110 g/ton Eimeria tenella, Eimeria acervulina,
Eimeria brunetti, Eimeria mivati and
Eimeria maxima; for increased rate of
weight gain and improved feed efficiency.
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8. FDA Status: No feed mill license required.

Regulations §558.95 and §558.363
CAUTION: Do not allow adult turkeys, horses or other equines access to formulations containing Narasin. Ingestion
of Narasin by these species has been fatal.
LIMITATIONS FOR USE: For broiler chickens only. Feed continuously as the sole ration.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Chickens (broilers) Bambermycins 1-2 g/ton For the increased rate of weight gain
and and improved feed efficiency.
Narasin 54-72 g/ton For the prevention of coccidiosis caused
by Eimeria necatrix, Eimeria tenella,
Eimeria acervulina, Eimeria brunetti,
Eimeria mivati and Eimeria maxima.
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Bambermycins (Continued)
9. FDA Status: Feed mill license required if the source of Narasin/Nicarbazin contains more than 5.675 g/lb.
(1.25%).
Regulations §558.363, §558.366 and §558.95
WARNING STATEMENT REQUIRED: Feed containing Narasin/Nicarbazin must be withdrawn 5 days prior to slaughter.
Feed continuously as the sole ration. Do not feed to laying hens.
CAUTION STATEMENT REQUIRED: Do not allow adult turkeys, horses or other equines access to formulations con-
taining Narasin. Ingestion of Narasin by these species has been fatal. [Nicarbazin medicated
broilers may show reduced heat tolerance if exposed to high temperature and high humidity.]
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Chickens (broilers) Bambermycins 1-2 g/ton For increased rate of weight gain and
and improved feed efficiency.
Narasin/Nicarbazin 54-90 g/ton of the combination For the prevention of coccidiosis in
broiler chickens caused by Eimeria
necatrix, Eimeria tenella, Eimeria
acervulina, Eimeria brunetti, Eimeria
mivati and Eimeria maxima.
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10. FDA Status: Feed mill license required if the source of Nicarbazin contains more than 5.675 g/lb. (1.25%).
Regulations §558.95 and §558.366
WARNING STATEMENT REQUIRED: Withdraw 4 days before slaughter. Do not feed to laying hens. Do not use in flush-
ing mashes.
CAUTION: Do not use as a treatment for coccidiosis. Broiler chickens fed feed medicated with Nicarbazin may show
reduced heat tolerance when exposed to high temperatures and high ambient humidity to which
they have not been accustomed, and under severe conditions, fatalities may result. An ample
supply of drinking water and adequate ventilation will improve the birds’ tolerance of heat.
LIMITATIONS FOR USE: Feed continuously as sole ration from time chicks are placed on litter until past the time
when coccidiosis is ordinarily a hazard.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Chickens (broilers) Bambermycins 1-2 g/ton Increased rate of weight gain and
and improved feed efficiency.
Nicarbazin 113.5 g/ton Aid in preventing outbreaks of cecal
(Eimeria tenella) and intestinal (Eimeria
acervulina, Eimeria maxima, Eimeria
necatrix and Eimeria brunetti) coccidiosis
in chickens.
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11. FDA Status: No feed mill license required.

Regulations §558.95
WARNING STATEMENT REQUIRED: Do not feed to laying chickens.
CAUTION STATEMENT REQUIRED: Not approved for use with pellet binders. May be fatal if accidentally fed to adult
turkeys or horses.
LIMITATIONS FOR USE: Feed continuously as sole ration. Must be thoroughly mixed in feeds before use.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Chickens (broilers) Bambermycins 1-3 g/ton For prevention of coccidiosis caused by
and Eimeria tenella, Eimeria necatrix,
Salinomycin 40-60 g/ton Eimeria acervulina, Eimeria brunetti,
Eimeria mivati and Eimeria maxima.
For improved feed efficiency.
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12. FDA Status: No feed mill license required.

Regulations §558.95 and §558.680
WARNING STATEMENT REQUIRED: Do not feed to chickens over 14 weeks of age.
CAUTION: Feed continuously as the sole ration. Consult a veterinarian or poultry pathologist if losses exceed 0.5% in
a two-day period.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Chickens (broilers) Bambermycins 1 g/ton As an aid in the prevention and control
and of coccidiosis. For increased rate of
Zoalene 113.5 g/ton (0.0125%) weight gain, and improved feed
efficiency.
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158 Additive Listings | 2021 Feed Additive Compendium

 Turkeys
13. FDA Status: No feed mill license required.
Regulation §558.95
LIMITATIONS FOR USE: Feed continuously as sole ration.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Turkeys (growing) Bambermycins 1-2 g/ton For improved feed efficiency.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Bambermycins 2 g/ton For increased rate of weight gain and
improved feed efficiency.
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COMBINATIONS ALLOWED
14. FDA Status: Feed mill license required if the source of Amprolium contains more than 11.35 g/lb. (2.5%).
Regulations §558.95 and §558.55
LIMITATIONS FOR USE: Feed continuously as sole source of Amprolium.
CAUTION: DO not use Amprolium in feeds containing bentonite.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Turkeys (growing) Bambermycins 1-4 g/ton Prevention of coccidiosis; for
and increased rate of weight gain and
Amprolium 113.5 g/ton (0.0125%) improved feed efficiency.
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15. FDA Status: No feed mill license required.

Regulations §558.198 and §558.95
WARNING STATEMENT REQUIRED: Not for use in hens producing eggs for human food.
CAUTION: Do not feed to breeding turkeys.
LIMITATIONS FOR USE: Feed continuously as sole ration.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Growing Bambermycins 1-2 g/ton For improved feed efficiency in growing
turkeys and turkeys.
Diclazuril 0.91 g/ton (1 ppm) For the prevention of coccidiosis
caused by Eimeria adenoeides, Eimeria
gallopavonis and Eimeria meleagrimitis
in growing turkeys.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Bambermycins 2 g/ton For increased rate of weight gain and
and improved feed efficiency in growing
turkeys.
Diclazuril 0.91 g/ton (1 ppm) For the prevention of coccidiosis
caused by Eimeria adenoeides, Eimeria
gallopavonis and Eimeria meleagrimitis
in growing turkeys.
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16. FDA Status: No feed mill license required.

Regulations §558.95 and §558.355
WARNING STATEMENT REQUIRED: Feed continuously as sole ration.
CAUTION STATEMENT REQUIRED: Do not allow horses or other equines access to feed containing Monensin. Inges-
tion of Monensin by equines has been fatal. Some strains of turkey coccidia may be Monensin
tolerant or resistant. Monensin may interfere with the development of immunity to turkey coc-
cidiosis.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Turkeys Bambermycins 1-2 g/ton For increased rate of weight gain and
and improved feed efficiency.
Monensin 54-90 g/ton For the prevention of coccidiosis
caused by Eimeria adenoeides, Eimeria
gallopavonis and Eimeria meleagrimitis.
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2021 Feed Additive Compendium | Additive Listings 159

Bambermycins (Continued)
Swine
17. FDA Status: No feed mill license required.
Regulation §558.95
LIMITATIONS FOR USE: Feed continuously as sole ration.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Swine (growing and Bambermycins 2 g/ton For increased rate of weight gain and
finishing) improved feed efficiency.
. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . .
Bambermycins 2-4 g/ton For increased rate of weight gain.
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Cattle
18. FDA Status: No feed mill license required.
Regulation §558.95
LIMITATIONS FOR TYPE B LIQUID FEED: Expiration date - 8 weeks after the date of manufacture,
pH 3.8 to 7.5 and moisture content of 30 to 45%.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Cattle (fed in Bambermycins 1-4 g/ton (Feed continuously For increased rate of weight gain and
confinement for in Type C feed to provide not improved feed efficiency.
slaughter) less than 10 nor more than 20 mg
Bambermycins/head/day
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19. FDA Status: No feed mill license required.

Regulation §558.95
LIMITATIONS FOR USE: Feed continuously at a rate of 10-40 mg/head/day in at least 1 lb. and not more than 10 lb.
of feed. Daily Bambermycins intakes in excess of 20 mg/head/day have not been shown to be
more effective than 20 mg/head/day.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Pasture cattle Bambermycins 2-80 g/ton For increased rate of weight gain.
(slaughter, stocker,
and feeder cattle,
and dairy and beef
replacement heifers)
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160 Additive Listings | 2021 Feed Additive Compendium

20. FDA Status: No feed mill license required.
Regulation §558.95
LIMITATIONS FOR USE: Free-choice supplements must be formulated to provide 10-40 mg/head/day Bambermycins.
Each use in a free-choice Type C medicated feed must be the subject of an approved new
animal drug application (NADA) or supplemental NADA as required by 21 CFR §510.455. Feed
mills that use a proprietary formula are required to be licensed. Daily Bambermycins intakes in
excess of 20 mg/head/day have not been shown to be more effective than 20 mg/head/day.
ANIMAL DRUG USE LEVEL INDICATIONS FOR USE
Pasture cattle Bambermycins 10-40 mg/head/day For increased rate of weight gain.
(slaughter, stocker,
and feeder cattle,
and beef replacement
heifers)
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PRODUCT INFORMATION
Bambermycins
Trade Name: Flavomycin and GAINPRO, Huvepharma EOOD, 5th Floor, 3A Nikolay Haytov Str., Sofia 1113, Bulgaria; Manufac-
tured by: Huvepharma Inc., St. Louis, Mo. 63116; Distributed by: Huvepharma Inc., 525 Westpark Dr., Suite 230, Peachtree City, Ga.
30269; Package: Flavomycin - 50-lb. multi-wall bags; GAINPRO - 50-lb. multi-wall bags; Concentration: Flavomycin - 4 g Bamber-
mycins/lb.; GAINPRO - 10 g Bambermycins/lb.; Carrier or Diluent: Roughage products: Expiration Date: Flavomycin - 24 months;
GAINPRO - 24 months; Manufacturing Suggestions: See label.
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Banminth
(see Pyrantel Tartrate)

Bio-Cox
(see Salinomycin)

Bloat Guard
(see Poloxalene)

BMD
(see Bacitracin Methylenedisalicylate)

Bovatec
(see Lasalocid)

2021 Feed Additive Compendium | Additive Listings 161