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4. Biotransformation of a medicinal substance results in: a) faster urinary excretion b) slower urinary excretion c) easier distribution in organism d) higher binding to membranes 5. All are cardioselective beta blockers EXCEPT: a) metaprolol b) bisoprolol c) acebutalol d) propranolol 6. Which is the mast cell stabilizer used in prophylaxis of asthma? a) terbutaline b) aminophylline Cc) sodium cromoglycate d) tiotropium bromide 7. Allare atypical antipsychotics EXCEPT: a) amisulpiride b) olanzapine ¢) quetiapine d) haloperidol 8. The site of action of thiazide diuretic is: a) Na *- CI transporter b) Na*-K*-2CI transporter c) Na*-H* antiporter d) Na*-HCO3° symporter 9. All are antileprosy drugs EXCEPT: a) dapsone b) clofazimine c) rifampin d) amphotericin B 10. B-lactum antibiotics do not include the following: a) streptomycin b ¢) carbapenems cephalosporins d) monobactams QP Code: 1207 JSS UNIVERSITY, MYSORE Second Year BDS Examination - June 2014 Subject: General & Dental Pharmacology & Therapeutics Note: All questions are compulsory. Your answers should be specific to the questions asked. Draw neat labeled diagrams wherever necessary. im e: 3 hours Max. Marrs: 7* I, LONG ESSAYS 2x10=20 Marrs Describe the role of disclosing agents and fluorides in dentistry. 2. Classify anti hypertensives. Explain the mechanism of action, uses and adverse effects of angiotensin converting enzyme inhibitors. ll. SHORT ESSAYS 6x5=30 Marks 3. Intravenous general anaesthetics. . 4. Pharmacological actions and uses of lignocaine. 5. Succinylcholine. 6. Mechanism of action, uses and adverse effects of heparin. 7. Metronidazole. 8. Chemoprophylaxis. Il. SHORT ANSWERS 10x2=20 Marks 9. Explain the rationale for the use of combination of clavulanic acid and amoxicillin. 10. Name four oral antidiabetic drugs and explain the mechanism of any one. 11. Mention two therapeutic uses of adrenaline and explain the basis in any one condition. 12. Mention the advantages and disadvantages of intravenous route of drug administration. 13. Write briefly on omeprazole. 14. Name two mucolytics and two antitussives used to treat cough. 15. Name four drugs that prevent bone resorption. 18. Compare diphenhydramine with loratidine. Outline the short course chemotherapy regimen in treatment of tuberculosis. Mention two contraindications for aspirin use and explain the rationale for it eee QP God, 1a0¢ JSS UNIVERSITY, MYSORE Ology & Therapeutics Note: Aj) que. . : Stions are compulsory. Your ’ ; are Mpulsory Danswers Should be Specific to the questions asked 'eW neat labeleg diagrams yo nS wi erever necessary hours Max. Marks: 70 NG ESSAYS t are dentit 2x10=20 Marks at Entiftices? Ntifrices Explain the Actions of Various WNgredients aSsify local anestheti: y “sed in S and explai 1Ocal anest aline With loc: iwo techniques of Nits Mechanism of act Nale for USING adren; lon. Des "Sie Used We Gent al anesthetic Vike the HORT Essays jactors Modifying Srug action 8x5=30 Marks Sf atropine. "st line '8in the mechanism of action of frusemide and mention two uses Tt€ tWO Uses and WO adverse ef Name tw Ne fects of phe Fyicin sodium © 4, blockers and their two uses drug used in acure anginal attack anc explain the basis for its Explain Crug tolerance with an example two advantages of amlodipine over nifedipine, © mummifying agents and Give two exam) @ two ples nasal decongestants and explain their limi tations four adverse effects of tetracyclines ice fi ‘dosage and its basis “ION drug of choice for acute paracetamol overdosage and it: SI Time: I. Nn Oo Bw o o QP Code: 1207 JSS UNIVERSITY, MYSORE subj Second Year BDS Examination - June 2043 uDject: General & Dental Pharmacology & Therapeutics Note: Ajj questions are y, © compulsory. ou answers Should be specific to the questions asked. Taw neat labeled diagrams wherever necessary. 3 hours Max. Marks: 70 LONG ESSAYS 2x10=20 Marks What are mouthwashes? Describe four substances used as mouthwashes Classify NSAIDs, Describe the pharmacological” actions, ibuprofen Mechanism of action, main adverse effects and therapeutic uses of SHORT ESSAYS 6x5=30 Marks Therapeutic uses of adrenaline Phase | reactions with examples. Mechanism of actions and therapeutic uses of glyceryl trinitrate Precautions and contra-indications for morphine. Mechanism of action and therapeutic uses of doxycycline Life saving indications for glucocorticoids SHORT ANSWERS 10x2=20 Marks Mention adverse effects of ACE inhibitors Mention two drugs each for treatment and prevention of migraine Mention two drugs each, used as relievers and preventors in bronchial asthma. Mention four anti-emetics of different classes Classify the drugs used in amoebiasis Mention four therapeutic uses of chloroquine Classify anti-thyroid drugs with examples Mention four uses of ascorbic acid Name two local anaesthetic and two general anaesthetics Mention four adverse effects of cephalosporins : QP Code: 14297 Subject: General & Dental Pharmacology & Therapeutics Part Il LONG ESSAY Classify sympathomimetics based on their therapeutic uses with suitable examples. Enumerate indications and contraindications of adrenaline Explain the rationale for adding adrenaline to lignocaine Classify antihypertensive drugs. Describe the mechanism of action. therapeutic uses and adverse effects of ACE-inhibitors 2x10=20 Marks SHORT ESSAY 4x5= 20 Marks Pharmacotherapy of anaphylactic shock Describe the mechanism of action, therapeutic uses and adverse effects of penicillin Name two anti caries agents and explain their mechanism of action Name four first line anti tubercular drugs. Mention one adverse effect of each drug. SHORT ANSWERS 10X2=20 Marks Enumerate four clinical uses of diazepam Enumerate the adverse effects of furosemide. Name four drugs used in acid peptic diseases. Therapeutic uses of local anesthetics Name two therapeutic uses and two adverse effects of insulin Name two inhalational glucocorticoids and mention two adverse effects. Mention two therapeutic applications of antiseptics in dental practice. Name two therapeutic uses and adverse effects of chloroquine Mention four drugs given through transdermal route Advantages of low molecular weight heparin Page 3 of 3 QP Code: 1207 Jss Academy of Higher Education & Research, Mysuru (Deemed to be University) Second Year BDS Examination - December 2019 Subject: General & Dental Pharmacology & Therapeutics Note: All questions are compulsory. Your answers should be specific to the questions asked. Draw neat labeled diagrams wherever necessary. ne: 3 hours Max. Marks: 70 LONG ESSAYS 2x10=20 Marks 1. Describe the pharmacology of antiplaque and anti-gingivitis agents. 2. Define analgesia. Enumerate opioid analgesics. Describe the mechanism (2+2+4+2) of action and therapeutic uses of morphine. Add a note on the role of opioids in dental pain. |. SHORT ESSAYS 6x5=30 Marks 3. Propofol. 4. Fixed dose combination. 5. Therapeutic uses of atropine. 6. Domperidone. 7, Warfarin. 8. Newer macrolides. il. SHORT ANSWERS 10x2=20 Marks 9, What are the drugs used in the treatment of lepra reaction? 10. What is DOTS? What are the drugs given under this programme? 11. What is dantrolene sodium? Where is it used? 12. Name two drugs that produce nephrotoxicity. 13. What is the mechanism of action of radioactive iodine? 14. Uses of methotrexate. Justify the use of adrenaline with lignocaine. Mention the rationale in the use of spironolactone in congestive cardiac failure (CCF) Mention two alpha glucosidase inhibitors and their indications. What is the rationale in combining aluminium and magnesium salts in antacids? fete a Vv» ~ QP Code: 1207 ASS UNIVERSITY, MYSURU Second Year BDS Examination - June 2017 Subject: General & Dental Pharin. “ology & Therapeutics Note: All questions are compulsory Your answers Should be specific to the questions asked Diaw neat labeled diagrams wherever necessaly. + hours Max. Marks: 70 LONG ESSAYS 2x10=20 Marks Define and classify dentiftices. Describe the pharmacology of detergents (3+3+4) Describe the spectrum of action, adverse reactions and uses of (4+3+3) noxicillin : SHORT ESSAYS 6x5=30 Marks Adverse reactions and uses of atropine. (32) What are transdermal therapeutic systems? Mechanism of action and uses of digoxin. (3+2) Mechanism of action and uses of omeprazole (3+2) Adverse reactions and uses of morphine. _ (342) Mechanism of action and adverse reactions of heparin. (3+2) SHORT ANSWERS 40x2=20 Marks Name four fluoroquinolones. Write four uses of conventional anti-histamines. Uses of adrenaline. List two techniques for administration of local anaesthesia. Mechanism of action of desferrioxamine. Enumerate four drugs useful in grand mal ‘epilepsy. Mechanism of ACE inhibitors: Drugs for pernicious anaemia Four non-endocrine uses of prednisolone Mechanism of action of acyclovir. J503. Lis S$.5.NAGAR, MAYS: a Code, 126 48S UNIVERSITY. MYSORE Second Year BBS Examina Subject: General & Denta on -Dec 2043 { Pharmacology & Therapeutics Note: All questions are compulsory Your answers should be speci ific to the questions asked Oraw neat labeled diagrams wherever necessary rime: 3 hours Max. Marks: 70 ) LONG ESSAYS 2x10=20 Marks Define and classify obtundents. Describe obtundents acting by paralyzing sensory nerve endings. Classify non steroidal anti-inflammatory agents. Describe mechanism of action, therapeutic uses and adverse effects of paracetamol. I. SHORT ESSAYS 6x5=30 Marks Therapeutic uses of adrenaline. . Factors affecting excretion of drugs in urine. Describe drug treatment of status epilepticus. Name thiazide diuretics. Describe their therapeutic uses and adverse crug reactions. Describe therapeutic uses of vit Ds; Describe therapeutic uses of 3 generation cephalosporins ill. SHORT ANSWERS 10x2=20 Marks 3. Routes of administration and antidote of heparin. 10. Enumerate first line drugs used in the treatment of pulmonary tuberculosis ‘1, Name two osmotic diuretics and their therapeutic uses. 12 Name four groups of atropine substitutes depending on their mechanism of action. 12. Name four groups of drugs used in long term management of angina. | 14. Mention two therapeutic uses and two adverse drug reactions of H, antagonists. ‘5. Enumerate advantages of human insulin. 18. Name drugs used in the treatment of oral candidiasis. 17, Name two opioid antagonists and their therapeutic uses. 18, What is a disinfectant? Name two uses of disinfectants in clinical practice. val ime: 16, 17, 18. QP Code: 1207 JSS Academy of Higher Education & Research, Mysuru (Deemed to be University) Second Year BDS Examination — January 2021 Subject: General & Dental Pharmacology & Therapeutics Note: All questions are compulsory. Your answers should be specific to the questions asked. Draw neat, labeled diagrams wherever necessary. 3 hours LONG ESSAYS Classify anti-hypertensive drugs. Explain the mechanism of action, uses and adverse effects of calcium channel blockers. Enumerate the common oral conditions in dentistry. Explain the role of various anti-microbials in the management of these conditions. SHORT ESSAYS Combined effect of drugs. Mechanism of action, uses and adverse effects of lignocaine. Haematinics. Bronchodilators. Warfarin. Newer macrolides. SHORT ANSWERS Write TWO advantages of sublingual route with TWO examples. Define teratogenicity. Give ONE example. Define astringent. Give ONE example. Name TWO skeletal muscle relaxants with TWO uses. Name TWO osmotic purgatives. Mention TWO specific adverse effects. Name TWO coagulants. Give TWO specific uses. Name TWO antiviral drugs belonging to two different groups. Write ONE use of each. List the adverse effects of tetracyclines on bone and teeth. Name TWO fluoroquinolones. Write TWO specific adverse effects. Write the mechanism of action and uses of desferrioxamine. tke Max. Marks: 70 2x10=20 Marks (5+1+2+2) (4+6) 6x5=30 Marks 10x2=20 Marks QP Code: 1207 JSS UNIVERSITY, MYSORE Second Year BDS Examination - December 2010 Subject: General & Dental Pharmacology & Therapeutics Note: All questions are compulsory. Your answers should be specific to the questions asked. Draw neat labeled diagrams wherever necessary. ime: 3 hours Max. Marks: 70 |, LONG ESSAYS 2x10=20 Marks 4, Enumerate dental desensitizing agents. Add a note on obtundents. 2. Classify Beta-lactum antibiotics. Describe the mechanism of action, adverse effects and uses of cephalosporins ll, SHORT ESSAYS 6x5=30 Marks eo Channels of excretion of drugs with examples. = Lignocaine o Propranolol. o Hydrocortisone 7. Mechanism of action & uses of neostigmine. 8. Vitamin D. lil. SHORT ANSWERS 10x2=20 Marks 9. Name four antacids 10. Mention four drugs used for constipation Uses and adverse effects of amphotericin B. Mention four intravenous anaesthetics 13. Name four prokinetic drugs. Name four sulfonylureas Mention two chelating agents and their uses Mention four uses of anticholinergics Mention four anticancer drugs. Mention four different groups of diuretics QP Code: 11207 JSS UNIVERSITY, MYSURU Second Year BDS (RS 1) December 2017 Subject: General & Dental Pharmacology & Therapeutics jme: 3 hours Max. Marks: 70 Your answers should be specific to the questions asked. Draw neat labeled diagrams wherever necessary Partl | Multiple Choice | : | 10 Marks To be answered in OMR sheet | Questions part Il | Long Essay ( 2X10 Marks) 20 Marks To be answered in Answer | Short Essay ( 4X05 Marks) | 20 Marks Booklet : | Short Answers A 10X02 Marks) | 20 Marks Part | Multiple Choice Questions 40 x 1=10 Marks Note: 1. Answer ALL the questions in the OMR Sheet given by using BLACK/BLUE BALL POINT PEN ONLY 2. Choose the ONE CORRECT ANSWER from the 4 choices given for each question 3. Maximum time for answering Part lis 10 minutes. 1. At the end of 10 minutes, submit the OMR sheet to the Invigilator. 1. Aprodrug is: a) the prototype member of a class of drugs b) the oldest member of a class of drugs c) an inactive drug that is transformed in the body to an active metabolite d) adrug that is stored in body tissues and is then gradually released in the circulation 2, Which of the following Is the only life saving measure in case of anaphylactic shock? a) intravenous hydrocortisone hemisuccinate b) intravenous chlorpheniramine maleate c) intramuscular adrenaline hydrochloride d) intravenous glucose saline: There is no alternative to insulin therapy for we a) all type 1 diabetes mellitus patients b) all type 2 diabetes mellitus patients :) type 2 diabetes patients not controlled by a sulfonylurea drug 1) type 2 diabetes patients not controlled by a biguanide drug Page 1of3 All are anti-thyroid drugs EXCEPT a) propylthiouracil b) _methimazole c) carbimazole d) carbamazepine All are atypical anti-psychotic drugs EXCEPT: a) clozapine b) risperidone c) olanzapine d) loxapine Local anaesthetics: a) block the release of neurotransmitters b) block the influx of sodium into the cell c) increase the release of inhibitory neurotransmitters d) inhibit the efflux of sodium from neurons All are anti-platelet drugs EXCEPT: a) aspirin b) clopidogrel c) dipyridamole d) warfarin Advantage of salmeterol over salbutamol is its: a) shorter duration of action b) more potency c) longer duration of action d) lesser cardiac effects Ondansetron acts by inhibiting which of the following receptors? a) 5-HT1 b) 5-HT2 c) 5-HT3 d) 5-HT4 10. An aminoglycoside which is resistant to majority of inactivating enzymes is: a) gentamycin b) amikacin c) tobramycin d) sisomycin Page 2 Time: On OW & 10. 11. 12. 13. 14, a ~ oo QP Code: 1207 JSS UNIVERSITY, MYSURU Second Year BDS Examination - December 2016 Subject: General & Dental Pharmacology & Therapeutics Note: All questions are compulsory Your answers should be specific to the questions asked. Draw neat labeled diagrams wherever nec ry. 3 hours LONG ESSAYS Classify antiseptics used in dental practice. Describe the pharmacology of oxidizing agents and halogens. Write the mechanism of action, adverse effects and uses of angiotensin converting enzyme inhibitors. SHORT ESSAYS Therapeutic index. Mechanism of action and uses of sodiu Adverse effects and uses of propranolol Mechanism of action and uses of verapamil. m valproate. Uses of prostaglandins. Adverse effects and uses of nitrates. SHORT ANSWERS Four factors modifying drug response. Name two oral and two parenteral iron preparations. Name four groups of oral antidiabetics Name four aminoglycosides our drugs for treatment of anaerobic infections. Name f Mention four chelating agents. Mechanism of action of bisphosphonates. Treatment of warfarin toxicity. Drugs for acute attack of asthma. Rationale for combination of adrenaline with lignocaine. Max. Marks: 70 2x10=20 Marks (4+3+3) (3+3+4) 6x5=30 Marks 40x2=20 Marks QP Code: 11207 JSS Academ y of Higher Education and Research Second Ye ar BDS (RS 1) Examination - December 2018 Subject: General & Dental Pharmacology & Therapeutics : 3 hours Max. Marks: 70 Your answers should be specific to the questions asked. Draw neat labeled diagrams wherever necessary. |__| Multiple Choice Questions Yay 10 Marks | To be answered in OMR sheet | " _Long Essays ee Ta Marks ~ | To be answered in Answer | _Short Essays | 20Marks | Booklet —_|StotAnswers [20 Marks Part | Itiple Choice Questions 10x 1=10 Marks te: 1. Answer ALL the questions in the OMR Sheet given by using BLACK/BLUE BALL POINT PEN ONLY. 2. 3. 4. Choose the ONE CORRECT ANSWER from the 4 choices given for each question. Maximum time for answering Part | is 10 minutes. At the end of 10 Minutes, submit the OMR sheet to the Invigilator. The antidote used in the treatment of atropine Poisoning is: a) physostigmine b) carbachol Cc) neostigmine d) adrenaline All are inhalational glucocorticoids EXCEPT: a) beclomethasone dipropionate b) budesonide Cc) prednisolone d) fluticasone 3. Which is the long acting insulin analogue? a) regular insulin b) insulin lente ¢) insulin glargine d) insulin lispro Page 1of3 QP Code: 1207 JSS UNIVERSITY, MYSORE Second Year BDS Examination - June 2010 Subject: General & Dental Pharmacology & Therapeutics Note: All questions are compulsory. Your answers should be specific to the questions asked. Draw neat labeled diagrams wherever necessary. 3 hours Max, Marks: 70 LONG ESSAYS 2x10=20 Marks What are dentifrices? Mention the ideal requirements of dentifrices with examples. ify analgesics Describe the pharmacological actions, adverse affects and uses of acetyl salicylic acid SHORT ESSAYS 6x$=30 Marks Diug synergism with examples. Calcium channel blockers. Varfarin sodium amin C |. (Dimercaprol) Surgatives. SHORT ANSWERS 0 Marks wiention fou uses of furosemide ‘on four preparations of iron. \ lention four drugs used in tuberculosis ieniion four non-sedative anti-histaminics Therapeutic uses chloroquine Mechanism of action & adverse effects of panicillins antion the advantages of sublingual route of drug administration Complications of general anaesthesia Mention adverse effects of phenytoin sodium Clinical uses of ethyl alcohol QP Code: 11207 JSS UNIVERSITY, MYSURU Second Year BDS (RS 1) June 2017 Subject: General & Dental Pharmacology & Therapeutics 3 hours * Max. Marks: 70 Your answers should be Specific to the questions asked. Oraw neat labeled diagrams wherever necessary | MultipleChoice | | 10 Marks | To be answered in OMR sheet | Questions | Il | Long Essay — | ( 2X10 Marks) 20 Marks To be answered in Answer | | Short Essay (4X05 Marks) | 20 Marks Booklet | Short Answers | (19X02 Marks) | 20 Marks | Part | Itiple Choice Questions 10 x 1= 10 Marks te: 1. Answer ALL the questions in the OMR Sheet given by using BLACK/BLUE BALL POINT PEN ONLY 5 2. Choose the ONE CORRECT ANSWER from the 4 choices given for each question. 3. Maximum time for answering Part | is 10 minutes. 4. At the end of 10 minutes, submit the OMR sheet to the Invigilator. Metronidazole is used in periodontal abscess because of its activity against: a) Entamoeba histolytica b) Giardia lamblia c) Anaerobic bacilli d) Aerobic gram positive cocci Morphine has high affinity for the following opioid receptor(s): a) qt (Mu) b) « (Kappa) c) 6 (Delta) d) Opioid receptor like1 (ORL1) Drug administered through the following route is most likely to be subjected to first-pass metabolism: a) Oral b) Sublingual c) Subcutaneous d) Intravenous Page 1 of 3 Uri: “NAGAR, MYSCK | QP Code: 14 Subject: General Dental Pharmacology & Therapeutics au Part Il SSAY LONG E 2x10=20 Marks Define and classify antiseptics and disinfectants Write the mechanism of (14242+3+2) action and uses of oxidizing agents. Add a note on obtundents. Write the uses and adverse effects of (2+2+2+4) anticholinesterases. Compare and contrast neostigmine and physostigmine. Classify anticholinesterases, SHORT ESSAY 4x5=20 Marks Compare and contrast halothane and ether. Four examples and uses proton pump inhibitors, (2+3) Mechanism of action and uses of phenytoin. (2+3) Name four pre-anaesthetic medications with their specific purpose (2+3) SHORT ANSWERS 10x2= 20 Marks Indications of oral rehydration solution (ORS). Treatment of anaphylactic shock. Mucolytics 0. Four uses of metronidazole. Name two antipsychotics and two selective serotonin reuptake inhibitors. 2. Tramadol Treatment of paracetamol poisoning ‘Two examples and two uses of non-sedative antihistaminics. 5 Name two beta blockers and their uses. Bleaching agents. elk Page 3 of 3 ™ QP Code: 11207 JSS Academy of Higher Education & Research, Mysuru (Deemed to be University) Second Year BDS (RS 1) Examination — December 2019 Subject: General and Dental Pharmacology and Therapeutics Max. Marks: 70 Time: 3 hours Note: All questions are compulsory. Your answers should be specific to the questions asked. Draw neat labeled diagrams wherever necessary. To be answered in OMR sheet | Part V ] Multiple Choice Questions | 40 Marks [ Part Il - [ Long Essays "20 Marks To be answered in Answer "Short Essays : “20 Marks Booklet | Short Answers —_ : | 20 Marks : Part! 410 x 1=10 Marks Multiple Choice Questions Note: 1. Answer ALL the questions in the OMR Sheet given by using BLACK/BLUE BALL POINT PEN ONLY. Choose the ONE CORRECT ANSWER from the 4 choices given for each question. 2. 3. Maximum time for answering Part | is 10 minutes. , 4. Atthe end of 10 minutes, submit the OMR sheet to the Invigilator. The antidote used in the treatment of the organophosphorus poisoning is: a) atropine b) adrenaline c) atenolol d) ampicillin All are side effects of thiazide diuretics EXCEPT: 2 a) hyperglycemia b) hypokalemia c) hyponatremia d) hypocalcemia The anti-thyroid drug that lowers the functional capacity of the hyperactive thyroid gland is: 3 a) carbimazole b) insulin c) furosemide d) glucocorticoids Page 10f3 QP Code: 1207 JSS UNIVERSITY, MYSURU Second Year BDS Examination - June 2016 Subject: General & Dental Pharmacology & Therapeutics Note: All questions are c ‘compulsory. Your answers should be specific to the questions asked. Draw neat labeled diagrams wherever necessary. s 3 hour: Max. Marks: 70 SAYS LONG ES 2x10=20 Marks Classify antiseptics and disinfectants used in dentistry. Describe the (5+5) pharmacology of oxidizing agents and halogens. Classify beta-lactam antibiotics. Describe the mechanism of action, (2+2+2+2+2) anti-microbial spectrum, adverse effects and therapeutic uses of ampicillin. SHORT ESSAYS 6x5=30 Marks Mechanism of action and therapeutic uses of physostigmine. Differences between competitive and non-competitive antagonism. Mechanism of action and therapeutic uses of ramipril. Adverse effects and therapeutic uses of carbamazepine. Mechanism of action and adverse effects of metronidazole Mechanism of action of DPP-4 inhibitors and status in therapy of T2DM SHORT ANSWERS 10x2=20 Marks Mention four adverse effects of thiazide diuretics Mention four therapeutic uses of anti-histaminics. Mention four drug interactions with warfarin. Mention the ingredients of anti H pylori treatment. Name the drugs in AKT 4 kit Mention four contra-indications to tetracyclines Mention four therapeutic uses of methotrexate. Mention four uses of vitamin D, excluding rickets Basis of combining adrenaline with local anaesthetic. Mention four adverse effects of aminoglycosides USS. DENTAL CC marty S.S.NAGAR, MYSORE-570 015 | QP Code: 1207 JSS UNIVERSITY, MYSORE Second Year BDS Examination - June 2012 Subject: General & Dental Pharmacology & Therapeutics Note: All questions are compulsory. Your answers should be specific to the questions asked. Draw neat labeled diagrams wherever necessary. re: Shours "Max. Marks: 70 LONG ESSAYS 2x10=20 Marks What are dentifrices? Describe four substances used as dentifrices. Define and classify local anesthetics. Describe their dynamics, kinetics and uses. SHORT ESSAYS 6x5=30 Marks Mechanism of action and therapeutic uses of salbutamol. Agonists and antagonists of cholinergic receptors. Therapeutic uses of calcium channel blockers. Mechanism of action & adverse effects of cephalexin. Actions and therapeutic uses of diazepam Classify oral anti-diabetic drugs with an example of each. SHORT ANSWERS ” 40x2=20 Marks Mention four uses of loop diuretics. Name four limitations of oral route of drug-administration. Mention four atropine substitutes. List four contra-indications for beta blockers. List four aims of pre-anesthetic medication. Name four anti-platelet drugs. Classify laxatives with an example of each. Mention four classes of anti-cancer drugs with an example of each. Name four classes of anti-malarial drugs with an example of each. Mention four anti-viral drugs. ARY AR, MYSORE-570 015 QP Code: 11207 JSS UNIVERSITY, MYSURU Second Year BDS (RS 1) December 2017 Subject: General & Dental Pharmacology & Therapeutics rime: 3 hours Max. Marks: 70 Your answers should be specific to the questions asked. Draw neat labeled diagrams wherever necessary Part! | Multiple Choice ~ | 40 Marks | Tobe answered in OMR sheet ___| Questions Partll | Lon ~~ 109X410 Marks) 190 Marke essay 2X10 Marks) 20 Marks | To be answered in Answer Ee ___| (4X05 Marks) | 20 Marks Booklet _| Short Answers (40X02 Marks) | 20 Marks . Part Multiple Choice Questions 10x 1=10 Marks Note: |. Answer ALL the questions in the OMR Sheet given by using BLACK/BLUE BALL POINT PEN ONLY. 2. Choose the ONE CORRECT ANSWER from the 4 choices given for each question. 3. Maximum time for answering Part | is 10 minutes. 4. At the end of 10 minutes, submit the OMR sheet to the Invigilator. 1. A prodrug is: a) the prototype member of a class of drugs b) the oldest member of a class of drugs c) an inactive‘drug that is transformed in the body to an active metabolite d) a drug thatis stored in body tissues and is then gradually released in the circulation 2. Which of the following is the only life saving measure in case of anaphylactic shock? a) intravenous hydrocortisone hemisuccinate b) intravenous chlorpheniramine maleate c) intramuscular adrenaline hydrochloride d) intravenous glucose saline. 3. There is no alternative to insulin therapy for: a) all type 1 diabetes mellitus patients b) all type 2 diabetes mellitus patients c) type 2 diabetes patients not controlled by a sulfonylurea drug d) type 2 diabetes patients not controlled by a biguanide drug Paget of 3 QP Code: 11207 JSS Academy of Higher Education and Research Second Year BDS (RS 1) Examination - December 2018 Subject: General & Dental Pharmacology & Therapeutics rime: 3 hours Max. Marks: 70 Your answers should be specific to the questions asked. Draw neat labeled diagrams wherever necessary. art | Multiple Choice Questions 10 Marks To be answered in OMR sheet art Il Long Essays 20 Marks To be answered in Answer | Short Essays 20 Marks Booklet Short Answers 20 Marks Part ultiple Choice Questions ote: 1. 2. 3. 4. The antidote used in the treatment of atropine poisoning is: 10 x 1=10 Marks Answer ALL the questions in the OMR Sheet given by using BLACK/BLUE BALL POINT PEN ONLY. Choose the ONE CORRECT ANSWER from the 4 choices given for each question. Maximum time for answering Part | is 10 minutes. At the end of 10 minutes, submit the OMR sheet to the Invigilator. a) physostigmine b) carbachol c) neostigmine d) adrenaline All are inhalational glucocorticoids EXCEPT: a) beclomethasone dipropionate b) budesonide ¢) prednisolone d) fluticasone Which is the long acting insulin analogue? a) regular insulin b) insulin lente c) insulin glargine d) insulin lispro Page 1 of 3 yr rime art |: oak wo 10 12 13 14 1§ 16. QP Code: 11207 58 Academy of Higher Education & Research, Mysuru J (Deemed to be University) Second Year BDS (RS 1) Examination — January 2021 Subject: General and Dental Pharmacology and Therapeutics 3 hours Max. Marks: 70 0 Mts (MCQ’s-valued separately) Max. Marks: 10 2 Hrs & 50 Mts (Written) Max. Marks: 60 Part Il LONG ESSAYS 2x10=20 Marks Classify anti-hypertensive drugs. Explain the mechanism of action, uses (5+5) and adverse effects of calcium channel blockers. Enumerate the common oral conditions in dentistry. Explain the role of (4+6) various anti-microbials in the management of these conditions. SHORT ESSAYS 4x5= 20 Marks Combined effect of drugs. Mechanism of action, uses and adverse effects of lignocaine. Haematinics. Bronchodilators. SHORT ANSWERS 10X2=20 Marks Write TWO advantages of sublingual route with TWO examples. Define teratogenicity. Give ONE example. Define astringent. Give ONE example. Name TWO skeletal muscle relaxants with TWO uses. Name TWO osmotic purgatives. Mention TWO specific adverse effects Name TWO coagulants. Give TWO specific uses Name TWO antiviral drugs belonging to two different groups. Write ONE use of each. List the adverse effects of tetracyclines on bone and teeth Name TWO fluoroquinolones. Write TWO specific adverse effects. Write the mechanism of action and uses of desferrioxamine Page Lof1 QP Code: 1207 JSS UNIVERSITY, MYSURU Second Year BDS Examination - November 2015 Subject: General Dental Pharmacology & Therapeutics Note: All questions are ¢ p Is compulsory. Your answors should be Specific to the questions asked. raw neat labeled diagrams wherever necessary. Time: 3 hours Max. Marks: 70 |. LONG ESSAYS . 2x10=20 Marks 1. Describe different t yPes of mouth 5 ae . mouth wash. wash. Describe the excipients used in a is) Classify semisynthetic penicillins. Describe their therapeutic uses. ll. SHORT ESSAYS 6x5=30 Marks Classify hypnotics. Describe therapeutic uses of benzodiazepines. Classify B blockers. Describe their therapeutic uses. Classify skeletal muscle relaxants. Describe their clinical uses. Oa Bw Enumerate Parenteral iron preparations. Mention indications for parenteral iron therapy. 7. Classify antiemetics. Describe therapeutic uses and adverse drug reaction of metaclopramide. 8. Describe therapeutic uses of glucocorticoids. lll. SHORT ANSWERS . 10x2=20 Marks 9. Name four drugs used in leprosy. 10. Name four groups of drugs used in peptic ulcer. Mention one example each. 11. Name two groups of bronchodilators giving one example each. 12. Give four examples of receptor mediated antagonism. 13. Highlight differences between an antiseptic and disinfectant. 14. Name two local anaesthetic agents commonly used in dentistry. Name one adverse drug reaction of each. 15. Mention two long term adverse effects of phenytoin and important measures to prevent them. 16. Enumerate four uses of aspirin. 17. Classify antihypertensive agents based on their mechanism of action. 18. Describe in brief mechanism of action of oral anticoagulants. Mention antidote of warfarin. fhe QP Code: 1207 JSS UNIVERSITY, MYSURU Second Year BDS Examination - June 2016 Subject: General & Dental Pharmacology & Therapeutics Note: All questions are compulsory. Your answers should be specific to the questions asked. Draw neat labeled diagrams wherever necessary Max. Marks: 70 ne: 3 hours LONG ESSAYS 2x10=20 Marks 1. Classify antiseptics and disinfectants used in dentistry. Describe the (5+5) pharmacology of oxidizing agents and halogens. 2. Classify beta-lactam antibiotics. Describe the mechanism of action, (2+24+2+2+2) anti-microbial spectrum, adverse effects and therapeutic uses of ampicillin. 6x5=30 Marks . SHORT ESSAYS 3. Mechanism of action and therapeutic uses of physostigmine. 4. Differences between competitive and non-competitive antagonism. 5. Mechanism of action and therapeutic uses of ramipril 6. Adverse effects and therapeutic uses of carbamazepine 7. Mechanism of action and adverse effects of metronidazole. 8. Mechanism of action of DPP-4 inhibitors and status in therapy of T2DM. 40x2=20 Marks ll. SHORT ANSWERS 9. Mention four adverse effects of thiazide diuretics. 40. Mention four therapeutic uses of anti-histaminics 11. Mention four drug interactions with warfarin. 12. Mention the ingredients of anti H pylori treatment. 13. Name the drugs in AKT 4 kit. 14. Mention four contra-indications to tetracyclines. 15. Mention four therapeutic uses of methotrexate. . 18. Mention four uses of vitamin D, excluding rickets. 17. Basis of combining adrenaline with local anaesthetic. 18. Mention four adverse effects of aminoglycosides. thie 10. “Pe |) Biotransformation of a medicinal substance results in a) faster urinary excretion b) slower urinary excretion c) easier distribution in organism d) higher binding to membranes All are cardioselective beta blockers EXCEPT a) metaprolol b) bisoprolol c) acebutalol d) propranolol Which is the mast cell stabilizer used in Prophylaxis of asthma? a) terbutaline b) aminophylline Cc) sodium cromoglycate d) tiotropium bromide All are atypical antipsychotics EXCEPT a) amisulpiride b) olanzapine c) quetiapine d) haloperidol The site of action of thiazide diuretic is: a) Na ‘- Cl transporter b) Na‘-K*-2CI transporter Cc) Na’-H’ antiporter 9) Na"-HCO3° symporter All are antileprosy drugs EXCEPT: a) dapsone b) clofazimine Cc) rifampin d) amphotericin B B-lactum antibiotics do not include the following: a) streptomycin b) cephalosporins Cc) carbapenems d) monobactams QP Code: 11207 Subject: General and Dental Pharmacology and Therapeutics Part Il LONG ESSAYS Classify non-steroidal anti-inflammatory drugs. Describe the mechanism of action, therapeutic uses and adverse effects of aspirin. Explain the various routes of drug administration with suitable examples. Mention the advantages and disadvantages of oral route. SHORT ESSAYS Enumerate calcium channel blockers and write their therapeutic uses. Antimicrobial prophylaxis in dentistry. Therapeutic uses and adverse effects of tramadol. What are abrasive agents? Give examples and therapeutic uses. SHORT ANSWERS Two indications and two contraindications of beta blockers. Two merits and two demerits of parenteral route of drug administration. Two therapeutic uses and two adverse effects of ACE inhibitors. Rationale for giving adrenaline along with local anesthetics. Four adverse effects of glucocorticoids. Two aminoglycosides and two of their adverse effects. Four first line anti-tubercular drugs. Two proton pump inhibitors and their therapeutic uses. Two antiseptics and two disinfectants used in dental practice. Four adverse effects of phenytoin. eared 2x10=20 Marks (2+3+2+3) (7+3) 4x5= 20 Marks 10X2=20 Marks Page 3 of 3 ~~ QP Code: 11207 ject! General & Dental Pharmacology & Therapeutics J Part Il LONG ESSAY 2x10=20 Marks Classify anti-hypertensives with examples. Explain the mechanism of (3+2+2+3) action, uses and adverse effects of angiotensin converting enzyme (ACE) inhibitors. Define oxidizing agents. Write examples, mechanism of action and uses (1+2+2+2+3) of the same. Add a note on styptics. SHORT ESSAY 4x5= 20 Marks Uses of atropine and its substitutes. Group, mechanism of action, adverse effects and uses of morphine. (1+1+1+2) Compare and contrast d-tubocurarine and succinylcholine. Mechanism of action, uses and adverse effects of pantoprazole. ~ (2+2+1) SHORT ANSWERS 40X2=20 Marks Treatment of digoxin toxicity. Uses and two adverse effects of glucocorticoids. Advantages of intravenous route of drug administration. Teratogenicity. Tachyphylaxis. First dose phenomenon. Four drugs used for prophylaxis of migraine. Indications for parenteral iron preparations. Mention antidotes for the following : a) Paracetamol poisoning b) Morphine poisoning c) Diazepam poisoning d) Iron poisoning. Name two anti-human immunodeficiency virus (HIV) drugs. Tonk 5.5. DENTA J fl SAY} $.S5.NAGAR, MYSO! 70 615 “nvsone-370 615 | Page 3 of 3

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