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Syllabus:
9.1 Transport in animals
The arrows show the direction of blood flow. The arrow begins at the lungs- blood flows
into the left side of the heart from the lungs and then out to the rest of the body. It is
brought back to the right side of the heart, before going back to the lungs again.
Blood in the left hand side of the heart has come from the lungs. It contains
oxygen, which is picked up by the capillaries surrounding the alveoli. It is called
oxygenated blood asit is rich in oxygenand this blood is bright red in color.
This oxygenated blood is then sent around the body.
In a fish, the low pressure blood just carries on around the body. So blood travels
very slowly to a fish’s body organs than it does in a mammal.
Increases the delivery of oxygen to the tissues for respiration: metabolically
active tissues need a lot of oxygen to be delivered very quickly. This delivery is
much more effective in a mammal than in a fish, because of the high pressure
blood carries around the body of a mammal.
The heart:
Part8_human heart.flv
Internally the heart is divided into four chambers-the two upper chambers are
called atria and the two lower chambers are called ventricles.
The chambers on the left hand side are completely separated from the ones on
the right hand side by a septum. The septum separates and prevents mixing the
oxygenated blood in the left side of the heart from the deoxygenated blood in the
right side of the heart.
Both the atria receive blood-the left atrium receives blood from the pulmonary
veins, which come from the lungs. The right atrium receives blood from the rest
of the body, arriving through the vena cavae.
From the atria, blood flows into the ventricles.
The place where the pulmonary artery and aorta opens in to the ventricles, there are
valves called semilunar valves. They are the pulmonary semilunar valve and the
aortic semilunar valve. They prevent the back flow of blood from these arteries back
to the ventricles during ventricular relaxation.
Cardiac cycle: the changes that occur in the heart during one heart beat. It involves
three changes-diastole, atrial systole and ventricular systole.
HA6_A.exe
Atrial systole:
The muscles of the atria contract and muscles of the ventricles remain relaxed.
Blood is forced from the atria into the ventricles through the open AV valves.
The semilunar valves remain shut.
The valves in the veins are forced to shut by the pressure of the blood,
stopping the blood from flowing back into the veins.
Ventricular systole:
The muscles of the ventricles contract.
The semilunar valves are forced open by the pressure of blood, forcing
blood out of the ventricles into the arteries- from the right ventricle into the
pulmonary artery and from the left ventricle into the aorta.
The AV valves are forced shut by the pressure of the blood.
The best way to measure the rate of heart beat is to take the pulse rate. The
ripple of pressure that passes down an artery as a result of the heart beat can be
felt as a ‘pulse’ when an artery is near the surface of the body. So the pulse rate
of a person is same as his heart rate.
We can find a pulse wherever there is an artery near to the surface of the skin.
Two suitable places are the radial artery inside your wrist, and carotid artery just
to the side of the big tendons in the neck.
[Use the first two fingers of your right hand and rest them on the inside of your
wrist.Feel for the tendon near the outside of your wrist.If you rest your fingers
lightly just over this tendon, you can feel the artery in your wrist pulsing as your
heart pumps blood through it].
ECG (Electrocardiograph):
In a hospital, the activity of the heart can be recorded as an ECG.
Little electrodes are stuck onto the person’s body, and the electrical activity in the
heart is recorded as a kind of graph.
Heart sounds:
o These can be heard using a stethoscope.
o A healthy heart produces a regular ‘lub-dub’ sound.
o The first ‘lub’ sound is caused by the closure of the AV valves separating the
atria from ventricles.
o The second ‘dub’ sound represents the closure of the semilunar valves at the
entrance of the pulmonary artery and aorta.
o Observation of irregular sounds may indicate an irregular heart beat which may
point to a problem with faulty valves.
Paced maker:
the rate at which the heart beat is controlled by a patch of muscle in the right
atrium called the pace maker. The pace maker sends electrical signals through
the walls of the heart at regular intervals which make the muscle contract.
The pace maker’s rate and therefore the rate of heart beat changes according to
the needs of the body.
Pressure changes in the ventricles and atria during a single heart beat
Surgery: it is needed when the medication fails. Surgery can be done in the
following ways:
1. Coronary bypass operation:
the surgeon removes a section of blood vessel from a different part of the
body, such as the leg.
the blood vessel is then attached around the blocked region of artery to
by-pass it, allowing blood to pass freely.
This is a major operation because it involves open heart surgery.
2. Stents:
o Stent is a wire-mesh tube which is inserted inside the artery to keep it open.
o A stent can be expanded and left in place. It then acts as scaffolding keeping the
blood vessel open and maintaining the free flow of blood.
Heart transplant: in severe cases the patient may require a complete heart transplant.
This is always risky because:
-there are never enough organs available for all the patients that require them.
-the transplanted organ will be rejected by the recepient’s immune system.
-the recipient will need to take drugs to suppress the immune system for the rest
of their life.
Blood vessels
There are three main kinds of blood vessels-arteries, capillaries and veins.
Arteries :
Blood vessels that carry blood away from the heart to the limbs and organs of the
body.
The blood in the arteries, except for the pulmonary arteries, is oxygenated.
Blood flows through the arteries at high pressure because it has been forced out
of the heart by the contraction of the muscular ventricles. Arteries therefore need
very strong walls to withstand the high pressure of blood flowing through them.
The blood does not flow smoothly through them, it pulses through because the
ventricles contract and relax.
Capillaries:
Arterioles divide repeatedly to form a branching network of microscopic vessels
passing through the cells of every living tissue. These very tiny vessels are called
capillaries.
The function of the capillary is to supply all cells with their requirements-nutrients,
like glucose, amino acids, oxygen and other materials like inorganic ions,
vitamins and water, and to take away their waste materials like CO2.
Their walls are permeable and one cell thick, with no muscle or elastic tissue.
Veins:
veins carry blood from the tissues towards the heart.
The blood in most veins is deoxygenated and contains less food but more carbon
dioxide than the blood in arteries.
Blood flow through the veins is at very low pressure and it flows more slowly and
smoothly. Thus there is no need for them to have a thick, strong and elastic wall.
Thin outer wall, containing very less muscle and elastic tissue than arteries.
Have wide lumen which helps to keep the blood moving easily through them.
Valves present to stop blood flowing backwards.
Blood is also kept moving in the veins in one direction (towards the heart) by the
contraction of muscles around them. The large veins in our legs are squeezed by our
leg muscles when we walk. This helps to push the blood back up to the heart.
Vein -Thin wall-mainly fibrous tissue, -As they carry blood at low pressure.
with little muscle or elastic fibres.
-Large lumen. -To reduce resistance to blood flow.
-Valves present. -To prevent back flow of blood and to
keep low-pressure blood moving in
one direction-to the heart.
Capillary Permeable wall, one cell thick -This allows diffusion of materials
with no muscle or elastic tissue. between the capillary and surrounding
tissues.
Narrow lumen only one red blood -White blood cells can squeeze
cell wide. between cells of the wall. Blood cells
pass through slowly to allow diffusion of
materials and tissue fluid.
arteries veins
Arterioles:
o they are blood vessels which are produced by the division and branching of large
arteries.
o Like arteries they are strong, and have a relatively thick wall, and contain more
smooth muscle but have less elastic tissue.
Function:
o regulate the flow of blood into different tissues.
o When the muscle fibres of the arterioles contract, they make the vessels
narrower and restrict the blood flow, a process called vasoconstriction.
o In this way, the distribution of blood to different parts of the body can be
regulated. Example, if the body temperature drops below normal, arterioles in the
skin constrict to reduce the amount of blood flowing through capillaries near the
skin surface.
Function: they dilate to allow blood to bypass the capillaries in certain areas. This helps
to reduce further heat loss. Example, in warm blooded animals, the shunt vessels dilate
in response to cold, thereby cutting off the blood flow to the extremities and preventing
heat loss.
The main blood vesselsto and from the heart, lungs, liver and kidney:
Hepatic portal
vein-from gut to
liver
Part9_centrifugation of blood.flv
Blood platelets:
-small pieces of special blood cells budded off in the red bone marrow
-they contain no nucleus.
-function: help to clot the blood at wounds and to stop the bleeding.
This chemical set off a chain of enzyme catalyzed reactions which cause the
fibrinogen, a soluble protein in the blood plasma, to change into insoluble fibrin.
Fibrinogen fibrin
The clot finally dries to form a scab which stops further loss of blood.
Plasma:
-the liquid part of the blood which forms 50% of blood volume.
-it is water with a large number of substances dissolved in it, like ions of sodium,
potassium, calcium, chloride and hydrogen carbonate; proteins such as
fibrinogen, albumin and globulins; food substances such as amino acids, glucose
and lipids; hormones; excretory products like urea and carbon dioxide.
Tissue fluid: it is the fluid that surrounds all the cells in the body. It is formed from
blood plasma that leaks out of capillaries.
Not all the tissue fluid surrounding the body tissues returns to the capillaries. Some of it
enters blind ended, thin walled vessels called lymphatics. They have tiny valves that
allow the tissue fluid to enter but will not let the lymph pass out again. The lymphatics
Lymph: when tissue fluid in the lymphatic vessels is called lymph. It consists of plasma
and white blood cells, but has no red blood cells or large plasma proteins.
The lymphatic system has no pump, like the heart, to push lymph around the lymphatic
system so the flow of lymph is slow. The lymph vessels pass alongside muscles which
squeeze on the lymph vessels when the muscles contract. This helps to make the
lymph flow. Valves in the lymph vessels make sure that the lymph can only flow one
way.
Lymph flows from the tissues to the heart. The large lymph vessels empty the lymph
into subclavian veins, under the collar bones. Here the lymph mixes with the blood
before joining the vena cava just before it enters the heart.
Lymph nodes:
Small swellings at intervals along the length of the lymph vessels. Lymphocytes
are stored in the lymph nodes and released into the lymph to finally reach the
blood system. There are also phagocytes in the lymph nodes.
They are an important part of body’s immune system. If bacteria enter a wound
and are not ingested by the WBCs of the blood or lymph, they will be carried in
the lymph to a lymph node and WBCs there will ingest them. Thus the lymph
nodes form part of the body’s defence system against infection.
Functions of lymph:
Question: 1
Qn.3
3. The diagram shows cross-sections of three types of blood vessel (not drawn to the same scale).
Complete table 3.1 to give three differences between the pulmonary artery and pulmonary vein.
(ii) The volume of blood pumped out of the heart per minute is known as the cardiac output.