DRUGS AND THEIR

SPECIFIC SYNDROMES
S. NO. NAME OF DRUG SYNDROMES/ADVERSE EFFECT
1. Aspirin Reye’s syndrome

e s
2. Chloroquine Irritable bowel syndrome

s s
3. Montelukast and Churg Strauss syndrome

4.
Zafirlukast

c c la
d
Oral contraceptives Cushing’s syndrome

g
5. Calcium carbonate Milk alkali syndrome

t @
6. Pethidine ‘Serotonin syndrome’
7.

ig h
Haloperidol or pimozide Gilles de la tourette syndrome

r
y
8. Dapsone Sulfone syndrome

o p
9. Adefovir dipivoxil Flu syndrome

c
10. Quiniodochlor Caused a neuropathic syndrome
11. Pemetrexed Hand-foot syndrome
12. Mitomycin C Haemolytic-uremic syndrome
13.

s
Tretinoin ‘retinoic acid syndrome

s e
14. ACE-inhibitors Dry cough

la s
15. Amphotericin- B, Nephrotoxicity
Erythromycin

d c c
g
16. Antipsychotics Sedation, orathostatic, hypotension, tardive dyskinesia

@
17.

t
Atropine Dryness of mouth

h
18.

g
Chlorambucil Alopecia
19.

y r i
Chloramphenicol Grey baby syndrome, bone marrow depression

p
20.

o
Clofazimine Pigmentation of skin discolouration of urine

c
21. Clozapine Agranulocytosis
22. Ethambutol Optic neuritis
23. Isoniazid Peripheral neuritis

s
24. Minoxidil phenytoin anabolic steroids Hirsutism
25. Morphine

s
Constipation
s e
la
26. Penicillin-G Jarischhexiemer reaction
27. Quinidine

d c c
Cinchonism

g
28. Quinine sulphate Black water fever

t @
29. Repaglinide Althralgia
30.

r ig h
Rosiglitazone Anemia weight gain

y
31. Spironolactone, Cimentidine Gynacomastia

o p
32. Streptomycin chloroqune furosemide Ototoxicity (Damage of 8th cranial

c
never)
33. Sulfonylureas derivatives Bone marrow depression
34. Spironolactone, Cimentidine Gynacomastia

s
35. Streptomycin chloroqune furosemide Ototoxicity (Damage of 8th cranial
never)

s s e
la
36. Sulfonylureas derivatives Bone marrow depression
37. Tetracyclines

d c c
Fanconi syndrome, Discolouration of

@ g teeth

t
38.

h
Thalidomide Phocomelia (seal-like limbs )

ig
39.

r
Sulfonamides, Cephalosporin, Stevan-johnson syndrome

o p yAllopurinol

c
40. Metoclopramide, Haloperidol Extrapyramidal reaction
41. Tetracyclines sympathomimetics Pseudotumor cerebri
42. Hydralazine, Blemycin, Asparginase Systemic lupus erythrmatous

e s
syndrome
43. Simvastatin, Daptomycins Myopathy

s s
la
44. Glucocorticoides, Thyroxine, Heparin Osteoporosis
45. β-blocker, Clonidine, Diuretics

d c c
Impotence

g
46. Cephalosporins, Alopurinol Interstitial nephritis
47.

t @
Primaquine, Chloramphenicol

h
Haemolytic anemia

ig
48. Phenothiazianes, TCAs (Tetracyclin) Hyperprolactinemia
49.

p y r
Vancomycin Red man syndrome

o
50. Nitorfurantoin Loffler's syndrome
51.
c Benzocaine, Dapsone Blue baby syndrome
53. Doxorubicin Hand foot syndrome

s
54. Cisplatin and Bleomycin Raynaud syndrome

e
Calcitonin, Phenytoin Hypocalcemia

s
55.

s
Corticosteroids, β-blockers Hypertriglyceridemia

la
56.

c
57. Theophylline, Morphine Hypotension
58.

g
Oral hypoglycemic, Insulin, Quinine
d c
Cocaine, Cyclosporine, MAO inhibitors Hypertension
Hypoglycemia

@
59.

h t
60. Vinca alkaloids, Cyclophosphamide Inappropriate ADH secretion
61.

r ig
Streptomycin

y
Ototoxicity

p
62. Rifampicin Jaundice
63.
64. c o
Bacitracin, Polyenes, Polypeptide Nephrotoxicity
Polymyxin B Neurotoxicity, Nephrotoxicity
65. Anthracycline Cardiotoxicity
(Doxorubicin Daunorubicin)

s
66. Busulphan, Bleomycin Pulmonary fibrorsis
67. Vincristine, vinblastine, Vinorelbine

s
Peripheral neuropathy

s e
la
68. Methotrexate Megaloblastic aneamia, Hepatotoxicity,

c
Obstructive nephropathy

c
69. Cyclophosphamide, Ifosfamide Haemorrhagic cystitis, Alopecia
70.
71.
Cisplatin

g
5-Flourouracil, Capecitabine, d
Emesis, Nephrotoxicity, Neuropathy,
Hand and foot syndrome, Neurotoxicity

t
Fludarabine

h @
g
72. 6- Mercaptopurine, 6-Thioguanine Hepatotoxicity
73.

r i
Paclitaxel, vincristine

y
Peripheral neuropathy,

p
Hypersensitivity

o
74. Docetaxel Peripheral neuropathy, Fluid retention
75.
c Doxyfluridine Bone marrow depression, Hearing loss,
Neuritis.