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Robert G. Frykberg and Jaminelli Banks (2015). Challenges in the High treatment
treatment of chronic wounds. Advances in wound care, volume 4, number 9 COSTS
BACKGROUND
CHRONIC WOUND INTRODUCTION
• ACUTE wound becomes CHRONIC if healing is not achieved after 4 WEEKS of treatment.
• CHRONIC WOUNDS DEFINITION: wound FAILED TO PROCEED through the orderly process
that produces satisfactory ANATOMIC & FUNCTIONAL INTEGRITY.
• Majority not healed in 3 months: DIABETIC FOOT ULCER, CHRONIC VENOUS
INSUFFICIENCY, DECUBITUS ULCER
Fase penyembuhan luka seluler, biokimia dan mekanik Histologi A. Fase hemostasis/inflamasi. B. Fase inflamasi lanjut.
C. Fase proliferasi (angiogenesis da sintesis kolagen)
WOUND MECHANICAL STRENGTH
• Fully healed wound: 75% to 80% of a
normal tissue.
• Delayed healing: decreased wound-
breaking strength (nutritional
deficiencies, infections, or severe
trauma).
• Impaired healing: failure to achieve
mechanical strength equivalent to
normally healed wounds (diabetes,
steroid, radiotherapy).
CHRONIC WOUND PROBLEM
CHRONIC WOUND PROBLEM
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