ASHP Midyear Clinical Meeting
Impact of COVID-19 vaccination status on COVID-19 hospital admissions at a
Background
● The Center of Disease Control and Prevention (CDC)
asserts COVID-19 vaccination reduces the risk of
becoming hospitalized with COVID-191
● The CDC reported 8,579 COVID-19 related hospital
admissions in New York from May 3, 2021 through July
19, 2021 1
● Of these hospitalized patients, 14.8% (1,271) were fully
vaccinated compared to 85.2% (7,308) unvaccinated1
● Studies have also drawn association between the risk of
COVID-19 hospitalization and varying chronic health
conditions and patient characteristics 2
Purpose
● To evaluate the vaccination status of COVID-19 positive
hospitalized patients and compare to the New York CDC
data
Methods
● Retrospective chart review of all patients discharged or
expired with a diagnosis of active COVID-19 infection
● Patients were identified using computerized extraction
filtered solely by diagnosis of active COVID-19 infection
between March 1, 2021 and September 22, 2021
● Vaccination status was determined using provider
documentation
● Patient characteristics were also collected:
Intensive care unit (ICU) Age
admission
Body mass index (BMI) Hyperlipidemia
Chronic obstructive pulmonary disease Type II diabetes (T2DM)
(COPD)
community hospital
Authors: Kyle Starkus, PharmD; Brian Chang, PharmD; Andrew Harpenau, PharmD
Affiliation: Ascension St. Vincent Evansville
Results Discussion
● Of the 169 patients hospitalized with a COVID-19
vaccination status, the vast majority were unvaccinated
● Vaccination status appears to have had no impact on
the severity of illness in regards to mortality and ICU
admission
● Emphasis could be placed on those unvaccinated with
HTN or COPD, as the risk of hospitalization was reduced
in those vaccinated with these conditions
● With the emergence of vaccine booster doses, future
research could expand upon this data and evaluate the
risk of hospitalization in those fully vaccinated with and
without a booster
● The average patient hospitalized with COVID-19 had a
BMI just below morbid obesity
Conclusion
● The effectiveness of COVID-19 vaccination on
preventing hospitalization closely resembles the CDC
findings out of New York
● This data may be made into an informational handout
and distributed to providers
● The prevalence of certain chronic health conditions may
serve to further emphasize the benefit of COVID-19
vaccination
● Emergence of virus variants is a confounding variable,
although some variant-prevalent months were included
Mortality References
1. “New Covid-19 Cases and Hospitalizations among Adults, by Vaccination Status - New York, May 3–July 25,
2021.” Centers for Disease Control and Prevention, Centers for Disease Control and Prevention, 16 Sept. 2021,
Hypertension (HTN) https://www.cdc.gov/mmwr/volumes/70/wr/mm7034e1.htm.
2. “People with Certain Medical Conditions.” Centers for Disease Control and Prevention, Centers for Disease
Control and Prevention,
https://www.cdc.gov/coronavirus/2019-ncov/need-extra-precautions/people-with-medical-conditions.html.
The authors have no conflict of interest.